Anatomical and Functional Outcomes of Vitrectomy with/without Intravitreal Methotrexate Infusion for Management of Proliferative Vitreoretinopathy Secondary to Rhegmatogenous Retin... by Samir El Baha, Mahmoud Leila, Ahmed Amr, Mohamed M. A. Lolah

“…Methotrexate as an adjuvant therapy blocks essential drivers in the pathogenetic cascade leading to PVR. …”
Get full text

La transformation de l’ancien centre de détention secrète de Derb Moulay Cherif en musée des « années de plomb » (Casablanca, Maroc) by Anissa Habane

“…The absence of a possible investment inside the former CDS-DMC, the actions were carried out exclusively in the public space, and in an ephemeral and modest way. The third is blocked by the inability to make use of the building itself has prevented it from being turned into a museum for the time being, to preserve memory and educate future generations. …”
Get full text

L’emploi antique des géomatériaux à Reims/Durocortorum by Gilles Fronteau, Sébastien Laratte, Alain Devos, Claire Pichard

“…The Mars Gate example illustrates this use of large blocks of Lutetian limestone, sourced from a distant area in the region. …”
Get full text

Slow Motion and Zoom in HD Digital Videos Using Fractals by Maurizio Murroni, Cristian Perra, Daniele D. Giusto

“…Mainly, interpolation is done either by linear or cubic spline functions or by motion estimation/compensation which both can be applied pixel by pixel, or by partitioning frames into blocks. Purpose of this paper is to present an alternative technique combining fractals theory and wavelet decomposition to achieve spatial zoom and slow motion replay of HD digital color video sequences. …”
Get full text

Establishment of a Rapid and Convenient Fluoroimmunoassay Platform Using Antibodies Against PDL1 and HER2 by Ji Eun Choi, Hanool Yun, Hee-Jin Jeong

“…We optimized key steps in the FLISA process, including antigen immobilization, blocking, and antibody reaction, reading the assay time to 3 h—significantly faster compared to the 23 h duration of usual FLISA. …”
Get full text

Evaluation of Pigeon Pea Lines for Biological Soil Decompaction by Rodolfo Godoy, Osny Oliveira Santos Bacchi, Fernando Almeida Moreira, Klaus Reichardt

“…Utilizing artificially compacted 30 mm high soil blocks, in a series of experiments, these lines were compared to the cultivar Fava Larga taken as a standard. …”
Get full text

A select inhibitor of MORC2 encapsulated by chimeric membranecoated DNA nanocage target alleviation TNBC progression by Xiaohan Su, Yunbo Luo, Yali Wang, Peng Qu, Jun Liu, Shiqi Han, Cui Ma, Shishan Deng, Qi Liang, Xiaowei Qi, Panke Cheng, Lingmi Hou

“…Subsequently, Angoline was identified as an inhibitor of MORC2 protein by high-throughput screening and can significantly kill the TNBC cells by blocking cell cycle and inducing apoptosis. Furthermore, the biomimetic nanodrug delivery system (PMD) was designed by encapsulating tetrahedral DNA nanostructures with biomimetic cell membrane, and it can efficiently evade the phagocytosis of immune system and target TNBC tissue. …”
Get full text

Mechanical forces pattern endocardial Notch activation via mTORC2-PKC pathway by Yunfei Mu, Shijia Hu, Xiangyang Liu, Xin Tang, Jiayi Lin, Hongjun Shi

“…However, the precise mechanism underlying Notch activation remains elusive. By transiently blocking the heartbeat of E9.5 mouse embryos, we found that Notch activation in the arterial endothelium was dependent on its ligand Dll4, whereas the reduced expression of Dll4 in the endocardium led to a ligand-depleted field, enabling Notch to be specifically activated in AVC and OFT by regional increased shear stress. …”
Get full text

The Utility of Endoscopic Ultrasound Guided Fine Needle Aspiration in the Diagnosis of Infectious Diseases—Report of Three Cases by Mauro Ajaj Saieg, Felipe Yazawa, Manuela Horta, Lucio G. Rossini, Mabel Tatty Medeiros Fracassi, Fabíola Del Carlo Bernardi

“…In conclusion, EUS was successful not only in obtaining enough cells for morphological analysis, but also for the production of cell blocks and assessment of the presence of the microorganisms by special stains. …”
Get full text

Study on Influencing Factors of Asphalt-Aggregate Stripping Mechanism by Fuyu Wang, Yan Li, Liting Yu, Weichen Pang

