Determination of the effect of danofloxacin on 8-hydroxy-2-deoxyguanosine level by Devran Coşkun, Rahmi Canbar, Yasemin Korkmaz, Burak Dik, Ayşe Er, Enver Yazar

“…In addition, to determine on heart [Troponin I, creatine kinase-MB (CK-MB) isoenzyme, lactate dehydrogenase (LDH), aspartate aminotransferase (AST)], liver [Alkaline phosphatase (ALP), alanine aminotransferase (ALT)] and kidney [Blood urea nitrogen (BUN), creatinine] damage biomarkers and hemogram parameters [White blood cell count (WBC), red blood cell count (RBC), platelet count, hemoglobin, hematocrit].…”
Get full text

Hepatic function markers as prognostic factors in patients with acute kidney injury undergoing continuous renal replacement therapy by Takuya Nishino, Yoshiaki Kubota, Tetsuya Kashiwagi, Akio Hirama, Kuniya Asai, Masahiro Yasutake, Shinichiro Kumita

“…In Phase 1, the T-Bil, aspartate transaminase (AST), alanine transaminase (ALT), and AST/ALT (De Ritis ratio) levels at CRRT initiation were not associated with the prognosis, while T-Bil, AST, and the De Ritis ratio 3 days after CRRT initiation were independent factors. …”
Get full text

EFFICACY OF THIONONTRITE-S FOR PREVENTION OF METABOLIC LIVER DISEASE IN CATTLE by Ye. V. Tyapkina, M. P. Semenenko, Ye. V.  Kuzminova, A. A.  Abramov

“…At the end of the experiment the level of alanine aminotransferase in the first group was 1.8 times less than the control levels, the level of aspartate aminotransferase was 1.6 times lower than the negative control levels. …”
Get full text

Evaluation of Antidiabetic Properties of the Leaves Extract of Ficus vallis-choudae Delile in a Model of Type 2 Diabetes Induced by High-Fat Diet and Streptozotocin by Kilenma Kolefer, David Miaffo, Roger Ponka

“…There was a decrease in alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activity and in urea and serum creatinine levels following the administration of AEFV. …”
Get full text

Liver Biomarkers and Lipid Profiles in Mexican and Mexican-American 10- to 14-Year-Old Adolescents at Risk for Type 2 Diabetes by Ana Cecilia Fernández-Gaxiola, Roxana Valdés-Ramos, Kimberly Fulda, Ana Laura Guadarrama López, Beatriz E. Martínez-Carrillo, Susan F. Franks, Shane Fernando

“…Liver enzymes alanine aminotransferase (ALT) and gamma glutamyl transferase (GGT) are markers for type 2 diabetes mellitus (T2DM); alkaline phosphatase is a marker of liver disease. …”
Get full text

Hepatoprotective Effects of Crude Stem Bark Extracts and Solvent Fractions of Cordia africana against Acetaminophen-Induced Liver Injury in Rats by Gudeta Duga Geresu, Shemsu Umer, Mahlet Arayaselassie, Genet Ashebir, Eyasu Makonnen

“…Oral administration of APAP resulted in a significant increase in serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), TB, low-density lipoprotein (LDL), total cholesterol (TC), and triglycerides (TGs) and decrease in serum high-density lipoprotein (HDL). …”
Get full text

Insulin Resistance Associated with Plasma Xanthine Oxidoreductase Activity Independent of Visceral Adiposity and Adiponectin Level: MedCity21 Health Examination Registry by Masafumi Kurajoh, Shinya Fukumoto, Takayo Murase, Takashi Nakamura, Takuma Ishihara, Hirofumi Go, Kouji Yamamoto, Shinya Nakatani, Akihiro Tsuda, Tomoaki Morioka, Katsuhito Mori, Yasuo Imanishi, Masaaki Inaba, Masanori Emoto

