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3981
Automatic Sleep Stage Classification Based on Convolutional Neural Network and Fine-Grained Segments
Published 2018-01-01“…Next, each segment in this series is individually put into the designed CNN and feature maps are obtained after two blocks of convolution and max-pooling as well as a full-connected operation. …”
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3982
Characteristics of Plasmodium vivax apicomplexan amino acid transporter 8 (PvApiAT8) in the cationic amino acid transport
Published 2025-02-01“…A promising new treatment aimed at targeting P. vivax involves blocking cationic amino acid uptake, which is a biological source of nutrients for the parasite. …”
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3983
Muscarinic cannabinoid suppression of excitation, a novel form of coincidence detection
Published 2025-02-01“…Here we report that coincident activation of muscarinic acetylcholine receptors and elicitation of DSE in autaptic hippocampal neurons results in a substantial (∼40 %) and temporally precise inhibition of excitatory transmission lasting ∼10 minutes. Its induction is blocked by CB1 and muscarinic M3/M5 receptor antagonists and is absent in CB1 receptor knockout neurons. …”
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3984
Higher School Teacher’s Competences and “Electronic” Pedagogical Culture in the Post-Pandemic World
Published 2021-07-01“…This allows us to declare the emergence of a new type of pedagogical culture, namely the “electronic” pedagogical culture of a higher school teacher, which is a natural result of the development of “basic” culture and is characterized by a change in priorities in the structure and in the content of its constituent blocks of competences. The article compares real changes in the structure of a teacher’s personality with forecasts regarding the “competences of the future”, as well as with the “information pedagogical culture”, which is believed to have arisen in the process of information technologies penetration into the educational process. …”
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3985
The impact of intermittent preventive treatment in school aged children with dihydroartemisinin piperaquine and artesunate amodiaquine on IgG response against six blood stage Plasm...
Published 2025-01-01“…Several interventional strategies have been implemented in malaria endemic areas where the burden is high, that include among others, intermittent preventive treatment (IPT), a tactic that blocks transmission and can reduce disease morbidity. …”
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3986
miR-134-3p Regulates Cell Proliferation and Apoptosis by Targeting INHBA via Inhibiting the TGF-β/PI3K/AKT Pathway in Sheep Granulosa Cells
Published 2024-12-01“…Importantly, miR-134-3p overexpression blocked the PI3K/AKT/mTOR axis, whereas its knockdown stimulated it. …”
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3987
Can Soil Compaction Alter Morphophysiological Responses and Soybean Yield under Application of Selective Herbicides?
Published 2023-01-01“…In a greenhouse, the study was carried out in a completely randomized design in a 2 × 8 factorial, with five replications, while in the field, the design used was randomized blocks, with the treatments arranged in split-plot (2 × 8), with six repetitions. …”
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3988
Notch Signaling Pathway Promotes Th17 Cell Differentiation and Participates in Thyroid Autoimmune Injury in Experimental Autoimmune Thyroiditis Mice
Published 2023-01-01“…The degrees of thyroiditis, the proportions of Th17 cells, and the expression of RORγt and IL-17A were significantly decreased in the EAT-B group after blocking the Notch signaling pathway by DAPT, and these parameters were significantly increased in the EAT-A group compared to the control group (all P<0.05). …”
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3989
A Chromosome-Scale Genome of <i>Trametes versicolor</i> and Transcriptome-Based Screening for Light-Induced Genes That Promote Triterpene Biosynthesis
Published 2025-01-01“…Comparative genomic analysis identified 266 syntenic blocks between <i>T. versicolor</i> and <i>Wolfiporia cocos</i>, indicating a conserved evolutionary pattern between the two species. …”
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3990
Microiontophoretic Application of Dynorphin in Dental Pain: Excitatory or Inhibitory Effects
Published 2025-01-01“…The inhibitory effects of dynorphin were blocked by nor-binaltorphimine, a kappa receptor antagonist, whereas the facilitatory effects were inhibited by D,L-2-amino-5-phosphonovaleric acid, an NMDA receptor antagonist.Conclusion: These findings suggest that dynorphin A-induced excitatory responses are mediated by NMDA receptors, whereas its inhibitory responses are mediated through kappa opioid receptors in dental pain. …”
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3991
Impact of glycolysis inhibitor (2-DG) and oxidation and phosphorylation uncoupler (2,4-DNP) on brain metabolites
Published 2018-04-01“…In the present study, we tested the hypothesis of multidirectional changes in metabolism under the impact of the oxidation and phosphorylation uncoupler 2,4-dinitrophenol (2,4-DNP) and under the impact of 2-deoxy-Dglucose (2-DG), blocking the access of glucose to the brain cells. 1H NMR spectroscopy showed that 2-DG leads to the predominance of excitatory (glutamine + glutamate) neurotransmitters over inhibitory ones (gamma-aminobutyric acid), and 2,4 DNP causes opposite effects. …”
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3992
Expression Levels of IL-17A, IL-17F, IL-17RA, and IL-17RC in Prostate Cancer with Taking into Account the Histological Grade according to Gleason Scale in Comparison to Benign Pros...
