Multimedia: multimodal mediation analysis of microbiome data by Hanying Jiang, Xinran Miao, Margaret W. Thairu, Mara Beebe, Dan W. Grupe, Richard J. Davidson, Jo Handelsman, Kris Sankaran

“…We designed the multimedia R package to make advanced mediation analysis techniques accessible, ensuring that statistical components are interpretable and adaptable. The package provides a uniform interface to direct and indirect effect estimation, synthetic null hypothesis testing, bootstrap confidence interval construction, and sensitivity analysis, enabling experimentation with various mediator and outcome models while maintaining a simple overall workflow. …”
Get full text

Unraveling the transcriptomic effects of leucine supplementation on muscle growth and performance in basketball athletes. by Sinan Wang, Weishuai Guo, Rui Dong

“…These results suggest that leucine enhances muscle adaptation by regulating cytoskeletal dynamics, providing molecular insights into its role in improving athletic performance.…”
Get full text

Naming the untouchable – environmental sequences and niche partitioning as taxonomical evidence in fungi by Faheema Kalsoom Khan, Kerri Kluting, Jeanette Tångrot, Hector Urbina, Tea Ammunet, Shadi Eshghi Sahraei, Martin Rydén, Martin Ryberg, Anna Rosling

“…Soil fungal communities are shaped by environmental filtering and competitive exclusion so that closely related species are less likely to co-occur in a niche if adaptive traits are evolutionarily conserved. In soil profiles, distinct vertical horizons represent a testable niche dimension, and we found significantly differential distribution across samples for a well-supported pair of sister species hypotheses. …”
Get full text

Advances in the pilot point inverse method: Où En Sommes-Nous maintenant? by White, Jeremy, Lavenue, Marsh

“…This paper will review the advancements and adaptations of the PPM over the last two decades which have led to its ubiquity. …”
Get full text

Mapping the future: The current landscape and future directions of evidence-based practice in Saudi radiology departments. by Walaa Alsharif, Faisal Alrehily, Fahad H Alhazmi, Awadia Greeballah, Abdulaziz A Qurashi, Shrooq Aldahery, Adnan Alahmadi, Amirah Alsaedi, Sultan Alshoabi, Khalid M Alshamrani, Awatif M Omer, Raghad Aljuhani

“…<h4>Conclusion</h4>This study underscores the need for comprehensive education, ongoing training and a supportive organisational culture to enhance EBP adaption.…”
Get full text

The impact of anticoagulant-related bleeding on quality of life: Development of a novel measure based on perspectives from older adults. by Anna L Parks, Stacey L Slager, Amy M Cizik, Margaret C Fang, Mark A Supiano, Patti P Katz, Daniel M Witt

“…., specific bleeding symptoms, adaptations in relationships, fatigue) that fell into 5 domains: 1) bleeding symptoms, 2) healthcare experiences, 3) social function, 4) emotional function, 5) physical function. …”
Get full text

Studying yield components and attractions indices in common bean (Phaseolus vulgaris L.) accessions in the Northern Zone of the Volga-Akhtuba Floodplain by A. P. Ivakin, A. A. Grushin

“…In this regard, a vital breeding trend for common bean in this country is still the development of new cultivars, more high-yielding and adapted to various areas of cultivation. To solve this problem, an advanced science-based search for breeding sources is required. …”
Get full text

Prevalence and associated factors of healthy aging among community-dwelling older adults in Lishui city, China: a cross-sectional study by Jian-Hua Chen, Norhasmah Mohd Zain, Azlina Yusuf, Bi-He Ying

“…A validated questionnaire of Healthy Aging Instruments (HAI), Basic Psychological Needs Satisfaction (BPNS), Patient Health Questionnaire (PHQ-9), Ascertain Dementia 8 questionnaire (AD8), Family Adaption Scale (FAS), Community-Based Health Promotion Activity Questionnaires (HPAQ), Social Function Questionnaire for Chinese Older Adults (SFQCOA), Adult Health Self-Management Skills (ability) Rating Scale (AHSMSRS) was incorporated. …”
Get full text

The Cost-effectiveness of Celecoxib versus Non-steroidal Anti-inflammatory Drugs plus Proton-pump Inhibitors for Treating Osteoarthritis in Algeria by Nadir Hammoumraoui, Sid Ahmed Kherraf, Joaquin Mould-Quevedo, Tarek A. Ismail

“…**Methods:** The National Institute for Health and Clinical Excellence (NICE) health economic model from UK, updated with relative risks of adverse events using CONDOR trial data, was adapted for costeffectiveness analysis in OA patients aged ≥65 years. …”
Get full text

Determinants of children ever born among ever-married women in Bangladesh: evidence from the Demographic and Health Survey 2017–2018 by Atikur Rahman, Zakir Hossain, Mohammad Lutfor Rahman, Enamul Kabir

“…Mixed logistic regression modelling approach for binary responses was adapted to accommodate clustering effects via the generalised linear mixed model framework.Participants The study is based on 15 924 ever-married women in BDHS 2017–2018 (14 119 in BDHS 2014) of Bangladesh.Results As per the latest BDHS 2017–2018, 42.1% of reproductive women had three or more children. …”
Get full text

