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Daidzein improves muscle atrophy caused by lovastatin by regulating the AMPK/FOXO3a axis
Published 2024-12-01“…Mechanistically, daidzein inhibited lovastatin-induced FOXO3a phosphorylation caused by AMPK activation, thereby inhibiting FOXO3a nuclear translocation to restrain the expression of muscle-related proteins Atrogin-1 and MuRF-1. In C2C12 myotube, administration of AMPK-selective inhibitor Compound C recapitulated the therapeutic effects of daidzein against lovastatin-induced myotubes atrophy, while the anti-atrophy effects of daidzein were lost in the presence of AMPK-selective agonist MK-3903. …”
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642
THE DANUBE DELTA BIOSPHERE RESERVE. GEOGRAPHY, BIODIVERSITY, PROTECTION, MANAGEMENT
Published 2009-12-01“…Hérodote comptait cinq bras au Danube, Strabon, Pline et Ptolemée, accordaient sept bras. …”
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643
Effectiveness of a Web-Based Self-Guided Intervention (MINDxYOU) for Reducing Stress and Promoting Mental Health Among Health Professionals: Results From a Stepped-Wedge Cluster Ra...
Published 2025-02-01“…MethodsIn a stepped-wedge cluster randomized design, 357 health professionals from health centers in Aragon and Málaga, Spain, were recruited. They were divided into 6 clusters—3 per region—and randomly assigned to 1 of the 3 sequences, each starting with a control phase and then transitioning to the intervention phase (the MINDxYOU program) after 8, 16, or 24 weeks. …”
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644
Future Extreme Climate Events Threaten Alpine and Subalpine Woody Plants in China
Published 2025-01-01“…We found fewer than 18% of high‐risk areas of diversity loss were currently protected, with priority conservation areas mainly located in the Daxue, Daliang, Wumeng, and Jade Dragon Snow Mountains, as well as in the Nyingchi. …”
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645
Transdisziplinäre Perspektiven der Queer Studies und der Intersektionalität für die Lehrkräfteprofessionalisierung im Fachbereich „Gender und Deutsch als Fremd- und Zweitsprache“...
Published 2024-12-01“…Sie sollten relevante Methoden und Werkzeuge kennen, um Lernenden (diskursive) Räume für Kritik und Widerstand zu eröffnen und den teilnehmenden Lehrkräften sollte ein Raum gegeben werden, sich als Verbündete wahrzunehmen, die miteinander lernen und arbeiten und gleichzeitig auch eine Verantwortung für diejenigen Lernenden tragen, die nicht in die „heterosexuelle Matrix“ passen.…”
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Comparison of growth models to describe growth from birth to 6 years in a Beninese cohort of children with repeated measurements
Published 2020-09-01“…Objective To select a growth model that best describes individual growth trajectories of children and to present some growth characteristics of this population.Settings Participants were selected from a prospective cohort conducted in three health centres (Allada, Sekou and Attogon) in a semirural region of Benin, sub-Saharan Africa.Participants Children aged 0 to 6 years were recruited in a cohort study with at least two valid height and weight measurements included (n=961).Primary and secondary outcome measures This study compared the goodness-of-fit of three structural growth models (Jenss-Bayley, Reed and a newly adapted version of the Gompertz growth model) on longitudinal weight and height growth data of boys and girls. …”
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648
Efficacy and safety of edoxaban in patients with chronic thromboembolic pulmonary hypertension: protocol for a multicentre, randomised, warfarin-controlled, parallel group trial -...
Published 2022-07-01“…The present trial seeks to evaluate whether edoxaban is non-inferior to warfarin in preventing worsening of CTEPH.Methods and analysis The KABUKI trial (is an investigator-initiated, multicentre, phase 3, randomised, single-blind, parallel-group, warfarin-controlled, non-inferiority trial to evaluate the efficacy and safety of edoxaban versus warfarin (vitamin K Antagonist) in subjects with chronic thromBoembolic pUlmonary hypertension taking warfarin (vitamin K antagonIst) at baseline) is designed to prove the non-inferiority of edoxaban to warfarin in terms of efficacy and safety in patients with CTEPH.Ethics and dissemination This study is approved by the Institutional Review Board of each participating institution. …”
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Evaluación de la doble inoculación Bradyrhizobium-micorrizas y el uso de fitoterápicos de semilla en el crecimiento, eficiencia de inoculación y el rendimiento de un cultivo de soj...
Published 2013-01-01“…Comparados con el control, IBM e IBMC mos- traron un aumento significativo, del orden del 40 %, en los parámetros de crecimiento. …”
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651
Foreword
Published 2025-02-01“…In the realm of translation, KANG Byoung Yoong’s “Unveiling Koreanness in Yoon Ha Lee’s Dragon Pearl: Cultural Representation and Translation Strategies” investigates the representation of Korean identity within the space opera genre, exploring the challenges and strategies involved in translating such cultural elements. …”
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652
Imagen de China en medios latinoamericanos: análisis periodístico de la Franja y la Ruta
Published 2025-01-01“…En octubre de 2023, se celebró en Beijing el III Foro de Cooperación Internacional de la Franja y la Ruta, que atrajo la atención mundial y generó una gran cantidad de noticias relacionadas. …”
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Physical vs. multidimensional frailty in older adults with and without heart failure
Published 2020-06-01Get full text
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656
Slowly digestible starch impairs growth performance of broiler chickens offered low-protein diet supplemental higher amino acid densities by inhibiting the utilization of intestina...
Published 2025-01-01“…The RDS diet suppressed the breast muscle mass by down-regulating expression of mTOR, S6K1, and eIF4E and up-regulating expression of MuRF, CathepsinB, Atrogin-1, and M-calpain compared to the corn starch diet (P < 0.05). …”
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657
El refrany popular «Lloat sia Déu!» en la poesia catalana del segle XVI
Published 2025-01-01“…Procedeix de la capella polifònica del duc de Calàbria Ferran d’Aragó el volum conegut com a Cançoner d’Uppsala, imprès a Venècia en 1556. …”
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658
ASPECTOS PSICOJURÍDICOS DA SÍNDROME ALCOÓLICA FETAL
Published 2019-06-01“…O método adotado foi uma revisão sistemática da literatura de onde se pode depreender que a SAF está se tornando um problema de saúde pública por ser uma das maiores causas de atraso mental. A SAF é uma doença para a qual não existe a cura, porém é totalmente passível de prevenção por meio da abstinência da ingestão de álcool durante o período de gestacional, quando o sistema nervoso está em processo de formação e desenvolvimento. …”
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659
Caracterización acústica de fincas bajo pago por servicios ambientales en la Reserva Forestal Golfo Dulce, Costa Rica
Published 2024-02-01“…La detección automatizada de vocalizaciones indicó que la especie Hylopezus perspicillatus resultó ser más sensible a las diferencias en el paisaje que Trogon bairdii. [Conclusiones]: El uso de índices acústicos, aunque asocia rasgos del grado de conservación del bosque, no resultó un elemento diferenciador de la calidad del ecosistema en las fincas evaluadas, pero el monitoreo de especies mediante la detección de sus vocalizaciones sí resultó promisorio. …”
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AI prediction model for endovascular treatment of vertebrobasilar occlusion with atrial fibrillation
Published 2025-02-01Get full text
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