Published 2020-01-01“…Studies were carried out on archival tissue material in the form of paraffin blocks of 40 men with PCa after radical prostatectomy. …”
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3993
Inhibition of hippocampal interleukin-6 receptor-evoked signalling normalises long-term potentiation in dystrophin-deficient mdx mice
Published 2025-02-01“…In dystrophic mdx mice, exposure to IL-6 suppressed mitochondrial-mediated basal metabolism in CA1, CA3 and DG hippocampal regions. Furthermore, blocking IL-6-mediated signalling by administering neutralising monoclonal IL-6 receptor antibodies intrathecally, normalised LTP in mdx mice. …”
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3994
Enhanced Removal Efficiency of Malachite Green Dye Using Gambir Leaf Extract-Modified NiFe LDH Composites: A Study of Cationic Dye Adsorption
Published 2024-12-01“…The BET analysis indicated a decrease in the surface area of NiFe-UG LDH compared to that of NiFe LDH, suggesting that active compounds from the gambier leaf extract effectively coated the LDH surface and blocked its pores. During malachite green (MG) adsorption, NiFe-UG demonstrated faster adsorption kinetics and a higher adsorption efficiency, reaching 96.420% compared to 92.085% for NiFe LDH. …”
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3995
Nitrogenated Fertilization In Pasture Brachiaria Brizantha Cv. Marandu Via Organic Compounds
Published 2024-04-01“…The experimental design was randomized blocks in a 4 x 2 factorial scheme. The treatments consisted of control with 0 kg/ha of N, 3 treatments with application of bovine liquid manure and 3 treatments with organomineral fertilizer in the dosages of 60, 120 and 180 kg/ha of N. …”
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3996
Hysterosalpingography Findings and Jimah Ratio of the Uterine Cavity in Women with Infertility in Central Region, Ghana
Published 2020-01-01“…Abnormalities were higher in the fallopian tubes than the uterus, while capacious uterine cavity, uterine fibroid, and bilaterally blocked tubes were the top three abnormalities found.…”
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3997
Callus Formation in Fractured Femur of Rats Treated with Injection of Human Umbilical Cord Mesenchymal Stem Cell-Conditioned Medium
Published 2021-01-01“…Histologic preparations were done by the paraffin method, by cutting the tissue blocks into 5 μm thickness and then staining with Mallory aniline blue staining. …”
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3998
The Effect of Sandblast and Plasma Surface Treatment of Titanium Abutment on Tensile Bond Strength with Ultra-translucent Zirconia Crown: A Comparative Study
Published 2024-12-01“…Materials and methods: Forty samples of implant analog and prefabricated titanium implant abutment of Dentium system with diameter (3.5mm) and height (5.5mm) were embedded vertically in auto-polymerizing acrylic resin blocks, were divided into five groups according to type of crown and abutment surface treatment (10 samples for each group) : Group I titanium abutments and zirconia crowns without any surface treatment, Group II sandblast treated abutments, Group III plasma surface treatment for both titanium abutments, Group IV combine sandblast and plasma treated titanium abutments. …”
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3999
Digging for clues: Stick tools used for honey digging in a second community of ‘forest fragment chimpanzees’ outside the Budongo and Bugoma Forests, Uganda
Published 2020-07-01“…This study also underscores the importance of considering populations surviving in degraded human-modified habitats outside Uganda’s main forest blocks, such as the Mairirwe and Bulindi communities, in regional models to explain variation in chimpanzee tool use.…”
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4000
Efficient Generative-Adversarial U-Net for Multi-Organ Medical Image Segmentation
Published 2025-01-01“…Additionally, we have integrated Efficient Mapping Convolutional Blocks (EMCB) into the feature-learning process, allowing for the extraction of multi-scale spatial information and the adjustment of feature map channels through optimized weight values. …”
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