Acetylcholinesterase Inhibitors Assay Using Colorimetric pH Sensitive Strips and Image Analysis by a Smartphone by Adam Kostelnik, Alexander Cegan, Miroslav Pohanka

“…Smartphone served as a tool for measurement of indicator color change from red to orange while inhibitors blocked this process. AChE inhibitors were measured with limits of detection, 149 nM and 22.3 nM for galanthamine and donepezil, respectively. …”
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An Improved Method for Stochastic Nonlinear System’s Identification Using Fuzzy-Type Output-Error Autoregressive Hammerstein–Wiener Model Based on Gradient Algorithm, Multi-Innovat... by Donia Ben Halima Abid, Saif Eddine Abouda, Hanane Medhaffar, Mohamed Chtourou

“…Two fuzzy systems are suggested for the identification of the input and output nonlinear blocks of a proposed model from given input-output data measurements. …”
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MSSA: multi-stage semantic-aware neural network for binary code similarity detection by Bangrui Wan, Jianjun Zhou, Ying Wang, Feng Chen, Ying Qian

“…It effectively integrates the semantic and structural information of assembly instructions within and between basic blocks, and across the entire function through four semantic-aware neural networks, achieving deep understanding of binary code semantics. …”
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Immunotherapy of Ovarian Cancer: The Role of Checkpoint Inhibitors by Francesca De Felice, Claudia Marchetti, Innocenza Palaia, Daniela Musio, Ludovico Muzii, Vincenzo Tombolini, Pierluigi Benedetti Panici

“…Recently, it has emerged that powerful immunologic effector cells may be blocked by inhibitory regulatory pathways controlled by specific molecules often called “immune checkpoints,” which turn off the immune system. …”
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“Brick‐Mortar‐Binder” Design toward Highly Elastic, Hydrophobic, and Flame‐Retardant Thermal Insulator by Shanying Sui, Huafeng Quan, Jingxing Wang, Yufang Lu, Yufan Yang, Yuhan Sheng, Zhifang Sun, Yi Zhang

“…Owing to the distinct building blocks and organized structure, as‐prepared LCS hybrid aerogel exhibits impressive mechanical elasticity, cycling stability at an extremely low temperature (‐196 °C), hydrophobicity, and flame‐retardancy (LOI = 44.6%, UL‐94: V‐0). …”
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Hydrogen Peroxide Is Involved in Salicylic Acid-Elicited Rosmarinic Acid Production in Salvia miltiorrhiza Cell Cultures by Wenfang Hao, Hongbo Guo, Jingyi Zhang, Gege Hu, Yaqin Yao, Juane Dong

“…If H2O2 production was inhibited by NADPH oxidase inhibitor (IMD) or scavenged by quencher (DMTU), RA accumulation would be blocked. These results indicated that H2O2 is secondary messenger for signal transduction, which can be induced by SA, significantly and promotes RA accumulation.…”
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Mechanisms and Mediators of Inflammation: Potential Models for Skin Rejection and Targeted Therapy in Vascularized Composite Allotransplantation by Theresa Hautz, Dolores Wolfram, Johanna Grahammer, Ravi Starzl, Christoph Krapf, Johann Pratschke, W. P. Andrew Lee, Gerald Brandacher, Stefan Schneeberger

“…T cells are key players in skin rejection and are recruited to the skin via activation of adhesion molecules, cytokines, and chemokines. Blocking these molecules has not only shown success in the treatment of inflammatory dermatoses, but also prolonged graft survival in various models of solid organ transplantation. …”
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Metal‐coordinated amino acid/peptide/protein‐based supramolecular self‐assembled nanomaterials for anticancer applications by Maryam Shabbir, Atia Atiq, Jiahua Wang, Maria Atiq, Nyla Saeed, Ibrahim Yildiz, Xuehai Yan, Ruirui Xing, Manzar Abbas

“…We discussed the role of functional groups anchored in building blocks for coordination interactions, and subsequently, the types of interactions were examined from a structure‒function perspective. …”
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New Possibilities for the Treatment of Crohn’s Disease by Z. A. Mamieva, E. A. Poluektova, O. S. Shifrin

“…The drug interrupts the cascade of humoral and cellular reactions leading to transmural inflammation of the intestinal wall by blocking the interaction of the p40 subunit with the IL-12Rβ1 chain on the surface of T-lymphocytes and NK cells. …”
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Analysis of CaF2 Precipitation Process in the Selected Static Mixers by Piotr Maria Synowiec, Magdalena Stec

