Interventional radiology versus operative management for splenic injuries: a study protocol for a systematic review and meta-analysis by Kazuma Yamakawa, Masahiro Kashiura, Noritaka Yada

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Lack of effect of Lactobacillus rhamnosus GG and Bifidobacterium lactis Bb12 on beta-cell function in children with newly diagnosed type 1 diabetes: a randomised controlled trial by Hania Szajewska, Agnieszka Szypowska, Lidia Groele, Mieczysław Szalecki, Jolanta Świderska, Marta Wysocka-Mincewicz, Agnieszka Ochocińska, Anna Stelmaszczyk-Emmel, Urszula Demkow

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Age at diagnosis as a prognostic factor in selected categories of juvenile idiopathic arthritis by Kristiina Aalto, Hannu Kautiainen, Anders Fasth, Marek Zak, Troels Herlin, Marite Rygg, Ellen Berit Nordal, LILLEMOR BERNTSON, Mia Glerup, Veronika Rypdal, Ellen Arnstad, Suvi Peltoniemi, Katariina Rebane, Anna-Kaisa Tuomi

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Study protocol: treatment with caffeine of the very preterm infant in the delivery room: a feasibility study by Giancarlo la Marca, Fabio Mosca, Alessandra Cecchi, Giulia Remaschi, Domenica Mercadante, Luca Boni

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Tuberculosis: treatment failure, or failure to treat? Lessons from India and South Africa by Nesri Padayatchi, Amrita Daftary, Naressa Naidu, Madhukar Pai

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Representation of racialised and ethnically diverse populations in multicentre randomised controlled trials of GLP-1 medicines for obesity: a systematic review and meta-analysis of... by Ravi Retnakaran, Caroline K Kramer, Lisa Richardson, Yaanu Jeyakumar, Shohinee Sarma

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Dickkopf 1 impairs the tumor response to PD-1 blockade by inactivating CD8+ T cells in deficient mismatch repair colorectal cancer by Yuan Li, Jian Zheng, Zhizhong Pan, Penghui Zhou, Guochen Liu, Wu Jiang, Pei-Rong Ding, Zexian Liu, Qiaoqi Sui, Dingxin Liu, Jinghua Tang, Lingheng Kong, Kai Han, Leen Liao, Qingjian Ou, Binyi Xiao, Yihong Ling, Jiewei Chen, Zhixiang Zuo

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Improbable data characteristics and extreme effects of apple cider vinegar on weight loss by James Heathers, Vahid Malbouby, Eric T Trexler

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How do socioeconomic inequalities and preterm birth interact to modify health and education outcomes? A narrative systematic review by Ben Barr, David Taylor-Robinson, Andy Pennington, Daniela K Schlüter, Philip McHale, Katie Fahy

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Machine learning predicted fast progression after initiation of immune checkpoint inhibitors in advanced non-small cell lung cancer by Martin Stockler, Yu Yang Soon, Chee Khoon Lee, Teng Hwee Tan

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Successful awake proning is associated with improved clinical outcomes in patients with COVID-19: single-centre high-dependency unit experience by Najib M Rahman, Gareth Hynes, Ling-Pei Ho, Rob J Hallifax, William G Flight, John M Wrightson, Stephen J Chapman, Nayia Petousi, Mona Bafadhel, Annabel H Nickol, Emily Fraser, Rachel K Hoyles, Ian D Pavord, Anny Sykes, Maxine Hardinge, Chris D Turnbull, Benedict ML Porter, Patrick JD Elder, Sarah B Evans, Rachel Lardner, Kirsty Archer, Henry V Bettinson, Peter Saunders, Alastair Moore, Nicholas P Talbot

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Novel, genetically induced mouse model that recapitulates the histological morphology and immunosuppressive tumor microenvironment of metastatic peritoneal carcinomatosis by Chien-Fu Hung, Ssu-Hsueh Tseng, Sung-Taek Park, Brandon Lam, Ya-Chea Tsai, Max A Cheng, Emily Farmer, Deyin Xing

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Associations between 24-hour activity behaviours and emotional and behavioural problems of left-behind children: a component analysis of data from a cross-sectional study by Rui Li, Bin Lu, Zan Huang, Jiaying Lou, Yulan Zhou

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Loneliness, social isolation and incident chronic kidney disease among patients with diabetes by Xiang Li, Yoriko Heianza, Lu Qi, Hao Ma, Jian Zhou, Xuan Wang, Rui Tang

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Intratumoral microbiota predicts the response to neoadjuvant chemoimmunotherapy in triple-negative breast cancer by Kun Wang, Yuhong Huang, Hao Peng, Lu Yang, Yilin Chen, Teng Zhu, Liulu Zhang, Minyi Cheng, Cangui Wu, Peiyong Li, Minting Liang, Xiaoqi Zhang

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Awareness of obstetric fistula and its associated factors among reproductive-age women in Ethiopia: a multilevel analysis of Ethiopian Demographic and Health Survey data: a cross-s... by Kegnie Shitu, Wallelign Aleminew, Bezawit Mulat

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Cost-effectiveness of an 8-week supervised education and exercise therapy programme for knee and hip osteoarthritis: a pre–post analysis of 16 255 patients participating in Good Li... by Ewa M Roos, Søren T Skou, Rikke Ibsen, Jakob Kjellberg, Dorte T Grønne

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Comparative efficacy and safety of statins for osteoporosis: a study protocol for a systematic review and network meta-analysis by Wei Zhu, Nan Xiang, Guangwen Zhou, Mengxin Xiong, Yaojun Xue, Ali Deng, Zhangkui Tan

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Antiplatelet therapy is associated with a high rate of intracranial hemorrhage in patients with head injuries by Patrick G Hughes, Scott M Alter, Benjamin A Mazer, Joshua J Solano, Richard D Shih, Mary J Hughes, Lisa M Clayton, Spencer W Greaves, Nhat Q Trinh

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Pruritus in primary biliary cholangitis is under-recorded in patient medical records by Usha Gungabissoon, Haley S Friedler, John Logie, Jolyon Fairburn-Beech, Helen T Smith, Robyn von Maltzahn, Liyuan Ma, Dhirishiya P, Ashleigh McGirr, Jake N Hunnicutt, Christopher L Rowe, Meghan Tierney

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