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Attitudes toward Genetic Testing for Hypertension among African American Women and Girls
Published 2013-01-01“…A descriptive correlational research design were used with 183 African American women and girls from Detroit. Correlations between triad membership, age, income, and education level were examined for association with attitudes toward genetic testing. …”
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Neighborhood environment associations with cognitive function and structural brain measures in older African Americans
Published 2025-01-01“…Methods In this study, we examined whether DNA methylation in peripheral blood leukocytes mediates the relationship between neighborhood characteristics and cognitive function (N = 542) or WMH (N = 466) in older African American (AA) participants without preliminary evidence of dementia from the Genetic Epidemiology Network of Arteriopathy (GENOA). …”
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Inflammatory Markers Are Positively Associated with Serum trans-Fatty Acids in an Adult American Population
Published 2017-01-01Get full text
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Intersection of rare pathogenic variants from TCGA in the All of Us Research Program v6
Published 2025-04-01“…Summary: Using rare cancer predisposition alleles derived from The Cancer Genome Atlas (TCGA) and high cancer prevalence (14% of participants) in All of Us (version 6), we assessed the impact of these rare alleles on cancer occurrence in six broad groups of genetic similarity provided by All of Us: African/African American (AFR), Admixed American/Latino (AMR), East Asian (EAS), European (EUR), Middle Eastern (MID), or South Asian (SAS). …”
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Replication of European hypertension associations in a case-control study of 9,534 African Americans.
Published 2021-01-01“…<h4>Objective</h4>Hypertension is more prevalent in African Americans (AA) than other ethnic groups. Genome-wide association studies (GWAS) have identified loci associated with hypertension and other cardio-metabolic traits like type 2 diabetes, coronary artery disease, and body mass index (BMI), however the AA population is underrepresented in these studies. …”
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Epigenetic Markers of Renal Function in African Americans
Published 2013-01-01“…To better understand how these methylation markers play a role in kidney function, we measured 26,428 DNA methylation sites in 972 African Americans from the Genetic Epidemiology Network of Arteriopathy (GENOA) study. …”
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Assisted Stacking of Fungal Disease Resistance Genes in Central American Coffee Cultivars
Published 2025-01-01“…This work aimed to profile the phenotypic and genetic resistance of 160 genotypes belonging to 36 commercial coffee cultivars from five Central American countries regarding resistance to races II and XXXIII of <i>H. vastatrix</i> through phenotypic evaluation and evaluations associated with the genetic loci of resistance to CLR and CBD by molecular markers. …”
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Insight on the Genetics of Atrial Fibrillation in Puerto Rican Hispanics
Published 2021-01-01“…In this study, we compared a genetic dataset of Puerto Rican Hispanics to 111 SNP known to be associated with AF in a large European cohort and determine if they are associated with AF susceptibility in our cohort. …”
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Unraveling the genetic spectrum of inherited deaf-blindness in Portugal
Published 2025-01-01“…Genetic variants were classified according to the American College of Medical Genetics and Genomics; only likely pathogenic or pathogenic variants were considered relevant for solved cases. …”
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The role of candidate genetic polymorphisms in covid-19 susceptibility and outcomes
Published 2025-02-01Get full text
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Genetic Variations in the Human Angiotensin-ConvertingEnzyme 2 and Susceptibility to Coronavirus Disease-19
Published 2023-01-01“…We evaluated the identified variants based on the predictive performance of 5 deleteriousness-scoring methods and the 2015 American College of Medical Genetics and Genomics (ACMG) guidelines. …”
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Genetic Variants in SNCA and the Risk of Sporadic Parkinson’s Disease and Clinical Outcomes: A Review
Published 2017-01-01“…Genetic variations in the SNCA gene are well established by linkage and genome-wide association studies. …”
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North American avian species that migrate in flocks show greater long-term non-breeding range shift rates
Published 2025-01-01“…Therefore, in some cases range-shifts may be limited by the capacity for novel migratory programmes to be transferred between generations, which can be genetically and socially mediated. Methods Here we used 50 years of North American Breeding Bird Survey and Audubon Christmas Bird Count data to test the prediction that breeding and/or non-breeding range-shifts are more prevalent among flocking migrants, which possess a capacity for rapid social transmission of novel migration routes. …”
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Genetic profiling of multidrug-resistant Acinetobacter baumannii from a tertiary care center in Malaysia
Published 2025-02-01Get full text
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