“…The Kenics and Koflo types have been chosen as their inner shapes convenient for the realization of continuous precipitation processes as incrustation phenomenon and dangerousness of flow blocking are not as high as in other solutions. The main tasks were focused on the recognition of the precipitation kinetics (to get the knowledge of the relative supersaturation, nucleation sources, and mechanisms controlling the crystal growth), determination of conversion efficiency of the chemical reaction by which CaF2 is precipitated, the fluid dynamic conditions on crystal size distribution (CSD), and the identification of particles’ destruction sources as well. …”
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Manufacturing of Ecofriendly Bricks Using Microdust Cotton Waste by Mebrahtom Teklehaimanot, Haregeweyni Hailay, Tamrat Tesfaye

“…The results also show that usage of cotton microdust with different mixing ratios for bricks will give light-weight composite, and brick could be an economical alternative to be used for partition of board concrete blocks and sound barrier panels.…”
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Human Mast Cells (HMC-1 5C6) Enhance Interleukin-6 Production by Quiescent and Lipopolysaccharide-Stimulated Human Coronary Artery Endothelial Cells by Damandeep S. Walia, Mukut Sharma, Vineesh V. Raveendran, Jianping Zhou, Ram Sharma, Daniel J. Stechschulte, Kottarappat N. Dileepan

“…Furthermore, mast cell-derived histamine and proteases accounted for the direct and synergistic effect of mast cells on IL-6 production that was completely blocked by the combination of histamine receptor-1 antagonist and protease inhibitors. …”
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Nutritional properties of Europen eel (Anguilla anguilla) bone peptide-calcium and its apoptosis effect on Caco-2 cells by Hui Teng, Yuewei Qian, Xiaoyun Fan, Hui Cao, Yuting Tian, Lei Chen

“…Western blot analysis revealed that the EBPC-Ca induced apoptosis may be the result of a blocked autophagy flux through mitochondrial-dependent pathway. …”
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Sea Ice Modulates Air–Sea Methane Flux in the Southern Ocean by Gong Zhang, Qinghua Yang, Bo Han, John Prytherch, Brett F. Thornton, Dake Chen

“…The CH4 fluxes are weak in regions of high sea ice concentration (>50%) due to the blocking effect of sea ice. We estimate that the uptake of CH4 during one summer month in the study region offsets 1.2%–2.6% of annual global oceanic CH4 emissions. …”
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A Companding Technique to Reduce Peak-to-Average Ratio in Discrete Multitone Wireline Receivers by Miad Laghaei, Hossein Shakiba, Ali Sheikholeslami

“…This work proposes a novel companding solution in the design of the Continuous Time Linear Equalizer (CTLE) alongside nonlinear blocks to reduce Peak to Average Power Ratio (PAPR), therefore improving the overall link performance. …”
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Neutrophil Extracellular Traps (NETs) and Damage-Associated Molecular Patterns (DAMPs): Two Potential Targets for COVID-19 Treatment by Sebastiano Cicco, Gerolamo Cicco, Vito Racanelli, Angelo Vacca

“…The increase in HMGB1 and NETosis could lead to sustained inflammation due to SARS-CoV-2 infection. Therefore, blocking these molecules might be useful in COVID-19 treatment and should be further studied in the context of targeted therapy.…”
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Network pharmacology study on the mechanism of berberine in Alzheimer’s disease model by Yaoyi Zhang, Shuai Lv, Pinyuan Huang, Lingmin Xiao, Nan Lin, En Huang

“…Through a network pharmacology study, this study supported that BBR played a protective role in the AD mice model via blocking APP processing and amyloid plaque formation. …”
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Brown rice: a missing nutrient-rich health food by Xiuxiu Wu, Tianyi Guo, Feijun Luo, Qinlu Lin

“…Underlying mechanisms have also been analyzed, which include regulating lipid synthesis and metabolism, improving insulin levels and increasing glucose metabolism, anti-oxidation, promoting the immune system, transcription and non-transcriptional regulation, blocking cell cycle, thereby improving disease symptoms and reducing its recurrence rate. …”
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Synthesis and crystal structures of 4,4′-methylenebis(2,6-diethylaniline) and 4,4′-methylenebis(3-chloro-2,6-diethylaniline) by Daniil E. Smirnov, Oleg S. Morozov, Ekaterina S. Afanasyeva, Viktor V. Avdeev

“…The title compounds 4,4′-methylenebis(2,6-diethylaniline) (C21H30N2, 1) and 4,4′-methylenebis(3-chloro-2,6-diethylaniline) (C21H28Cl2N2, 2) are of significant interest as curing agents for a wide range of resins and as building blocks for sterically demanding compounds in the synthesis of ligands for catalysis. …”
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Inhibition mechanism of self-assembled epoxy-silane/dithiol film on copper corrosion by Chen Sang, Juan Qiu, Boyu Yuan, Kaiyu Zhang, Nan Huang, Qinghong Wang, Houyi Ma, Liang Li, Chao Wang

“…The CuCl interlayer in the modified film blocked its micropores, inhibiting the copper corrosion. …”
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