κ-Carrageenan Enhances Lipopolysaccharide-Induced Interleukin-8 Secretion by Stimulating the Bcl10-NF-κB Pathway in HT-29 Cells and Aggravates C. freundii-Induced Inflammation in M... by Wei Wu, Zhanghe Zhen, Tingting Niu, Xiaojuan Zhu, Yuli Gao, Jiangyan Yan, Yu Chen, Xiaojun Yan, Haimin Chen

“…Interestingly, κ-carrageenan competitively blocked the binding of FITC-LPS. Furthermore, pretreatment with κ-carrageenan for one week previous to gavage with C. freundii DBS100 markedly aggravated weight loss, mortality, and colonic damage. …”
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Dynamic Proteomic Analysis of Pancreatic Mesenchyme Reveals Novel Factors That Enhance Human Embryonic Stem Cell to Pancreatic Cell Differentiation by Holger A. Russ, Limor Landsman, Christopher L. Moss, Roger Higdon, Renee L. Greer, Kelly Kaihara, Randy Salamon, Eugene Kolker, Matthias Hebrok

“…In addition, LAMA2 partially blocks cell culture induced beta cell dedifferentiation. …”
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Advanced Microgrid Protection Utilizing Zero Sequence Components With Hard-Ware-in-the-Loop Testing by Zahra Ghanem, Feras Alasali, Naser El-Naily, Hassen Loukil, Haytham Y. Mustafa, Saad M. Saad, Abdelaziz Salah Saidi, William Holderbaum

“…Secondly, the study demonstrates the use of Configurable Function Blocks (CFCs) in digital relays to dynamically adjust relay settings based on zero sequence current detection. …”
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The production process of chepa shutki: A traditional Bangladeshi fermented fish product by Jasmin Ara Farhana, Sijmen E. Schoustra, Ferdous Ahamed, Bas Zwaan, Oscar van Mastrigt

“…After washing, sun drying, soaking and overnight storage, fermentation takes place in airtight earthen pots (locally called motka) whose micropores are blocked with fish oil to ensure anaerobic conditions. …”
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Frequent mutation of K-RAS in addition to BRAF V600E in Ameloblastoma – An immunohistochemical study by Aishwariya Mohanty, Abikshyeet Panda, Pallavi Mishra, Lipsa Bhuyan, Harish Kumar

“…Methods: 30 formalin-fixed paraffin-embedded blocks of histopathologically diagnosed cases of Ameloblastoma were taken as samples. …”
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Caerin 1.1/1.9-mediated antitumor immunity depends on IFNAR-Stat1 signalling of tumour infiltrating macrophage by autocrine IFNα and is enhanced by CD47 blockade by Junjie Li, Yuandong Luo, Quanlan Fu, Shuxian Tang, Pingping Zhang, Ian H. Frazer, Xiaosong Liu, Tianfang Wang, Guoying Ni

“…Interestingly, F1/F3 upregulates CD47 level on tumour cells; and blocking CD47 increases F1/F3-mediated antitumor responses. …”
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A Synoptic- and Remote Sensing-based Analysis of a Severe Dust Storm Event over Central Asia by Parya Broomandi, Kaveh Mohammadpour, Dimitris G. Kaskaoutis, Aram Fathian, Sabur F. Abdullaev, Vladimir A. Maslov, Amirhossein Nikfal, Ali Jahanbakhshi, Bakhyt Aubakirova, Jong Ryeol Kim, Alfrendo Satyanaga, Alireza Rashki, Nick Middleton

“…The prevailing meteorological conditions showed an intensification of air subsidence over eastern Kazakhstan, featured in a typical omega-blocking system over the region and two troughs to its west and east axis, one day before the dust storm. …”
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Combined blockade of GPX4 and activated EGFR/HER3 bypass pathways inhibits the development of ALK‐inhibitor‐induced tolerant persister cells in ALK‐fusion‐positive lung cancer... by Koh Furugaki, Takaaki Fujimura, Narumi Sakaguchi, Yasutaka Watanabe, Ken Uchibori, Eisaku Miyauchi, Hidetoshi Hayashi, Ryohei Katayama, Shigeki Yoshiura

“…GPX4 was found to be upregulated in DTP cells and to promote cell survival by suppressing reactive oxygen species (ROS) accumulation; GPX4 inhibitors blocked this upregulation and facilitated ROS‐mediated cell death. …”
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Anatomic characteristics of the lacrimal sac and adjacent bony structures–a computed tomographic-dacryocystography research by Xin-Han Cui, Yan-Wen Fang, Li-Min Zhang, Ji-Ni Qiu, Chao-Ran Zhang, Yan Wang

“…However, some were placed higher, with 7.63% blocked not lower than the OMT. There was a negative correlation between the diameter of the lacrimal sac and the level of obstruction (r= -0.35, P<0.01). …”
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3D Fusion Framework for Infarction and Angiogenesis Analysis in a Myocardial Infarct Minipig Model by Xu Zhenzhen PhD, Bo Tao PhD, MD, Yu Li MSc, Jun Zhang PhD, Xiaochao Qu PhD, Feng Cao PhD, Jimin Liang PhD

“…The presented framework is helpful in facilitating the study of the relationship between infarct territories and blocked coronary arteries as well as angiogenesis.…”
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A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapy by Gerhard Frey, Ana Paula G. Cugnetti, Haizhen Liu, Charles Xing, Christina Wheeler, Hwai Wen Chang, William J. Boyle, Jay M. Short