“…Multiple regression analysis showed that HOMA-IR was significantly (p=0.020) associated with plasma XOR activity independent of other factors, including VFA and adiponectin level, as well as age, sex, alcohol drinking habit, smoking habit, alanine transaminase, HbA1c, and eGFR. The “sex∗HOMA−IR” interaction was not significant (p=0.89), indicating that sex difference does not have an effect on the relationship between HOMA-IR and plasma XOR activity. …”
Get full text

Antik Çağda Lykaonia-Isauria Sınır Bölgesi by Mehmet Kurt, Esra Bulut

“…Bütün bu arkeolojik ve epigrafik veriler, Lykaonia-Isauria sınırını oluşturan bu alanın siyasal ve askeri açıdan öneminin yanı sıra, tarım ve hayvancılık bakımından da önemli bir potansiyele sahip olduğunu açıkça kanıtlamaktadır.Bu çalışmada Antik kaynakların aktardıkları bilgiler ve bölgede tespit edilen yazıtlar ile arkeolojik veriler ışığında Lykaonia-Isauria bölgelerinin sınırını oluşturan coğrafyanın antik çağdaki siyasal, askeri, sosyo-ekonomik ve kültürel durumu ele alınmıştır.…”
Get full text

Physiological Alterations due to Hepatotoxicity and the Protective Role of Cleome viscosa Linn Seed Extract in Experimental Animals by Addai-Mensah Donkor, Martin Ntiamoah Donkor, Benjamin Ahenkorah, Kwadwo Asante Asare-Konadu, Emmanuel Asiedu, Richard Mosobil

“…Serum biomarkers (aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), and total protein (TP)) were evaluated to find out the effect. …”
Get full text

Glutamine deprivation confers immunotherapy resistance by inhibiting IFN-γ signaling in cancer cells by Zhiwei Yuan, Taiyan Yu, Xu Wang, Kelin Meng, Tianlai Wang, Boyu Wang, Yu Xi, Congjian Wang, Chenxi Zeng, Shaojie Hu, Yitao Tian, Hui Xiong, Qi Wang, Wenbin Zou, Xue Wang, Yi Gao, Xiangning Fu, Lequn Li

“…Treatment with V9302, an inhibitor of the alanine-serine-cysteine transporter (ASCT2), enhanced the IFN-γ-driven response of cancer cells and increased the efficacy of PD-1 blockade therapy. …”
Get full text

Evaluation of Hepatoprotective Potential of Polyherbal Preparations in CCl4-Induced Hepatotoxicity in Mice by Rayhana Begum, Sonia Akther Papia, Mst Marium Begum, Hongbin Wang, Rubaba Karim, Rebeka Sultana, Priyanka Rani Das, Taslima Begum, Md. Ragibul Islam, Nargis Manwar, Md. Sohanur Rahman

“…Twenty-four hours after CCl4 administration, the mice were monitored for the effects of PLFs on liver morphology, biochemical parameters including serum aspartate transaminase (AST), serum alanine transaminase (ALT), alkaline phosphatase (ALP), and total bilirubin. …”
Get full text

Serum Muscle Enzymes as Indicator for Gingival Wound Healing in Rabbits Orally Receiving Pomegranate Peel Extract by Bakhtiar Muhialdin Ahmed

“…The aim of this study is to evaluate serum muscle enzymes; Creatine phospho kinase (CPK), aspartate aminotransferase (AST), Alanine aminotransferase (ALT) and Lactate dehydrogenase (LDH) activities in gingival wound healing process in rabbits orally administrated pomegranate peel extract (PPE). …”
Get full text

Küreselleşmenin Yoksulluk Üzerine Etkisi: Türkiye Örneği by Başak Karşıyakalı, Gökhan Ersoy

“…Küreselleşme sürecinin etki alanın genişlemesi 1980 sonrası uygulanan neo-liberal politikalar ile birlikte olmuştur. …”
Get full text

Therapeutic effects of Pueraria lobata (Willd.) Ohwi root and Hovenia dulcis Thunb. extracts on alcoholic liver disease: Network pharmacology and experimental validation by Zhendong Chen, Yu Yue, Hongyan An, Haisu Yan, Hyeok-Joo Park, Pei Lin

