Cement Dust Exposure and Perturbations in Some Elements and Lung and Liver Functions of Cement Factory Workers by Egbe Edmund Richard, Nsonwu-Anyanwu Augusta Chinyere, Offor Sunday Jeremaiah, Usoro Chinyere Adanna Opara, Etukudo Maise Henrieta, Egbe Deborah Ifunanya

“…PEFR, liver function {aspartate and alanine transaminases (AST and ALT) and total and conjugated bilirubin (TB and CB)}, and serum elements {lead (Pb), copper (Cu), manganese (Mn), iron (Fe), cadmium (Cd), selenium (Se), chromium (Cr), zinc (Zn), and arsenic (As)} were determined using peak flow meter, colorimetry, and atomic absorption spectrometry, respectively. …”
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Improving the binding affinity of plastic degrading cutinase with polyethylene terephthalate (PET) and polyurethane (PU); an in-silico study by Deves Sabari V L, Gokulnath Rajmohan, Roshine S B, Srivaishnavi S, Kishore Nagasubramanian, Senthil Kumar G, Ponnusami Venkatachalam

“…In this work, unconserved regions of cutinase were identified as potential mutation sites to enhance binding efficiency. In-silico Alanine Scanning Mutagenesis (ASM) and Site Saturation Mutagenesis (SSM) were performed as screening tests to find variants of cutinase with better docking scores for both ligands, specifically S136D, N28M, and S136Q. …”
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Exploring EPR Parameters of 187Re Complexes for Designing New MRI Probes: From the Gas Phase to Solution and a Model Protein Environment by Gustavo A. Andolpho, Elaine F. F. da Cunha, Teodorico C. Ramalho

“…The docking studies point out that ReABT interacts with amino acids residues of alanine, aspartate, and lysine from the PI3K active site. …”
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Study of Zuojin Pill in Treating Chronic Atrophic Gastritis by UPLC-Q-TOF/MS Based on Serum and Urine Metabolomics Combined with Network Pharmacology by Shihua Wu, Xing Chen, Honghong Liu, Ruilin Wang, Jianyu Li, Jianxia Wen, Tao Yang, Ying Wei, Sichen Ren, Shizhang Wei, Manyi Jing, Haotian Li, Min Wang, Houlin Xia, Yanling Zhao

“…Metabolomic results indicated that the therapeutic effects of ZJP were mainly related to ten metabolites, namely, choline, L-threonine, hydroxypyruvic acid, creatine, taurine, succinic acid, cis-aconitic acid, citric acid, succinic acid semialdehyde, and uric acid. …”
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A retrospective clinical study on the influencing factors of Clostridium difficile infection in elderly patients by Yang Chen, Yingjun Gong, Cui Li, Huan Li, Jia Chen, Hui Su, Xiaoming Wang, Xiaoxuan Ning

“…[Results] The use rate of proton pump inhibitors, antibiotics and glucocorticoids in the positive group was higher than that in the negative group (P<0.05), the hemoglobin, alanine aminotransferase, aspartate aminotransferase, albumin, alkaline phosphatase and γ-glutamyl transferase and vitamin D levels in the positive group were lower than those in the negative group (P < 0.05), and the serum creatinine level in the positive group was higher than that in the negative group(P<0.05).Multivariate binary logistic regression analysis showed that hemoglobin, albumin, and vitamin D were protective factors for Clostridium difficile infection (P < 0.05), and antibiotic use and serum creatinine were independent risk factors for Clostridium difficile infection(P<0.05). …”
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A prediction model of liver fat fraction and presence of non-alcoholic fatty liver disease (NAFLD) among patients with overweight or obesity by Jie Chen, Jiang Yue, Jingjing Fu, Shengyun He, Qianjing Liu, Minglan Yang, Wang Zhang, Hua Xu, Qing Lu, Jing Ma

