Cost-utility analysis of combination medical therapies in chronic coronary syndrome: a comparative study using real-world and patient-level data from Iran by Fatemeh Soleymani, Parham Sadeghipour, Majid Davari, Abbas Kebriaeezadeh, Behzad Fatemi, Mohammad Reza Maracy, Nasim Naderi, Saman Zartab

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Impact of loneliness on suicidal ideation during the COVID-19 pandemic: findings from a cross-sectional online survey in Japan by Takahiro Tabuchi, Ryo Okubo, Hirokazu Tachikawa, Midori Matsushima, Haruhiko Midorikawa, Miyuki Aiba

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Intratumoral and peritumoral radiomics of MRI predicts pathologic complete response to neoadjuvant chemoimmunotherapy in patients with head and neck squamous cell carcinoma by Jie Sun, Bin Zhang, Shuixing Zhang, Xuewei Wu, Ruhang Ma

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Does awake prone positioning prevent the use of mechanical respiratory support or death in COVID-19 patients on standard oxygen therapy hospitalised in general wards? A multicentre... by Benjamin Planquette, Christophe Perrin, Thierry Boulain, Mai-Anh Nay, Louis Bernard, Laurent Plantier, Léa Colombain, Jérémy Clément, Aymeric Sève, Sylvie Druelle, Marine Morrier, Jean-Baptiste Lainé, Grégory Corvaisier, Nicolas Bizien, Xavier Pouget-Abadie, Adrien Bigot, Elsa Nyamankolly, Guillaume Fossat

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Vulnerability for alcohol use disorder after adverse childhood experiences (AUDACE): protocol for a longitudinal fMRI study assessing neuropsychobiological risk factors for relapse by Falk Kiefer, Cagdas Türkmen, Noah Machunze, Haoye Tan, Sarah Gerhardt, Sabine Vollstädt-Klein

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Prevalence and factors associated with depression and anxiety among patients recovered from COVID-19: a cross-sectional study in a tertiary care hospital in Nepal by Biraj Man Karmacharya, Kamal Gautam, Kalpana Chaudhary, Prasanna Rai, Shalik Ram Dhital, Shrinkhala Shrestha, Bandana Paneru, Akina Shrestha

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Effects and utility of an online forward triage tool during the SARS-CoV-2 pandemic: a mixed method study and patient perspectives, Switzerland by Thomas C Sauter, Wolf E Hautz, Martin Müller, Meret E Ricklin, Janet Michel, Annette Mettler, Raphael Stuber, Philipp Jent

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On the time spent preparing grant proposals: an observational study of Australian researchers by Nicholas Graves, Adrian G Barnett, Philip Clarke, Danielle L Herbert

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Does improving sleep lead to better mental health? A protocol for a meta-analytic review of randomised controlled trials by Georgina Rowse, Alexander J Scott, Thomas L Webb

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Incomplete recovery in patients with minor head injury directly discharged home from the emergency department: a prospective cohort follow-up study by Bram Jacobs, Joukje van der Naalt, Jan Cornelis ter Maaten, Sophie Maria Coffeng, Laura Jane Kim

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Healthy Life Centres: a 3-month behaviour change programme’s impact on participants’ physical activity levels, aerobic fitness and obesity: an observational study by Ellen Eimhjellen Blom, Eivind Aadland, Ane Kristiansen Solbraa, Line Merethe Oldervoll

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EXtending Omalizumab Treatment Intervals in patients with Chronic spontaneous urticaria (EXOTIC): protocol of a multicentre, randomised, open-label, non-inferiority trial by Alexander Egeberg, Ditte Georgina Zhang, Christian Vestergaard, Simon Francis Thomsen, Jennifer Astrup Sørensen, Misbah Noshela Ghazanfar, Zarqa Ali, Jacob Thyssen

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Barriers and facilitators regarding the implementation of policies and programmes aimed at reducing adolescent pregnancy in Ghana: an exploratory qualitative study by Melissa Kang, Bright Opoku Ahinkorah, Lin Perry, Fiona Brooks

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Modulating lipid metabolism improves tumor immunotherapy by Yi Zhang, Yu Ping, Qiuqing Fan

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Mapping evidence on the regulations affecting accessibility, availability and management of snake antivenom globally: a scoping review protocol by Kabelo Kgarosi, Ramsha Majeed, Janette Bester, Morné Strydom

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Deciding on life-saving treatment after a violent suicide attempt: an ethical case report by Robert Wichers, Hanna M Heller, Sisco van Veen

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COVID-19 in the context of pregnancy, infancy and parenting (CoCoPIP) study: protocol for a longitudinal study of parental mental health, social interactions, physical growth and c... by Topun Austin, Jane Barlow, Ezra Aydin, Staci M Weiss, Kevin A Glasgow, Mark H Johnson, Sarah Lloyd-Fox

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Hand acceleration time (HAT) as a diagnostic tool in the assessment of haemodialysis access-induced distal ischaemia (HAIDI): study protocol for a prospective cohort study in the B... by Sebastian Videla, Begoña Gonzalo, Emma Espinar, Siloé Palacios, Carolina Herranz, Elena Iborra Ortega

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Cognitive prehabilitation for geriatric patients undergoing elective surgery: a PRISMA-P-compliant protocol for a systematic review by Yu He, Nianyi Sun, Wenchen Zou, Anren Zhang, Xiaochai Han, Caitao Chen

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Medication following bariatric surgery for type 2 diabetes mellitus (BY-PLUS) study: rationale and design of a randomised controlled study by Alexander Dimitri Miras, Carel le Roux, Alexis Sudlow, Ricardo Vitor Cohen, Hassan Kahal, Dimitri J Pournaras, Jill Townley, Helen Heneghan

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