Subcutaneous sarilumab for the treatment of hospitalized patients with moderate to severe COVID19 disease: A pragmatic, embedded randomized clinical trial. by Westyn Branch-Elliman, Ryan Ferguson, Gheorghe Doros, Patricia Woods, Sarah Leatherman, Judith Strymish, Rupak Datta, Rekha Goswami, Matthew D Jankowich, Nishant R Shah, Thomas H Taylor, Sarah T Page, Sara J Schiller, Colleen Shannon, Cynthia Hau, Maura Flynn, Erika Holmberg, Karen Visnaw, Rupali Dhond, Mary Brophy, Paul A Monach

“…<h4>Importance and objective</h4>The aim of this pragmatic, embedded, adaptive trial was to measure the effectiveness of the subcutaneous anti-IL-6R antibody sarilumab, when added to an evolving standard of care (SOC), for clinical management of inpatients with moderate to severe COVID-19 disease.…”
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Transgressive hybrids as hopeful holobionts by Benjamin Thomas Camper, Andrew Stephen Kanes, Zachary Tyler Laughlin, Riley Tate Manuel, Sharon Anne Bewick

“…In extreme cases, the effects of hybridization can transcend ecological timescales by introducing trait novelty upon which evolution can act. Indeed, hybridization can even have macroevolutionary consequences, for example, as a driver of adaptive radiations and evolutionary innovations. …”
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Efecto de la pandemia en la cirugía radical del cáncer vesical by Jorge Salgado-Novoa, Dario Vázquez-Martul, Susana Rodríguez-Rey, Ana M. Fandiño-Argibay, Arlene Rodríguez-González, Alicia López-Fernández, Venancio Chantada-Abal

“…Por su historia natural, el c&aacute;ncer vesical susceptible de cistectom&iacute;a radical (CR) requiere especial atenci&oacute;n. …”
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INNOVATIVE METHODS OF TEACHING HISTORY AT MODERN UNIVERSITIES by A. Yu. Suslov, M. V. Salimgareev, Sh. S. Khammatov

“…The recom mendations have universal character and can be used by teachers of other disciplines after applying specific content adaptation.…”
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Digestibility of pre-treated cassava peel as feed ingredient for Nile tilapia by , Mulyasari, Feri Kurniawati, Mia Setiawati

“…Feces collection started after five days of adaptation to chromium oxide diets. The results showed that the three treatments had significant effects compared to control (P<0.05), protein digestibility of were improved 5%, 15%, and 10%, energy digestibilitiy were 20%, 18%, 16%, and total digestibility of test cassava peel were 174%, 151%, and 164%, respectively. …”
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Conditional diffusion-generated super-resolution for myocardial perfusion MRI by Changyu Sun, Changyu Sun, Neha Goyal, Yu Wang, Darla L. Tharp, Senthil Kumar, Talissa A. Altes

“…While techniques like parallel imaging and compressed sensing have significantly advanced perfusion imaging, they still suffer from noise amplification, residual artifacts, and potential temporal blurring due to the rapid transit of dynamic contrast vs. the temporal constraints of the reconstruction.MethodsThis study introduces a conditional diffusion-based generative model for myocardial perfusion MRI super resolution, addressing the trade-offs between spatiotemporal resolution and slice coverage. We adapted Denoising Diffusion Probabilistic Models (DDPM) to enhance low-resolution perfusion images into high-resolution outputs without requiring temporal regularization. …”
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Taenia solium taeniosis and cysticercosis literature in Tanzania provides research evidence justification for control: A systematic scoping review. by Helena Aminiel Ngowi, Andrea Sylvia Winkler, Uffe Christian Braae, Robinson Hammerthon Mdegela, Ernatus Martin Mkupasi, Mwemezi Lutakyawa Kabululu, Faustin Peter Lekule, Maria Vang Johansen

“…In addition, locally adapted management guidelines for people suffering from NCC are urgently needed.…”
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The use of bacterial culture for Leptospirosis di- agnosis in female water buffaloes by Rosaura Pérez-Gil, Oriana Gavidia, Juan Torres

“…However, the low antibody titers in chronic infections induced by strains adapted to bovines can limit the interpretation of the correct results. …”
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Direct and moderation effects on U.S. apparel manufacturers’ engagement in network ties by Nancy J. Miller, Carol Engel-Enright, David A. Brown

“…Entrepreneurs’ interested in building domestic and international supply chain ties may find network ties provide one solution for adapting the firm’s resources for global competitiveness. …”
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Comparing the Technological and Intraoperative Performances of Da Vinci xi and DaVinci 5 Robotic Platforms in Patients Undergoing Robotic-Assisted Radical Prostatectomy by Ahmed Gamal, Marcio Covas Moschovas, Shady Saikali, Sumeet Reddy, Yu Ozawa, Rohan Sharma, Avaneesh Kunta, Travis Rogers, Vipul Patel

