Effect of dietary microalgae on growth performance and health in meat-type quails by Samar M. Mohamed, Mahmoud Alagawany, Mohamed S. El-Kholy, Mohamed M. El-Mekkawy, Ayman S. Salah, Youssef A. Attia, Rashed A. Alhotan, Alessandro Di Cerbo, Antonia Lestingi

“…The DsAp1 group significantly (P=0.003) presented the lowest level of alanine aminotransferase (ALT) and the DsAp2 group significantly (P<0.001) presented the lowest levels of aspartate aminotransferase (AST) and urea. …”
Get full text

Effect of Malaria and Schistosoma mansoni Coinfection on Selected Biochemical Profiles among Patients Attending Selected Health Institutions at Dembiya, Northwest Ethiopia by Wagaw Abebe, Wossenseged Lemma, Yalewayker Tegegne, Amare Mekuanint, Abebe Yenesew, Adane Derso

“…Results. The mean values of alanine aminotransferase and aspartate aminotransferase (37.1 U/L and 41.9 U/L, respectively) in coinfected participants were significantly higher than in the healthy control participants (17.4 U/L and 22.0 U/L, respectively) p<0.05. …”
Get full text

The effect of gut microbiome-targeted therapies in nonalcoholic fatty liver disease: a systematic review and network meta-analysis by Yijia Song, Yijia Song, Yijia Song, Sutong Liu, Lihui Zhang, Lihui Zhang, Wenxia Zhao, Yuanmei Qin, Yuanmei Qin, Minghao Liu

“…Probiotics and synbiotics were associated with a significantly reduction in alanine aminotransferase [ALT, (MD: −5.09; 95%CI: −9.79, −0.39), (MD: −7.38, 95CI%: −11.94, −2.82)] and liver stiffness measurement by elastograph [LSM, (MD: −0.37;95%CI: −0.49, −0.25), (MD: −1.00;95%CI: −1.59, −0.41)]. …”
Get full text

ARAPLARDA PUTPERESTLİK VE HİCAZ PUTLARINDAN/ BEYTLERİNDEN BİRİ OLARAK “ZÜLHALESA” by Hanefi Palabıyık

“…Aslında sürekli yeşil kalmayı başarabilen meyveli veyapraklı bir sarmaşıkla donanmış bir taşın, zaten taşın ve ağacın kutsandığıp.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 8.0px Helvetica}bir toplumda, tanrıça olarak görüldüğünü düşünebiliriz.…”
Get full text

Effects of in ovo feeding of vitamin C on embryonic development, hatching process, and chick rectal temperature of broiler embryos by Shan Du, Jianchuan Zhou, Xiang Ao, Xiang Ao, Yufei Zhu, Yufei Zhu

“…Compared to the NS group, the plasma biochemical indicators in the VC group showed significantly lower levels of alkaline phosphatase (ALP), total protein (TP), albumin (ALB), GLB, total bilirubin (TBIL), TBA, uric acid (UA), high-density lipoprotein cholesterol (HDL-C), and corticosterone (CORT) (p &lt; 0.05). Additionally, alanine aminotransferase (ALT) had an increasing trend (p = 0.059) in the VC group. …”
Get full text

Serum ALT activity and its isoenzymes as potential biomarkers for diagnosis of Sarcopenia in older adults: a retrospective, cross-sectional study by Jiangping Zeng, Nannan Li, Jiaying Ge, Huihui Ma, Siqi Sun, Yujie Jing, Chunhua Qian, Ran Cui, Shen Qu, Hui Sheng

“…Abstract Background Alanine aminotransferase (ALT) is an enzyme crucial for energy and protein metabolism in muscle cells. …”
Get full text

Abnormalities in Blood Parameters in Athletes Taking Anabolic Androgenic Steroidal Agents; an Observational Clinical Study by Mubarak GS, Bamagous GA, Alsanosi SM, Alhindi YZ, Alqashqari HS, Albar HT, Siddiqi AM, Ayoub N, Falemban AH

“…High levels of testosterone, prolactin, alanine transaminase (ALT), aspartate transferase (AST) and lipid profile, and low luteinizing hormone (LH) and follicle-stimulating hormone (FSH) were observed.Conclusion: The unsupervised use of AAS alone or in combination with other hormones and/or supplements may lead to adverse effects. …”
Get full text

Elevated D-dimer on admission may predict poor prognosis in childhood influenza associated encephalopathy by Huizhen Wang, Lingkong Zeng, Xingfeng Cheng, Hui Li, Hong Zhang, Yuanmei Shi, Yong Zhang, Changjian Li