Analysis of Adverse Pregnancy Outcomes of Pregnant Women with Syphilis and Maternal-Infant Serological Association in Changzhou, China, 2015–2019 by Chaorong Bian, Zhiqiang Qin, Jieying Zhang, Mengtao Sun, Manman Gu, Kejin Chen

“…High-quality prenatal care is a key component in interrupting mother-to-child transmission of syphilis and preventing various adverse pregnancy outcomes. The adaptation of standardized treatment protocols for pregnant women with syphilis in China is a strong proof of the progress of precision medicine.…”
Get full text

An online intervention relationship enhancement couple therapy program versus systematic desensitization on sexual performance anxiety in women undergoing infertility treatment wit... by Maryam Afzal Dehkordi, Tahmineh Farajkhoda, Mahdi Khanabadi, Farimah Shamsi

“…RECT (couple relationship-centered) by empowering 10 interpersonal skills, and SD (personal-oriented) by learning step-by-step how fight-or-flight response is replaced by relaxation response, helping women perform more adaptive behaviors regarding sexual anxiety. RECT increased spouse satisfaction significantly compared to SD, indicating that males need to participate in positive relationship changes. …”
Get full text

Simulation of Flow Around a Finite Rectangular Prism: Influence of Mesh, Model, and Subgrid Length Scale by Xutong Zhang, Maxime Savoie, Mark K. Quinn, Ben Parslew, Alistair Revell

“…Numerical predictions from the RANS models were generally quite reasonable but did not show improvement with further refinement, as one would expect, whereas DDES clearly demonstrated continuous improvement in predictive accuracy with progressive mesh refinement. The shear-layer-adapted (SLA) subgrid length scale (<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mo>Δ</mo><mi>SLA</mi></msub></semantics></math></inline-formula>) displayed consistently superior performance compared to the more widely used length scale based on local cell volume, particularly for moderate mesh resolutions commonly employed in industrial settings with limited resources. …”
Get full text

Supporting self-management for patients with Interstitial Lung Diseases: Utility and acceptability of digital devices. by Malik A Althobiani, Rebecca Shuttleworth, John Conway, Jonathan Dainton, Anna Duckworth, Ana Jorge Da Ponte, Jessica Mandizha, Joseph W Lanario, Michael A Gibbons, Sarah Lines, Chris J Scotton, John R Hurst, Joanna C Porter, Anne-Marie Russell

“…We sought to quantify patients' usage and experiences with home digital devices, and further evaluate their perceived utility and barriers to adaptation.<h4>Methods</h4>A team of expert clinicians and patient partners interested in self-management approaches designed a 48-question cross-sectional electronic survey; specifically targeted at individuals diagnosed with ILD. …”
Get full text

Regional modeling of surface solar radiation, aerosol, and cloud cover spatial variability and projections over northern France and Benelux by G. Chesnoiu, I. Chiapello, N. Ferlay, P. Nabat, M. Mallet, V. Riffault

“…Our analysis relies on the National Centre for Meteorological Research–Limited Area Adaptation Dynamic International Development v6.4 (CNRM-ALADIN64) regional climate model at 12.5 km resolution, which includes an interactive aerosol scheme. …”
Get full text

The WF1 (White Flower 1) gene controlling the white color of petals and flowering time in lines from a mapping population of flax (Linum usitatissimum L.) by N. B. Brutch, I. I. Matvienko, E. A. Porokhovinova, A. V. Pavlov

“…Flax (Linum usitatissimum  L.) is grown  in different  climatic zones  as both  a spring  and  winter  crop. Adaptation to different growing conditions produced genotypes with different growth  durations and degrees of photosensitivity. …”
Get full text

Evaluation of Nutritional and Antinutritional Properties of African Yam Bean (Sphenostylis stenocarpa (Hochst ex. A. Rich.) Harms.) Seeds by Taofeek T. Adegboyega, Michael T. Abberton, AbdelAziz H. AbdelGadir, Mahamadi Dianda, Busie Maziya-Dixon, Olaniyi A. Oyatomi, Sam Ofodile, Olubukola O. Babalola

“…In sub-Saharan Africa, this lesser-known legume could be adapted as a promising food crop in combating protein-energy malnutrition.…”
Get full text

The global energy challenge: second-generation feedstocks on marginal lands for a sustainable biofuel production by Claudio Russo, Valerio Cirillo, Nausicaa Pollaro, Fabio Terribile, Andrea Chiodini, Albino Maggio

“…In this context, it becomes a priority to select biofuel crops with high productivity on marginal lands and pronounced resilience and adaptability traits. Underutilized crops such as Carthamus tinctorius, Ricinus communis, Brassica carinata, Camelina sativa etc. may fit the purpose and may represent a valuable alternative to first-generation feedstock because they require minimal agronomical input. …”
Get full text

Specificity of psychological readiness for changes and personality’s maturity of the employees of the state criminal and executive service by O. V. Mitroshkina

“…Hull (translation and adaptation by N. A. Bazhanova and G. L. Bardier) and the questionnaire of personal maturity (O. …”
Get full text

“A one-stop shop”: Real-world use and app-users' experiences of a psychoeducational smartphone app for adults with ADHD by Christina Seery, Rachel Hannah Cochrane, Martha Mulcahy, Ken Kilbride, Margo Wrigley, Jessica Bramham

“…‘Recommendations for ADHD-friendly adaptations’ identified modifications to improve usability of the app. …”
Get full text