The regulatory role of placental extracellular vesicle on trophoblast and endothelial cell functions by Kunfeng Bai, Kunfeng Bai, Xintong Li, Yanjie Guo, Ye Shang, Leqian Lin, Philip C. N. Chiu, Philip C. N. Chiu, Cheuk-Lun Lee

“…During pregnancy, EVs are secreted by the syncytiotrophoblast layer of the placenta villi, where they mediate the functions of resident leukocytes and invading extravillous trophoblasts (EVTs) in the decidua. …”
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Modeling critical dosing strategies for stromal-induced resistance to cancer therapy by Anna K. Kraut, Colleen M. Garvey, Carly Strelez, Shannon M. Mumenthaler, Jasmine Foo

“…We propose a mathematical model for a common tumor-stromal interaction motif where stromal cells secrete factors that promote drug resistance. We demonstrate that the presence of this interaction modulates the therapeutic dose window of efficacy and can lead to nonmonotonic treatment response. …”
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Exploring RNA cargo in extracellular vesicles for pleural mesothelioma detection by Agnieszka Kraft, Michaela B. Kirschner, Vanessa Orlowski, Manuel Ronner, Caroline Bodmer, Valentina Boeva, Isabelle Opitz, Mayura Meerang

“…In this study, we characterized the transcriptomic profile of EVs secreted by PM primary cells and explored their potential as a biomarker source for PM detection. …”
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CCR2 signaling regulates anti-chlamydia T cell immune responses in the airway. by Shuaini Yang, Jinxi Yu, Xue Dong, Jiajia Zeng, Lu Tan, Hong Zhang, Ruoyuan Sun, Yuqing Tuo, Jing Yang, Chunxiao Wan, Hong Bai

“…Moreover, ccr2 deficiency greatly diminishes STAT1 phosphorylation, a key regulator of IFN-γ secretion by Th1 cells. Meanwhile, we also observed a significant reduction in IFN-γ secretion by CD8+ T cells following ccr2 deficiency. …”
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Understanding the effectiveness of attachments in clear aligner therapy: navigating design, placement, material selection and biomechanics by Demir Gizem Boztaş

“…Clear aligner treatments have gained popularity due to their aesthetic advantages over traditional metal brackets. Attachments play a crucial role in enhancing the efficacy of treatment by addressing challenges posed by the flexibility of aligner materials. …”
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Resistance of Some Rice Varieties (Oryzae sativa Linnaeus) to the Brown Planthopper (Nilaparvata lugens Stal) using the Honey Dew Test by Widya Puspita Sari, James Rinaldi, Dedi Darmadi, Arneti Arneti

“…Keywords: Honeydew, resistant, secretion, susceptable,  sticky rice …”
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Effect of Different Nutritional Materials on Laccase Activity and Biomass Accumulation of the Auricularia cornea var. Li Strain by Xue Xiong, Peng Li, Zhun Xiang, Yao-Wei He, Xuan Zheng, Zhong-Xuan Liu

“…Li and identified culture substances that were beneficial for laccase secretion during different growth stages of the mushroom. …”
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Targeting adipocyte ESRRA promotes osteogenesis and vascular formation in adipocyte-rich bone marrow by Tongling Huang, Zhaocheng Lu, Zihui Wang, Lixin Cheng, Lu Gao, Jun Gao, Ning Zhang, Chang-An Geng, Xiaoli Zhao, Huaiyu Wang, Chi-Wai Wong, Kelvin W. K. Yeung, Haobo Pan, William Weijia Lu, Min Guan

“…Mechanistically, adipocyte ESRRA interferes with E2/ESR1 signaling resulting in transcriptional repression of secreted phosphoprotein 1 (Spp1); yet positively modulates leptin expression by binding to its promoter. …”
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Flavones enrich rhizosphere Pseudomonas to enhance nitrogen utilization and secondary root growth in Populus by Jiadong Wu, Sijia Liu, Haoyu Zhang, Sisi Chen, Jingna Si, Lin Liu, Yue Wang, Shuxian Tan, Yuxin Du, Zhelun Jin, Jianbo Xie, Deqiang Zhang