“…In the univariate analysis, the poor prognosis group compared with the clinically cured group showed a significant increase in the number of days of hospitalization (3.0 vs. 9.5 days, P < 0.001), high-sensitivity C-reactive protein (6.80 vs. 1.88 mg/L, P = 0.003), interleukin-6 (20.26 vs. 8.24 pg/mL, P = 0.001), interleukin-10 (11.75 vs. 4.72 pg/mL, P = 0.003), alanine aminotransferase (104.0 vs. 20.0 U/L, P = 0.011), aspartate azelotransferase (186.5 vs. 37.0 U/L, P = 0.003), serum albumin (37.99 vs. 40.76 g/L, P = 0.042), prothrombin time (13.2 vs. 11.4 s, P = 0.017), D-dimer (4.34 vs. 0.44 mg/L FEU, P < 0.001), peripheral blood CD19 B-cell count (35.11 vs. 32.75 cells/µL, P = 0.018), and cerebrospinal fluid chloride (126.82 vs. 125.50 mmol/L, P = 0.027) were statistically different in the above 11 indicators. …”
Get full text

Network Pharmacology Combined With Metabolomics Reveals the Mechanism of Yangxuerongjin Pill Against Type 2 Diabetic Peripheral Neuropathy in Rats by Jin R, Pei H, Yue F, Zhang X, Zhang Z, Xu Y, Li J

“…Metabolomics results showed that the potential metabolic pathways of YXRJP in the treatment of DPN mainly involved amino acid metabolism such as arginine, alanine, aspartic acid, lipid metabolism and nucleotide metabolism.Conclusion: YXRJP can effectively improve the symptoms of DPN rats and reduce nerve damage. …”
Get full text

Anti-LAG-3 antibody LBL-007 plus anti-PD-1 antibody toripalimab in advanced nasopharyngeal carcinoma and other solid tumors: an open-label, multicenter, phase Ib/II trial by Gang Chen, Dong-Chen Sun, Yi Ba, Ya-Xiong Zhang, Ting Zhou, Yuan-Yuan Zhao, Hong-Yun Zhao, Wen-Feng Fang, Yan Huang, Zhen Wang, Chao Deng, De-Sheng Hu, Wei Wang, Jin-Guan Lin, Gui-Ling Li, Su-Xia Luo, Zhi-Chao Fu, Hai-Sheng Zhu, Hui-Li Wang, Sheng-Li Cai, Xiao-Qiang Kang, Li Zhang, Yun-Peng Yang

“…Nine (11.3%) of 80 patients had grade 3 or 4 treatment-related adverse events, the most common of which included anemia (2.5%), hyponatremia (2.5%), increased alanine aminotransferase (2.5%), increased aspartate aminotransferase (1.3%), and fatigue (1.3%). …”
Get full text

Bilim Tarihçisi Prof. Dr. Fuat Sezgin’in Hayatına ve Çalışmalarına Genel Bir Bakış by Abdullah Burgu

“…Bu araştırma, İslâm bilim tarihi ile ilgili mühim çalışmalar yapan ve bu alanın gelişmesine katkı sağlayan F. Sezgin’in kısa yaşam öyküsü ve bilimler tarihi ile ilgili görüşlerinin genel bir değerlendirmesinden oluşmaktadır. …”
Get full text

Novel predictive biomarkers for atonic postpartum hemorrhage as explored by proteomics and metabolomics by Jiangxue Qu, Hai Jiang, Huifeng Shi, Nana Huang, Jiawen Su, Yan Zhang, Lian Chen, Yangyu Zhao

“…The PPH group had significant differences in metabolites and proteins belonging to the β-alanine metabolic pathway. Specifically, the PPH group had downregulation of critical metabolites, including histidine and protein dihydropyrimidine dehydrogenase (DPYD). …”
Get full text

EZH2/miR-142-3p/HMGB1 axis mediates chondrocyte pyroptosis by regulating endoplasmic reticulum stress in knee osteoarthritis by Yang Chen, Shanshan Dong, Xin Zeng, Qing Xu, Mingwei Liang, Guangneng Liao, Lan Li, Bin Shen, Yanrong Lu, Haibo Si, Peifang Wei

“…The expression of the histone methyltransferase enhancer of zeste homolog 2 (EZH2), microRNA-142-3p (miR-142-3p), and high mobility group box 1 (HMGB1) and the levels of ER stress, pyroptosis, and metabolic markers in normal and OA chondrocytes were investigated by western blotting, quantitative polymerase chain reaction, immunohistochemistry, fluorescence in situ hybridization, fluorescein amidite-tyrosine-valine-alanine-aspartic acid-fluoromethyl ketone (FAM-YVAD-FMK)/Hoechst 33342/propidium iodide (PI) staining, lactate dehydrogenase (LDH) release assays, and cell viability assessments. …”
Get full text

