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    Can the 3rd Hour Value of 100 g Oral Glucose Tolerance Test Be Ignored in the Diagnosis of Gestational Diabetes Mellitus? by Mehmet Metin Altay, Serdinç Özdoğan, Aytaç Tohma, Sertaç Esin, Okyar Erol, Orhan Gelişen, Melih Akkuş, Sinan Karadeniz

    Published 2013-12-01
    “…CONCLUSION: 79% of the patients were diagnosed with first and second hour test results but 21% of the patients were diagnosed with blood glucose levels above the third hour cut-off level. Thus, considering the difficulties of 100 gr. OGTT, third hour values is of diagnostic value and cannot be ignored. …”
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    4,6-Disubstituted pyrimidine-based microtubule affinity-regulating kinase 4 (MARK4) inhibitors: synthesis, characterization, in-vitro activity and in-silico studies by Ashanul Haque, Khalaf M. Alenezi, Mohd. Saeed Maulana Abdul Rasheed, Md. Ataur Rahman, Saleha Anwar, Shahzaib Ahamad, Dinesh Gupta

    Published 2025-01-01
    “…Protein kinases are integral to AD pathology and represent promising targets for therapeutic intervention.MethodsA series of pyrimidine-based compounds 4-(4-(arylsulfonyl)piperazin-1-yl)-6-(thiophen-3-yl)pyrimidine derivatives (8-14) were synthesized and characterised. ATPase inhibition was carried out against the MARK4 enzyme. …”
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