Effectiveness of late and very late antivenom administration on recovery from snakebite-induced coagulopathy in French Guiana: a population-based studyResearch in context by Jean Marc Pujo, Stephanie Houcke, Guy Roger Lontsi Ngoulla, Vivian Laurent, Boubacar Signaté, Rémi Mutricy, Alexis Frémery, Flaubert Nkontcho, Ibtissem Ben Amara, José María Gutiérrez, Dabor Resiere, Hatem Kallel

“…The median age of patients was 42 years (IQR: 29–53), 65.4% were male and 34.6% were female (104 and 55 out of 159 patients) without difference regarding the demographic parameters between groups. …”
Get full text

The Effects of MyChoices and LYNX Mobile Apps on HIV Testing and Pre-Exposure Prophylaxis Use by Young US Sexual Minority Men: Results From a National Randomized Controlled Trial by Katie B Biello, Kenneth H Mayer, Hyman Scott, Pablo K Valente, Jonathan Hill-Rorie, Susan Buchbinder, Lucinda Ackah-Toffey, Patrick S Sullivan, Lisa Hightow-Weidman, Albert Y Liu

“…MethodsBetween October 2019 and May 2022, we implemented a 3-arm, parallel randomized controlled trial in 9 US cities to test the efficacy of the LYNX and MyChoices apps against standard of care (SOC) among young sexual minority men (aged 15-29 years) reporting anal sex with cisgender male or transgender female in the last 12 months. …”
Get full text

Protective mechanism of safflower yellow injection on myocardial ischemia-reperfusion injury in rats by activating NLRP3 inflammasome by Lingmei Li, Ce Cao, Hao Guo, Li Lin, Lei Li, Yehao Zhang, Gaojie Xin, Zixin Liu, Shujuan Xu, Xiao Han, Qiong Zhang, Jianhua Fu

“…Methods The I/R model was prepared by ligating the left anterior descending coronary artery for 45 min and then releasing the blood flow for 150 min. 96 male Wistar rats were randomly divided into sham group, I/R group, Hebeishuang group (HBS), SYI high-dose group (I/R + SYI-H), SYI medium-dose group (I/R + SYI-M) and SYI low-dose group (I/R + SYI-L). …”
Get full text

Internal Facilitation by Health Assistants for the “WHO Lay Health Worker Dementia Care” in Rural Uganda: A Formative Evaluation by Wakida EK, Obua C, Rukundo GZ, Samantha M, Maling S, Karungi CK, Talib ZM, Haberer J, Bartels SJ

“…Edith K Wakida,1,2 Celestino Obua,2 Godfrey Zari Rukundo,3 Mary Samantha,2 Samuel Maling,4 Christine K Karungi,2 Zohray M Talib,1 Jessica Haberer,5,6 Stephen J Bartels5,6 1Department of Medical Education, California University of Science and Medicine, Colton, California, USA; 2Department of Research and Development, Alpha Center for Research Administration, Mbarara, Uganda; 3Department of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton, Ontario, Canada; 4Department of Psychiatry, Mbarara University of Science and Technology, Mbarara, Uganda; 5Department of Internal Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA; 6Harvard Medical School, Harvard University, Boston, Massachusetts, USACorrespondence: Edith K Wakida, Email Edith.Wakida@cusm.eduBackground: Dementia is characterized by cognitive symptoms like memory loss, difficulty with language, and impaired judgment, alongside behavioral and psychological symptoms such as depression, anxiety, and aggression. …”
Get full text

The Lived Experience of Adult Cancer Survivors After Hematopoietic Stem Cell Transplantation: A Qualitative Study From Saudi Arabia by Almutairi H, Aboshaiqah A, Alzahrani M, Almutairi AF, Salam M

“…Inductive thematic analysis was conducted by two research team members.Results: Seven male and four female participants were interviewed (range of age 18 to 51 years). …”
Get full text

The Role of Mature Brain-Derived Neurotrophic Factor and Its Precursor in Predicting Early-Onset Insomnia in Stroke Patients Experiencing Early Neurological Deterioration by Shi G, Yu P, Wang Z, Xu M, Guo M, Wang X, Zhou R

“…Multivariate logistic regression analysis revealed that male gender (p = 0.026), Hamilton Depression Rating Scale (HAMD) scores (p < 0.001), mBDNF (p = 0.009), and the mBDNF/proBDNF ratio (p < 0.001) were independent predictors of EOI in END patients. …”
Get full text

