Hospitalizations, emergency medical care utilization, and contacts with the regional on-call medical services among nursing home residents in Germany: a cross-sectional study in 44... by Paula Lienesch, Heinz Rothgang, Ansgar Gerhardus, Karin Wolf-Ostermann, Falk Hoffmann, Jonas Czwikla

“…Methods Cross-sectional data from the “Needs-based provision of medical care to nursing home residents” (MVP-STAT) study were analyzed, which were collected in 44 German nursing homes from 442 residents in 2018/2019. Proportions of residents with at least one hospitalization, emergency medical care utilization (via the nationwide phone number 112), and contact with an on-call medical service (nationwide via 116117) over the previous 12 months were determined. …”
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Enhancing surveillance for dengue fever in Oyo State, Nigeria – a one health approach by Olawale Sunday Animasaun, Joseph Ojonugwa Shaibu, Busayo Kayode Akomolafe, Olamide Priscilla Animasaun, Piring’ar Mercy Niyang, Olukemi Titilope Olugbade, Akinfemi Oyewumi Akinyode, Ibukun Akinsola Omisakin, Adedapo Olufemi Adeogun, Rosemary Ajuma Audu

“…Result The overall seroprevalence of DENV was 128/289 (44.2%) with 19/289 (6.6%) and 109/289 (37.7%) being IgM and IgG positive respectively. …”
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Efficacy and Safety of Aprocitentan in the Treatment of Hypertension: A Meta-Analysis of Evidence from Randomized Controlled Trials by Li Zheng, Ming Liu, Xiaotong Gu, Yatong Zhang, Yan Wang

“…Results: This meta-analysis included five RCTs, which incorporated 1224 patients, and displayed that aprocitentan can reduce the mean sitting systolic blood pressure (msSBP) [(low dose subgroup: mean difference (MD): –3.85 mmHg; 95% confidence interval (CI): –7.47 to –0.23; p = 0.040; medium dose group: MD: –5.56 mmHg; 95% CI: –10.69 to –0.44; p = 0.030)], mean sitting diastolic blood pressure (msDBP) (low dose subgroup: MD: –3.95 mmHg; 95% CI: –4.06 to –3.85; p < 0.001; medium dose group: MD: –4.75 mmHg; 95% CI: –5.91 to –3.60; p < 0.001), 24-hour ambulatory systolic blood pressure (maSBP) (low dose group: MD: –4.18 mmHg; 95% CI: –4.32 to –4.04; p < 0.001; medium dose group: MD: –5.89 mmHg; 95% CI: –6.03 to –5.75; p < 0.001), and 24-hour ambulatory diastolic blood pressure (maDBP) (low dose group: MD: –4.33 mmHg; 95% CI: –4.42 to –4.24; p < 0.001; medium dose group: MD: –5.82 mmHg; 95% CI: –5.91 to –5.73; p < 0.001). …”
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Assessment of Tumor Burden Score as a Feasible and Reliable Tool for Prognosis Prediction for Hepatocellular Carcinoma Undergoing Hepatectomy: A Multicenter, Retrospective Study by Guan R, Zheng Z, Deng M, Mei J, Lin Y

“…Finally, univariate and multivariate cox analysis was used to determine independent prognostic predictors.Results: About 44.2% (n=1343) of patients had low TBS, 38.8% (n=1182) had intermediate TBS and 17% (n=519) had high TBS. …”
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Response to Aflibercept Therapy in Three Types of Choroidal Neovascular Membrane in Neovascular Age-Related Macular Degeneration: Real-Life Evidence in the Czech Republic by Jan Nemcansky, Alexandr Stepanov, Michal Koubek, Miroslav Veith, Yun Min Klimesova, Jan Studnicka

“…Mean baseline CRT ± SD for Type 1 lesions was 442.4 ± 194.9 μm, and then 302.5 ± 144.4 μm, 299.7 ± 128.5 μm, and 277.7 ± 106.5 μm at 16, 32, and 48 weeks, respectively. …”
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Engagement and Follower Growth: Social Media Strategies of Swiss Athletes at the Paris Olympics by Larssyn Staley, Florian Droux

“…However, post frequency negatively correlated with the percentage of follower growth (r = −.442, p < .05). Notably, post type and athletic performance were negatively correlated (r = −.214, p < .05). …”
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基于红外相机技术的南滚河国家级自然保护区鸟兽多样性初步监测 by 陈彦一, 肖剑平, 王志胜, 陈德明, 李 旭

