Mechanisms by which Human Cells Bypass Damaged Bases during DNA Replication after Ultraviolet Irradiation by James E. Cleaver

“…The mechanism of the secondary bypass is unclear, but a number of experiments suggests roles for excision repair to remove damage ahead of replication forks, hRad6/18 proteolysis to clear the blocked forks, and the Rad17-RFC and 9-1-1 complexes to establish a new replication apparatus. …”
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Evaluation of concordance between measurement techniques using graphical methods and regression models with an application by Doğukan Özen

“…TUNEL (Method 1) and Caspase 3 immunohistochemistry techniques (Method 2) were applied to the sections taken from the blocks of these tissue samples. The apoptotic cells in the tissue samples were counted using both methods. …”
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Research on Flood Impact and River Regime of Skew Bridges Crossing River Bend Based on FVM Method by NIU Jiao, CHENG Jingqing, YAN Xiaoyu, JIA Lei, WANG Zhichao

“…Based on finite volume method (FVM) and two-dimension unstructured grid,taking a skew bridge crossing the river bend as the research object,this paper builds a hydrodynamic model of the upstream and downstream of the bridge,and simulates and analyzes the impact of bridge construction on the upstream and downstream water level,flow velocity and river regime under different frequency floods.The results show that:Due to the water blocking action of the piers,the upstream water level of the bridge increases,the flow velocity between the piers increases,and the flow velocity of water face and back face of the piers decreases.As there is a angle between piers of the skew bridge and the natural river course,the water level on the left bank in the downstream rises and the right bank in the downstream drops.The flow velocity and sediment-carrying capacity on the left bank increases compared to those before the project,while those on the right bank decreases,and the affected area was concentrated in the river section near the bridge location.The river section where the bridge is located is bent.The bridge can play a positive role in preventing the siltation of convex bank (left bank) and the scour of concave bank (right bank) downstream the bridge.The research results can provide reference for the design of skew bridge.…”
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ABOUT DATA MODELING SUBJECT DOMAINS PRACTICE-ORIENTED DIRECTION FOR UNIVERSAL SYSTEM OF STORAGE AND PROCESSING DATA by L. V. Rudikova, E. V. Zhavnerko

“…Offered appropriate data models, considered relationship between them as data processing and data warehouse creation, which can be built on information data storage technology and which has some characteristics as extensible complex subject domain, data integration, which get from any data sources, data time invariance with required temporal marks, relatively high data stability, search necessary compromises in data redundancy, system blocks modularity, flexibility and extensibility of architecture, high requirements to data storage security. …”
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Performance Deterioration of Pitot Tubes Caused by In-Flight Ice Accretion: A Numerical Investigation by Hao Zhang, Rui Zhao, Chih-Yung Wen

“…Under varying inflow conditions and wall temperatures, the calculated ice accretion performance indicates that the ambient temperature has the most significant effect on the icing-induced failure time, leading to an almost exponential growth. Meanwhile, the blocking time is found to be linearly proportional to the increase in wall temperature. …”
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BCL6 (B-cell lymphoma 6) expression in adenomyosis, leiomyomas and normal myometrium. by Loreta Canivilo Salas, Bruna Mielczarski, Raquel Camara Rivero, João Sabino Lahogue da Cunha Filho, Ricardo Francalacci Savaris

“…We analyzed paraffin blocks from total hysterectomies performed between 2009 and 2017, confirming diagnoses through pathological review. …”
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Text analysis of DNS queries for data exfiltration protection of computer networks by Ya. V. Bubnov, N. N. Ivanov

“…The architecture implies creation of response policy zones for blocking of individual requests, classified as malicious.…”
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Enterovesical Fistula: A Rare Complication of Urethral Catheterization by Amr Hawary, Laurence Clarke, Alasdair Taylor, Peter Duffy

“…They include recurrent urinary tract infections, recurrent pyelonephritis, sepsis, urethral stricture, blocked and retained catheters, among many other reported complications. …”
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TSG-6 Downregulates IFN-Alpha and TNF-Alpha Expression by Suppressing IRF7 Phosphorylation in Human Plasmacytoid Dendritic Cells by L. Kui, G. C. Chan, P. P. W. Lee

“…Following recombinant human TSG-6 treatment and CpG-A or R837 stimulation, significant reduction in IFN-α and TNF-α was observed in healthy donors’ pDCs, and the same phenomenon was confirmed in GEN2.2. By CD44 blocking assay, we deduced that the suppressive effect of TSG-6 is mediated by CD44, by reducing IRF-7 phosphorylation. …”
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Intraoperative Imaging of Positron Emission Tomographic Radiotracers Using Cerenkov Luminescence Emissions by Jason P. Holland, Guillaume Normand, Alessandro Ruggiero, Jason S. Lewis, Jan Grimm

