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3921
Soybean cultivars under the foliar application of a compounded biofertilizer in different plant phenological stages and doses
Published 2023-04-01“…This study evaluates the agronomic performance of soybeans with biofertilizer (BF) applications in different soybean phenological stages.Method Experiments were performed in two regions and designed in randomized blocks using a 2×4 factorial scheme (two cultivars and four BF managements). …”
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3922
Insights into the tectonic evolution of the Svecofennian orogeny based on in situ Lu–Hf dating of garnet and apatite from Olkiluoto, southwestern Finland
Published 2025-02-01“…Results reveal detailed temporal constraints for the tectonic evolution that can be linked to major events in adjacent tectonic blocks in both Finland and Sweden during the Svecofennian orogeny. …”
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3923
Effect of hydrophobic corrosion inhibitor on the cement hydration and leaching resistance of shotcrete
Published 2025-07-01“…In the alkaline environment of cement hydration, the hydrolysis products of organic carboxylic acid esters in hydrophobic corrosion inhibitor reacted with calcium ions in hydration products system to generate nano calcium carboxylate particles, which blocking the micro- and nano-scale pores to enhance the compactness and hydrophobicity of shotcrete matrix. …”
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3924
Induction of Apoptosis Coupled to Endoplasmic Reticulum Stress through Regulation of CHOP and JNK in Bone Marrow Mesenchymal Stem Cells from Patients with Systemic Lupus Erythemato...
Published 2015-01-01“…Interestingly, we discovered that 4-phenylbutyric acid (4-PBA), a selective inhibitor of ERS, blocked the apoptosis of BM-MSCs from SLE patients and alleviated the level of Jun N-terminal kinase1/2 (JNK1/2) and CHOP. …”
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3925
Enhanced Proliferation of Porcine Bone Marrow Mesenchymal Stem Cells Induced by Extracellular Calcium is Associated with the Activation of the Calcium-Sensing Receptor and ERK Sign...
Published 2016-01-01“…Moreover, Ca2+o-induced promotion of pBMSCs proliferation, the changes of proliferative genes expression levels, and the activation of ERK1/2 signaling pathway were effectively blocked by U0126, a selective ERK kinase inhibitor. …”
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3926
Expression of genes of cytokines, transcription factors and differentiation antigens in human dendritic cells activated by double-stranded DNA
Published 2017-11-01“…In this work, the expression of cytokines, differentiation antigens and transcription factor genes has been investigated in DCs activated by double-stranded human DNA (i) without any additional factors, (ii) using a lipophilic agent, and (iii) by blocking TLR9 with chloroquine. Evaluation of the DNA effect was carried out after the 6- and 24-hour exposure. …”
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3927
Effects of Stromal Cell-Derived Factor-1α Secreted in Degenerative Intervertebral Disc on Activation and Recruitment of Nucleus Pulposus-Derived Stem Cells
Published 2019-01-01“…After the systemic delivery of exogenous PKH26-labelled NPSCs into the rats in vivo, there was a significant difference in the distribution of the migrated cells between the normal and the degenerative IVDs, which might be caused by the different expression levels of SDF-1α. However, blocking CXC chemokine receptor 4 (CXCR4) with AMD3100 effectively abrogated SDF-1α-stimulated proliferation and migration. …”
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3928
Vimentin-Rab7a Pathway Mediates the Migration of MSCs and Lead to Therapeutic Effects on ARDS
Published 2021-01-01“…Further experiments found that vimentin’s regulation of MSC migration is mainly mediated by Rab7a. Rab7a knockout blocked the migration of MSCs and weakened the therapeutic effect of MSCs in ARDS. …”
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3929
Peripheral Blood-Derived Mesenchymal Stem Cells Modulate Macrophage Plasticity through the IL-10/STAT3 Pathway
Published 2022-01-01“…This effect could also be reversed by blocking the IL-10/STAT3 pathway with Ab9969 and Stattic. …”
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3930
Patient-derived follicular lymphoma spheroids recapitulate lymph node signaling and immune profile uncovering galectin-9 as a novel immunotherapeutic target