Walnut oil prevents hyperlipidemia induced by high-fat diet and regulates intestinal flora and liver metabolism by Rui Yang, Dan Chen, Yanling Chen, Yage Ma, Chaoyin Chen, Shenglan Zhao

“…Levels of TC, TG, LDL-C, activities of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were significantly decreased (p &lt; 0.05), while HDL-C levels were increased (p &lt; 0.05), along with a significant increase in the activity of glutathione peroxidase (GSH-PX) and a decrease in malondialdehyde (MDA) content in serum. …”
Get full text

Application Value of STOP-Bang Questionnaire in Predicting Abnormal Metabolites by Pang Q, Han L, Li J, Xu L, Wang Y

“…In respect of liver function, alanine aminotransferase (ALT) and aspartate transaminase (AST) were both in low/mid-risk group than in high-risk group. …”
Get full text

Nomogram for predicting early cancer-related death due to recurrence after liver resection in hepatocellular carcinoma patients with Barcelona Clinic Liver Cancer (BCLC) stage B/C:... by Zhan-Cheng Qiu, Hao-Zheng Cai, You-Wei Wu, Jun-Long Dai, Wei-Li Qi, Chu-Wen Chen, Yue-Qing Xu, Chuan Li, Tian-Fu Wen

“…Results In our LASSO-logistic regression model, three variables were independently associated with the ECRD due to recurrence: the alpha-fetoprotein-tumor burden score (ATS score, Odd Ratio [OR]: 1.12, p = 0.001), BCLC stage (OR: 4.39, p < 0.001) and the aspartate transaminase (AST) to alanine transaminase (ALT) ratio (AAR, OR: 1.49, p = 0.027) and we established the nomogram model based on these three variables. …”
Get full text

Noninvasive Assessment of Liver Fibrosis by Magnetic Resonance Elastography in Patients with Rheumatic Disease on Long-Term Methotrexate Treatment by Arindam Nandy Roy, Anjani Kumar Darapureddy, Yarram Ashok Kumar

“…However, a positive correlation was observed between MRE and liver biochemical parameters (AST: Alanine transaminase [ALT] ratio, ALT, platelet count, APRI, albumin, and mean liver size; P > 0.05). …”
Get full text

Safety and efficacy of PD-1 inhibitor (sintilimab) combined with transarterial chemoembolization as the initial treatment in patients with intermediate-stage hepatocellular carcino... by Lei Yu, Lan Zhang, Xin Xu, Zheng Wang, Jian Zhou, Jia Fan, Wentao Wang, Zhenggang Ren, Lixing Li, Peiran Huang

“…Treatment-related adverse events (TRAEs) mainly included elevated aspartate aminotransferase levels (19/20, 95.0%), elevated alanine aminotransferase levels (18/20, 90.0%), hypothyroidism (18/20, 90.0%), and reduced appetite (10/20, 50.0%). …”
Get full text

Termination of Repeat Testing in Chemical Laboratories Based on Practice Guidelines: Examining the Effect of Rule-Based Repeat Testing in a Transplantation Center by Neda Soleimani, Amir Azadi, Mohammad Javad Esmaeili, Fatemeh Ghodsi, Reza Ghahramani, Azadeh Hafezi, Tayebeh Hosseyni, Arezoo Arabzadeh, Samira khajeh, Mahsa Farhadi, Sahand Mohammadzadeh

“…., albumin, alkaline phosphatase (ALP), alanine aminotransferase (ALT), amylase, aspartate aminotransferase (AST), bilirubin total (BT), bilirubin direct (BD), blood urea nitrogen (BUN), calcium, chloride (Cl), cholesterol total (CholT), creatine kinase (CK), creatinine (Cr), glucose, gamma-glutamyl transferase (GGT), high-density lipoprotein-cholesterol (HDL-c), iron, lactate dehydrogenase (LDH), LDL-c, lipase, magnesium (Mg), phosphorus (Ph), protein total (ProtT), total iron binding capacity (TIBC), triglyceride (TG), and uric acid) were assessed in both critical and noncritical ranges over two consecutive months (routine subjective test repeats in the first month and rule-based repeats in the second month). …”
Get full text

Ethyl Acetate Extract of <i>Cichorium glandulosum</i> Activates the P21/Nrf2/HO-1 Pathway to Alleviate Oxidative Stress in a Mouse Model of Alcoholic Liver Disease by Shuwen Qi, Chunzi Zhang, Junlin Yan, Xiaoyan Ma, Yewei Zhong, Wenhui Hou, Juan Zhang, Tuxia Pang, Xiaoli Ma

“…Results: UPLC-Q-Orbitrap-MS identified 81 CGE compounds, mainly including terpenoids, flavonoids, and phenylpropanoids. …”
Get full text