Cover, Content, and Editorial Note from Borneo J Pharm Vol. 7 No. 4 November 2024 by Chief Editor of Borneo J Pharm

“…Alhamdulillahirabbil ‘alamin. The next edition of the Borneo Journal of Pharmacy (Borneo J Pharm), has been published in November 2024. …”
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Antioxidative and hepatoprotective activities of a novel polysaccharide (LSAP) from Lepista sordida mycelia by Yingyin Xu, Yuanhui Li, Yuxiao Lu, Xiaobin Feng, Guoting Tian, Qinghong Liu

“…Administration of LSAP in mice prior to CCl4 significantly prevented the CCl4-induced elevation in serum alanine aminotransferase, aspartate aminotransferase, and hepatic malondialdehyde. …”
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Biochemical characterization of solid state fermented maize cob (Zea mays) using Rhizopus oligosporusand its application in poultry feed production by Amaka Ndego, Theresa Ezedom, Egoamaka Egbune, Nyerhovwo Tonukari

“…Fermentation did not induce a significant difference (p<0.05) in the activities of serum aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP).Conclusion The observed increase in proteins and sugars in the fermented products suggests their suitability as excellent components for animal feed production. …”
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Synthesis of Amino Acid Analogues of 5H-Dibenz[b,f]azepine and Evaluation of their Radical Scavenging Activity by H. Vijay Kumar, C. R. Gnanendra, Nagaraja Naik

“…A method for the synthesis of tyrosine, phenyl alanine, hydroxy proline and threonine free amino acid analogues of 5H-dibenz[b,f]azepine is proposed. 5H-dibenz[b,f]azepine was prepared by known method. …”
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Radyo Televizyon Yayıncılığında Küreselleşme ve Ulusal Yayıncılık Üzerindeki Etkileri by Ayhan Ünlüler

“…Bu teknolojilerin yatırımcısı durumundaki uluslararası şirketler kitle iletişimini hem ticari etkinliklerinin tanıtım aracı yapmışlar hem de kitle iletişim araçlarının kendilerini ürünleriyle birlikte ticari metalara dönüştürmüşlerdir. Uzunca süre kamusal alanın temsil aracı olarak algılanan kitle iletişim araçlarının ticaret alanına kayarak bir yandan siyasi otoritenin kontrolünden çıkmasından, bir yandan da kamu yararına hizmetten uzaklaşmasından endişe duyan kitle iletişiminin daha çok tüketicisi konumundaki ülkelerin siyasi güçleri ve sivil toplum örgütleri, günümüzde en azından ticarileşmenin olası zararlarını önleyecek önlemler peşinde koşmaktadırlar. …”
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Can Nonfibrotic Nonalcoholic Steatohepatitis Be Effectively Identified by Supersonic Shear Imaging? by Jiajia Yang, Liwu Lin, Ensheng Xue, Dengke Hong, Yan Yang, Meifang Xu, Zhikui Chen

“…Multivariate analysis showed that only fibrosis and inflammation were the independent factors affecting liver elasticity of NAFLD (P≤0.001), while inflammation, steatosis, and ballooning degeneration were all independently related to liver elasticity in rabbits without fibrosis (P<0.01). In addition, alanine aminotransferase was the only biochemical factor independently related to liver elasticity (P≤0.001). …”
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A Higher Serum Anion Gap Is Associated with the Risk of Progressing to Impaired Fasting Glucose and Diabetes by Yingchao Zhang, Fengran Xiong, Ruxuan Zhao, Tingting Shi, Jing Lu, Jinkui Yang

“…After adjusting for age, sex, body mass index (BMI), high-density lipoprotein (HDL), low-density lipoprotein (LDL), alanine aminotransferase (ALT), aspartate aminotransferase (AST), systolic blood pressure (SBP), diastolic blood pressure (DBP), potassium, and albumin at baseline, the participants in the upper tertiles of serum anion gap (SAG) had higher odds of progressing to IFG or diabetes than those in the lower tertiles. …”
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3-Hydroxybutyrate alleviates septic liver injury by promoting macrophage polarization from M1 to M2 by Hu Jingjuan, Deng Fan, Sun Qishun, Min Yue, Feng Siyuan, Wu Ling, Chen Xiaofeng, Liu Kexuan

“…The survival rate, liver histopathological damage, serum levels of Alanine Transaminase(ALT) and Aspartate Aminotransferase(AST), and hepatic mRNA expression of inflammatory cytokines IL-1β and IL-6 were evaluated. …”
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Clinical Course of Untreated and Treated Chronic Hepatitis B in Pregnant Patients: A Prospective Study by Yasemin Nadir, Ayse Batirel, Ayse Yasemin Karsidag, Fatma Kaya Narter, Ahmet Nadir

“…The treated group had significantly higher pre- and postpartum alanine aminotransferase levels more than the untreated group, although there were no significant differences in other biochemical parameters. …”
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Quercetin Zinc and Iron Metal Complexes Protect against Sodium Arsenite Intoxication in the Hepato-Renal System of Wistar Rats via the Oxidative Stress Pathway by Oluwatoyin O. Ojo, Deborah I. Fatokun, Ikechukwu P. Ejidike, Rachel U. Awolope, Saheed O. Sanni

