Development of BRS-Pontal beans growing with treated domestic wastewater in protected environment by Raimundo Gomes Filho, Silvaneide Silva, Clayton Carvalho, Gregorio Faccioli, Tatiana Nunes, Simone Feitosa, Leonaria Carvalho

“…Method The experiment was carried out in a protected environment using an experimental design arranged in randomized blocks with a 3 x 4 factorial scheme, in which the bean crop was submitted to different concentrations of 0, 50 and 100% of the treated domestic wastewater and four irrigation levels corresponding to 50%, 75%, 100% and 125% of crop evapotranspiration and four replications. …”
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Ligand-Based Pharmacophore Modeling and Virtual Screening of RAD9 Inhibitors by Nirmal K. Prasad, Vishnupriya Kanakaveti, Siddhartha Eadlapalli, Ramakrishna Vadde, Angamba Potshangbam Meetei, Vaibhav Vindal

“…Overexpression of RAD9 interacts with BCL-2 proteins and blocks the binding sites of BCL-2 family proteins to interact with chemotherapeutic drugs and leads to drug resistance. …”
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Motor Cortex Plasticity during Unilateral Finger Movement with Mirror Visual Feedback by Hatice Kumru, Sergiu Albu, Raul Pelayo, John Rothwell, Eloy Opisso, Daniel Leon, Dolor Soler, Josep Maria Tormos

“…The present study investigated 3 different types of visual feedback (direct, mirrored, and blocked visual feedback: DVF, MVF, and BVF, resp.) on M1 cortex excitability and intracortical inhibition/facilitation at rest and during phasic unimanual motor task in 11 healthy individuals. …”
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A Human/Murine Chimeric Fab Antibody Neutralizes Anthrax Lethal Toxin In Vitro by Guipeng Ding, Ximin Chen, Jin Zhu, Nicholas S. Duesbery, Xunjia Cheng, Brian Cao

“…A murine IgG monoclonal antibody (mAb) against LF with blocking activity (coded LF8) was produced in a previous study. …”
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Research on Influence of Different Simulation Methods of Bypass Flow in Thermal Hydraulic Analysis on Temperature Distribution in HTR-10 by Shiyan Sun, Youjie Zhang, Yanhua Zheng

“…In pebble-bed high temperature gas-cooled reactor, gaps widely exist between graphite blocks and carbon bricks in the reactor core vessel. …”
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Longer-Term Postcure Measurement of Cuspal Deformation Induced by Dimensional Changes in Dental Materials by A. Falsafi, J. D. Oxman, P.-H. Tse, T. T. Ton

“…For shrinkage effects, resulting cusp deformation of aluminum blocks with MOD type cavity, filled with novel filling compositions and commercial cements, has been measured using a bench-top micrometer and a Linear Variable Differential Transformer (LVDT, a displacement transducer) based instrument. …”
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Dietary Supplementation of Astragalus Polysaccharides Enhanced Immune Components and Growth Factors EGF and IGF-1 in Sow Colostrum by Lunbo Tan, Ting Wei, Anwen Yuan, Jun He, Jinhui Liu, Daojun Xu, Qing Yang

“…Dietary supplementation of APS significantly enhanced the presence of IgG, IgM, EGF, and IGF-1 in 0 h-colostrum (P<0.001). The blocking rates of CSFV Ab were increased in samples from APS-supplemented sow when compared to those from the matched samples without APS treatment. …”
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Indoxyl Sulfate Induces Mesangial Cell Proliferation via the Induction of COX-2 by Shuzhen Li, Sijie Cheng, Zhenzhen Sun, Harr-keshauve Mungun, Wei Gong, Jing Yu, Weiwei Xia, Yue Zhang, Songming Huang, Aihua Zhang, Zhanjun Jia

“…Next, we found an inducible inflammation-related enzyme COX-2 was remarkably enhanced by IS, and the inhibition of COX-2 by NS398 significantly blocked IS-induced MC proliferation in line with a blockade of PGE2 production. …”
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Pathological Microenvironment‐Remodeling Nanoparticles to Alleviate Liver Fibrosis: Reversing Hepatocytes‐Hepatic Stellate Cells Malignant Crosstalk by Ling‐Feng Zhang, Wen‐Qi Deng, Xing‐Huan Wang, Qing‐Wen Huang, Su‐Qing Liang, Ze‐Quan Ding, Liang Qi, Yi Wang, Tian‐Jiao Zhou, Lei Xing, Jai‐Woo Lee, Yu‐Kyoung Oh, Hu‐Lin Jiang

“…Herein, a malignant crosstalk‐blocking strategy is prompted to remodel vicious cellular interplay and reverse pathological microenvironment to put an end to liver fibrosis. …”
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The Design and Development of an Atraumatic Soft Robotic Surgical Retractor by Gavril Yong En Tan, Shaun Mahesh Buxani, Benjamin Wee Keong Ang, Chao Yu Chen, Raye Chen Hua Yeow, Hung Leng Kaan

“…The study presents a comprehensive evaluation, including bending angle, blocked force measurements, actuation time efficiency, and a comparative analysis with traditional stainless steel Langenbeck retractors. …”
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Large-scale laboratory investigation of pillar-support interaction by Akash Chaurasia, Gabriel Walton, Sankhaneel Sinha, Timothy J. Batchler, Kieran Moore, Nicholas Vlachopoulos, Bradley Forbes