“…</i>调查到的兽类中相对丰富度最高的为赤麂<i>(Muntiacus vaginalis</i>,<i>I</i>_RA=10.19),其次是野猪(<i>Sus scrofa</i>,<i>I</i>_RA=9.25)、水鹿(<i>I</i>_RA=4.42)、黄鼬(<i>Mustela sibirica</i>,<i>I</i>_RA=2.36); 鸟类中相对丰富度最高的为白尾蓝地鸲(<i>Myiomela leucurum</i>,<i>I</i>_RA=2.34),其次是白鹇(<i>I</i>_RA=1.99)、紫啸鸫(<i>Myophonus caeruleus</i>,<i>I</i>_RA=1.24)、红原鸡(<i>I</i>_RA=0.75)。…”
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Etiology of Hospital-Acquired Pneumonia (HAP) and Ventilator-Associated Pneumonia (VAP) in Tertiary-Care Hospitals in Thailand: A Multicenter, Retrospective Cohort Study by Rongrungruang Y, Plongla R, Pleumkanitkul S, Hantrakun V, Khawcharoenporn T

“…The top three causative pathogens of NP were Acinetobacter baumannii (44.2%), Pseudomonas aeruginosa (34.6%), and Klebsiella pneumoniae (28.3%). …”
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Retrospective analysis of amantadine response and predictive factors in intensive care unit patients with non-traumatic disorders of consciousness by Corinna Blum, Constanze Single, Kornelia Laichinger, Anna Hofmann, Tim W. Rattay, Tim W. Rattay, Kamaldeen Adeyemi, Reimer Riessen, Michael Haap, Helene Häberle, Ulf Ziemann, Annerose Mengel, Katharina Feil

“…Machine learning techniques were used to predict response to treatment.ResultsOf 442 patients (mean age 73.2 ± 10.7 years, 41.0% female), 267 (60.4%) were responders. …”
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The aptamer BC 007 for treatment of dilated cardiomyopathy: evaluation in Doberman  Pinschers of efficacy and outcomes by Sabine Werner, Gerd Wallukat, Niels‐Peter Becker, Katrin Wenzel, Johannes Müller, Ingolf Schimke, Gerhard Wess

“…Compared with the controls, DP treated with BC 007 showed a significantly longer survival time [572 days, interquartile range (IQR) 442–840 days] vs. Control group 1 (266 days, IQR 97–438 days; logrank: P = 0.009) and Control group 2 (229 days, IQR 174–319 days; logrank: P = 0.012). …”
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Associations of health literacy with metabolic status and quality of life among comunity patients with type 2 diabetes in Shanghai by YANG Liping, SONG Haihong, SHEN Jue, GAO Jinli, ZHANG Zhiping, QIAN Liuyu, GONG Huan

“…The average QoL score was (44.1±9.2) points of which (44.0±9.5) points for males and (44.2±8.9) points for females. The achievement rates of HbA1c, total cholesterol (TC), and triglycerides (TG) were 51.6%, 30.3%, and 64.8%, respectively. …”
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综合性干预手段对偏侧咀嚼的肌功能评价 by 杨丹, 王云, 汪萌芽

“…【结果】①干预组，干预前后LDA（M1）、RMM（M2）平均肌电差值分别为-7.4（-12.98，-1.84）、-2.28（-4.42，-0.13），差异有统计学意义（＜0.05）；干预后M2中RMM、RDA平均肌电值分别为9.62（5.99，9.98）、9.96（7.91，12.62），与对照组M2中RMM［4.88（3.87~5.88）］、RDA［5.05（3.07~8.12）］平均肌电值相比，差异有显著统计学意义（＜0.01）。…”
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Effects of landslide hazards on quality of stream water and sediments by O. Phewnil, T. Pattamapitoon, N. Semvimol, W. Wararam, K. Duangmal, A. Intaraksa, K. Chunkao, P. Maskulrath, S. Hanthayung, P. Wichittrakarn

“…For Uttaradit, the average arsenic concentrations were 0.22 ± 0.09 milligram per kilogram, 0.01 ± 0.14 milligram per liter, and 9.74 ± 4.42 milligram per kilogram in upland soil, water, and sediment samples, respectively. …”
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Factors Associated with Management of Workplace Violence Competence Among Chinese Nursing Interns by Meng L, He L, Ouyang L, Fu M, Li P, He Y

“…Data were collected via online survey questionnaires using the Management of Workplace Violence Competence Scale (MWVCS), the Patient Risk Identification Ability Assessment Questionnaire, and the Professional Identity Questionnaire for Nursing Students (PIQNS).Results: Among participants, 91.1% were female (n=744), 68.1% (n=556) were between 21 to 23 years old, and 54.1% (n=442) obtained a bachelor’s degree. The score of management of workplace violence competence was 123.25 (SD=11.06). …”
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Oxidative Stress, Antioxidant Capacity, and Inflammatory Markers in Patients with Idiopathic Complete Heart Block by Shobhit Shah, Monika Bhandari, Pravesh Vishwakarma, Wahid Ali, Mohammad Kaleem Ahmad, Abhishek Singh, Ayush Shukla, Akhil Kumar Sharma, Gaurav Chaudhary, Akshyaya Pradhan, Sharad Chandra, Rishi Sethi, S. K. Dwivedi