“…In healthy tissues, binding to EpCAM and CD3 is greatly reduced by a novel, dual CAB selection, where each binding domain is independently blocked by the presence of physiological chemicals known as Protein-associated Chemical Switches (PaCS). …”
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Differential effects of structurally different lysophosphatidylethanolamine species on proliferation and differentiation in pre-osteoblast MC3T3-E1 cells by Fumiaki Makiyama, Shiori Kawase, Aoi William Omi, Yusuke Tanikawa, Taishi Kotani, Teruki Shirayama, Naoyuki Nishimura, Taiga Kurihara, Naoto Saito, Jun Takahashi, Takeshi Uemura

“…MAPK/ERK1/2 activation by 16:0 LPE and 18:1 LPE was inhibited by the Gq/11 inhibitor YM-254890, while activation by 18:0 LPE was blocked by the Gi/o inhibitor pertussis toxin. Intracellular Ca2+ transients were triggered by 16:0 LPE and 18:1 LPE but not by 18:0 LPE, with YM-254890 suppressing these responses. …”
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Hole-selective-molecule doping improves the layer thickness tolerance of PEDOT:PSS for efficient organic solar cells by Bin Zhao, Xiaozhen Huang, Sein Chung, Min Zhang, Yufei Zhong, Anhai Liang, Zhenmin Zhao, Chaofeng Zhu, Jingjing Zhao, Seunghyun Kim, Jimin Kim, Ming Wang, Shilin Chen, Kilwon Cho, Yang Wang, Zhipeng Kan

“…When used in organic solar cells, poly (3,4-ethylenedioxythiophene)-poly (styrenesulfonate) (PEDOT:PSS) aligns interfacial energy levels, promotes hole extraction, blocks electrons, and optimizes the active layer’s morphology. …”
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Placenta-derived mesenchymal stem cells protect against diabetic kidney disease by upregulating autophagy-mediated SIRT1/FOXO1 pathway by Honghong Liu, Jiao Wang, Guanru Yue, Jixiong Xu

“…Moreover, downregulation of SIRT1 expression blocked the P-MSC-mediated enhancement of podocyte autophagy and improvement of podocyte injury. …”
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Contrasting vector competence of three main East African Anopheles malaria vector mosquitoes for Plasmodium falciparum by Prisca A. Kweyamba, Lorenz M. Hofer, Ummi A. Kibondo, Rehema Y. Mwanga, Rajabu M. Sayi, Fatuma Matwewe, Dickson W. Lwetoijera, Mgeni M. Tambwe, Sarah J. Moore

“…In conclusion, there is a need for comprehensive malaria control strategies targeting major malaria vector species, an update of malaria transmission models to consider vector competence and evaluation of malaria transmission blocking interventions in assays that include An. funestus mosquitoes.…”
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Optimizing lipopeptide bioactivity: The impact of non-ionic surfactant dressing by Ágnes Ábrahám, Gergő Gyulai, Judith Mihály, Andrea Horváth, Orsolya Dobay, Zoltán Varga, Éva Kiss, Kata Horváti

“…The physico-chemical properties of poloxamers vary depending on the length of the blocks. In our study, we experimented with different types and systematically investigated the variation of the critical micelle concentration (CMC) of poloxamers at 25 and 37 °C in different media. …”
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Structure and origin of Tuvan gene pool according to autosome SNP and Y-chromosome haplogroups by V. A. Stepanov, N. A. Kolesnikov, L. V. Valikhova, A. A. Zarubin, I. Yu. Khitrinskaya, V. N. Kharkov

“…Analysis of the composition of IBD-blocks on autosomes shows the maximum genetic relationship of the Tuvans with the Southern Altaians, Khakas and Shors, who were formed during the settlement of the Turkic groups of populations on the territory of the Altai-Sayan region. …”
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RMHA-Net: Robust Optic Disc and Optic Cup Segmentation Based on Residual Multiscale Feature Extraction With Hybrid Attention Networks by Mohammad J. M. Zedan, Siti Raihanah Abdani, Jaesung Lee, Mohd Asyraf Zulkifley

“…This network&#x2019;s encoder is designed based on advanced convolutional neural network (CNN) blocks that combine dilated convolution, which allows field-of-view expansion by capturing larger-scale features. …”
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Comprehensive three-dimensional microCT and signaling analysis reveal the teratogenic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on craniofacial bone development in mice by Xiao-ming Wang, Cai-ming Qin, Dou Li, Xin-ran Xu, Xiao-jing Pan, Hui Xue

“…The attenuation of AhR signaling significantly blocked the osteogenic toxicity, and partly restored the expressing level of estrogen receptor α (ERα). …”
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p38/JNK Is Required for the Proliferation and Phenotype Changes of Vascular Smooth Muscle Cells Induced by L3MBTL4 in Essential Hypertension by Chaowei Hu, Kun Zuo, Kuibao Li, Yuanfeng Gao, Mulei Chen, Roumu Hu, Ye Liu, Hongjie Chi, Hongjiang Wang, Yanwen Qin, Xiaoyan Liu, Jiuchang Zhong, Jun Cai, Xinchun Yang, Jing Li

“…Meanwhile, increased cell proliferation, advanced cell cycle progression, greater migratory capability, and synthetic phenotype were observed in L3MBTL4 overexpressed VSMCs, which could be blocked by either p38 or JNK inhibitor. Conclusions. …”
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