Patterns of beta-blocker use and dose optimization among ambulatory heart failure patients with reduced ejection fraction (HFrEF) attending public hospitals in Northeast Ethiopia:... by Minimize Hassen, Tsehaynesh Kebede Ebsa, Oumer Sada Muhammed, Tewodros Solomon, Mulat Belete Demessie, Teklehaimanot Fentie Wendie, Nuhamin Alemayehu Tesfaye, Mengistie Yirsaw Gobezie

“…Factors positively associated with beta-blocker use included Angiotensin Converting Enzyme Inhibitor use (AOR: 15.48, 95% CI: 2.11-113.54, p = 0.007), and taking multiple medications (AOR: 7.12, 95% CI: 1.54–33.02, p = 0.012), while ingestion of secondary prevention agents (AOR: 0.05, 95% CI: 0.01–0.98, p = 0.048) and male gender (AOR: 0.08, 95% CI: 0.01–0.47, p = 0.005) were negatively associated. …”
Get full text

Evaluation of Lacrimal Punctal Changes by Anterior Segment Optical Coherence Tomography after Punctal Dilation Versus Punctal Plug Insertion in Cases of Inflammatory Punctual Steno... by Islam Awny, Elshimaa A Mateen Mossa, Tasneem Mohammed Bakheet, Hany Mahmoud, Amr Mounir

“…Both groups were comparable regarding mean age (39 ± 11 vs 50 ± 12 years, P value = 0.4) and sex (males were 36% vs 40%, female were 64% vs 60%, P value = 0.5) respectively with no statistically significant difference between both groups. …”
Get full text

Clinical features and predictors of atrial fibrillation in patients with light‐chain or transthyretin cardiac amyloidosis by Maria Papathanasiou, Aiste‐Monika Jakstaite, Sara Oubari, Johannes Siebermair, Reza Wakili, Julia Hoffmann, Alexander Carpinteiro, Tim Hagenacker, Andreas Thimm, Christoph Rischpler, Lukas Kessler, Tienush Rassaf, Peter Luedike

“…Mean age was 71 years, and 80% were male patients. AF was diagnosed in 64 (48%) patients (28% in AL‐CA, 80% in wtATTR, 13% in hATTR, P < 0.001). …”
Get full text

Investigating knowledge and attitudes toward genetic testing and counseling among palestinians by Mustafa Ghanim, Maha Rabayaa, Malik Alqub, Ahmad Hanani, Mohammad Abuawad, Belal Rahhal, Shurouq Qadous, Myassar Barahmeh, Sameeha Atout, Saad Al-Lahham, Aseel Aref, Majdi Dwikat, Samar Alkhaldi, Ahmad Makhamreh

“…A total of 1056 participants (408 males and 648 females) completed the questionnaire. …”
Get full text

Depression symptom severity and behavioral impairment in school-going adolescents in Uganda by Ronald Anguzu, Catherine Abbo, Julia Dickson-Gomez, Max Bobholz, Arthur Kiconco, Abdul R. Shour, Richard Kabanda, Kenneth Kalani, Laura D. Cassidy

“…PRR 1.27, 95%CI 1.12, 1.43) compared to males, taking alcohol (Adj. PRR 1.42, 95%CI 1.25, 1.61) compared to not taking alcohol, boarding school enrollees (Adj. …”
Get full text

Biologic Therapy and Cardiometabolic Risk in Psoriasis: A Retrospective Review by Annika Smith, Aidin Karahasan, Deborah Yi, Sanjay Yapabandara, James Elhindi, Pablo Fernandez-Penas, Clara Chow, Sarah Zaman

“…Of the 39 participants, 31 (79.5%) were male, 8 (20.5%) were female; 26 (67%) were biologic experienced (BE) and 13 (33%) were biologic naïve (BN). …”
Get full text

Efficacy analysis of pancreatic duct stenting in treating severe acute pancreatitis: a retrospective study by Liangping Chen, Ning Wang, Weijie Yao, Chengsi Zhao, Jiahang Tao, Gubai Ma, Chengwang Ma, Zuozheng Wang

“…A total of 51 patients were included (33 males, 18 females). Patients were divided into two groups based on treatment: the control group (n = 28) receiving conventional treatment and the stent group (n = 23) undergoing pancreatic duct stenting in addition to conventional treatment. …”
Get full text

