The PROPHECI trial: a phase II, double-blind, placebo-controlled, randomized clinical trial for the treatment of pseudoxanthoma elasticum with oral pyrophosphate by Laetitia Clotaire, Isabelle Rubera, Christophe Duranton, Jocelyn Gal, Emmanuel Chamorey, Hélène Humeau, Samir Yamani, Christine Chiaverini, Serge Willoteaux, Bernard Padovani, Laurie Mourozeau, Adam Mainguy, Stéphanie Baillif, Ludovic Martin, Georges Leftheriotis

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Resistance of <i>Wolbachia</i> to Trimethoprim: Insights into Genes Encoding Dihydrofolate Reductase, Thymidylate Synthase and Serine Hydroxymethyltransferase in the Rickettsiales by Ann M. Fallon

“…Bacterial and eukaryotic dihydrofolate reductase (DHFR) enzymes are essential for DNA synthesis and are differentially sensitive to the competitive inhibitors trimethoprim and methotrexate. …”
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Atrial Cardiomyopathy: From Diagnosis to Treatment by Zheyu Liu, Tao Liu, Gang Wu

“…Furthermore, persistent AF can exacerbate structural and electrical remodeling, as well as mechanical dysfunction of the atria, creating a vicious cycle. To date, the relationship between ACM, AF, and cardiogenic embolism remains unclear. …”
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Critical Management of Haemodynamically Unstable Acute Pulmonary Embolism in COVID-19 by Eka Adip Pradipta, Vienna Rossimarina, Indira Kemalasari, Siska Suridanda Danny

“…In the isolation ward, he had a cardiac arrest, and bedside echocardiography showed a fresh thrombus had developed in the right atria with signs of acute right ventricular dysfunction. …”
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Monumentos, marcas y homenajes: la última dictadura, los usos del pasado y la construcción de narrativas autolegitimantes (Buenos Aires, 1979-1980) by Laura Schenquer, Lucía Cañada

“…Hemos clasificado estas intervenciones oficiales (que contaron con la colaboración de sectores privados) de acuerdo con dos objetivos centrales: a) la reivindicación de una tradición militar con el propósito de componer la imagen de un ejército venerable; y b) el reconocimiento sacrificial de los militares “caídos” en combate contra el enemigo de la patria.…”
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Interculturalidad, plurinacionalidad y decolonialidad: las insurgencias político-epistémicas de refundar el Estado by CATHERINE WALSH

“…Requiere pasar de las resistencias a nuevas insurgencias -de transgredir, interrumpir, incidir e in-surgir-; al poner como meollo del asunto, los patrones del poder colonial que aún perviven para -y desde allí- plantear, cultivar y ejercitar articulaciones y construcciones distintas que alienten un cambio radical y descolonizador que pretende no solo acabar con el Estado colonial y el modelo neoliberal -como dice Evo Morales-, sino también hacer entre todos una patria distinta.…”
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Identidade étnica, índios e direito penal no Brasil:paradoxos insustentáveis by Daize Fernanda Wagner

“…Todavia, não é esse o encaminhamento dado pela magistratura pátria quando depara com indígenas réus em processos penais. …”
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Cross-agency working when conducting a pragmatic RCT for older victims of crime: our experiences and lessons learned by Marc Serfaty, Jessica Satchell, Gloria K. Laycock, Chris R. Brewin, Marta Buszewicz, Gerard Leavey, Vari M. Drennan, Jonathan Cooke, Anthony Kessel

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Effect of a Nutritional Education Intervention on the Reduction of Added Sugar Consumption in Schoolchildren in Southeastern Mexico: Community Study by Carmen Morales-Ruán, Teresa Shamah-Levy, Danae Gabriela Valenzuela-Bravo, Rebeca Uribe-Carvajal, Corin Hernández-Palafox, María Concepción Medina-Zacarías, Ignacio Méndez Gómez-Humarán

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The Influence of Vitamin D Receptor Gene Polymorphisms in Spondyloarthritis by Janisleya Silva Ferreira Neves, Jeane Eliete Laguila Visentainer, Denise Manjurma da Silva Reis, Marco Antonio Rocha Loures, Hugo Vicentin Alves, Fernanda Formaggi Lara-Armi, Josiane Bazzo de Alencar, Joana Maira Valentin Zacarias, Ana Maria Sell

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Developing generic clinical trial animated explainer videos in the UK: results of a survey and case study by Clare Calvert, Vicki S. Barber, Duncan Appelbe, Kirsty Sprange, Claire Nollett, Fiona Lugg-Widger, Samantha Tanner, Duncan B. Richards