“…The Shang Hai Steatosis Index (SHSI) incorporates alanine aminotransferase (ALT), aspartate aminotransferase (AST), fasting insulin, and 1-h postload glycaemic levels, thereby furnishing the capability to predict NAFLD with an area under the receiver operator characteristic (AUROC) of 0.87. …”
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Pendekatan Integratif Pendidikan Tauhid dan Nilai-nilai Moderasi Beragama dalam Pembentukan Akhlak Terpuji by Danang Dwi Basuki

“…This paradigm reflects Islam as rahmatan lil 'alamin, as a solution to the challenges of character education in the era of diversity. …”
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A utilização do xadrez como recurso metodológico para o ensino da geografia política na Educação básica: uma experiência do projeto “Residência Pedagógica” em Caicó/RN/Brasil... by Iapony Rodrigues Galvão, Fábio Márcio de Azevedo

“…In this way, the present research, accomplished in the degree in Geography of the “Centro de Ensino Superior do Seridó”, linked to the Federal University of Rio Grande do Norte, from the pedagogical interventions of the program "Residência Pedagógica" at the State School Professor Antônio Aladim de Araújo, in Caicó / RN, demonstrated that the coherent use of this element of play helped not only in the teaching of Geography but also in other disciplines in the curriculum, since it increased the possibilities of concentration of the students in the classes taught in the other disciplines, generating advances in performance and learning.…”
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Manometric Measurement of the Sphincter of Oddi in Patients with Common Bile Duct Stones: A Consecutive Study of the Han Population of China by Yadong Feng, Jie Zhang, Chunhua Jiao, Hong Zhu, Wenfang Cheng, Shunfu Xu, Bin Xiao, Jinliang Ni, Xiaoxing Chen

“…There was no significant difference in the basal SO pressure, amplitude, and frequency when compared with the CBD diameter, CBD stone number, prior cholecystectomy, periampullary diverticula, and symptoms. Levels of alanine aminotransferase, aspartate transaminase, γ-glutamyl transpeptidase, and alkaline phosphatase showed no significant difference in patients with normal or elevated basal SO pressure. …”
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Effect of the Antibiotic Neomycin on the Toxicity of the Glycoside Vicine in Rats by Mahmoud S. Arbid, Khaled M. M. Koriem, Gihan F. Asaad, Hoda A. Megahed

“…Serum protein and globulin were significantly decreased but serum albumin showed insignificant decrease in vicine and neomycin groups compared to control. Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were significantly decreased in the vicine group. …”
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Comparative Biochemical and Histopathological Studies on the Efficacy of Metformin and Virgin Olive Oil against Streptozotocin-Induced Diabetes in Sprague-Dawley Rats by Khadijah Saeed Balamash, Huda Mohammed Alkreathy, Elham Hamed Al Gahdali, Sawsan Omer Khoja, Aftab Ahmad

“…The results showed a significant increase in alanine aminotransferase (ALT) and alkaline phosphatase (ALP) levels in diabetic rats. …”
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Elevated Aminotransferase Activity as an Indication of Muscular Dystrophy: Case Reports and Review of the Literature by S Zamora, C Adams, JD Butzner, H Machida, Rb Scott

“…Five male children are reported in whom incidental recognition of elevated serum alanine aminotransferase (ALT) activity initiated investigation to identify the cause of suspected hepatocellular injury. …”
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GABA promotes peroxisome proliferation in Triticum monococcum leaves by Yunus Şahin, Taras Nazarov, Ercan Selçuk Ünlü, Andrei Smertenko, Nusret Zencrici

“…The most commonly upregulated gene in differentiated leaves across all datasets of both species was BETAINE ALANINE DEHYDROGENASE (BADH). BADH functions in catabolism of polyamines where it converts 4‐aminobutyraldehyde (ABAL) to 4‐aminobutyrate (GABA). …”
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Predictors of HBsAg seroclearance in HBeAg-negative chronic hepatitis B patients treated with nucleotide analogs plus polyethylene glycol interferon by Yan Peng, Mingzhe Ma, Ting Liu, Wenmin He, Shutao Lin, Wa Zhong, Xiaohui Min

