Coexistence of Anti-GAD and Anti-GABAAR Antibodies in an Autoimmune Encephalitis Patient: A Case Report by Lu X, Wu H, Tan Y, Mao X

“…Coexistence of anti-glutamic acid decarboxylase (GAD) and anti-Gamma-aminobutyric acid-α-receptor (GABAAR) antibodies in AE was rare.Case Presentation: A 44-year-old female patient presented to our hospital due to cognitive decline for 4 years, seizures, slowed speech and depression for 2 months. …”
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Investigating the potential immunomodulatory effects of commercial oral probiotic supplements on equine gastrointestinal tract barrier function by Agnieszka Żak-Bochenek, Paulina Żebrowska-Różańska, Joanna Bajzert, Łukasz Łaczmański, Bogumiła Szponar, Natalia Siwińska, Klaudia Gładysz, Katarzyna Sikorska, Anna Chełmońska-Soyta

“…The concentrations of SCFAs, specifically acetic and propionic acids, significantly increased over time in both groups according to the generalized linear mixed effects (GLME) model. …”
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Inulin Reduces Kidney Damage in Type 2 Diabetic Mice by Decreasing Inflammation and Serum Metabolomics by Jiayuan He, Xiang Li, Man Yan, Xinsheng Chen, Chang Sun, Jiajun Tan, Yinsheng Song, Hong Xu, Liang Wu, Zhengnan Yang

“…Additionally, inulin treatment in mice with a T2DM model led to a significant increase in the concentrations of three primary short-chain fatty acids (SCFAs) (acetic acid, propionic acid, and butyric acid), while the concentration of advanced glycation end products (AGEs), a prominent inflammatory factor in diabetes, exhibited a significant decrease. …”
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Innovative determination of phytohormones in Aloe vera by Muhammad K. Hakeem, Meera Maraqa, Sampath K. Elangovan, Sampath K. Elangovan, Esam Eldin Saeed, Ajay Kumar Mishra, Khaled M. Hazzouri, Iltaf Shah, Iltaf Shah, Khaled M. A. Amiri

“…This study aims to develop and validate a sensitive method for the determination of six key phytohormones in Aloe vera using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).MethodsA validated LC-MS/MS method was optimized for the determination and quantification of six phytohormones in Aloe vera: Abscisic Acid (ABA), Salicylic Acid (SA), Indole-3-Acetic Acid (I3AA), Gibberellic Acid (GA), 6-Benzylaminopurine (6BAP), and Isopentenyladenine (ISA). …”
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Liquid Chromatographic–Mass Spectrometric Determination of Ezetimibe in Human Plasma With Validation Approach by Ahmed A. Alobaida

“…Results: Reconstituted samples were then chromatographed using 80:20, v/v combination of acetonitrile and ammonium acetate 5 mM as the mobile phase at a flow rate of 0.5 mL/min on a reversed-phase column (C18, 25 mm × 4.6 mm, 5 µm from Waters). …”
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Exploring the anticancer potential of Hewittia malabarica through phytochemical analysis and molecular docking study by Shiji Thozhukkad Moosaripparambil, Kannan Vadakkadath Meethal

“…An analysis of ADME properties of compounds obtained in GC-MS analysis of the chloroform extract showed that compounds such as Cyclododecanol, Sulfurous acid hexyl octyl ester, 2,4-Ditert-Butylphenol and 1,2-benzenedicarboxylic acid had favourable physicochemical and drug-likeness characteristics. …”
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Comparing the Efficacy of Local Corticosteroid Injection, Platelet-Rich Plasma, and Extracorporeal Shockwave Therapy in the Treatment of Pes Anserine Bursitis: A Prospective, Rando... by Wesam Gouda, Awad S. Abbas, Tarek M. Abdel-Aziz, Mohamed Z. Shoaeir, Walid Ahmed, Abdelhfeez Moshrif, Ahmed Mosallam, Mohamed Kamal

