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2301
Saikosaponin D improves nonalcoholic fatty liver disease via gut microbiota-bile acid metabolism pathway
Published 2024-09-01“…Non-alcoholic fatty liver disease (NAFLD) is the main cause of chronic liver disease worldwide. Bupleurum is widely used in the treatment of non-alcoholic fatty liver, and saikosaponin D (SSD) is one of the main active components of Bupleurum. …”
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2302
Intraperitoneal fipronil effects on liver histopathological, biochemistry and morphology in Caspian kutum, Rutilus frisii kutum (Kamenskii, 1901)
Published 2017-12-01“…This dependence was also observed for HSI and the liver biochemical test (alanine and aspartate transaminase). Liver histological alterations showed that fipronil can be a potential factor in liver carcinoma.…”
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2303
Accurate Prediction of Advanced Liver Fibrosis Using the Decision Tree Learning Algorithm in Chronic Hepatitis C Egyptian Patients
Published 2016-01-01“…Model 1 uses six parameters, while model 2 uses four, which are similar to FIB-4 features except alpha-fetoprotein instead of alanine aminotransferase. Sensitivity and receiver operating characteristic curve were performed to evaluate the performance of the proposed models. …”
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2304
Celal Bayar Arşivi Belgelerinde İbo Osman (Bekir Ağa)’ın Millî Mücadele Hatıraları
Published 2023-06-01“…Bu çalışmada Celal Bayar’ın kişisel arşivi kullanılarak, Millî Mücadele’nin güney cephesinde Fransızlarla olan mücadelede İbo Osman lakaplı Bekir Ağa’nın bölgedeki gözlemlerine yer verilecektir. Bu gözlemler verilirken güney cephesinde gerçekleşen olaylarla karşılaştırılarak aktarılacaktır. …”
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2305
SPİNOZA FELSEFESİNDE ZİHİN: DOĞASI VE KAYNAĞI
Published 2015-12-01“…Tözün kendisini açığa vurduğu,zorunluluğun ve Tanrısal nedenselliğin egemen olduğu bir alanın da,insan zihni olduğu söylenebilir. Bedeni ve zihni ile bir bütünlük oluşturaninsan, diğer varlıklar gibi doğanın değişmez ve sonsuz yasalarına tabidir.Bu makalede, zihnin doğası ve kaynağına, zorunluluğun ve Tanrısalnedenselliğin insan zihnindeki etkisine değinilecektir. …”
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2306
Kant Düşüncesinde Metafiziğin Geçerli Bir Yönteme Kavuşturulması
Published 2024-06-01“…O, bu ideaların geçerli olduğu alanın pratik alan olduğunu göstermekle metafiziği bir yönteme kavuşturduğunu ve böylece aklın önüne geçilemez yönelimin sonucunda içine düştüğü yanılsamalardan kurtulduğunu düşünür. …”
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2307
GEMİDE VE BORNOVA BORNOVA FİLMLERİ BAĞLAMINDA YENİ TÜRK SİNEMASI'NDA ANTİKAHRAMANIN YÜKSELİŞİ
Published 2013-11-01“…Bu çalışma kapsamında da yeni sinemanın antikahramanı odağına taşıyan filmlerde, antikahramanların hangi toplumsal yapıdan beslenerek ortaya çıktığı ve yeni sinemaya hakim olan bu eril kahramanların nasıl bir kültürel temsilin parçası oldukları konusu, seçilen örnek filmler aracılığıyla tartışılacaktır. Çalışma; Serdar Akar'ın Gemide ve İnan Temelkuran'ın Bornova Bornova filmleri bağlamında günümüz Türk Sineması'nda yerleşik kahraman algısının değişmesi, tüm kusurları ve zayıflıkları ile kurulan kahramanyaratımının fazlalaşma nedenleri, bununla birlikte de iyice yoğunlaşan eril anlatıların Yeni Türk Sineması'nı nasıl şekillendirdiği açıklanacaktır. …”
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2308
Birinci Dünya Savaşı’nda Amerikan Kütüphane Derneği’nin ABD Ordusuna Yönelik Hazırladığı Propaganda Posterleri Üzerine İnceleme
Published 2021-06-01“…Bu seferberlik kapsamında hem ABD halkının kitap bağışı yapmalarının hem de ABD askerlerinin kitap okuma alışkanlığı kazanmalarının sağlanması için propaganda posterleri etkin bir şekilde kullanılmıştır. Çalışmada ALA’nın kitlelerin kitap bağışı yapmalarında ve askerlerin kitap okumalarının teşvik edilmesinde propaganda posterlerini ne şekilde kullandığının ortaya konulması amaçlanmıştır. …”
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2309
Impact of polyvinyl chloride nano-plastics on the biochemical status of Oreochromis niloticus under a predicted global warming scenario
Published 2025-01-01“…After 4 days, the biochemical response of fish exposed to PVC-NPs and elevated temperatures showed a significant increase in the levels of plasma total proteins, albumin, globulin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), creatinine, and uric acid. …”
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2310
Effects of Cytochrome P450 Inhibitors on Itraconazole and Fluconazole Induced Cytotoxicity in Hepatocytes
Published 2009-01-01“…In vitro incubation of hepatocytes with itraconazole revealed significantly lower viability when compared to fluconazole as assessed by lactate dehydrogenase, aspartate aminotransferase and alanine aminotransferase activities. The cytotoxicity of itraconazole was enhanced when incubated with hepatocytes pretreated with SKF 525A. …”