“…Through using univariate and multivariate analysis, we confirmed the predictive value of HBsAg, alanine aminotransferase (ALT) at week 24, and ALT change values from baseline to week 24. …”
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Two Cysteines in Raf Kinase Inhibitor Protein Make Differential Contributions to Structural Dynamics In Vitro by Hyun Sang Cho, Mohammad Faysal Al Mazid, Eun-Young Lee, Md Abu Rayhan, Hyoun Sook Kim, Byung Il Lee, Hye Jin You

“…Here, we identified the role of cysteine 133 in RKIP structural dynamics using recombinant human RKIP (rhRKIP) proteins purified from <i>Escherichia coli</i> BL21(DE3) cells. Mutation of alanine or serine instead of cysteine in RKIP proteins did not affect the biochemical characteristics, while dynamic light scattering and liquid chromatography (LC) quadrupole time-of-flight (Q-TOF) mass spectrometry (MS) suggested distinct peaks in solution, which were identified via LC–MS/MS analyses, and further clarified the role of cysteine in RKIP dimerization. rhRKIP dimer formation was abrogated by a 32-aa peptide mimicking the region between two RKIP proteins for dimerization. …”
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Evaluation of some laboratory data in traumatic dogs by Semih Altan, Fahrettin Alkan, Yılmaz Koç

“…The obtained blood samples were analyzed for hematology, blood gas, serum biochemistry [alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatine kinase (CK), Phosphorus (P), cholesterol (Chol), creatinine (Crea), gamma glutamyl transferase (GGT), lactate dehydrogenase (LDH), total protein (TP), triglyceride (Trig), blood urea nitrogen (BUN)] and thiobarbutyric acid reactive substance (TBARs) values.…”
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Importance of fasting serum glucose, haemoglobin a1c and fructosamine in the diagnosis of diabetes by Bahadır Ersan, Mahmut Ok

“…Fasting serum glucose, fructosamine, insulin, haemoglobin HbA1c, total cholesterol, triglyceride, urea, aspartate amino transferase and alanin amino transferase levels were measured.<p> <b>Results:</b> Statistically significantly increases of serum fasting glucose, fructosamine, haemoglobin A1c, total cholesterol and triglyceride concentrations and decreases of serum insulin levels and red blood cell, paced cell volume and haemoglobin values were determined (p<0.05) in both groups.…”
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The role of adipose and muscle tissue breakdown on interorgan energy substrate fluxes in a Pseudomonas aeruginosa induced sepsis model in female pigs by Ryan Morse, Gabriella A. M. Ten Have, John J. Thaden, Marielle P. K. J. Engelen, Sarah Rice, Martin Hagve, Nicolaas E. P. Deutz

“…The hindquarter showed a higher release of alanine (p = 0.0002), glutamine (p = 0.003), and lactate (p = 0.0007), but not for glycerol (p = 0.5718). …”
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Methotrexate-Associated Nonalcoholic Fatty Liver Disease with Transaminitis in Rheumatoid Arthritis by Rajalingham Sakthiswary, Grace Yin Lai Chan, Ee Tzun Koh, Khai Pang Leong, Bernard Yu Hor Thong

“…Among the cases, the cumulative dose of MTX was found to have a significant positive correlation with the alanine transaminase (ALT) level (P<0.05, standardised beta coefficient 0.512). …”
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Effects and Potential Mechanisms of Pioglitazone on Lipid Metabolism in Obese Diabetic KKAy Mice by Jun Peng, Yi Huan, Qian Jiang, Su-juan Sun, Chun-ming Jia, Zhu-fang Shen

“…Pioglitazone treatment resulted in deteriorated microvesicular steatosis and elevated hepatic triglyceride levels, though plasma triglyceride and free fatty acid levels were reduced by the treatment, compared to nontreated KKAy mice. Plasma alanine aminotransferase activities were also significantly increased. …”
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