“…They were equally divided into three groups as follows: Group I received a local corticosteroid injection of 40 mg of methylprednisolone acetate/1 ml; Group II received a PRP injection; and in Group III, ESWT was used. …”
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Comprehensive evaluation of the properties of camel bone gelatin: impact of the duration of pre-treatment and extraction by Meriem Imelhayene, Abdelkader Adamou, Samira Becila, Ayad Redjeb, Dahia Saidj, Abdelhakim Senoussi, Dimitris Sarris, Eleni Naziri

“…The gelatin extraction process comprised demineralization with hydrochloric acid, followed by pre-treatment with sodium hydroxide for 24 or 48 hours and subsequent chemo-thermal extraction in acetic acid for 6 or 12 hours. …”
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Integrated metabolome and transcriptome analysis reveals potential mechanism during the bud dormancy transition of Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsi... by Huan Guan, Huan Guan, Yuhuan Zhao, Yuhuan Zhao, Qing Chen, Qianqian Zhang, Qianqian Zhang, Pengpeng Yang, Pengpeng Yang, Shuying Sun, Shuying Sun, Guilin Chen, Guilin Chen

“…During the transition from endo- to ecodormancy, the highest content of indole-3-acetic acid (IAA) and the highest number of DEGs enriched in the IAA signaling pathway demonstrated that IAA may play a key role in this process. …”
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Study on the Fingerprint Spectrum and the Spectrum-Effect Relationship of Analgesic and Anti-Inflammatory Effects of the Aqueous Extract from Dalbergia hancai Benth by Qin Qiu, Xiaofang Liu, Chunying Huang, Yanling Guo, Dandan Zhen, Junhao Shi, Baojun Gu, Hanshen Zhen, Miao Zhang

“…At the same time, similarity evaluation, cluster analysis, and principal component analysis (PCA) had also been conducted to evaluate the common peaks. The acetic acid-induced writhing in mice had been employed as an analgesic model, and the carrageenan-induced toe swelling in mice was utilized as an anti-inflammatory model for pharmacodynamic experiments. …”
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Gestion optimale des ressources forestières : application des modèles de Faustmann et du rendement maximal soutenu (RMS) : Cas du cèdre de l’Atlas by Abdelmoula Aalioua, Adnan Jermoun

“…L'objectif principal de ce travail est de déterminer combien de temps un exploitant forestier devrait-il attendre avant de procéder à l'abattage d'une parcelle de forêt abritant des arbres du même âge afin de maximiser son rendement financier. …”
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Elucidation of α-glucosidase inhibitory activity and UHPLC-ESI-QTOF-MS based metabolic profiling of endophytic fungi Alternaria alternata BRN05 isolated from seeds of Swietenia mac... by Piyush Kumar, Sai Anand Kannakazhi Kantari, Ranendra Pratap Biswal, Prasanth Ghanta, Malleswara Dharanikota

“…This study aims to explore and identify novel bioactive metabolites with anti-diabetes potential from Alternaria alternata BRN05, an endophytic fungus isolated from a well-known medicinal plant Swietenia macrophylla King. Ethyl acetate extracts of Alternaria alternata BRN05 grown in full-strength (EFS) and quarter-strength (EQS) media, respectively were evaluated for their α-glucosidase inhibitory activities. …”
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Antibacterial Effect of Luma apiculata (DC.) Burret Extracts in Clinically Important Bacteria by Tiare Araya-Contreras, Rhonda Veas, Carlos A. Escobar, Pamela Machuca, Mauricio Bittner

“…., hexane, methylene dichloride, ethyl acetate, ethanol, methanol, and water) to extract the compounds depending on their polarity. …”
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Crude Drugs for Clearing Heat Contain Compounds Exhibiting Anti-Inflammatory Effects in Interleukin-1β-Treated Rat Hepatocytes by Airi Fujii, Saki Onishi, Nodoka Watanabe, Mizuki Kajimura, Kentaro Ito, Keita Minamisaka, Yuto Nishidono, Saki Shirako, Yukinobu Ikeya, Mikio Nishizawa

