Development and validation of the age-associated dementia policy (AgeD-Pol) computer simulation model in the USA and Europe by Anand Viswanathan, Lee H Schwamm, Krishna P Reddy, Emily P Hyle, Fatma M Shebl, Kenneth A Freedberg, Julia H A Foote, Yiqi Qian, Shibani S Mukerji, Nattanicha Wattananimitgul, Ankur Pandya

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Protocol for a process evaluation: face-to-face physiotherapy compared with a supported home exercise programme for the management of musculoskeletal conditions: the REFORM trial by David Wong, Catherine Sherrington, Manuela L Ferreira, Christopher G Maher, Hueiming Liu, Joshua R Zadro, Lisa A Harvey, Hannah G Withers, Joanne V Glinsky, Jackie Chu, Matthew D Jennings, Alison J Hayes, Ian J Starkey, Blake A Palmer, Lukas Szymanek, Jackson J Cruwys, Kitty Duong, Anne Barnett, Matthew J Tindall, Barbara R Lucas, Tara E Lambert, Deborah A Taylor

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Resuscitative endovascular balloon occlusion of the aorta in trauma management: a comprehensive study of clinical indications and challenges by Tongporn Wannatoop, Peerayuht Phuangphung, Tanut Sornmanapong

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Blockades of effector T cell senescence and exhaustion synergistically enhance antitumor immunity and immunotherapy by Xia Liu, Emily Shaw, Fusheng Si, Guangyong Peng, Yan Tao, Feiya Ma, David Bagley, Yuanqin Zhang

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Mortality of elder financial and psychological abuse victims in rural Malaysia: a prospective cohort study by Raudah Mohd Yunus, Farizah Hairi, Noran N Hairi, Wan Yuen Choo, Sajaratulnisah Othman, Rajini Sooryanarayana, Norliana Ismail, Sharifah Nor Ahmad, Inayah Abdul Razak, Devi Peramalah, Awang Bulgiba Awang Mahmud, Halima B Awang, Siti Zaharah Jamaludin, Jamali Samsuddin, Mohammad Mafrukhin Mokhtar, Syed Mohd Fauzi, Zainudin Mohd Ali

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Triple jump for the optimal management of psoriatic arthritis: diet, sleep and exercise – a review by Ennio Lubrano, Kurt de Vlam, Rik Lories, Silvia Scriffignano, Fabio Massimo Perrotta, Mario Ronga

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First-in-human dose escalation trial to evaluate the clinical safety and efficacy of an anti-MAGEA1 autologous TCR-transgenic T cell therapy in relapsed and refractory solid tumors by Ignacio I Wistuba, Mamta Kalra, Linus Backert, Martin Wermke, Edwin R Parra, Jason John Luke, Apostolia M Tsimberidou, Sebastian Bunk, Mohammad B Hossain, Andrea Mayer-Mokler, Arun Satelli, Norbert Hilf, Steffen Walter, Cedrik M Britten, Van K Morris, Tobias A W Holderried, Winfried H Alsdorf, Katrin Wetzko, Borje S Andersson, Sandra Grund-Gröschke, Katrin Aslan, Anantha Marisetty, Swapna Satam, Jens Hukelmann, M Alper Kursunel, Karine Pozo, Andreas Acs, Melissa Baumeister, Claudia Wagner, Oliver Schoor, Ali S Mohamed, Delfi Krishna

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Venous thromboembolism incidence and risk factors associated with immune checkpoint inhibitors among patients with advanced non-small cell lung cancer by Chi Nguyen, Alok A Khorana, John Barron, Jennell Palaia, Lisa Rosenblatt, Radhika Pisupati, Ning Huang, Kerrin Gallagher, T Christopher Bond

