Correlation Analysis of the Entorhinal Cortex-Hippocampus Nerve Fiber Changes and Memory Dysfunction in P301L-Tau Mouse Model and Molecular Mechanism by CHEN Xiaocheng, LIANG Shengxiang, LIN Bingbing, LIU Weilin, HUANG Jia

“…ObjectiveTo observe the correlation between the changes of entorhinal cortex-hippocampus nerve fibers and learning and memory function in the P301L-Tau mouse model of Alzheimer's disease (AD) and related molecular mechanism, so as to provide the evidence for Tau-targeted treatment in AD patients.MethodsA total of 16 3-month-old male C57BL/6 mice were randomly divided into non-vector virus control group (control group) and P301L-Tau model group (model group), with eight mice in each group. …”
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Machine learning derivation of two cardiac arrest subphenotypes with distinct responses to treatment by Weidong Zhang, Chenxi Wu, Peifeng Ni, Sheng Zhang, Hongwei Zhang, Ying Zhu, Wei Hu, Mengyuan Diao

“…Results After applying exclusion criteria, 719 CA patients were included in the study, with a median age of 67.22 years (IQR: 55.50-79.34), of whom 63.28% were male. The analysis delineated two distinct subphenotypes: Subphenotype 1 (SP1) and Subphenotype 2 (SP2). …”
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Prevalence and determinants of metabolic syndrome among type2 diabetic patients using different diagnosis criteria in ethiopia: systematic review and meta-analysis by Chilot Kassa Mekonnen, Hailemichael Kindie Abate, Abere Woretaw Azagew, Alebachew Ferede Zegeye

“…The odds of having metabolic syndrome was reduced for females (Adjusted Odds Ratio [AOR] = 0.55, 95% CI: 0.35–0.87) compared to males. However, the odds of metabolic syndrome increased with alcohol intake (AOR = 1.44, 95% CI: 1.03–2.01), the odds of living in urban areas(AOR = 2.12, 95% CI: 1.55–2.88), and the odds of having a diabetes duration of six or more years since diagnosis (AOR = 2.94, 95% CI: 1.17–7.41) were significant predictors. …”
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Changes in muscle performance among older adults with myeloid malignancies engaging in a mobile health (mHealth) exercise intervention: a single arm pilot study by Marielle Jensen-Battaglia, Po-Ju Lin, Chandrika Sanapala, Erin E. Watson, Jason H. Mendler, Jane Liesveld, Ying Wang, Elisabeth Hayward, Marissa LoCastro, Soroush Mortaz, Richard F. Dunne, Karen Mustian, Kah Poh Loh

“…Results A total of 25 patients completed baseline assessments, 23 with muscle performance data at baseline, 16 at post-intervention. Of these, most were male (n = 10, 62.5%) and had acute myeloid leukemia (n = 9, 56.3%). …”
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Lymphadenopathies: A Retrospective Study of Epidemiology, Characteristics, Diagnosis and Treatment Outcomes of Patients in a Tertiary Hospital in Mogadishu-Somalia by Kıratlı K, Bulut M, Ali MA, Aysin M, Ali AM, Mohamed Hirsi I, Bashir AM

“…The purpose of this research was to identify the clinical and diagnostic characteristics of Somalian patients suffering from swollen lymph nodes.Methods: Under the purview of this study, the diagnoses, patient clinical courses, and treatment outcomes were ascertained retrospectively by analyzing the biochemical, microbiological, radiological, and pathological data of the cases in all age groups who underwent therapy for lymphadenitis at Mogadishu Somali Turkey Recep Tayyip Erdoğan Training and Research Hospital between January 2016 and September 2023.Results: During the study period, 317 patients were followed up, with 53.3% of the patients as female, 46.7% as male, 28.1% as pediatric, 63.1% as adult, and 8.8% were elderly patients. …”
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Recalcitrant Female Pattern Hair Loss Like Alopecia Unveils Unexpected Rare Entity by Nouh AH, Elgendy FM, Gobran FA, Zhuravlova MS

