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  1. 4081

    Anti-Inflammatory Effect of Columbianetin on Lipopolysaccharide-Stimulated Human Peripheral Blood Mononuclear Cells by Junying Lu, Keyong Fang, Shiji Wang, Lingxin Xiong, Chao Zhang, Zhongmin Liu, Xuewa Guan, Ruipeng Zheng, Guoqiang Wang, Jingtong Zheng, Fang Wang

    Published 2018-01-01
    “…Furthermore, the inhibitory effects of CBT on NOD1/NF-κB pathways were blocked by ML130. These findings indicated that CBT inhibits the production of inflammatory cytokines induced by LPS involved in the downregulation of NOD1/NF-κB pathways.…”
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  2. 4082

    Telbivudine Treatment during Late Pregnancy Prevents Mother-to-Child Transmission of Hepatitis B Virus: A Retrospective Study by Mengzhi Cai, Yanli Hao, Jianxin Zhong, Wei Yao, Xia Cao, Guifang Gu, Gang Qin

    Published 2019-01-01
    “…To investigate the efficacy of telbivudine (LdT) in blocking mother-to-child transmission (MTCT) of hepatitis B virus (HBV) during late pregnancy. …”
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    Article
  3. 4083

    miR-7-5p Promotes Hepatic Stellate Cell Activation by Targeting Fibroblast Growth Factor Receptor 4 by Shuxia Tian, Min Chen, Bing Wang, Yonglong Han, Haonan Shang, Junming Chen

    Published 2020-01-01
    “…The miR-7-5p inhibitor blocked the lipopolysaccharide-induced proliferation and activation of LX-2 cells, and FGFR4 overexpression inhibited LX-2 cell proliferation and activation triggered by miR-7-5p. …”
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  4. 4084

    Effects of Land Uses on Soil Quality Indicators: The Case of Geshy Subcatchment, Gojeb River Catchment, Ethiopia by Melku Dagnachew, Awdenegest Moges, Asfaw Kebede Kassa

    Published 2019-01-01
    “…Accordingly, a total of 54 soil samples (three LU types × three slope classes (blocks) × three replications × two soil depths) were collected with an “X” plot design for data analysis. …”
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  5. 4085
  6. 4086

    Implication of IL-17 in Bone Loss and Structural Damage in Inflammatory Rheumatic Diseases by Benoit Le Goff, Béatrice Bouvard, Thierry Lequerre, Eric Lespessailles, Hubert Marotte, Yves-Marie Pers, Bernard Cortet

    Published 2019-01-01
    “…The prevention of structural damage by anti-IL-17A therapies has been demonstrated in several pivotal clinical trials. Overall, blocking the IL-17A pathway seems to have a positive effect on the bone and cartilage damage observed in inflammatory arthritis. …”
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    Article
  7. 4087

    The effect of replacing red algae on histomorphology and enzymes of digestive tract of Nile tilapia, Oreochromis niloticus by Sanaz Kord, Rahim Abdi, Isaac Zamani, Rhima Peyghan

    Published 2024-03-01
    “…After going through the routine steps of tissue preparation, including dehydration with alcohol, clarification with xylol, blocking with paraffin, cutting with a thickness of 4-6 microns with a microtome, and hematoxylin-eosin staining, finally, the evaluation was done with a light microscope. …”
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  8. 4088

    Quality of Life as Medicine: A Pilot Studyof Patients with Chronic Illness and Pain by Soren Ventegodt, Joav Merrick, JØrgen Anderson

    Published 2003-01-01
    “…Consequently, the patients became more present in the body’s blocked-off areas and subjectively healthier. Nineteen persons with chronic illness and pain (fibromyalgia, chronic tiredness, whiplash, mild depression, and problems involving pain in arms and legs including osteoarthritis), and unemployed for 5–7 years attended the course. …”
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  9. 4089

    Assessment of the bypass of obturation materials beyond fractured instruments after using different obturation techniques in simulated curved canals (An in-vitro study). by Ammar Aziz Lateef, Mohammed Rasheed Hameed, Noor Hayder Fadhil, Ahmed Hamid Ali

    Published 2025-01-01
    “…This study evaluated the extent to which obturation materials bypass fractured endodontic instruments positioned in the middle and apical thirds of severely curved simulated root canals using different obturation techniques. Sixty resin blocks with simulated root canals were used, each with a 50° curvature, a 6.5 mm radius of curvature, and a length of 16.5 mm, prepared to an ISO #15 diameter and taper. …”
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  10. 4090

    Research and Development of Civil Engineering Intelligent Structure System by Junkai Xie, Bo Gao, Huamin Cheng

    Published 2021-01-01
    “…The foundation wall with aerated concrete blocks as the wall material can meet the requirements of 50% energy saving for exterior wall buildings with external decoration and internal insulation mortar. …”
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  11. 4091

    The Inhibitory Effects of Alpha 1 Antitrypsin on Endosomal TLR Signaling Pathways by Ahmed S. Elshikha, Georges Abboud, Rigena Avdiaj, Laurence Morel, Sihong Song