“…Moreover, we confirm that Pseudomonas is strongly associated with tricin and apigenin biosynthesis and identify that gene GLABRA3 (GL3) is critical for tricin secretion. The elevated tricin secretion via constitutive transcription of PopGL3 and Chalcone synthase (PopCHS4) can drive Pseudomonas colonization in the rhizosphere and further enhance poplar growth, nitrogen acquisition, and secondary root development in nitrogen-poor soil. …”
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How Rural Society Was Occupied by Kotryna Bėčiūtė

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Efficiently regulating the electrochromic behavior of naphthalene-diimide-based zirconium-organic frameworks through linker installation by Cha Li, Hao Zhang, Feifan Lang, Yanghe Liu, Lin Xu, Xiao-Juan Xi, Yang Li, Jiandong Pang, Hong-Cai Zhou, Xian-He Bu

“…Herein, we design a redox-active Zr-MOF with coordination unsaturated pockets, termed NKM-908, based on a naphthalene diimide containing tetratopic carboxylate ligand. …”
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Acute stimulation of PBMCs drives switch from dopamine-induced anti- to proinflammatory phenotype of monocytes only in women by Leonie Fleige, Silvia Capellino

“…We found a B cell-driven downregulation in cytokine secretion of monocytes exclusively from women under physiological conditions in vitro. …”
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What Do Gases in the Large Intestine Have to Do with Health? by Klaudia Pawełek, Patrycja Kinga Marta, Filip Maciej Huzarski, Gabriela Monika Ferfecka, Magdalena Rosa-Bończak, Agata Ossolińska, Weronika Kłosowicz, Oliver Carlton, Lucyna Stolarska, Natalia Morawiecka

“…The gut-brain axis, regulated by the nervous system and gut microbiota, influences intestinal motility, hormone secretion, and metabolic processes. Gut microorganisms produce short-chain fatty acids (SCFAs), which play a significant role in regulating energy homeostasis and enteroendocrine hormone secretion. …”
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Infants’ digestion at breast feeding (enzymological viewpoints) by G. F. Korot'ko

“…At child breast milk nutrients are hydrolysed in natural conditions by milk enzymes, secretions of digestive glands and secretory intestinal epithelial cells as autolytic-induced digestion with subsequent addition and advance of autologous digestion. …”
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Challenges in diagnosis and treatment of cushing disease in a 12-year-old boy. Case report by Agim Gjikopulli, Sonila Tomori, Marjeta Tanka, Donjeta Bali

“… Cushing’s Disease (CD), defined as hypercortisolism caused by excess Adrenocorticotropic Hormone (ACTH) secretion by a pituitary corticotroph adenoma, rarely presents in the pediatric age range. …”
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Characterization of Escherichia coli outer membrane vesicles and the impact of pathogenic ones on NLR signaling pathways by Roghayeh Mohammadzadeh, Ava Behrouzi, Farzam Vaziri, Seyed Davar Siadat

“… Background and Objectives: The secretion of outer membrane vesicles (OMVs) is a universal event among bacteria. …”
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Does Fetal Fibronectin Predict the Delivery Route in Nulliparous Women at Postterm Induced by Dinoprostone? by Hale Goksever Celik, Engin Celik, Gonca Yetkin Yildirim

“…Recently, alternative approaches such as transperineal ultrasound, fetal fibronectin test in cervicovaginal secretions have been investigating for the prediction of the delivery route. …”
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Correlation between shear bond strength and degree of conversion of four orthodontic adhesives. by Hangaw Tariq Ibrahim, Bayan Abdulla Hassan

“…Methods: Forty human upper first premolars, divided into four Groups (n = 10) were bonded with metal brackets using four different adhesives. Brackets were debonded in shear on an Instron universal testing machine with a crosshead speed of 1 mm per minute. …”
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Nocturnal Light Pollution Synergistically Impairs Glucose Metabolism With Age and Weight in Monkeys by Shuxing Wang, Xuange Cheng, Zihao Liang, Zhenyi Chen, Jiankai Zhang, Qiang Xu

“…Data pertaining to the mortality rate of preexisting diabetes, incidence of light-induced diabetes and IGT, and alterations in insulin secretion were collected and analyzed. The results show that nocturnal light (1) caused premature deaths in individuals with preexisting diabetes; (2) intensity-dependently induced diabetes and IGT in previous healthy monkeys; (3) intensity-dependently reduced melatonin secretion; (4) had a synergistic impairing effect on glucose metabolism with aging and weight; and (5) although monkeys would eventually adapt to the environment, the disrupted glucose metabolism would not fully recover in most individuals. …”
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