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4081
Anti-Inflammatory Effect of Columbianetin on Lipopolysaccharide-Stimulated Human Peripheral Blood Mononuclear Cells
Published 2018-01-01“…Furthermore, the inhibitory effects of CBT on NOD1/NF-κB pathways were blocked by ML130. These findings indicated that CBT inhibits the production of inflammatory cytokines induced by LPS involved in the downregulation of NOD1/NF-κB pathways.…”
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4082
Telbivudine Treatment during Late Pregnancy Prevents Mother-to-Child Transmission of Hepatitis B Virus: A Retrospective Study
Published 2019-01-01“…To investigate the efficacy of telbivudine (LdT) in blocking mother-to-child transmission (MTCT) of hepatitis B virus (HBV) during late pregnancy. …”
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4083
miR-7-5p Promotes Hepatic Stellate Cell Activation by Targeting Fibroblast Growth Factor Receptor 4
Published 2020-01-01“…The miR-7-5p inhibitor blocked the lipopolysaccharide-induced proliferation and activation of LX-2 cells, and FGFR4 overexpression inhibited LX-2 cell proliferation and activation triggered by miR-7-5p. …”
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4084
Effects of Land Uses on Soil Quality Indicators: The Case of Geshy Subcatchment, Gojeb River Catchment, Ethiopia
Published 2019-01-01“…Accordingly, a total of 54 soil samples (three LU types × three slope classes (blocks) × three replications × two soil depths) were collected with an “X” plot design for data analysis. …”
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4085
Recovery from Liver Failure and Fibrosis in a Rat Portacaval Anastomosis Model after Neurointermediate Pituitary Lobectomy
Published 2021-01-01“…The success of the AVP deficiency strategy suggests that blocking AVP receptors may be therapeutically useful to treat inflammatory-fibrotic liver diseases.…”
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4086
Implication of IL-17 in Bone Loss and Structural Damage in Inflammatory Rheumatic Diseases
Published 2019-01-01“…The prevention of structural damage by anti-IL-17A therapies has been demonstrated in several pivotal clinical trials. Overall, blocking the IL-17A pathway seems to have a positive effect on the bone and cartilage damage observed in inflammatory arthritis. …”
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4087
The effect of replacing red algae on histomorphology and enzymes of digestive tract of Nile tilapia, Oreochromis niloticus
Published 2024-03-01“…After going through the routine steps of tissue preparation, including dehydration with alcohol, clarification with xylol, blocking with paraffin, cutting with a thickness of 4-6 microns with a microtome, and hematoxylin-eosin staining, finally, the evaluation was done with a light microscope. …”
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4088
Quality of Life as Medicine: A Pilot Studyof Patients with Chronic Illness and Pain
Published 2003-01-01“…Consequently, the patients became more present in the body’s blocked-off areas and subjectively healthier. Nineteen persons with chronic illness and pain (fibromyalgia, chronic tiredness, whiplash, mild depression, and problems involving pain in arms and legs including osteoarthritis), and unemployed for 5–7 years attended the course. …”
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4089
Assessment of the bypass of obturation materials beyond fractured instruments after using different obturation techniques in simulated curved canals (An in-vitro study).
Published 2025-01-01“…This study evaluated the extent to which obturation materials bypass fractured endodontic instruments positioned in the middle and apical thirds of severely curved simulated root canals using different obturation techniques. Sixty resin blocks with simulated root canals were used, each with a 50° curvature, a 6.5 mm radius of curvature, and a length of 16.5 mm, prepared to an ISO #15 diameter and taper. …”
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4090
Research and Development of Civil Engineering Intelligent Structure System
Published 2021-01-01“…The foundation wall with aerated concrete blocks as the wall material can meet the requirements of 50% energy saving for exterior wall buildings with external decoration and internal insulation mortar. …”
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4091
The Inhibitory Effects of Alpha 1 Antitrypsin on Endosomal TLR Signaling Pathways
Published 2025-01-01“…Specifically, hAAT completely blocked the R848 induction of germinal center T cells (GC T), B cells (GC B), and plasma cells (GC PCs), as well as T follicular T helper cells (T<sub>FH</sub>), which are all critical in lupus development. …”
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4092
In Vitro and in Vivo Hypolipidemic Effects of Protein-Polysaccharide Complexes from Three Species of Edible Fungi
Published 2024-12-01“…Animal experiments showed that they significantly inhibited the increase in body mass, triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C) levels, blocked the swelling of the swelling of hepatocytes, and inhibited hepatic lipid deposition in mice fed a high-fat diet. …”
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4093
Transcriptome Analysis of the Effect of Acute Ammonia Stress on <i>Pseudobagrus ussuriensis</i> Liver Tissue
Published 2025-01-01“…In-depth analysis revealed the stress caused multiple substitutions of SNP sites in pik3ca and kras, blocking the PI3K/Akt signaling pathway to prevent cancer cell proliferation and spread, accelerating the apoptosis of damaged cells. …”
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4094
STAT3 Expression and Its Correlation with PD-L1 Expression in Non-Hodgkin’s Lymphoma and Hodgkin’s Lymphoma at Dr. Saiful Anwar Regional Public Hospital in Malang, Indonesian Popul...
Published 2024-01-01“…Samples were obtained from paraffin blocks of patients with confirmed diagnoses of NHL and HL, and then immunohistochemical staining was carried out with PD-L1 and STAT3 antibodies. …”
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4095
Timosin alpha-1 immunomodulating properties
Published 2009-02-01“…Combination of Timosin alpha-1 and interferon-a (IFN-a) induces substantial increase of IL-2 level and blocks elevation of IL-10 level invoked by IFN-a that can be successfully utilized in chronic hepatitis B (CHB) treatment. …”
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4096
Interleukin-17 prevents oxidative stress from damaging osteoblast formation by inhibiting autophagic degradation of metallothionein-2
Published 2024-06-01“…Furthermore, IL-17A-inhibited ROS production were blocked by MT-2 silencing. In conclusion, IL-17A promotes ROS clearance by inhibiting autophagic degradation of MT-2, thereby protecting osteoblast formation from oxidative stress.…”
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4097
Identification and functional validation of a new gene conferring resistance to Soybean Mosaic Virus strains SC4 and SC20 in soybean
Published 2025-01-01“…Linkage mapping showed two loci for SC4 and SC20 in neighboring single nucleotide polymorphism linkage disequilibrium blocks (SNPLDB) marker regions of 253 kb and 375 kb, respectively, in Kefeng-1. …”
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4098
Stability of a Rock Tunnel Passing through Talus-Like Formations: A Case Study in Southwestern China
Published 2021-01-01“…It mainly passes through talus-like formations comprised of rock blocks of diverse sizes and weak interlayers with clayey soils with different fractions. …”
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4099
Single-shot super-resolved fringe projection profilometry (SSSR-FPP): 100,000 frames-per-second 3D imaging with deep learning
Published 2025-02-01“…To demonstrate the high spatio-temporal resolution of SSSR-FPP, we present 3D videography of several transient scenes, including rotating turbofan blades, exploding building blocks, and the reciprocating motion of a steam engine, etc., which were previously challenging or even impossible to capture with conventional methods. …”
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4100
Mathematical modeling of quorum sensing dynamics in batch culture of luminescent bacterium <i>Photobacterium phosphoreum</i> 1889
Published 2023-12-01“…The model contains four blocks describing ecological, energy, quorum and luminescent aspects of bacterial culture growth. …”
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