“…Serum IL-5 (pg/ml) has a mean value of 67.347 ± 20.445 (P < 0.001) in controls and 481.442 ± 28.8995 in patients. The patients’ mean serum TNF-alpha value (pg/ml) is 196.741 ± 73.771, whereas the controls’ mean value is 144.530 ± 42.599 (P = 0.081). …”
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Indicadores de qualidade de vida de homens idosos de Florianópolis: um estudo descritivo by Eneida Maria Troller Conte, Adair da Silva Lopes

“…Encontrar com os amigos era o principal motivo para freqüentar a Praça XV de Novembro de Florianópolis citado por 44,2% dos entrevistados. Nos componentes da qualidade de vida, 86,5% apresentaram respostas positivas para as questões relativas à satisfação com a vida e à felicidade, 76,9% responderam expressar seus sentimentos e 82,7% aceitam as pessoas como elas são. …”
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Global, regional, and national trends in drug use disorder mortality rates across 73 countries from 1990 to 2021, with projections up to 2040: a global time-series analysis and mod... by Soeun Kim, Hayeon Lee, Selin Woo, Hyeri Lee, Jaeyu Park, Tae Kim, Guillaume Fond, Laurent Boyer, Masoud Rahmati, Lee Smith, Guillermo F. López Sánchez, Elena Dragioti, Christa J. Nehs, Jinseok Lee, Hyeon Jin Kim, Jiseung Kang, Dong Keon Yon

“…Notably, HICs showed a significant increase in DUD mortality from 1.43 deaths per 1,000,000 people (95% CI, −1.55 to 4.42) in 1990 to 17.19 deaths per 1,000,000 people (95% CI, 13.84–20.53) in 2021. …”
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局部应用上皮钠通道阻滞剂对干眼兔泪液分泌的影响 by 魏园, 陈晓敏, 陈冬翠, 周世有

“…【结果】皮下给药12d后，对照组泪液分泌实验结果为（17.00±0.37）mm/5min，实验组泪液分泌实验结果为（4.42±1.34）mm/5min（P<0.001，n=8），治疗组泪液分泌实验结果（14.25±0.54）mm/5min（P>0.05，n=8）。…”
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MSCs Contribute to the Conversion of Ly6Chigh Monocytes into Ly6Clow Subsets under AMI by Wenbin Lu, Genshan Ma, Zulong Sheng, Qingjie Wang, Lijuan Chen, Junhua Qi, Ronghui Shi, Jingjing Ji, Zhenjun Ji, Qiming Dai

“…We also found significantly decreased TUNEL+ cardiac myocytes (15.45%±4.42% vs. 22.78%±6.40%, p<0.001) in mice with high expression levels of NR4A1 compared to mice with low expression levels. …”
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Maroteaux-Lamy综合征的ARSB基因分析及新突变的致病性鉴定 by 郭东炜, 潘伟绵, 杜敏联, 郭奕斌

“…【结果】 1） 7个家系先证者的基因检测结果分别为：No1： c.574T>C，p.C192R纯合错义突变；No2： c.160G>A/p.D54N（来 自其母）和c.1197C>G/p.F399L（来自其父）的复合杂合子；No3：仅检出c.1072G>A/p.V358M和IVS5as（-27）A> C变异，但酶检和临床表型符合VI型；No4：为c.281C>T，p.S94L（新突变，来自其母）和IVS5as（-27）A>C（来自 其父）的复合杂合子；No5：为c.1197C>G，p.F399L纯合错义突变；No6：为c.1197C>G，p.F399L（来自其母）和 c.1379C>T，p.S460F（新突变，来自其父）的复合杂合子；No7：为c.499G>A，p.G167R（来自其父）和c.1325C> T，p.T442M（来自其母）的复合杂合子。2）新突变鉴定结果：对正常ARSB酶蛋白和p.S94L突变酶蛋白的空间构 象的预测比对结果显示，两者有明显区别；跨物种保守性分析结果显示， p.94突变点所在氨基酸（S）在物种进化 过程中具有高度保守性；PROVEAN、SIFT和PolyPhen-2软件对p.S94L预测结果分别为：Deleterious、Damaging和 Probablydamaging。…”
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