“…This hair loss can resemble common male-pattern baldness. While MUHH mainly affects hair, it may also be linked to other conditions such as skin tumors (trichoepithelioma), limb abnormalities, eye issues, wide-spaced teeth, and syndromes like Ehlers-Danlos or atopy.Because MUHH is so rare, diagnosing it can be difficult, and many healthcare providers may not immediately recognize it. …”
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Comprehensive symptom assessment using Integrated Palliative care Outcome Scale in hospitalized heart failure patients by Yasuhiro Hamatani, Moritake Iguchi, Yurika Ikeyama, Atsuko Kunugida, Megumi Ogawa, Natsushige Yasuda, Kana Fujimoto, Hidenori Ichihara, Misaki Sakai, Tae Kinoshita, Yasuyo Nakashima, Masaharu Akao

“…Of 294 patients (mean age: 77.5 ± 12.0 years, male: 168 patients, New York Heart Association class IV: 96 patients, mean left ventricular ejection fraction [LVEF]: 44%, and median N‐terminal pro B‐type natriuretic peptide [NT‐proBNP] level: 4418 ng/L), the median (IQR) total IPOS score on admission was 19 (12, 27) and they were widely distributed (minimum: 0 – maximum: 52). …”
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Study of pattern of lipid profile amongst type II diabetic patients of two major tribal populations of Tripura by Sagar Samrat Debbarma, Arunabha Dasgupta, Atanu Ghosh, Kanak Choudhury, Prithvijit Kole, Sonali Paul, Brainist Kalai, V. Saikumar

“…A total of 48 subjects were male and 42 were female. The mean age of the study population was 56.99 ± 9.97 years. …”
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The Financial Implications of Pancreatic Surgery: The Hospital Is the Big Winner, Not the Surgeon! by Nitzan Zohar, MD, Avinoam Nevler, MD, Sean P. Maher, Matthew C. Rosenthal, Florence Williams, Wilbur B. Bowne, MD, FACS, Charles J. Yeo, MD, FACS, Harish Lavu, MD, FACS

“…Longer operative time was correlated with increased hospital and anesthesia charges, without a significant increase in surgeon charges (P < 0.001, P < 0.001, and P = 0.2, respectively). Male sex, diabetes, and low serum albumin correlated with greater total hospital charges (P = 0.01, P = 0.01, and P = 0.03, respectively). …”
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Soil-transmitted helminthiasis among adolescents in Anaocha Local Government Area, Anambra State, Nigeria: Insights and recommendations for effective control. by Ogechukwu B Aribodor, Eunice C Jacob, Nwadiuto O Azugo, Uche C Ngenegbo, Ifeanyi Obika, Emmanuel M Obikwelu, Obiageli J Nebe

“…Analysis was performed using SPSS version 25, incorporating descriptive statistics and multinomial logistic regression, with statistical significance set at p<0.05. Of the 443 (213 males (48.0%) and 230 females (52.0%) adolescents studied, the overall prevalence of STH observed was 35.2% (156/443). …”
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Long-Term Treatment Outcomes of Micropulse Transscleral Cyclophotocoagulation in Primary and Secondary Glaucoma: A 5-Year Analysis by Ronald M. P. C. de Crom, Stefani Kujovic-Aleksov, Carroll A. B. Webers, Tos T. J. M. Berendschot, Henny J. M. Beckers

“…Mean age was 67.3 ± 13.9 years; 58.2% were male. Glaucoma subtypes were primary glaucoma (n = 108) and secondary glaucoma (n = 57). …”
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Dynamic Digital Radiography (DDR) in the Diagnosis of a Diaphragm Dysfunction by Elisa Calabrò, Tiana Lisnic, Maurizio Cè, Laura Macrì, Francesca Lucrezia Rabaiotti, Michaela Cellina

“…Dynamic digital radiography (DDR) is a recent imaging technique that allows for real-time visualization of thoracic and pulmonary movement in synchronization with the breathing cycle, providing useful clinical information. A 46-year-old male, a former smoker, was evaluated for unexplained dyspnea and reduced exercise tolerance. …”
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Olutasidenib in combination with azacitidine induces durable complete remissions in patients with relapsed or refractory mIDH1 acute myeloid leukemia: a multicohort open-label phas... by Jorge E. Cortes, Gail J. Roboz, Maria R. Baer, Brian A. Jonas, Gary J. Schiller, Karen Yee, P. Brent Ferrell, Jay Yang, Eunice S. Wang, William G. Blum, Alice Mims, Hua Tian, Aaron Sheppard, Stéphane de Botton, Pau Montesinos, Antonio Curti, Justin M. Watts, the Olutasidenib Combination Therapy Study Group