“…Plasmatic aspartate transferase (AST), alanine transferase (ALT), creatinine (CREA), and total protein (TP) were estimated. …”
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Metabolic dysfunction-associated liver disease and biliary lithiasis in children with Down Syndrome: a retrospective study by Renato Nisihara, Nayane Hiba Fuga, Liete Maia, Marcelo Gasparin Mansur, Fernanda Liberatti, Maiana Rossasi, Nanci Oliveira

“…No age or sex differences were seen in low- and high-density lipoprotein cholesterol. Alanine transferase (ALT) and aspartate transferase (AST) levels were within normal ranges and showed no differences concerning sex or age. …”
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H. Wendl Leaf Metabolites Potentiate the Radiosensitivity of Hepatocellular Carcinoma Through Ki67 and PARP Inhibition by Nabil M. Selim PhD, Seham S. El-Hawary PhD, Soheir M. El Zalabani PhD, Rehab Nabil Shamma PhD, Nariman El Sayed Mahdy PhD, Noheir H. Sherif PhD, Khayrya A. Youssif PhD, Usama Ramadan Abdelmohsen PhD, Mai H. Mekkawy PhD, Hanan A. Fahmy PhD

“…Besides, the NE administration and/or γ-irradiation (IRR) significantly reduced the elevated alanine aminotransferase (ALT), total proteins, and albumin levels in HCC-induced rats. …”
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Investigation of the Protective Effect of Probiotic Lactobacillus plantarum Ep-M17 on the Hepatopancreas of Penaeus vannamei by Xiaoman Hu, Wenlong Xu, Hao Li, Bowen Lu, Yang Du, Jiong Chen

“…Moreover, the incorporation of Ep-M17 into shrimp diets increased the levels of β-alanine, and histidine in the hepatopancreas, enhancing anti-inflammatory capacity and improving the shrimp’s immune response. …”
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Radioprotective effects of polysaccharides from Poria cocos peels against 60Co-γ induced oxidative damage in vitro and in vivo by Keke Suo, Chaoqiang Zheng, Zhipeng Li, Limin Hao, Jiaqing Zhu, Changcheng Zhao, Yanling Shi, Juanjuan Yi, Jike Lu

“…In the present study, the main components and monosaccharide compositions of the polysaccharides from Poria cocos peels (PCPP) and its radioprotective activities against 60Co-γ induced oxidative damage in vitro and in vivo were evaluated. …”
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Development and internal validation of a metabolism-related model for predicting 30-day mortality in neonatal sepsis by Xiangwen Tu, Junkun Chen, Wen Liu

“…Multivariate logistic regression analysis revealed that alanine(ALA), citrulline(CIT)), octadecanoylcarnitine(C18) and methionine(MET) were identified as independent risk factors for 30-day mortality of neonatal sepsis. …”
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Therapy with Interleukin-22 Alleviates Hepatic Injury and Hemostasis Dysregulation in Rat Model of Acute Liver Failure by Tariq Helal Ashour

“…The following parameters were investigated: (1) survival rate, (2) serum levels of liver function enzymes (aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP)), total bilirubin (TBILI), and total albumen (ALB), (3) blood clotting tests (prothrombin time (PT), activated partial thromboplastin time (aPTT), and fibrinogen level (FIB)) and white blood cells (WBCs), red blood cells (RBCs), and platelet counts, (4) hepatic levels of tumor necrosis factor-α (TNF-α) and cyclooxygenase-2 (COX-2), and (5) liver histopathology. …”
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Changes in the hematology and blood metabolites of guinea pigs (Cavia porcellus) under intensive rearing system in humid tropical conditions by Daniel Paredes-López, Rizal Robles-Huaynate, Uriel Aldava-Pardave, Miguel Morales-Cauti

“…In serum, profiles of glucose, total protein (TP), albumin, total cholesterol (TC), triglycerides, total bilirubin (TB), and direct bilirubin (DB), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were determined. …”
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Dr. Besim Ömer Paşa’nın Nevsâl-i Âfiyet’inde Mekteb-i Tıbbiye-i Şahane by Ahmet Zeki İzgöer

“…Dr.Besim Ömer [Akalın] Paşa tarafından İstanbul’da 1315-1322 tarihlerinde müstakildört cilt halinde toplam 2.400 sayfa olarak yayınlanan Nevsâl-i Âfiyet isimlisağlık yıllıklarında 1903’te açılan Mekteb-i Tıbbiye-i Şahane ile ilgilibirinci elden kaynak bilgiler verilmektedir. …”
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Moringa oleifera Lam. leaf extract mitigates carbon tetrachloride-mediated hepatic inflammation and apoptosis via targeting oxidative stress and toll-like receptor 4/nuclear factor... by Samah M. Fathy, Mohammed S.M. Mohammed

“…MOLE markedly decreased the elevation of serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in consistence with the ameliorating effect on CCl4-induced histopathological abnormalities. …”
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Effect of single dose dexamethasone (0.1 mg/kg) on white blood cell counts and serum glucose levels in healthy ewes by Orhan Corum, Burak Dik, Ayse Er

“…White blood cell, red blood cell, platelet, hematocrit and hemoglobin levels were measured by hemocell counter, whereas serum glucose, lactate dehydrogenase, alkaline phosphatase, total bilirubin, alanine aminotransferase, aspartate aminotransferase, gamma glutamyltransferase, total protein, albumin, blood urea nitrogen, creatinine, cholesterol, triglyceride, high density lipoprotein and low density lipoprotein levels were determined by auto-analyzer.…”
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