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1801
Identification and Verification of Novel Biomarkers Involving Rheumatoid Arthritis with Multimachine Learning Algorithms: An In Silicon and In Vivo Study
Published 2024-01-01“…Furthermore, knockdown of CRTAM could significantly suppress the proliferation and invasion ability of RA cell line and thus could be treated as a novel therapeutic target. …”
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1802
Prognostic models of immune-related cell death and stress unveil mechanisms driving macrophage phenotypic evolution in colorectal cancer
Published 2025-01-01“…Furthermore, we performed enrichment analyses and deconvolution algorithms to elucidate the complex interactions between immune cell infiltration and the processes of PCD and stress within a substantial array of transcriptomic data from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus data base (GEO) related to CRC. …”
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1803
The genome sequence of the Montseny horsehair worm, Gordionus montsenyensis sp. nov., a key resource to investigate Ecdysozoa evolution
Published 2024-03-01“…As part of the European Reference Genome Atlas pilot effort to generate reference genomes for European biodiversity, we present the taxonomic description and chromosome-level genome assembly of a newly described species of Nematomorpha (Gordionus montsenyensis Schmidt-Rhaesa & Fernández sp. nov.). …”
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1804
Studies on the Removal of Cadmium Toxic Metal Ions by Natural Clays from Aqueous Solution by Adsorption Process
Published 2021-01-01“…The aim of this study is the valorization of the Moroccan clays (QC-MC and QC-MT) from the Middle Atlas region as adsorbents for the treatment of water contaminated by cadmium Cd (II) ions. …”
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1805
Identification of Five m6A-Related lncRNA Genes as Prognostic Markers for Endometrial Cancer Based on TCGA Database
Published 2022-01-01“…Gene expression and clinical data were extracted from The Cancer Genome Atlas. Coexpression analysis was performed to identify m6A-related lncRNAs, which were entered into univariate Cox regression models for evaluating the prognosis of UCEC. …”
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1806
Identification of HOXA9 methylation as an epigenetic biomarker predicting prognosis and guiding treatment choice in acute myeloid leukemia
Published 2025-02-01“…Methods We systematically first screened the prognostic value of HOXA cluster genes methylation in AML from The Cancer Genome Atlas (TCGA) datasets. Afterwards, the candidate prognosis-related gene HOXA9 were selected for clinical relevance analysis and were further validated in another independent cohort from our research center. …”
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1807
Chromosome-level reference genome assembly for the mountain hare (Lepus timidus)
Published 2025-01-01“…Following the previously published brown hare reference genome assembly, the mountain hare is the second Finnish pilot species for the European Reference Genome Atlas (ERGA) initiative, a collaborative effort to generate reference genomes for European biodiversity. …”
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1808
Eficacia del sistema de retroalimentación en tiempo real en la práctica profesional de estudiantes de educación física
Published 2025-01-01“…Con el objetivo de conocer la percepción de los estudiantes sobre la eficacia del sistema de retroalimentación se aplicó una entrevista semiestructurada con cuatro preguntas, cuyo análisis se llevó con el software Atlas.ti 24. Resultados: Se generaron cuatro grupos de códigos que muestran: a) el valor de la retroalimentación en tiempo real; b) la importancia de la comunicación para mejorar la praxis pedagógica; c) las tensiones generadas por el Sistema de retroalimentación en la práctica; y d) el reconocimiento de aspectos positivos y áreas de mejora para la implementación del sistema de retroalimentación. …”
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1809
Identification and validation of prognostic biomarkers in ccRCC: immune-stromal score and survival prediction
Published 2025-01-01“…Methods Data from the Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) were subjected to analysis to compute immune and stromal scores utilizing the ESTIMATE algorithm. …”
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1810
Genetic and neurochemical profiles underlying cortical morphometric vulnerability to Parkinson’s disease
Published 2025-02-01“…Then we performed gene-category enrichment and spatial correlation analyses to evaluate the specific correspondence between cortical alteration in PD and genetic expression from the Allen Human Brain Atlas and normative neurotransmitter atlases from Neuromaps. …”
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1811
High quality genome assembly of the brown hare (Lepus europaeus) with chromosome-level scaffolding
Published 2024-03-01“…This brown hare genome represents the first Finnish contribution to the European Reference Genome Atlas pilot effort to generate reference genomes for European biodiversity. …”
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1812
Revisiting ABC Transporters and Their Clinical Significance in Glioblastoma
Published 2025-01-01“…Using the datasets in The Cancer Genome Atlas and Gene Expression Omnibus, we found upregulated ABC transporters that either negatively impacted survival in univariate analyses (ABCA1, ABCA13, ABCB9, ABCD4) or were independent negative prognosis factors for patients with GBM (ABCA13, ABCB9). …”
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1813
Downregulated mRNA Expression of ZNF385B Is an Independent Predictor of Breast Cancer
Published 2021-01-01“…Furthermore, data of patients with BC were downloaded from The Cancer Genome Atlas (TCGA). The receiver operating characteristic (ROC) curve of ZNF385B expression was established to explore the diagnostic value of ZNF385B and to obtain the cut-off value of high or low ZNF385B expression in BC. …”
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1814
SUMO modified ETV1 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by facilitating CCL2 transcription in esophageal squamous cell carcinoma ce...
Published 2025-02-01“…Methods Gene expression and immune infiltration in ESCC samples from the Cancer Genome Atlas (TCGA) were analyzed. The expression of ETV1 in clinical samples was detected by real-time PCR, western blot and immunohistochemistry staining. …”
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1815
Therapeutic target genes and regulatory networks of gallic acid in cervical cancer
Published 2025-01-01“…By combining the results of the Gene Expression Omnibus (GEO) and the Cancer Genome Atlas (TCGA) analysis and RNA-seq, the differentially expressed genes (DEGs), including those upregulated and downregulated genes in CC compared with the normal cervix in the GEO and TCGA database, while expressed reversed after treatment with GA, were identified. …”
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1816
Geographical distribution of eight neuromuscular disorders in the Netherlands based on a nationwide registry
Published 2025-01-01“…We provided the first neuromuscular atlas of the Netherlands with maps for eight disorders commonly seen in the neuromuscular practice. …”
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1817
TOM40 as a prognostic oncogene for oral squamous cell carcinoma prognosis
Published 2025-01-01“…Methods TOM40 expression level in OSCC was evaluated using datasets downloaded from The Cancer Genome Atlas (TCGA), as well as clinical data. The correlation between TOM40 expression level and the clinicopathological parameters and survival were analyzed in TCGA. …”
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1818
Identification of SETD4 as an Onco‐Immunological Biomarker Encompassing the Tumor Microenvironment, Prognoses, and Therapeutic Responses in Various Human Cancers
Published 2025-01-01“…Methods Utilizing The Cancer Genome Atlas database, and other publicly accessible platforms, we comprehensively analyzed SETD4 gene expression, methylation patterns, and prognostic significance. …”
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1819
Radiography may not be accurate in assessing acute ankle sprains in children
Published 2025-01-01“…Among these 29 fractures, 20 were chondral avulsion fractures of the distal fibula, and 9 were avulsion fractures of the lateral talus process. …”
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1820
Integrated analysis of cell cycle and p53 signaling pathways related genes in breast, colorectal, lung, and pancreatic cancers: implications for prognosis and drug sensitivity for...
Published 2024-12-01“…Validation of hub genes at mRNA and protein levels was done via GEPIA2 and Human Protein Atlas. Survival analysis was conducted using TCGA data by GEPIA2 and LASSO, and drug sensitivity was analyzed with the GSCA drug bank database, highlighting potential therapeutic targets. …”
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