“…Median age was 66 years (range 28–82) and 54% were male. Most patients (83%) had 2 + prior regimens, including a hypomethylating agent in 40%, IDH1 inhibitor therapy in 31% (olutasidenib in 24%), and hematopoietic stem cell transplant in 10%. …”
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The Effects of Artificial vs. Natural Rearing on Growth Performance, Thyroid Hormone Levels, Locomotor Activity, Carcass Traits and Meat Quality Characteristics in Chios Lambs by Panagiotis Simitzis, Georgia Alexopoulou, Eftychis Karampekos, Konstantina Linardopoulou, Anargyros Rigakis, Niki Stamelou, Michael Goliomytis, Iosif Bizelis, Ioannis Bossis

“…Therefore, the present study aimed to examine the influence of artificial rearing on growth performance, thyroid hormone levels, locomotor activity, carcass traits and meat quality characteristics in lambs of the Chios breed, which is one of the most well-known Greek dairy sheep breeds. Twenty-one singleton male lambs were assigned into two feeding regimes; natural rearing NR (<i>n</i> = 11) and AR (<i>n</i> = 10). …”
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Effect of L-Citrulline on Creatine Kinase MM (CK-MM) Isoenzymes in Mice: An In Vivo Study Focusing on Immunohistochemistry Analysis by Dhoni Akbar Ghozali, Annisa Aghnia Rahma, Shafira Nur Hanifa, Muhana Fawwazy Ilyas

“…This study utilized immunohistochemistry analysis to investigate the effect of L-citrulline supplementation on CK-MM expression post-eccentric exercise in male BALB/c mice. This in vivo study was conducted with a post-test-only design. …”
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Association between demographic, clinical characteristics and severe complications by SARS-CoV-2 infection in a community-based healthcare network in Chile. by Javiera Leniz, Sam Hernández-Jaña, Mauricio Soto, Eduardo Arenas, Paula Margozzini, Francisco Suarez, Daniel Capurro, María Paulina Rojas, Claudia Bambs

“…Among the 44,674 people,148(0.33%) died due to COVID-19 infection. Older age and male sex were consistently associated with a higher risk of the three COVID-19 complications. …”
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Optimizing Clinical Postgraduate Training: Perspectives of Postgraduate Alumni Regarding Their Residency Training at Mbarara University of Science and Technology, Uganda by Tibaijuka L, Atimango L, Kajjimu J, Owaraganise A, Kamukama N, Kato PK, Mugyenyi GR, Kayondo M, Boatin AA, Ngonzi J

“…Descriptive summary statistics and thematic analysis were used to analyze the data.Results: Ninety-five MUST alumni (34.3% response rate) participated, predominantly males (80%), aged 31– 40 (69%), and Ugandans (72%). …”
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Tobacco Use, Risk Perceptions, and Characteristics of Adults Who Used a Heated Tobacco Product (IQOS) in the United States: Cross-Sectional Survey Study by Hui G Cheng, Brendan Noggle, Andrea R Vansickel, Edward G Largo, Pierpaolo Magnani

“…Of the 688 participants, 424 (61.6%) were male, 502 (73.0%) were non–Hispanic White, and the mean age was 45 years. …”
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Integrated Microbiome and Metabolome Analysis Reveals Correlations Between Gut Microbiota Components and Metabolic Profiles in Mice With Mitoxantrone-Induced Cardiotoxicity by Zhang Q, Liang D, Zhang C, Ye L, Sun P, Zhu H, Zhao Y, Li Y, Guan Y, Zhang H

“…We aim to explore the possible correlations between gut microbiota (GM) compositions and cardiometabolic (CM) disorder in MTX-triggered cardiotoxicity mice.Methods: MTX cumulative dose of 6 mg/kg was administered to healthy Kunming male mice to trigger cardiotoxicity, with 1 mg/kg twice weekly for a duration of 3 weeks. …”
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Significance of supervision sampling in control of communicable respiratory disease simulated by a new model during different stages of the disease by Alphonse Houssou Hounye, Xiaogao Pan, Yuqi Zhao, Cong Cao, Jiaoju Wang, Abidi Mimi Venunye, Li Xiong, Xiangping Chai, Muzhou Hou

“…Furthermore, The incidence hazard of Males and Females was 1.39(1.23–1.58), and 1.43(1.26–1.63), respectively. …”
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