Published 2024-05-01“…FL-PDLS allowed uncovering that soluble galectin-9 limits rituximab, rituximab, plus nivolumab/TIM-3 antitumoral activities. Blocking galectin-9 improves rituximab efficacy, highlighting galectin-9 as a novel immunotherapeutic target in FL. …”
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3931
Effect of EGCG–Methacrylate-Functionalized Resin Infiltrant on White Spot Lesions: An In Vitro Study
Published 2024-12-01“…WSLs were created on bovine enamel blocks and treated with I, IE, or IEM. Sound and untreated enamel surfaces were used as controls (C). …”
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3932
Elucidating the knowledge, attitude, and stigma associated with tuberculosis: a community based descriptive study in Wau and Jur River, South Sudan
Published 2025-02-01“…Methods From March to May 2023, a cross-sectional study was conducted among 352 community members randomly selected from residential blocks. A validated structured questionnaire was used to collect the required data. …”
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3933
Effectively alleviate rheumatoid arthritis via maintaining redox balance, inducing macrophage repolarization and restoring homeostasis of fibroblast-like synoviocytes by metformin-...
Published 2025-01-01“…Mechanistically, MCDs restored the homeostasis of FLSs while reducing the level of synovial inflammation by blocking IL-6/gp130 signaling pathway. Combined with preferable biocompatibility, MCDs offer a prospective treatment approach for RA.…”
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3934
Optimizing water resource management in tropical drought-prone regions through hybrid MCDM techniques: A water-stress mapping approach
Published 2025-02-01“…Though the entire region experiences water-stress, the central part and some portions of the northeastern community development blocks exhibit higher intensity. Our study advances the ability of water-stress area identification, applying integrated methods and comprehensive geospatial datasets in a water-scarce region.…”
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3935
Insulin-Like Growth Factor I Prevents Cellular Aging via Activation of Mitophagy
Published 2020-01-01“…SiRNA-induced inhibition of either Nrf2 or Sirt3 blocked IGF-1-induced upregulation of mitophagy, suggesting that the Nrf2/Sirt3 pathway was required for IGF-1’s effect on mitophagy. …”
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3936
Selenoprotein S Attenuates Tumor Necrosis Factor-α-Induced Dysfunction in Endothelial Cells
Published 2018-01-01“…Furthermore, SelS overexpression blocks the TNF-α-induced adhesion of THP-1 cells to HUVECs and inhibits the increase in intercellular adhesion molecule-1 and vascular cell adhesion molecule-1. …”
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3937
The Role of Lactobacillus reuteri DSMZ17648 for Helicobacter pylori eradication therapy (Review of literature and advisory council resolution, February 28, 2018)
Published 2018-08-01“…It was revealed that lyophilizate of this strain (PylopassTM) blocks adhesion of H. pylori to epithelial cells as well. …”
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3938
GEN-27, a Newly Synthetic Isoflavonoid, Inhibits the Proliferation of Colon Cancer Cells in Inflammation Microenvironment by Suppressing NF-κB Pathway
Published 2016-01-01“…The HCT116 cell proliferation elicited by THP-1-conditioned medium could be blocked by the interleukin-1 receptor antagonist (IL-1RA). …”
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3939
Organic Light-Emitting Diode with Color Tunable between Bluish-White Daylight and Orange-White Dusk Hue
Published 2014-01-01“…This also explains why the incorporation of an extra hole modulation layer with a 0.7 eV barrier did not help extend the desirable color-temperature span since excessive holes may be blocked.…”
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3940
A pilot randomized controlled study of integrated kidney palliative care and chronic kidney disease care implemented in a safety-net hospital: Protocol for a pilot study of feasibi...
Published 2025-04-01“…Participants will be randomized in permuted blocks of two or four to either the intervention group, who will receive monthly ambulatory care visits for six months with a palliative care provider trained in kidney palliative care, or to usual nephrology care. …”
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