“…In this study, the other crude drugs were extracted and partitioned with ethyl acetate (EtOAc) and <i>n</i>-butanol to obtain three crude fractions. …”
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Unraveling the depth-dependent causal dynamics of methanogenesis and methanotrophy in a high-latitude fen peatland by Shuai Yang, Jinyun Tang, Zhen Li, Kunxiaojia Yuan, Qiong Wu, Kuang-Yu Chang, Suzanne B Hodgkins, Rachel M Wilson, Qing Zhu, Robert F Grant, William J Riley, Scott R Saleska, Virginia I Rich, Ruth K Varner

“…Additionally, long-term in situ measurements within soil columns are limited and associated with large uncertainties in microbial substrates (e.g. dissolved organic carbon, acetate, hydrogen). To better understand CH _4 cycling dynamics, we first applied an advanced biogeochemical model, ecosys , to explicitly simulate methanogenesis, methanotrophy, and CH _4 transport in a high-latitude fen (within the Stordalen Mire, northern Sweden). …”
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Evaluation of Leea rubra Leaf Extract for Oxidative Damage Protection and Antitumor and Antimicrobial Potential by Nibedita Das, Sanowar Hossain, Jaytirmoy Barmon, Shahnaj Parvin, Mahadi Hasan, Masuma Akter, Ekramul Islam

“…Antitumor activity was assessed by evaluating the percentage inhibition of cell growth, morphological changes of Ehrlich’s ascites carcinoma (EAC) cells, and hematological parameters. …”
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Comparative Proteomics of Two Flor Yeasts in Sparkling Wine Fermentation: First Approach by Juan C. García-García, Teresa García-Martínez, Juan J. Román-Camacho, Juan Moreno, Juan C. Mauricio

“…Key protein data support the relationship between these differences, and the proteomic analysis could show that strain N62 had a higher abundance of proteins related to protein synthesis, such as PAB1, TEF2, and RPL25; DAK1, GPP1, and GPP2 are involved in glycerol synthesis and PDC6 and ALD4 in acetate synthesis. In the case of G1, the abundance of ADHI is associated with ethanol production and cell wall proteins with YGP1, EXG1, SCW11, PST1, CIS3, and PIR3, while the onset of autophagy is associated with PRC1, PRB1, ATG42/YBR139W, PRE8, PRE9, and PUP2.…”
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Collecting duct NCOR1 controls blood pressure by regulating mineralocorticoid receptor by Ke Sun, Yong-Li Wang, Chen-Chen Hou, Da Shang, Lin-Juan Du, Lan Bai, Xing-Yu Zhang, Chuan-Ming Hao, Sheng-Zhong Duan

“…Introduction: Nuclear receptor corepressor 1(NCOR1) is reported to play crucial roles in cardiovascular diseases, but its function in the kidney has remained obscure. …”
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<i>GsEXPA8</i> Enhances Soybean Tolerance of NaHCO₃ Stress by Regulating Root Morphology by Mengyu Liu, Jixiang Tang, Shengjie Ma, Yujing Liu, Xiaoyu Wang, Xinlei Du, Xiaohuan Sun, Yucheng Zeng, Yulong Zeng, Xiaodong Ding, Yingpeng Han, Junfeng Zhang, Lei Cao

“…Wild soybean was treated with abscisic acid (ABA), indole-3-acetic acid (IAA), gibberellic acid (GA), and jasmonic acid (JA), and <i>GsEXPA8</i> was found to respond to ABA and IAA signals. …”
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Antibiotic-mediated dysbiosis leads to activation of inflammatory pathways by Jemma J. Taitz, Jemma J. Taitz, Jian Tan, Jian Tan, Duan Ni, Duan Ni, Camille Potier-Villette, Camille Potier-Villette, Georges Grau, Georges Grau, Ralph Nanan, Ralph Nanan, Ralph Nanan, Laurence Macia, Laurence Macia, Laurence Macia

“…Epidemiological analysis revealed a positive correlation between global antibiotic consumption and IBD incidence.DiscussionOur findings demonstrate that antibiotic-mediated dysbiosis results in significantly altered short-chain fatty acid levels but immune homeostasis in spleen and MLNs at steady state is mostly preserved. …”
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