Verbascoside exerts an anti-atherosclerotic effect by regulating liver glycerophospholipid metabolism by Peng Lei, Jialin Lü, Tie Yao, Peng Zhang, Xin Chai, Yuefei Wang, Miaomiao Jiang

“…After 12 weeks of administration during the feeding period, the levels of total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C) in the plasma of mice were significantly decreased, the formation of arterial plaques was delayed, and the levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and lactate dehydrogenase (LDH) in plasma were alleviated, showing the hepatoprotective effect. …”
Get full text

A Case of Glycogenic Hepatopathy as a Complication of Poorly Controlled Type 1 Diabetes Mellitus by Samhitha Munugoti, Vamsee Reddy, Gaurav Patel, Maneesh Gaddam, Triveni Abburi

“…An acute elevation of liver enzymes was noted as the DKA resolved, with the alanine transferase and aspartate transferase levels elevated to more than 50 times the normal limit within the next 24 hours. …”
Get full text

Shorter Leukocyte Telomere Length in Relation to Presumed Nonalcoholic Fatty Liver Disease in Mexican-American Men in NHANES 1999–2002 by Janet M. Wojcicki, David Rehkopf, Elissa Epel, Philip Rosenthal

“…Data from the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2002 was used to explore the relationship between leukocyte telomere length and presumed NAFLD, as indicated by elevated serum alanine aminotransferase (ALT) levels, obesity, or abdominal obesity. …”
Get full text

Results of non-interventional observational study of ursodeoxycholic acid in primary biliary cirrhosis by Yelena N. Shirokova, Anna F. Sheptulina

“…Treatment with «Livodexa®» in a dose of 15 mg/kg/day resulted in a statistically significant decrease of biochemical marker levels: alanine transaminase, aspartate aminotransferase, alkaline phosphatase, gamma-glutamyltranspeptidase, total and conjugated bilirubin at the 30th day of treatment (visit 2; p…”
Get full text

N-acetylglutamate synthetase deficiency - literature review by Krystian Wdowiak, Agnieszka Maciocha, Julia Wąż, Aleksandra Witas, Justyna Drogoń, Weronika Chachaj, Natalia Szymkowiak, Ewa Gardocka

“…Key biochemical markers include elevated ammonia, glutamine, and alanine; decreased citrulline; and respiratory alkalosis. …”
Get full text

Simple and Efficient Rout for Synthesis of Spinel Nanopigments by Leila Torkian, Maryam Daghighi, Zahra Boorboor

“…Nano-sized CoxMg1−xAl2O4 (x = 0, 0.1, 0.2, 0.4, 0.6, 0.8, and 1) inorganic pigments were synthesized via combustion method using β-alanine, as a single and novel fuel, at 800°C in open furnace. …”
Get full text

Parasitaemia and Its Relation to Hematological Parameters and Liver Function among Patients Malaria in Abs, Hajjah, Northwest Yemen by Mohamed Al-Salahy, Bushra Shnawa, Gamal Abed, Ahmed Mandour, Ali Al-Ezzi

“…Hematological parameters and serum levels of aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), and bilirubin (total and direct) as test indicators of liver function were studied. …”
Get full text

A Single Consumption of High Amounts of the Brazil Nuts Improves Lipid Profile of Healthy Volunteers by Elisângela Colpo, Carlos Dalton de Avila Vilanova, Luiz Gustavo Brenner Reetz, Marta Maria Medeiros Frescura Duarte, Iria Luiza Gomes Farias, Edson Irineu Muller, Aline Lima Hermes Muller, Erico Marlon Moraes Flores, Roger Wagner, João Batista Teixeira da Rocha

“….), triglycerides, selenium, aspartate and alanine aminotransferases, albumin, total protein, alkaline phosphatase, gamma GT, urea, creatinine, and C-reactive protein. …”
Get full text

Cross-trait multivariate GWAS confirms health implications of pubertal timing by Siquan Zhou, Yujie Xu, Jingyuan Xiong, Guo Cheng

“…Linkage disequilibrium score regression and Mendelian randomisation analysis establish causal associations between earlier puberty and both accelerated ageing and the risk of developing cardiovascular disease and osteoporosis. We find that alanine aminotransferase, glycated haemoglobin, high-density lipoprotein cholesterol and Parabacteroides levels are mediators of these relationships, and establish that controlling oily fish and retinol intake may be beneficial for promoting healthy pubertal development.…”
Get full text

Review of the Urinary Schistosomiasis Control in Morocco (1960–2018) by A. Balahbib, F. Amarir, S. Bouhout, M. Rhajaoui, E. Adlaoui, A. Sadak

“…A majority of cases were reported in Agadir province (25%), Errachidia (18%), and Beni Mellal (13%). …”
Get full text

Reducing oxidative stress and hepatoprotective effect of water extracts from Pu-erh tea on rats with high-fat diet by Jingjing Su, Xueqing Wang, Wenjun Song, Xiaoli Bai, Changwen Li

“…The malondialdehyde (MDA) and glucose (Glu) levels and the activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST), nitric oxide synthase (NOS), and pyruvate kinase (PK) in serum were determined. …”
Get full text