“…The test results show that the diffusion rate of water in modified asphalt film is one half of that of base asphalt, so the blocking water ability of modified asphalt is better than that of matrix asphalt. …”
Get full text

Admission Control for Multiservices Traffic in Hierarchical Mobile IPv6 Networks by Using Fuzzy Inference System by Jung-Shyr Wu, Shun-Fang Yang, Chen-Chieh Huang

“…It is evident that these CAC schemes can reduce the probability of the handoff dropping and the cell overload and limit the probability of the new call blocking.…”
Get full text

The Role of Matrix Metalloproteinase-9 in Atherosclerotic Plaque Instability by Tiewei Li, Xiaojuan Li, Yichuan Feng, Geng Dong, Yuewu Wang, Junmei Yang

“…MMP-9 deficiency or blocking MMP-9 expression can inhibit plaque inflammation and prevent atherosclerotic plaque instability. …”
Get full text

Does Repeated Ticking Maintain Tic Behavior? An Experimental Study of Eye Blinking in Healthy Individuals by Daniel J. V. Beetsma, Marcel A. van den Hout, Iris M. Engelhard, Marleen M. Rijkeboer, Danielle C. Cath

“…The experimental group with air puffs+ blinking experienced a decrease in subjective annoyance of the air puff, but habituation of the EMG response was blocked and length of EMG response increased. In the control groups (air puffs without instruction to blink, no air puffs), these effects were absent. …”
Get full text

Key Role of Human ABC Transporter ABCG2 in Photodynamic Therapy and Photodynamic Diagnosis by Toshihisa Ishikawa, Hiroshi Nakagawa, Yuichiro Hagiya, Naosuke Nonoguchi, Shin-ichi Miyatake, Toshihiko Kuroiwa

“…Protein kinase inhibitors, including imatinib mesylate and gefitinib, are suggested to potentially enhance the efficacy of photodynamic therapy by blocking ABCG2-mediated porphyrin efflux from cancer cells. …”
Get full text

Mathematical modeling of liver fibrosis by Avner Friedman, Wenrui Hao

“…We use the model to explore the efficacy of potential and currently used drugs aimed at blocking the progression of liver fibrosis. We also use the model to develop a diagnostic tool based on a combination of two biomarkers.…”
Get full text

Hyperkalemia Induced Brugada Phenocopy: A Rare ECG Manifestation by Muhammad Ameen, Ghulam Akbar, Naeem Abbas, Ghazi Mirrani

“…Various electrolyte disturbances and ion channels blocking drugs could also provoke BrS ECG findings without genetic BrS. …”
Get full text

Correction of a Class III Malocclusion with a Functional Shift and Severe Crowding by Yahya A. Alogaibi, Ahmad A. Al-Fraidi, Manar K. Alhajrasi, Ali A. Hassan

“…The patient also showed severe upper arch crowding with blocked-out canines and mild crowding in the lower arch. …”
Get full text

Deadbeat Control of a Modified Single-Phase Five-Level Photovoltaic Inverter with Reduced Number of Switches by Mohsen Ghorbanali Afjeh, Mojtaba Babaei, Mohsen Alizadeh Bidgoli, Amir Ahmarinejad

“…Compared with the presented inverters, the introduced topology has the advantage of decreased device count and the first switching frequency for high blocking voltage switches. The proposed PV inverter is implemented without clamping diodes and transformers, which leads to a decrement in size and, consequently, the weight of the converter. …”
Get full text

OLIG2 mediates a rare targetable stem cell fate transition in sonic hedgehog medulloblastoma by Kinjal Desai, Siyi Wanggou, Erika Luis, Heather Whetstone, Chunying Yu, Robert J. Vanner, Hayden J. Selvadurai, Lilian Lee, Jinchu Vijay, Julia E. Jaramillo, Jerry Fan, Paul Guilhamon, Michelle Kushida, Xuejun Li, Gregory Stein, Santosh Kesari, Benjamin D. Simons, Xi Huang, Peter B. Dirks

“…Inactivation of Olig2 blocks stem cell activation and tumour output. Targeting this rare OLIG2-driven proliferative programme with a small molecule inhibitor, CT-179, dramatically attenuates early tumour formation and tumour regrowth post-therapy, and significantly increases median survival in vivo. …”
Get full text

Interlayer Simplified Depth Coding for Quality Scalability on 3D High Efficiency Video Coding by Mengmeng Zhang, Hongyun Lu, Huihui Bai

“…To further improve the coding performance, the coded prediction quadtree and texture data from corresponding SDC-coded blocks in the base layer can be used in interlayer simplified depth coding. …”
Get full text