Hydrogen-bonded macrocycle-mediated dimerization for orthogonal supramolecular polymerization by Wentao Yu, Zhiyao Yang, Chengkan Yu, Xiaowei Li, Lihua Yuan

“…Establishing this new dimerization motif with shape-persistent H-bonded macrocycles widens the scope of noncovalent building blocks for supramolecular polymers and augurs well for the future development of functional materials.…”
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A Lectin from Dioclea violacea Interacts with Midgut Surface of Lutzomyia migonei, Unlike Its Homologues, Cratylia floribunda Lectin and Canavalia gladiata Lectin by Juliana Montezuma Barbosa Monteiro Tínel, Melina Fechine Costa Benevides, Mércia Sindeaux Frutuoso, Camila Farias Rocha, Francisco Vassiliepe Sousa Arruda, Mayron Alves Vasconcelos, Francisco Nascimento Pereira-Junior, João Batista Cajazeiras, Kyria Santiago do Nascimento, Jorge Luiz Martins, Edson Holanda Teixeira, Benildo Sousa Cavada, Ricardo Pires dos Santos, Margarida Maria Lima Pompeu

“…Furthermore, when DVL was blocked with D-mannose the interaction was inhibited. …”
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Semantic-Assisted LIDAR Tightly Coupled SLAM for Dynamic Environments by Peng Liu, Yuxuan Bi, Jialin Shi, Tianyi Zhang, Caixia Wang

“…This enables the segmentation of static and dynamic points while eliminating both stationary dynamic objects and moving environmental blocking objects. Additionally, in point cloud feature extraction and matching processes, we incorporate constraint conditions based on semantic information to enhance accuracy and improve pose estimation precision. …”
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HOXB8 mediates resistance to cetuximab in colorectal cancer cells through activation of the STAT3 pathway by Yunan Liang, Han Lin, Zongsheng Jiang, Qi Zhao, Ri Cui, Shaotang Li

“…By comparing drug-sensitive cell lines (SW48) with drug-resistant cell lines (HCT116, CACO2), we discovered that HOXB8 was substantially expressed in cetuximab-resistant cell lines, and furthermore, in drug-resistant cell lines (HCT116, CACO2), HOXB8 knockdown increased the cytotoxicity of cetuximab via blocking the signal transducer and activator of transcription 3 (STAT3) signaling pathway. …”
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MODELING OF THE ZONES OF INFLUENCE OF GAS WELLS AT A DEPLETED RESERVOIR by Ioan Alexandru Stoica, Lazăr Avram, Bogdan Simescu, Mihaela Helstern

“…This discretization was achieved through the system of grid blocks, for which the average properties (temperature, pressure, permeability, etc.) and connectivity between them were modeled through the flow coefficients. …”
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Role of periodontal ligament fibroblasts in periodontitis: pathological mechanisms and therapeutic potential by Yijie Huang, Ying Tang, Ruiqi Zhang, Xiao Wu, Li Yan, Xiling Chen, Qianqi Wu, Yiyan Chen, Yingtao Lv, Yuan Su

“…Additionally, this paper summarizes strategies for targeting PDLFs to treat periodontitis, involving blocking multiple stages of the inflammatory response induced by PDLFs and promoting the multidirectional transdifferentiation of PDLFs. …”
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In silico data mining of large-scale databases for the virtual screening of human interleukin-2 inhibitors by Halim Sobia Ahsan, Zaheer-Ul-Haq, Khan Ajmal, Al-Rawahi Ahmed, Al-Harrasi Ahmed

“…T cells activation can be suppressed either by preventing IL-2 production or blocking the IL-2 interaction with its receptor. Hence, IL-2 is now emerging as a target for novel therapeutic approaches in several autoimmune disorders. …”
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Engineering amphiphilic alkenyl lipids for self-assembly in functional hybrid nanostructures by Raúl Gimeno-Ferrero, Victoria Valdivia, Inmaculada Fernández, María Luisa García-Martín, Manuel Pernia Leal

“…A promising approach to overcoming these challenges is the self-assembly of surfactant-based building blocks into well-ordered hybrid nanostructures. In this study, we explore the relationship between structure and self-assembly in novel low molecular weight amphiphilic molecules to produce stable and biocompatible hybrid nanostructures. …”
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Low-Bit Rate Feedback Strategies for Iterative IA-Precoded MIMO-OFDM-Based Systems by Sara Teodoro, Adão Silva, Rui Dinis, Atílio Gameiro

“…With the proposed strategies, we only need to send part of the CSI information, and this can even be sent only once for a set of data blocks transmitted over time-varying channels. These strategies are applied to iterative MMSE-based IA techniques for the downlink of broadband wireless OFDM systems with limited feedback. …”
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Unlocking the potential of azide-phosphine Staudinger reaction for the synthesis of poly(arylene iminophosphorane)s and materials therefrom by Tomaž Kotnik, Antoine Debuigne, Julien De Winter, Matej Huš, Albin Pintar, Sebastijan Kovačič