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COVID-19 EM PEDIATRIA: PERFIL EPIDEMIOLÓGICO DOS CASOS SUSPEITOS by Khétene Joyce Freitas Zacarias, Victoria Liery Ribeiro Alves, Yure Batista de Sousa, Mirela Lopes Figueiredo, Ana Augusta Maciel de Souza, Patrícia Fernandes do Prado

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NF-κB-Specific Suppression in Cardiomyocytes Unveils Aging-Associated Responses in Cardiac Tissue by Letícia Aparecida Lopes Morgado, Larissa Maria Zacarias Rodrigues, Daiane Cristina Floriano Silva, Bruno Durante da Silva, Maria Claudia Costa Irigoyen, Ana Paula Cremasco Takano

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Hypermethylation of Hif3a and Ifltd1 is associated with atrial remodeling in pressure-overload murine model by Keiko Abe, Tetsuo Sasano, Yurie Soejima, Haruhisa Fukayama, Shigeru Maeda, Tetsushi Furukawa

“…After 14 days, the TAC-operated mice showed a significant increase in the atrium/body weight ratio and deposition of collagen fibers in the atria. A comprehensive analysis using RNA-sequencing (RNA-Seq) and methyl-CpG-binding domain sequencing (MBD-Seq) in the left atrial tissue identified Hif3a and Ifltd1 as showing increased DNA methylation in their promoter regions and decreased RNA expression. …”
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Reexpansion Pulmonary Edema following Tube Thoracostomy in a Pediatric Patient with Anterior Mediastinal Mass by Sung-Wook Choi, Deborah A. Romeo, David A. Gutman, Jennifer V. Smith

“…A chest computerized tomography (CT) demonstrated a large pleural effusion causing tracheal shift and left bronchus compression as well as an anterior mediastinal mass causing compression of the right atria and right ventricle. Tube thoracostomy was performed in the operating room (OR) with deep sedation. …”
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The effects of diacylglycerol edible oil intervention in patients with chronic metabolic syndrome combined with asymptomatic hyperuricemia: study protocol for a multicenter, prospe... by Gui-yu Li, Cui-feng Zhu, Zhao-qi Huang, Chun-li Piao, Jia-jun Yu, Li Wang, Qiang Zeng, Yu-yu Lei, Yue Li, Xiao-ling Zhu, Zhen-tian Zhang, Tian-hua Huang, Meng-shuang Li, Shu-zhong Lin, Nai-wen Zhang, Fangyingnan Zhang, Yong-hua Wang, Dan-ping Xu

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Gut microbiota and atrial cardiomyopathy by Tingting Sun, Beibei Song, Bo Li

“…Atrial cardiomyopathy is a multifaceted heart disease characterized by structural and functional abnormalities of the atria and is closely associated with atrial fibrillation and its complications. …”
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Análise de mudanças na cobertura vegetal do Pará utilizando o Google Earth Engine by Laízy de Santana Azevedo, Evely Ferreira do Nascimento, Leonardo Carlos Barbosa, Willian dos Santos Ferreira, José Rubens Scatimburgo Silva, Karoline Borges

“…No Brasil, a Floresta envolve nove Estados que fazem parte da Bacia amazônica cada um deles possuindo porções da Floresta Amazônica. …”
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Echocardiographic Features of Cardiomyopathy in Emery-Dreifuss Muscular Dystrophy by Michał Marchel, Agnieszka Madej-Pilarczyk, Agata Tymińska, Roman Steckiewicz, Janusz Kochanowski, Julia Wysińska, Ewa Ostrowska, Paweł Balsam, Marcin Grabowski, Grzegorz Opolski

“…A significant number of EDMD patients present LV dilatation and different degrees of systolic dysfunction. Dilatation of the atria dominates over ventricle dilatation. We did not present any significant differences between EDMD1 and EDMD2 in terms of the morphology and the function of the heart.…”
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Robotic-assisted surgery and kinematic alignment in total knee arthroplasty (RASKAL study): a protocol of a national registry-nested, multicentre, 2×2 factorial randomised trial as... by Ian A Harris, Samuel J MacDessi, Aziz Bhimani, Darren B Chen, Ian Harris, Michelle Lorimer, David Parker, Tamara Hooper, Richard Boyle, Jonathan Mulford, Daniel Franks, Gregory C Wernecke, Durga Bastiras, Emma Heath, Anthony Leong, Brett Fristch, David Penn, George Kirsh, John Limbers, Julian Yu, Maurice Guzman, Peter McEwen

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