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19761
Osteoblast‐Derived ECM1 Promotes Anti‐Androgen Resistance in Bone Metastatic Prostate Cancer
Published 2025-01-01“…This event further recruits adapter proteins including growth factor receptor‐bound protein 2 (GRB2) and son of sevenless homolog 1 (SOS1), which activates the downstream mitogen‐activated protein kinase (MAPK) signaling pathway to induce anti‐androgen resistance. …”
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19762
Enhanced Lithographic Hotspot Detection via Multi-Task Deep Learning With Synthetic Pattern Generation
Published 2025-01-01“…Our key contributions include: (1) A synthetic pattern generation method based on early design space exploration (EDSE) to augment training data and improve TNSB hotspot detection; (2) A multi-task convolutional neural network architecture that jointly performs hotspot classification and localization; and (3) An adaptive loss function that balances hotspot detection accuracy and false alarm reduction. …”
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19763
PPARγ and the Innate Immune System Mediate the Resolution of Inflammation
Published 2015-01-01“…There are also roles for this receptor in the adaptive immune response, particularly regarding B cells. …”
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19764
Attraction and aversion of noctuid moths to fermented food sources coordinated by olfactory receptors from distinct gene families
Published 2025-01-01“…Conclusions Our findings suggest that this functional conservation is an olfactory adaptation that has allowed noctuid moths to extend their diet to fermented food sources.…”
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19765
Operational Protocol for Prosthetically Guided Reconstruction of Edentulous Sites Using a Custom-Made Technique
Published 2024-12-01“…The custom-made membranes, which were designed based on the individual defects, exhibited successful adaptation. Surgical phases involved membrane placement, bone grafting, and subsequent implant placement. …”
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19766
Identifying the Aesthetic Criteria of Academic Library Websites Using a Delphi Panel
Published 2024-11-01“…While designed for Iranian websites, the results are adaptable to other cultural contexts. The study contributes significantly to the field by providing a comprehensive tool for website evaluation and emphasizing the need for culturally nuanced designs.Value: This research is the first in Iran to apply a Delphi approach for identifying aesthetic website criteria, contributing significantly to the global understanding of web aesthetics in academic contexts.…”
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19767
Kadrolu ve 4/B Sözleşmeli YardımcıSağlık Personellerinin İşDoyumlarının Karşılaştırılması
Published 2013-02-01“…Bu bağlamda araştırmanın amacı, kamu sağlık hizmetleri sektöründe istihdam edilen 657 sayılıDMK’na tabi kadrolu ve 4/B sözleşmeli hekim dışıyardımcısağlık personellerinin işdoyumlarınıkarşılaştırmaktır. …”
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19768
HANS REICHENBACH’IN BİLİMSEL FELSEFESİ: BULMA VE DOĞRULAMA BAĞLAMLARI ÜZERİNDEN BİR DEĞERLENDİRME
Published 2023-12-01“…Bu makalede, Reichenbach’ın bulma ve doğrulama bağlamları arasında ne tür bir ayrım yaptığı irdelenmek suretiyle onun bilimsel felsefesini nasıl temellendirdiği açıklanmaya çalışılacaktır. Bu makalenin amacı, düşünürün özellikle Experience and Prediction ve Bilimsel Felsefenin Doğuşu adlı eserlerinde ortaya koyduğu görüşlerini yeniden hatırlatarak bulma ve doğrulama bağlamlarına yönelik ayrımın içeriğini hem meseleyi benzer şekilde ele alanların hem de konuya eleştirel yaklaşanların katkıları ekseninde çözümlemektir.…”
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19769
Smart furniture using radar technology for cardiac health monitoring
Published 2025-01-01“…Radar technology’s inherent non-contact methodology, privacy-preserving features, adaptability to diverse environmental conditions, and high precision characteristics collectively establish it a compelling alternative for comprehensive health monitoring within domestic environments. …”
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19770
Eski Mardin’de Bir Mikro-Tarih Anlatısı: Çamurdaş Evi
Published 2021-04-01“…Çoğunlukla ‘yeni’ kentin görece konforlu konutlarında yaşamak için ve turizm odaklı restorasyon süreçleri yüzünden terk edilen bu yapılarda ‘geçmişte nasıl yaşandığı’, sadece nostalji temelli ve sınırlı bir anlatı olarak bilinmektedir. Bu çalışmanın amacı, Mardin kültür envanterinde yer alan, günümüzde Çamurdaş ailesinin yaşadığı Artuklu İlçesi Şehidiye Mahallesi numara 130’da bulunan konutun tarihselliğini, gündelik hayat pratikleri ve mekansal kullanımları üzerinden tartışmaktır. …”
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19771
Improvement of Soybean Oil Solvent Extraction through Enzymatic Pretreatment
Published 2012-01-01“…The purpose of this study is to evaluate multienzyme hydrolysis as a pretreatment option to improve soybean oil solvent extraction and its eventual adaptation to conventional processes. Enzymatic action causes the degradation of the cell structures that contain oil. …”
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19772
Covid-19 Salgınının İşletmelerin Finansal Başarısızlığı Üzerine Etkileri: BİST İmalat Sektöründe Yer Alan İşletmelerin Altman Z-Skor Yöntemi Kullanılarak İncelenmesi...