“…Abstract Iminophosphoranes with the general formula (R3P═NR′) have great potential in synthetic chemistry as valuable precursors/intermediates in organic synthesis or as building blocks for various organic compounds. However, the synthetic approaches and conditions to prepare iminophosphoranes are still poorly understood, limiting the utility of this chemistry for organic materials. …”
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Biophysical Insights into Cancer Transformation and Treatment by Jiří Pokorný, Alberto Foletti, Jitka Kobilková, Anna Jandová, Jan Vrba, Jan Vrba, Martina Nedbalová, Aleš Čoček, Andrea Danani, Jack A. Tuszyński

“…A therapeutic strategy of targeting dysfunctional mitochondria for restoration of their physiological functions makes it possible to switch on the natural apoptotic pathway blocked in cancer transformed cells. Experience with dichloroacetate in cancer treatment and reestablishment of the healthy state may help in the development of novel effective drugs aimed at the mitochondrial function.…”
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Induced Abortion: Risk Factors for Adolescent Female Students, a Brazilian Study by Divanise S. Correia, Jairo C. Cavalcante, Eulàlia M. C. Maia

“…Data were obtained through a semi-structured questionnaire divided into three basic blocks of data: sociodemographic, sexual life, and pregnancy/abortion. …”
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Development of BRS-Pontal beans growing with treated domestic wastewater in protected environment by Raimundo Gomes Filho, Silvaneide Silva, Clayton Carvalho, Gregorio Faccioli, Tatiana Nunes, Simone Feitosa, Leonaria Carvalho

“…Method The experiment was carried out in a protected environment using an experimental design arranged in randomized blocks with a 3 x 4 factorial scheme, in which the bean crop was submitted to different concentrations of 0, 50 and 100% of the treated domestic wastewater and four irrigation levels corresponding to 50%, 75%, 100% and 125% of crop evapotranspiration and four replications. …”
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Ligand-Based Pharmacophore Modeling and Virtual Screening of RAD9 Inhibitors by Nirmal K. Prasad, Vishnupriya Kanakaveti, Siddhartha Eadlapalli, Ramakrishna Vadde, Angamba Potshangbam Meetei, Vaibhav Vindal

“…Overexpression of RAD9 interacts with BCL-2 proteins and blocks the binding sites of BCL-2 family proteins to interact with chemotherapeutic drugs and leads to drug resistance. …”
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Motor Cortex Plasticity during Unilateral Finger Movement with Mirror Visual Feedback by Hatice Kumru, Sergiu Albu, Raul Pelayo, John Rothwell, Eloy Opisso, Daniel Leon, Dolor Soler, Josep Maria Tormos

“…The present study investigated 3 different types of visual feedback (direct, mirrored, and blocked visual feedback: DVF, MVF, and BVF, resp.) on M1 cortex excitability and intracortical inhibition/facilitation at rest and during phasic unimanual motor task in 11 healthy individuals. …”
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A Human/Murine Chimeric Fab Antibody Neutralizes Anthrax Lethal Toxin In Vitro by Guipeng Ding, Ximin Chen, Jin Zhu, Nicholas S. Duesbery, Xunjia Cheng, Brian Cao

“…A murine IgG monoclonal antibody (mAb) against LF with blocking activity (coded LF8) was produced in a previous study. …”
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Research on Influence of Different Simulation Methods of Bypass Flow in Thermal Hydraulic Analysis on Temperature Distribution in HTR-10 by Shiyan Sun, Youjie Zhang, Yanhua Zheng

“…In pebble-bed high temperature gas-cooled reactor, gaps widely exist between graphite blocks and carbon bricks in the reactor core vessel. …”
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Longer-Term Postcure Measurement of Cuspal Deformation Induced by Dimensional Changes in Dental Materials by A. Falsafi, J. D. Oxman, P.-H. Tse, T. T. Ton

“…For shrinkage effects, resulting cusp deformation of aluminum blocks with MOD type cavity, filled with novel filling compositions and commercial cements, has been measured using a bench-top micrometer and a Linear Variable Differential Transformer (LVDT, a displacement transducer) based instrument. …”
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Dietary Supplementation of Astragalus Polysaccharides Enhanced Immune Components and Growth Factors EGF and IGF-1 in Sow Colostrum by Lunbo Tan, Ting Wei, Anwen Yuan, Jun He, Jinhui Liu, Daojun Xu, Qing Yang

“…Dietary supplementation of APS significantly enhanced the presence of IgG, IgM, EGF, and IGF-1 in 0 h-colostrum (P<0.001). The blocking rates of CSFV Ab were increased in samples from APS-supplemented sow when compared to those from the matched samples without APS treatment. …”
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Indoxyl Sulfate Induces Mesangial Cell Proliferation via the Induction of COX-2 by Shuzhen Li, Sijie Cheng, Zhenzhen Sun, Harr-keshauve Mungun, Wei Gong, Jing Yu, Weiwei Xia, Yue Zhang, Songming Huang, Aihua Zhang, Zhanjun Jia

“…Next, we found an inducible inflammation-related enzyme COX-2 was remarkably enhanced by IS, and the inhibition of COX-2 by NS398 significantly blocked IS-induced MC proliferation in line with a blockade of PGE2 production. …”
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