    Published 2025-01-01
    “…Specifically, hAAT completely blocked the R848 induction of germinal center T cells (GC T), B cells (GC B), and plasma cells (GC PCs), as well as T follicular T helper cells (T<sub>FH</sub>), which are all critical in lupus development. …”
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  12. 4092

    In Vitro and in Vivo Hypolipidemic Effects of Protein-Polysaccharide Complexes from Three Species of Edible Fungi by GAO Chen, LI Wen, CHEN Wanchao, WU Di, ZHANG Zhong, LIU Peng, XIA Yongjun, YANG Yan

    Published 2024-12-01
    “…Animal experiments showed that they significantly inhibited the increase in body mass, triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C) levels, blocked the swelling of the swelling of hepatocytes, and inhibited hepatic lipid deposition in mice fed a high-fat diet. …”
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  13. 4093

    Transcriptome Analysis of the Effect of Acute Ammonia Stress on <i>Pseudobagrus ussuriensis</i> Liver Tissue by Shun Shi, Xiaohui Sun, Chunnuan Zhang, Chenran Lv, Yajuan Liu, Juan Du, Qian Qi

    Published 2025-01-01
    “…In-depth analysis revealed the stress caused multiple substitutions of SNP sites in pik3ca and kras, blocking the PI3K/Akt signaling pathway to prevent cancer cell proliferation and spread, accelerating the apoptosis of damaged cells. …”
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  14. 4094

    STAT3 Expression and Its Correlation with PD-L1 Expression in Non-Hodgkin’s Lymphoma and Hodgkin’s Lymphoma at Dr. Saiful Anwar Regional Public Hospital in Malang, Indonesian Popul... by Ailen Oktaviana Hambalie, Eviana Norahmawati, Agustina Tri Endharti, Diah Prabawati Retnani, Nayla Rahmadiani

    Published 2024-01-01
    “…Samples were obtained from paraffin blocks of patients with confirmed diagnoses of NHL and HL, and then immunohistochemical staining was carried out with PD-L1 and STAT3 antibodies. …”
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  15. 4095

    Timosin alpha-1 immunomodulating properties by M. V. Mayevskaya

    Published 2009-02-01
    “…Combination of Timosin alpha-1 and interferon-a (IFN-a) induces substantial increase of IL-2 level and blocks elevation of IL-10 level invoked by IFN-a that can be successfully utilized in chronic hepatitis B (CHB) treatment. …”
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  16. 4096

    Interleukin-17 prevents oxidative stress from damaging osteoblast formation by inhibiting autophagic degradation of metallothionein-2 by Xueyan Ling, Cuixia Wang, Qin Feng, Tao Zhang

    Published 2024-06-01
    “…Furthermore, IL-17A-inhibited ROS production were blocked by MT-2 silencing. In conclusion, IL-17A promotes ROS clearance by inhibiting autophagic degradation of MT-2, thereby protecting osteoblast formation from oxidative stress.…”
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  17. 4097

    Identification and functional validation of a new gene conferring resistance to Soybean Mosaic Virus strains SC4 and SC20 in soybean by Muhammad Muzzafar Raza, Huiying Jia, Muhammad Khuram Razzaq, Bowen Li, Kai Li, Junyi Gai

    Published 2025-01-01
    “…Linkage mapping showed two loci for SC4 and SC20 in neighboring single nucleotide polymorphism linkage disequilibrium blocks (SNPLDB) marker regions of 253 kb and 375 kb, respectively, in Kefeng-1. …”
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  18. 4098

    Stability of a Rock Tunnel Passing through Talus-Like Formations: A Case Study in Southwestern China by Shaoqiang Zhang, Wenqiang Li, Jiashan Tan, Bokuan Li, Xiaochang Li, Shuaifeng Wang, Zixin Zhang

    Published 2021-01-01
    “…It mainly passes through talus-like formations comprised of rock blocks of diverse sizes and weak interlayers with clayey soils with different fractions. …”
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  19. 4099

    Single-shot super-resolved fringe projection profilometry (SSSR-FPP): 100,000 frames-per-second 3D imaging with deep learning by Bowen Wang, Wenwu Chen, Jiaming Qian, Shijie Feng, Qian Chen, Chao Zuo

    Published 2025-02-01
    “…To demonstrate the high spatio-temporal resolution of SSSR-FPP, we present 3D videography of several transient scenes, including rotating turbofan blades, exploding building blocks, and the reciprocating motion of a steam engine, etc., which were previously challenging or even impossible to capture with conventional methods. …”
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  20. 4100

    Mathematical modeling of quorum sensing dynamics in batch culture of luminescent bacterium <i>Photobacterium phosphoreum</i> 1889 by S. I. Bartsev, A. B. Sarangova

    Published 2023-12-01
    “…The model contains four blocks describing ecological, energy, quorum and luminescent aspects of bacterial culture growth. …”
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