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2311
Metabolomics identifies plasma biomarkers of localized radiation injury
Published 2025-01-01“…The identified biomarker signature consists in a 6-metabolite panel including putrescine, uracil, 2,3-dihydroxybenzoate, 3-hydroxybenzoate, L-alanine and pyroglutamate, that can discriminate mice according to radiation dose and injury severity. …”
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2312
The Relationship between Inflammatory Marker Levels and Hepatitis C Virus Severity
Published 2016-01-01“…The aspartate aminotransferase (AST)/alanine aminotransferase (ALT) ratio (AAR), AST-to-platelet ratio index (APRI), and fibrosis index based on the four factors (FIB-4) scores in HCV-related cirrhosis patients were significantly higher than in chronic HCV patients (all P<0.001). …”
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2313
Thiacloprid exposure disrupts the gut-liver axis and induces liver dysfunction in the Reeves' turtles (Mauremys reevesii)
Published 2025-01-01“…Furthermore, elevated levels of liver function indicators, including aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), total bile acid (TBA), and triglyceride (TG), were positively correlated with increased THI concentrations. …”
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2314
Spirulina maxima as a valuable ingredient: Determination of broad fatty acid and amino acid profiles and nutritional quality and anti-amylase capacity
Published 2025-06-01“…The amino acid profile shows high levels of alanine (17.38 g), glycine (11.75 g), and glutamic acid (9.69 g) per 100 g protein. …”
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2315
Exploring transition states of protein conformational changes via out-of-distribution detection in the hyperspherical latent space
Published 2025-01-01“…We demonstrate the power of TS-DAR by applying it to a 2D potential, alanine dipeptide, and the translocation of a DNA motor protein on DNA, where it outperforms previous methods in identifying transition states.…”
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2316
Mesenchymal Stem Cell Transplantation for Liver Cell Failure: A New Direction and Option
Published 2018-01-01“…Nine articles (n=476) related with LF patients were enrolled. After MSCT, alanine aminotransferase (ALT) baseline decreased largely at half a month (P<0.05); total bilirubin (TBIL) baseline declined to a certain stable level of 78.57 μmol/L at 2 and 3 months (P<0.05). …”
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2317
Application of Principal Component Analysis as a Prediction Model for Feline Sporotrichosis
Published 2025-01-01“…Principal component analysis (PCA) with two principal components, followed by binary logistic regression, and binary logistic regression analysis, with independent variables and backward elimination modeling, were performed to evaluate hematological (n = 56) and biochemical (n = 34) analytes, including red blood cells, hemoglobin, hematocrit, leukocytes, segmented neutrophils, band neutrophils, eosinophils, lymphocytes, monocytes, total plasma protein, albumin, urea, creatinine, and alanine aminotransferase. Two logistic regression models (PCA and independent variables) were employed to search for a predicted model to correlate fixed (isolated) and disseminated cutaneous lesion patterns. …”
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2318
Biochemical properties and substrate specificity of GOB-38 in Elizabethkingia anophelis
Published 2025-01-01“…It is important to highlight that GOB-38 exhibits a distinct active site composition compared to GOB-1/18, featuring hydrophilic amino acids Thr51 and Glu141 at both ends of its active center instead of hydrophobic alanine, potentially indicating a preference for imipenem. …”
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2319
Exploring the molecular mechanisms of tirzepatide in alleviating metabolic dysfunction-associated fatty liver in mice through integration of metabolomics, lipidomics, and proteomic...
Published 2025-01-01“…The results demonstrated that tirzepatide significantly reduced serum levels of alanine transaminase (ALT) and aspartate transaminase (AST), as well as hepatic triglycerides (TG) and total cholesterol (TC), indicating its efficacy in treating MAFLD. …”
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2320
Circulating IL-1β, IL-17, and IP-10 as Potential Predictors of Hepatitis B Virus Infection Prognosis
Published 2022-01-01“…Furthermore, positive correlations of IP-10 with alanine aminotransferase and aspartate aminotransferase levels were observed (rs=0.546 and 0.644, respectively; P<0.001). …”
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