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5441
Comparison of Adaptation and Microleakage of CAD/CAM Restorations to Inlay Cavities Prepared by Using Different Finishing Methods
Published 2024-12-01“…Inlay restorations milled from feldspathic ceramic blocks were cemented with resin cement. Adaptation and microleakage of the restorations were evaluated by micro-CT. …”
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5442
Enhanced multiscale human brain imaging by semi-supervised digital staining and serial sectioning optical coherence tomography
Published 2025-01-01“…Additionally, we show that DS preserves geometry in 3D on cubic-centimeter tissue blocks, allowing for visualization of meso-scale vessel networks in the white matter. …”
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5443
By activating endothelium histone H4 mediates oleic acid-induced acute respiratory distress syndrome
Published 2025-01-01“…Changes in VE-cadherin were measured by western blot. Blocking antibodies against TLRs were used to investigate the signaling pathway. …”
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5444
Experimental Study on Shear Behavior and Failure Mechanism of Bolted Heterogeneous Rock Joints under Different Anchorage Conditions
Published 2021-01-01“…The shear dislocation between the blocks under shear load results in the interaction between the bolt and surrounding media. …”
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5445
Multitasking: does task-switching add to the effect of dual-tasking on everyday-like driving behavior?
Published 2025-02-01“…The tasks were presented either in separate blocks or in intermixed order (conditions: repetitive vs. switching). …”
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5446
Floods’ Impact on Cities’ Critical Infrastructure: A Case Study on Dubai
Published 2025-01-01“…The main road connecting both sides of the area was completely blocked due to the floods with distant alternative connections while critical infrastructure was mainly concentrated on one of the two sides only. …”
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5447
Soybean cultivars under the foliar application of a compounded biofertilizer in different plant phenological stages and doses
Published 2023-04-01“…This study evaluates the agronomic performance of soybeans with biofertilizer (BF) applications in different soybean phenological stages.Method Experiments were performed in two regions and designed in randomized blocks using a 2×4 factorial scheme (two cultivars and four BF managements). …”
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5448
Insights into the tectonic evolution of the Svecofennian orogeny based on in situ Lu–Hf dating of garnet and apatite from Olkiluoto, southwestern Finland
Published 2025-02-01“…Results reveal detailed temporal constraints for the tectonic evolution that can be linked to major events in adjacent tectonic blocks in both Finland and Sweden during the Svecofennian orogeny. …”
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5449
Effect of hydrophobic corrosion inhibitor on the cement hydration and leaching resistance of shotcrete
Published 2025-07-01“…In the alkaline environment of cement hydration, the hydrolysis products of organic carboxylic acid esters in hydrophobic corrosion inhibitor reacted with calcium ions in hydration products system to generate nano calcium carboxylate particles, which blocking the micro- and nano-scale pores to enhance the compactness and hydrophobicity of shotcrete matrix. …”
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5450
Induction of Apoptosis Coupled to Endoplasmic Reticulum Stress through Regulation of CHOP and JNK in Bone Marrow Mesenchymal Stem Cells from Patients with Systemic Lupus Erythemato...
Published 2015-01-01“…Interestingly, we discovered that 4-phenylbutyric acid (4-PBA), a selective inhibitor of ERS, blocked the apoptosis of BM-MSCs from SLE patients and alleviated the level of Jun N-terminal kinase1/2 (JNK1/2) and CHOP. …”
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5451
Enhanced Proliferation of Porcine Bone Marrow Mesenchymal Stem Cells Induced by Extracellular Calcium is Associated with the Activation of the Calcium-Sensing Receptor and ERK Sign...
Published 2016-01-01“…Moreover, Ca2+o-induced promotion of pBMSCs proliferation, the changes of proliferative genes expression levels, and the activation of ERK1/2 signaling pathway were effectively blocked by U0126, a selective ERK kinase inhibitor. …”
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5452
Expression of genes of cytokines, transcription factors and differentiation antigens in human dendritic cells activated by double-stranded DNA
Published 2017-11-01“…In this work, the expression of cytokines, differentiation antigens and transcription factor genes has been investigated in DCs activated by double-stranded human DNA (i) without any additional factors, (ii) using a lipophilic agent, and (iii) by blocking TLR9 with chloroquine. Evaluation of the DNA effect was carried out after the 6- and 24-hour exposure. …”
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5453
Effects of Stromal Cell-Derived Factor-1α Secreted in Degenerative Intervertebral Disc on Activation and Recruitment of Nucleus Pulposus-Derived Stem Cells
Published 2019-01-01“…After the systemic delivery of exogenous PKH26-labelled NPSCs into the rats in vivo, there was a significant difference in the distribution of the migrated cells between the normal and the degenerative IVDs, which might be caused by the different expression levels of SDF-1α. However, blocking CXC chemokine receptor 4 (CXCR4) with AMD3100 effectively abrogated SDF-1α-stimulated proliferation and migration. …”
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5454
Vimentin-Rab7a Pathway Mediates the Migration of MSCs and Lead to Therapeutic Effects on ARDS
Published 2021-01-01“…Further experiments found that vimentin’s regulation of MSC migration is mainly mediated by Rab7a. Rab7a knockout blocked the migration of MSCs and weakened the therapeutic effect of MSCs in ARDS. …”
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5455
Peripheral Blood-Derived Mesenchymal Stem Cells Modulate Macrophage Plasticity through the IL-10/STAT3 Pathway
Published 2022-01-01“…This effect could also be reversed by blocking the IL-10/STAT3 pathway with Ab9969 and Stattic. …”
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5456
Patient-derived follicular lymphoma spheroids recapitulate lymph node signaling and immune profile uncovering galectin-9 as a novel immunotherapeutic target
Published 2024-05-01“…FL-PDLS allowed uncovering that soluble galectin-9 limits rituximab, rituximab, plus nivolumab/TIM-3 antitumoral activities. Blocking galectin-9 improves rituximab efficacy, highlighting galectin-9 as a novel immunotherapeutic target in FL. …”
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5457
Inhibiting de novo lipogenesis identifies a therapeutic vulnerability in therapy-resistant colorectal cancer
Published 2025-02-01“…The increased expression is mediated by the ETS1-PTPN1-c-Src-CEBPβ pathway. Blocking the conversion of free fatty acids into LDs by treatment with statins or inhibiting lipin1 expression disrupts lipid homeostasis, leading to lipotoxicity and ferroptotic cell death in both DTPs and patient-derived organoids (PDOs) in vitro. …”
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5458
Effect of EGCG–Methacrylate-Functionalized Resin Infiltrant on White Spot Lesions: An In Vitro Study
Published 2024-12-01“…WSLs were created on bovine enamel blocks and treated with I, IE, or IEM. Sound and untreated enamel surfaces were used as controls (C). …”
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5459
The Effect of Contaminants and Temperatures of a High-Palm-Oil Biodiesel Blend on the Lifetime of a Diesel Fuel Filter
Published 2025-01-01“…The results showed that the temperature and cleanliness of the biodiesel had a strong influence on filter blocking. B30 with an ISO cleanliness of 22/21/17 without added standard dust contaminants at 15 °C for 48 h produced larger amounts of deposits compared to B0 with an ISO cleanliness of 16/13/7 with the addition of 1 g of contaminant for the same treatment. …”
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5460
Elucidating the knowledge, attitude, and stigma associated with tuberculosis: a community based descriptive study in Wau and Jur River, South Sudan
Published 2025-02-01“…Methods From March to May 2023, a cross-sectional study was conducted among 352 community members randomly selected from residential blocks. A validated structured questionnaire was used to collect the required data. …”
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