“…Moreover. inflammatory responses were mitigated, as indicated by reductions in the expression of tumor necrosis factor-alpha and interleukin-6, and we detected reduction in the levels of alanine aminotransferase and aspartate aminotransferase, thereby indicating hepatoprotective effects. …”
Get full text

The Use of Perovskia abrotanoides Extract in Ameliorating Heat Stress-Induced Oxidative Damage and Improving Growth Efficiency in Carp Juveniles (Cyprinus carpio) by Hossein Adineh, Saeed Zahedi, Morteza Yousefi, Zeynab Sedaghat, Sevdan Yilmaz, Ebrahim Gholamalipour Alamdari, Mohammad Farhangi

“…Serum cortisol, glucose, triglyceride, cholesterol, and malondialdehyde levels as well as catalase, alanine aminotransferase, and aspartate aminotransferase activities were significantly decreased generally in all PAE-supplemented groups compared to the control groups before and/or after high-temperature stress (32°C). …”
Get full text

Iron Overload in Transfusion-Dependent Indonesian Thalassemic Patients by Pandji Irani Fianza, Anita Rahmawati, Sri Hudaya Widihastha, Shofura Afifah, Mohammad Ghozali, Andre Indrajaya, Dilli Marayuzan Akbar Pratama, Dimmy Prasetya, Teddy Arnold Sihite, Mas Rizky A. A. Syamsunarno, Djatnika Setiabudi, Suthat Fucharoen, Ramdan Panigoro

“…In terms of age of first blood transfusion, subjects with ferritin >5000 ng/mL were the youngest among others. The alanine aminotransferase (ALT) levels in group with serum ferritin >5000 ng/mL were significantly higher than those of the group with serum ferritin <2500 ng/mL. …”
Get full text

Comparison Of ALT In Type 2 Diabetics with And Without Fatty Liver Disease by Kausar Malik, Faiza Batool, Lubna Meraj, Shazia Saddiq, Abrar Akbar, Hina Hanif Mughal

“… Objective: To determine the association of alanine aminotransferase in type 2 diabetic patients with and without fatty liver disease. …”
Get full text

Evaluating the Hepatoprotective Potential of Ginger Ethanolic Extract Against Lambda-Cyhalothrin-Induced Toxicity in Male Rats by Mustafa Q Mustafa, Zainab JM Jawad

“…Upon completion of the study, blood ‎samples were collected for liver ‎enzymes alanine aminotransferase (ALT), aspartate aminotransferase (AST)‎, ‎and alkaline phosphatase (ALP) ‎assessment. …”
Get full text

Integrated analysis of biochemical, transcriptomic, and metabolomic response mechanisms in Ussuri catfish (Pseudobagrus ussuriensis) under acute heat stress by Qing Liu, Yang Cao, Ruyi Hu, Libo Gu, Lirong Yang, Yu Liu, Weiwei Wang, Liang Xiao, Bugao Li

“…Biochemical results indicated that acute heat stress significantly impacted the activities of superoxide dismutase, catalase, and alanine aminotransferase, as well as the levels of glutathione, malondialdehyde, and total antioxidant capacity, with alterations remaining even after temperature recovery. …”
Get full text

Clinical and biochemical characteristics for patients with polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes syndrome: a pilot observational study by Pei Li, Ye Zhang, Li-Min Luo, Wen-Qing Wang, Jing Li, Yan Cheng, Xiao Dang, Yang Chen, Wei Jiang

“…Most patients suffered with hyperpigmentation (n = 18), organomegaly (n = 18), elevated vascular endothelial growth factor (VEGF) (n = 17), extravascular volume overload (n = 15), sclerotic bone lesions (n = 11), and hypothyroidism (n = 10). Serum alanine aminotransferase, aspartate aminotransferase, total bilirubin, total protein, and albumin levels were down-regulated, while uric acid level was up-regulated in patients with POEMS syndrome. …”
Get full text