“…Competitive inhibition (blocking) studies followed by CLI also confirmed the in vivo immunoreactivity and specificity of 89 Zr-DFO-trastuzumab for HER2/neu . …”
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Application of Distance Learning at Technical Universities by S. A. Kras’ko, L. G. Sergeeva, N. N. Mikhailova

“…The article considers their main blocks such as: instructive, communicative, informational (theoretical and practical parts) and final control. …”
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Evaluation method of snow accretion around train bogie using model vehicle running apparatus by Hajime TAKAMI, Yuto ARAKI

“…Comparison of snow accretion on the end blocking vertical panel downstream of the bogies of an intermediate car between real cars and model running tests confirmed that the general characteristics of the snow distribution adhered on the panel can be reproduced. …”
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Numerical investigation of trihybrid nanofluid heat transfer in a cavity with a hot baffle by Rajab Alsayegh

“…Using numerical simulations and Patankar's blocked-off region method, a parametric study was conducted, varying the Rayleigh number (5000–50,000), nanoparticle volume fraction Φ (0–0.06), obstacle size and aspect ratio (h:w from 0.7 to 9), and Marangoni number (−10,000 to 10,000). …”
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THE ROLE OF NATIONAL SOCIAL STATES FOR PRESERVATION AND PROTECTION OF SOCIAL VALUES IN THE CONTEXT OF NEOLIBERAL GLOBAL ORDER by Domeniko Kvartuč, Valentino Kuzelj

“…Given this, economic inequalities are perpetuated, and the social instruments of national states have been blocked due to networking in the global market that follows the pattern of the neoliberal paradigm. …”
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Assessing structural integrity of non-homogeneous systems by means of Acoustic Emissions and Non-Extensive Statistical Mechanics by Stavros K. Kourkoulis, Ermioni D. Pasiou, Ilias Stavrakas, Dimos Triantis

“…The specimens used for the experiments were marble blocks simulating either fragmented and restored epistyles or mutually interconnected intact epistyles of the Parthenon Temple on the Acropolis of Athens. …”
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Analysis and Application on Controlling Thick Hard Roof Caving with Deep-Hole Position Presplitting Blasting by Baobao Chen, Changyou Liu

“…Based on the instability mechanism, the fracture model for THR was established, including rock blocks articulation and combined cantilever beam, and the limit initial and periodic intervals of THR were determined to be 36.0 m and 8.0 m, respectively. …”
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Experimental Study on the Influence of Borehole Angles on Fracture Grouting in Limestone Aquifers by Jianbo Li, Yanchun Xu

“…The slurry stone body formed through deposition is the key area for blocking water, and the borehole angles are the key to ensure the second gravity deposition. …”
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Slope Reinforcement Mechanism and Stability Analysis of <italic>Ophiopogon bodinieri</italic> Under Rainfall Conditions by GUO Jianjun, ZhangWei, CaoHeng, WuZhenwei

“…According to the results, <italic>O. bodinieri</italic> enhances the integrity of the surface soil and increases the compactness of the soil with the extrusion and anchoring effects of the roots and the spindle-shaped blocks at the end. During rainfall, the root system of <italic>O. bodinieri</italic> can effectively limit the displacement of the slope surface, so that the large displacement area is transferred to the rear of the slope top. …”
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Treatment with the CCR5 antagonist OB-002 reduces lung pathology, but does not prevent disease in a Syrian hamster model of SARS-CoV-2 infection. by Bryce M Warner, Robert Vendramelli, Amrit S Boese, Jonathan Audet, Nikesh Tailor, Courtney Meilleur, Nathan Glowach, Marnie Willman, Thang Truong, Estella Moffat, Kevin Tierney, Beata Kosak, Irfan Dhanidina, Jarret Engstrom, Bozena Korczak, Ian McGowan, Carissa Embury-Hyatt, Darwyn Kobasa

“…A potential drug target is the CCR5-CCL5 axis, and blocking this pathway may protect against severe disease. …”
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Activating the Antitumor Immune Response in Non-Hodgkin Lymphoma Using Immune Checkpoint Inhibitors by Maansi Joshi, Stephen M. Ansell

“…It is increasingly apparent that the immune system plays a significant role in the propagation and survival of malignant cells. Immune checkpoint blocking agents augment cytotoxic activity of the adaptive and innate immune systems and enhance tumor cell killing. …”
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