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3881
Unlocking the multifaceted roles of GLP-1: Physiological functions and therapeutic potential
Published 2025-06-01“…The intricate molecular mechanisms underlying GLP-1RAs are explored, including their interactions with pathways like extracellular signal-regulated kinase 1/2 (ERK1/2), activated protein kinase (AMPK), cyclic adenine monophosphate (cAMP), mitogen-activated protein kinase (MAPK), and protein kinase C (PKC). …”
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3882
Copy number amplification of FLAD1 promotes the progression of triple-negative breast cancer through lipid metabolism
Published 2025-02-01“…Through an integrated analysis of our TNBC multiomic dataset (n = 465) and subsequent experimental validation, we identify copy number amplification of the metabolic gene flavin-adenine dinucleotide synthetase 1 (FLAD1) as a crucial genetic event that drives TNBC progression. …”
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3883
Evaluation of Clinical and Immunological Characteristics of Children with Common Variable Immunodeficiency
Published 2018-01-01“…Two patients presented with autoimmune thrombocytopenia and anemia, and one patient exhibited lung empyema. All the patients had immunoglobulin G deficiencies. …”
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3884
Weighted fuzzy C means and enhanced adaptive neuro-fuzzy inference based chronic kidney disease classification
Published 2024-03-01“…Numerous complications, such as elevated blood levels, anemia, weak bones, and nerve damage, constitute a problem. …”
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3885
A Case of Significant Response to Olaparib in a Patient with Primary Peritoneal Carcinosarcoma Diagnosed by Laparoscopic Surgery
Published 2020-01-01“…Although a dose reduction was needed due to anemia, olaparib was effective, and the patient could continue the drug for another 7 months. …”
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3886
Generalized Demodicosis and Malasseziosis in a Pug Mix Dog
Published 2023-09-01“…The skin tape examination revealed an infestation of Demodex sp. mites accompanied by Malassezia sp. hematological analysis indicated that the dog presented anemia. The dog was diagnosed with demodicosis with a secondary infection of Malassezia sp. …”
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3887
Tax convergence within economic integration frameworks: Post-COVID trajectories
Published 2024-10-01“…In the study, we explore the convergence hypothesis in relation to the tax systems of a group of post-Soviet countries: Armenia, Belarus, Kazakhstan, Kyrgyzstan, and Russia. …”
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3888
Metáforas de la(s) revuelta(s) en la narrativa chilena reciente
Published 2025-01-01“…En líneas generales, el corpus está integrado por un conjunto de novelas que, desde propuestas estéticas diferentes, articulan una serie de metáforas que aluden a una crisis generalizada del modelo político y económico predominante e inscriben en el presente la memoria de los crímenes cometidos por la dictadura militar: Avenida 10 de Julio (2022) de Nona Fernández, Sumar (2018) de Diamela Eltit, Satancumbia (2020) de Rodrigo Miranda y La orquesta imaginaria (2021) de Rodrigo Díaz Cortez. …”
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3889
Impact of nutritional screening on mortality and intensive care unit length of stay
Published 2025-02-01“…Furthermore, there was a greater presence of enteral support, diarrhea, anemia, leukocytosis, and lymphopenia in this cohort.ConclusionImplementing the MUST screening method and specific nutritional interventions resulted in a significant improvement in patient mortality figures. …”
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3890
The Utility of Fecal Calprotectin in the Real-World Clinical Care of Patients with Inflammatory Bowel Disease
Published 2016-01-01“…Positive FCAL was associated with colonoscopy findings of active IBD (P<0.05), low albumin (P<0.05), anemia (P<0.01), and elevated CRP (P<0.01). There was no significant difference for FCAL results by outcomes on small bowel evaluation among the 21 persons with small bowel CD. …”
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3891
Brucellosis Presenting with Febrile Pancytopenia: An Atypical Presentation of a Common Disease and Review of Brucellosis
Published 2021-01-01“…A presumptive diagnosis is typically established through correlation of patient history and classic laboratory findings, which include transaminitis, anemia, and leukopenia with relative lymphocytosis. …”
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3892
Characteristics of Pediatric Crohn’s Disease in Saudi Children: A Multicenter National Study
Published 2016-01-01“…Laboratory findings revealed anemia in 57.9% of patients, low albumin in 34.5%, and high CRP in 39.4%. …”
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3893
Hemolysis, Elevated Liver Enzymes, and Low Platelets, Severe Fetal Growth Restriction, Postpartum Subarachnoid Hemorrhage, and Craniotomy: A Rare Case Report and Systematic Review
Published 2017-01-01“…The syndrome itself is manifested by hemolytic anemia, increased liver enzymes, and decreasing platelet counts with a majority of neurological defects resulting from hemorrhagic stroke or subarachnoid hemorrhage (SAH). …”
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3894
Postnatal Growth Patterns in a Chilean Cohort: The Role of SES and Family Environment
Published 2012-01-01“…We studied 999 infants, born between 1991 and 1996, from a longitudinal cohort which began as an iron deficiency anemia preventive trial. SES (Graffar Index), the Life Experiences Survey, and the Home Observation for Measurement of the Environment (HOME) were assessed in infancy. …”
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3895
An Immunocompetent HIV-Negative Elderly Patient with Low-Grade Fever, Generalized Lymphadenopathy, Splenomegaly, and Acute Phase Response: Do Not Forget Castleman Disease
Published 2021-01-01“…Laboratory findings showed anemia and increased markers of inflammation including hyperferritinemia and polyclonal hyperglobulinemia. …”
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3896
Conversion of Low-Flow Priapism to High-Flow State Using T-Shunt with Tunneling
Published 2017-01-01“…Case 1 was a 33-year-old male with sickle cell anemia and case 2 was a 24-year-old male with idiopathic thrombocytopenic purpura. …”
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3897
Machado-Joseph Disease, A Case Report of Treatment Based on Phototherapy
Published 2024-11-01“…Machado-Joseph disease (MJD) is a rare autosomal dominant disease caused by a mutation in exon 10 of the ATXN3 gene resulting from a cytosine-adenine-guanine trinucleotide repeat. A case of a 48-year-old man with MJD is reported. …”
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3898
Educomunicação: caminhos de transformação nas práticas e políticas sociais
Published 2024-12-01“…A partir do referido resgate, destaca-se que a fala e a escuta atenta, o senso comunitário, a educação transversal e a liberdade de expressão, inerentes à práxis educomunicativa, garantem a legitimação do conceito, fortalecendo a Educomunicação enquanto campo que promove a mobilização e a transformação social em prol do exercício da cidadania, da democracia e da garantia dos direitos. …”
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3899
Effect of Amaranth-Containing Dietary Intervention in Improving Hemoglobin Concentration: A Systematic Review and Meta-Analysis
Published 2025-01-01“…ObjectiveAmaranth, a nutritious iron source, is known for treating anemia in young children and lactating mothers, but its effectiveness in reducing hemoglobin concentration needs further investigation. …”
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3900
Lipidomics of Huntington’s Disease: A Comprehensive Review of Current Status and Future Directions
Published 2025-01-01“…Despite a limited understanding of its pathogenesis, research has implicated abnormal trinucleotide cytosine-adenine-guanine CAG repeat expansion in the huntingtin gene (HTT) as a critical factor. …”
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