Published 2022-09-01“…Bu çalışmada Borsa İstanbul (BİST) İmalat Sektöründe yer alan işletmelerin COVİD-19 salgınından nasıl etkilendiği tespit edilmeye çalışılmıştır. Çalışmanın amacı; BİST İmalat Sektöründe yer alan işletmelerin Altman Z’’’-Skor yöntemiyle iflas riski oranlarını hesaplayarak, bu oranlardaki iki yıllık çeyrek dönemler itibariyle meydana gelen değişimleri COVİD-19 salgını ile ilişkilendirerek yorumlamaktır. …”
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19773
Analysis of the Impact of Using a Gamified App for Spanish Spelling Practice in Primary Education
Published 2025-01-01“…Discussion centered on the benefits of integrating gamification and ubiquitous learning tools in education, emphasizing the app’s adaptability and immediate feedback, which encouraged independent learning and sustained motivation. …”
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19774
Dual Strategy Based Improved Swarm Intelligence and Stacked LSTM With Residual Connection for Land Use Land Cover Classification
Published 2025-01-01“…The dual strategy includes adaptive inertia weight and phasor operator strategy to select relevant features from the feature subset. …”
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19775
Regulation of Stress-Induced Immunosuppression in the Context of Neuroendocrine, Cytokine, and Cellular Processes
Published 2025-01-01“…A significant portion of the data confirms that the activation of the hypothalamic–pituitary–adrenal (HPA) axis and subsequent elevation of cortisol levels exert substantial immunosuppressive effects on immune cells, particularly macrophages and lymphocytes, leading to the suppression of innate and adaptive immune responses. The data also highlight the crucial role of cortisol and catecholamines (adrenaline and noradrenaline) in initiating immunosuppressive mechanisms under chronic stress.…”
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19776
The moderating role of self-efficacy on the cognitive process of entrepreneurship: An empirical study in Vietnam
Published 2021-01-01“…Specifically, this study explores the moderating effects of entrepreneurial self-efficacy on the relationships between attitude towards entrepreneurship, subjective norms, perceived behavioral control, and intention to become entrepreneurs. Methodology: By adapting the theory of planned behavior and using data collected from 2218 students in Vietnam, the author utilizes a meta-analytic path analysis in order to show that entrepreneurial intention is strongly influenced by attitude towards entrepreneurship, followed by self-efficacy and perceived behavioral control. …”
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19777
Automated and virus variant-programmable surrogate test qualitatively compares to the gold standard SARS-CoV-2 neutralization assay
Published 2024-12-01“…Abstract The ongoing emergence of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants underscores the need for rapid, adaptable, high-throughput testing. However, assays for neutralizing antibodies, which are a good measure of viral protection, usually require cell culture and either infectious SARS-CoV-2 or pseudotyped viral particles. …”
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19778
Yeni Medyada, Dijital Tasarım Disiplinleri: Tanımları, Ortaklıkları ve Eğitim Programları
Published 2024-12-01“…Çünkü geleneksel medya denilince akla ilk gelen, grafik tasarım disiplinidir ve dijitalleşme sürecinde kendini uyumlandırarak, yeni medyanın ihtiyaçlarına yanıt vermiştir. Bu makalenin amacı, grafik tasarımla beraber, günümüz yeni medyasında aktif rol oynayan dijital tasarım disiplinlerinin tanımlarını, eğitim anlayışını, iş olanaklarını ve birbirleriyle ortak noktalarını ortaya koyarak anlam karmaşasını azaltmaktır. …”
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19779
Zirvedeki Türk İşletmelerinin Kurumsal Sosyal Sorumluluk İletişimi: Web Sitelerine Yönelik Bir İnceleme
Published 2013-11-01“…İnternet kısa süre içerisinde, vazgeçilemez bir iletişim aracı haline gelmiştir. Bu nedenle, kurumsal web sitelerinin önemi ve kurumsal sorumluk açısından verilecek olan bilgiler bu çalışmada tartışmaya açılmıştır.…”
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19780
PILOT STUDY REGARDING AN ONLINE METHOD FOR DENTAL RADIOLOGY STUDENTS’ ASSESEMENT EXPERIMENTALLY APPLIED DURING THE 2020 PANDEMIC
Published 2024-12-01“…The Department of Dental Radiology (UMF Carol Davila) implemented an online experimental method to examine the radiological knowledge of the students, adapted to the context of the SARS COV 19 pandemic. …”
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