“…This study used a series of large-scale laboratory compression tests on porous limestone blocks to analyze rock and support behavior at a sufficiently large scale (specimens with edge length of 0.5 m) for incorporation of actual support elements, with consideration of different w/h ratios. …”
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Effect of SIS3 on Extracellular Matrix Remodeling and Repair in a Lipopolysaccharide-Induced ARDS Rat Model by Qiong Liang, Qiqing Lin, Yueyong Li, Weigui Luo, Xia Huang, Yujie Jiang, Chunyan Qin, Jin Nong, Xiang Chen, Suren Rao Sooranna, Liao Pinhu

“…These findings indicate that SIS3, or the blocking of TGF-β/Smad3 pathways, could influence remodeling of the ECM and this may serve as a therapeutic strategy against ARDS.…”
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Antihypertensive effect of sinapine extracted from rapeseed meal in 2K1C hypertensive rats by Gaoyuan Yang, Lin Zhu, Yu Wang, Yang Yu, Xiaoguang Liu, Jingbo Xia, Yunjie Yang, Huiguo Wang, Baomin Feng

“…Furthermore, sinapine effectively inhibited ACE activation, increased NO levels, and blocked L-type calcium channels. Sinapine has an antihypertensive function and achieves this process through multiple targets.…”
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Off-Design Considerations through the Properties of Some Pressure-Ratio Line of Radial Inflow Turbines by N. Binder, X. Carbonneau, P. Chassaing

“…Nevertheless, a simple performance prediction analysis is proposed for blocked mass flow operation.…”
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Dominant Modes of Tropospheric Ozone Variation over East Asia from GOME Observations by Yi Liu, Yuli Zhang, Yong Wang, Chuanxi Liu, Zhaonan Cai, Paul Konopka, Rolf Müller

“…The principal component of EOF1 (PC1) suggested that photochemical ozone production together with Brewer-Dobson circulation and subtropical westerly jet plays important roles in modulating the seasonal variation of the TOVMR; ozone-rich air produced by photochemical processes was transported from the stratosphere to the troposphere by BD circulation and this ozone-rich air was then blocked by the subtropical westerly jet and accumulated north of the jet. …”
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Molecular characterization of siderophore biosynthesis in Paracoccidioides brasiliensis by Marielle Garcia Silva, Juliana Santana de Curcio, Mirelle Garcia Silva-Bailão, Raisa Melo Lima, Mariana Vieira Tomazett, Aparecido Ferreira de Souza, Vanessa Rafaela Milhomem Cruz-Leite, Nicolau Sbaraini, Alexandre Melo Bailão, Fernando Rodrigues, Maristela Pereira, Relber Aguiar Gonçales, Célia Maria de Almeida Soares

“…Furthermore, SidA activity was reduced in the presence of FOB, suggesting that P. brasiliensis blocks siderophores biosynthesis and can explore siderophores in the environment to scavenge iron. …”
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IL-1β Suppresses the Formation of Osteoclasts by Increasing OPG Production via an Autocrine Mechanism Involving Celecoxib-Related Prostaglandins in Chondrocytes by Yusuke Watanabe, Aki Namba, Yukiko Aida, Kazuhiro Honda, Hideki Tanaka, Naoto Suzuki, Hideo Matsumura, Masao Maeno

“…OPG and RANKL expression increased with IL-1β; whereas M-CSF expression decreased. Celecoxib blocked the stimulatory effect of IL-1β. Conditioned medium from IL-1β-treated chondrocytes decreased TRAP staining in RAW264.7 cells. …”
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Antibodies from a Patient with Type 1 Diabetes and Celiac Disease Bind to Macrophages that Express the Scavenger Receptor CD163 by Brigitte Sonier, Alexander Strom, Gen-Sheng Wang, Christopher Patrick, Jennifer A Crookshank, Majid Mojibian, Amanda J MacFarlane, Fraser W Scott

“…Blood monocytes and macrophage-like cells in human duodenum were also labelled with the enriched antibodies. Blocking studies revealed that binding to CD163+ macrophages was not due to cross-reactivity with anti-Glo-3A antibodies, but rather to non-Glo-3A antibodies co-purified during antibody enrichment. …”
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Hydrothermal Synthesis and Characterization of Sodalite from Feldspar Mesawa Minerals by Ida Ifdaliah Amin, Abdul Wahid Wahab, Paulina Taba, Rino R. Mukti, Giovanno Alvin S, Bulkis Musa, Hijrah A. Azis

“…This research proves that the Mesawa feldspar mineral sample contains type 6 secondary building units, the same blocks as zeolite analcime and cancrinite, so it has the potential as an adsorbent for heavy metals and as a catalyst alternative …”
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Disrupting EDEM3‐induced M2‐like macrophage trafficking by glucose restriction overcomes resistance to PD‐1/PD‐L1 blockade by Shaoyong Peng, Minshan Wu, Qian Yan, Gaopo Xu, Yumo Xie, Guannan Tang, Jinxin Lin, Zixu Yuan, Xiaoxia Liang, Ze Yuan, Jingrong Weng, Liangliang Bai, Xiaolin Wang, Huichuan Yu, Meijin Huang, Yanxin Luo, Xiaoxia Liu

“…Conclusions Our study suggests that blocking EDEM3‐induced M2‐like macro phage trafficking by FMD plus 2‐DG is a promising and effective strategy to overcomeresistance to checkpoint blockade therapy offeringhope for improved treatment outcomes. …”
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