“…With this new platform, we maintained our conventional technique without any modifications or adaptions from the trocar placement until anastomosis. …”
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Analisis dan Perbaikan Proses Bisnis Sistem Terintegrasi Pembayaran Uang Kuliah dengan Metode Business Process Improvement (BPI) pada Universitas X by Ni Wayan Emmy Rosiana Dewi, Putu Yogie Ayu Nirmala, I Made Suwija Putra, A.A. Kompiang Oka Sudana

“…This is because some business processes do not yet have a goal to make it more effective, efficient, and easily adapted to other processes in the system. It is necessary to improve systems and business processes that produce business process recommendations to solve these problems. …”
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Response of Natural Forests and Grasslands in Xinjiang to Climate Change Based on Sun-Induced Chlorophyll Fluorescence by Jinrun He, Jinglong Fan, Zhentao Lv, Shengyu Li

“…This study provides an important scientific basis for ecological management and climate adaptation in Xinjiang, emphasizing the need for differentiated strategies across ecological regions to support sustainable development.…”
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Mise en oeuvre d’une politique pour une génération sans tabac au Canada : estimation des répercussions à long terme by Doug Coyle

“…MethodsUn modèle canadien antérieur pour l’arrêt de l’usage du tabac a été adapté et amélioré pour évaluer les répercussions d’une PGST sur les années de vie ajustées en fonction de la qualité (AVAQ), l’espérance de vie, les coûts des soins de santé, les taxes sur le tabac et le produit intérieur brut (PIB) de l’industrie canadienne du tabac. …”
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Genetic profiling of multidrug-resistant Acinetobacter baumannii from a tertiary care center in Malaysia by Aisyah Syakirah Shahari, Navindra Kumari Palanisamy, Fadzilah Mohd Nor

“…These STs are associated with acquired blaOXA-23, indicating an evolutionary adaptation of A. baumannii within the hospital setting.IMPORTANCEAcinetobacter baumannii is a ubiquitous Gram-negative coccobacillus bacterium that is primarily associated with nosocomial infections that can colonize biotic and abiotic surfaces to enhance cell-to-cell adhesion, ensuring the establishment of infections. …”
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Improving Visual Field Awareness among Collegiate Softball Athletes: A Randomized Trial by Diana R. Feldhacker, Whitney Lucas Molitor

“…The results from this study demonstrate the adaptability of the visual system for those with normal field of vision.…”
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An App-Based Intervention With Behavioral Support to Promote Brisk Walking in People Diagnosed With Breast, Prostate, or Colorectal Cancer (APPROACH): Process Evaluation Study by Fiona Kennedy, Susan Smith, Rebecca J Beeken, Caroline Buck, Sarah Williams, Charlene Martin, Phillippa Lally, Abi Fisher

“…Behavioral support calls were recorded, and the fidelity of delivery of 25 planned behavior change techniques was rated from 0 to 5 using an adapted Dreyfus scale. Mechanisms of impact were identified by examining T0 and T1 scores on the Self-Reported Behavioural Automaticity Index and feedback on the leaflet, app, call, and planner in the T1 questionnaire and qualitative interviews. …”
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Health system costs of a breast cancer early diagnosis programme in a rural district of Rwanda: a retrospective, cross-sectional economic analysis by Lydia E Pace, Lawrence N Shulman, Jean Claude Mugunga, Parsa Erfani, Kayleigh Pavitra Bhangdia, Rashidah Nambaziira, Lysa Carolle Niteka, Jean Marie Vianney Dusengimana, John Ruhumuriza, Marie Louise Uwineza, Vestine Rugema, Cyprien Shyirambere, Melany Rabideau

“…Total start-up and recurring operational costs were also estimated, as well as health system costs of different scale-up adaptations in other districts.Results One-time start-up costswere US$36 917, recurring operational costswere US$67 711 and clinical costswere US$14 824 over 2 years. …”
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Experiencing the risk of overutilising opioids among patients with chronic non-cancer pain in ambulatory care (ERONA): the protocol of an exploratory, randomised controlled trial by Odette Wegwarth, Joerg J Meerpohl, Norbert Donner-Banzhoff, Claudia Spies, Christine Schmucker, Erika Schulte, Edris Nury, Dirk Brockmann, Stefan Wind, Eva Goebel, Wolf-Dieter Ludwig, Ralph Hertwig

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Combining several indicators to assess the effectiveness of tailor-made health plans in pig farms by Levallois, Pierre, Leblanc-Maridor, Mily, Scollo, Annalisa, Ferrari, Paolo, Belloc, Catherine, Fourichon, Christine

“…Outcome indicators and their monitoring periods should be adapted to each farm and to the targeted health disorder. …”
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OUR EXPERIENCE IN TREATMENT OF ENTEROATMOSPHERIC FISTULAS FORMED AS A RESULT OF MINE-EXPLOSIVE INJURY by Kyrylo Parkhomenko, Anastasia Drozdova, Kostiantyn Prokopenko, Ivan Parkhomenko

“…The second stage is the delimitation of the intestinal fistula with one's tissues or with the help of various "fistula adapters". Next, VAC bandages were installed for active drainage. …”
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