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Gastrointestinal symptoms and bowel habits in 53 046 healthy Danish blood donors: a nationwide cross-sectional study by Christian Erikstrup, Ole Birger Pedersen, Henrik Hjalgrim, Erik Sørensen, Jens Frederik Dahlerup, Klaus Rostgaard, Mikkel Steen Petersen, Sisse Rye Ostrowski, Susan Mikkelsen, Khoa Manh Dinh, Thorsten Brodersen, Janna Nissen, Anne Karmisholt Grosen, Jens Kjærgaard Boldsen, Simon Mark Dahl Baunwall, Mie Topholm Bruun, Bitten Aagaard, Christina Mikkelsen, Christian Lodberg Hvas

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Correlation between ellipsoid zone thickness and the presence of subretinal drusenoid deposits in age-related macular degeneration by Richard B Rosen, Roland Theodore Smith, Gerardo Ledesma-Gil, Oscar Otero-Marquez, Yuehong Tong, Katy Tai, Gareth M C Lema, Raymond Matthew Bellis, Yang Fei, Brandon Le

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Sustainable employability in Supported Employment and IPS interventions in the context of the characteristics of work and perspectives of the employers: a scoping review protocol by Pirjo Juvonen-Posti, Matti Joensuu, Joonas Poutanen, Kirsi Unkila

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Study protocol on risk factors for the diagnosis of gestational diabetes mellitus in different trimesters and their relation to maternal and neonatal outcomes (GDM-RIDMAN) by Khalida Ismail, Boon How Chew, Iliatha Papachristou Nadal, Angus Forbes, Nurul Iftida Basri, Rozita Zakaria, Pamela Phui Har Yap, Veronika Rysinova, Intan Nureslyna Samsudin, Nurain Mohd Noor, Ziti Akthar Supian, Haslinda Hassan, Fuziah Paimin, Siti Rohani Mohamed Alias, Norizzati Bukhary Ismail Bukhary, Madeleine Benton

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STING agonist-based treatment promotes vascular normalization and tertiary lymphoid structure formation in the therapeutic melanoma microenvironment by Walter J Storkus, Ronald J Fecek, Manoj Chelvanambi, Jennifer L Taylor

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Acceptance commitment therapy (ACT) for psychological distress associated with inflammatory bowel disease (IBD): protocol for a feasibility trial of the ACTforIBD programme by Richard Gearry, Matthew Fuller-Tyszkiewicz, Andrew McCombie, Peter Gibson, Simon Knowles, Lisa Olive, Antonina Mikocka-Walus, Subhadra Evans, Leanne Raven, Daniel Romano, Eric O, Madeleine Dober, Leesa van Niekerk, Susan Chesterman

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Non-pharmacological interventions for the reduction and maintenance of blood pressure in people with prehypertension: a systematic review protocol by Paul Rutter, Andrew Clegg, Valerio Benedetto, Caroline Watkins, Nefyn Williams, Joseph Spencer, Lucy Hives, Emma P Bray, Cath Harris, Rachel F Georgiou, Nafisa Iqbal

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Reinforcing cancer immunotherapy with engineered porous hollow mycobacterium tuberculosis loaded with tumor neoantigens by Jie Jiang, Feng-Ying Huang, Shu-Zhen Dai, Guang-Hong Tan, Ming-Hui Chen, Hengyu Chen, Wu-Ping Zheng, Ri-Hong Wu, Weijing Xie

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Assessing the feasibility of using publicly available data sources to identify healthcare data discrepancies and enhance service delivery: a retrospective cross-sectional study of... by Sheila Leatherman, Matthew Neilson, Alix Boisson-Walsh, Jack Lewis

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Does abortion increase women's risk for post-traumatic stress? Findings from a prospective longitudinal cohort study by M Antonia Biggs, Charles E McCulloch, Brenly Rowland, Diana G Foster

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Do doctors and other healthcare professionals know overdiagnosis in screening and how are they dealing with it? A protocol for a mixed methods systematic review by Ann Van den Bruel, An De Sutter, Stefan Heytens, Veerle Piessens, Ann Van Hecke

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Subscapular skinfold thickness, not other anthropometric and dual-energy X-ray absorptiometry-measured adiposity, is positively associated with the presence of age-related macular... by Jayne Woodside, David Wright, Margaret Rayman, Miguel Gedtal, Ruth Esther Hogg

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