Effects of Pioglitazone on Asymmetric Dimethylarginine and Components of the Metabolic Syndrome in Nondiabetic Patients (EPICAMP Study): A Double-Blind, Randomized Clinical Trial by Pedram Shokouh, Adel Joharimoghadam, Hamidreza Roohafza, Masoumeh Sadeghi, Allahyar Golabchi, Maryam Boshtam, Nizal Sarrafzadegan

“…Compared with the placebo group, alanine and aspartate transaminases were decreased and high-density lipoprotein cholesterol was increased after treatment with pioglitazone. …”
Get full text

Remifentanil Preconditioning Attenuates Hepatic Ischemia-Reperfusion Injury in Rats via Neuronal Activation in Dorsal Vagal Complex by Cui Cui, Fang Yu, Suqing Yin, Yuting Yang, Yingfu Jiao, Chiwai Cheung, Xiaomin Wang, Bo Qi, Yaling Liu, Peiying Li, Weifeng Yu, Jie Xiao, Liqun Yang

“…The results revealed that intravenous pretreatment with remifentanil decreased serum aminotransferases and hepatic histologic damage; however, an intraperitoneal injection of μ-opioid receptor antagonist did not abolish the protection of remifentanil preconditioning. c-Fos immunofluorescence of the brain stem showed that dorsal motor nucleus of the vagus was activated after remifentanil preconditioning. Moreover, serum alanine aminotransferase, histopathologic damage, and apoptosis decreased in remifentanil preconditioning group compared to vagotomized animals with remifentanil preconditioning, and there was no statistical difference of TNF-α and IL-6 between NS/Va and RPC/Va groups. …”
Get full text

Synthesis of New Schiff Base from Natural Products for Remediation of Water Pollution with Heavy Metals in Industrial Areas by Reham Hassan, Hassan Arida, Manal Montasser, Nehad Abdel Latif

“…The results showed that there is no significant difference between the effects of Schiff base on serum (alanine amino transferase) ALT and creatinine concentration activities in treated mice and control, at confidence limits 95%.…”
Get full text

A BIOCHEMICAL STUDY TO EVALUATE THE EFFICIENCY OF SOME LOCAL CULTURE MEDIA IN THE GROWTH OF THE REISHI MUSHROOM by A. Th. Mahmoud, I. A. Abed, O. H. M. Almohammedi

“…The study concluded that levels of organic compounds in biomass varied significantly depending on the type of medium and the cultivated strain. Alanine had the highest concentration among all amino acids while arginine was the lowest, and phenols and flavonoids had higher concentrations in the Iraqi strain grown on sugarcane bagasse compared to the Chinese strain for all mediums. …”
Get full text

Plasma α-Glutathione S-Transferase Evaluation in Patients with Acute and Chronic Liver Injury by Jolanta Czuczejko, Celestyna Mila-Kierzenkowska, Karolina Szewczyk-Golec

“…The concentration of α-GST and the activities of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were measured in all examined groups. α-GST, ALT, and AST were statistically higher in all patient groups than in the control group. …”
Get full text

Ten Machine Learning Models for Predicting Preoperative and Postoperative Coagulopathy in Patients With Trauma: Multicenter Cohort Study by Xiaojuan Xiong, Hong Fu, Bo Xu, Wang Wei, Mi Zhou, Peng Hu, Yunqin Ren, Qingxiang Mao

“…ConclusionsKey PPTIC risk factors include (1) prolonged activated partial thromboplastin time, prothrombin time, and international normalized ratio; (2) low levels of hemoglobin, hematocrit, red blood cells, calcium, and sodium; (3) low diastolic blood pressure; (4) elevated alanine aminotransferase and aspartate aminotransferase levels; (5) admission heart rate; and (6) the need for emergency surgery and transfusion. …”
Get full text

IFN-γ licenses normal and pathogenic ALPK1/TIFA pathway in human monocytes by Amandine Martin, Solène Caron, Mélissa Marcotte, Pauline Bronnec, Etienne Garneret, Nora Martel, Georgina Maalouf, Pascal Sève, David Saadoun, Yvan Jamilloux, Thomas Henry

Get full text

Development and validation of a food-related quality of life questionnaire (CANUT-QVA) for cancer patients by Kenza Drareni, Catherine Mercier, Reisya Rizki Riantiningtyas, Anestis Dougkas, Benjamin Riche, Pascale Roux, Chantal Fingal, Hélène Labrosse, Fadila Farsi, David Dayde, Mélanie Roche, Julie Anne Nazare, Arnaud Fournel, Delphine Maucort-Boulch, Moustafa Bensafi, Véronique Mourier, Amandine Bruyas, Agnès Giboreau

Get full text

Multisite Kinetic Modeling of 13C Metabolic MR Using [1-13C]Pyruvate by Pedro A. Gómez Damián, Jonathan I. Sperl, Martin A. Janich, Oleksandr Khegai, Florian Wiesinger, Steffen J. Glaser, Axel Haase, Markus Schwaiger, Rolf F. Schulte, Marion I. Menzel

“…Quantification of metabolite conversion between [1-13C]pyruvate and downstream metabolites [1-13C]alanine, [1-13C]lactate, and [13C]bicarbonate can be achieved through kinetic modeling. …”
Get full text