Prevalence and factors associated with childhood malaria and anaemia in Osun state, Nigeria: a baseline household malariometric study by Olusola Ajibaye, Semiu Adebayo Rahman, Oluwagbemiga Olanrewaju Aina, Chinazo Ujuju, Chimere Obiora Agomo, Samuel Akindele, Olakiigbe Abiodun, Tolulope Victoria Uzoka, Nnenna Ogbulafor, Olufemi Oroge, Rufai-Ahmed Garba, Michael Ekholuenetale, Kolawole Maxwell, Ridwan Akorede Awosanya, Mary Abosede Adekola, Benjamin Bukky Ilesanmi, Adekemi Ajayi, Olusola Oresanya, James K. Tibenderana, Adeola Yetunde Olukosi

“…Female children were 51.8% and their male counterparts 48.2% respectively. Malaria positivity rate by RDT was 36.8% and this was higher in children aged 13–18 months (48.0%) and followed by those aged 7–12 months (44.0%). …”
Get full text

Syncopes and clinical outcome in heart failure: results from prospective clinical study data in Germany by Djawid Hashemi, Moritz Blum, Meinhard Mende, Stefan Störk, Christiane E. Angermann, Sabine Pankuweit, Elvis Tahirovic, Rolf Wachter, Burkert Pieske, Frank Edelmann, Hans‐Dirk Düngen, the German Competence Network for Heart Failure

“…Further analyses showed that among patients with HFrEF with HoS, known cardiovascular risk factors (e.g. age, male sex, diabetes mellitus, and anaemia) were more prevalent. …”
Get full text

Association of dietary quality and mortality in the non-alcoholic fatty liver disease and advanced fibrosis populations: NHANES 2005–2018 by Xingyong Huang, Xiaoyue Zhang, Xuanyu Hao, Tingting Wang, Peng Wu, Lufan Shen, Yuanyuan Yang, Wenyu Wan, Wenyu Wan, Wenyu Wan, Kai Zhang

“…Subgroup analyses revealed an interaction between AHEI scores and sex among NAFLD patients, where higher AHEI scores correlated with lower all-cause mortality in females, but no such association was observed in males. For other dietary quality, subgroup analyses indicated that their relationships with mortality were robust.ConclusionOur study suggests that a high-quality diet could potentially mitigate mortality risk in both NAFLD and advanced fibrosis patients.…”
Get full text

The association between controlling nutritional status and postoperative pulmonary complications in patients with colorectal cancer by Yafang Li, Chuang Nie, Na Li, Jieying Liang, Ning Su, Chunhua Yang

“…All-cause mortality was significantly higher in moderate-to-severe malnutrition group than that in normal nutrition group, HR: 1.88, (95% CI: 1.34–2.62, p &lt; 0.001). Older age, male sex, chronic heart disease, open surgery, blood transfusion during surgery, distant metastasis of tumor and colon tumor were all risk factors for PPCs. …”
Get full text

The triglyceride-glucose index trajectories are associated with cardiovascular diseases in people living with HIV: evidence from a prospective cohort study in China, 2005–2022 by Yinsong Luo, Liqin Sun, Yun He, Fang Zhao, Duo Shan, Fan Bu, Lingyun Ge, Xiaorui Li, Yiyao Hu, Xi Xiao, Hongzhou Lu, Jiaye Liu

“…These findings underscore the TyG index as a valuable marker for CVD risk assessment in PLWH, particularly in male populations. Incorporating TyG index monitoring into routine clinical assessments could enhance risk stratification and inform tailored prevention strategies. …”
Get full text

Time-dynamic associations between symptom-related expectations, self-management experiences and somatic symptom severity in everyday life: an ecological momentary assessment study... by Bernd Löwe, Yvonne Nestoriuc, Anne Toussaint, Stefanie Hahn, Franz Pauls, Simon Kirchhof

“…Multilevel mixed-effects linear regression analyses were conducted for data analysis.Setting Data was collected in real-time from university students via smartphones, with three predetermined assessments per day over seven consecutive days.Participants A total of 104 students (63.5% male, 0% diverse) who were 18 years or older, possessing sufficient German language skills and had access to an Android-powered smartphone were included.Interventions Participants were randomised to one of two different expectation framing groups, either receiving questionnaires for the expected impairment due to somatic symptoms (negative framing) or for the expected freedom from impairment due to somatic symptoms (positive framing).Primary outcome measures Somatic symptom severity was assessed using an adapted version of the Patient Health Questionnaire, with 11-point instead of 3-point Likert-scales. …”
Get full text

Hubungan antara Proteinuria dan Hipoalbuminemia pada Anak dengan Sindrom Nefrotik yang Dirawat di RSUP Dr. M. Djamil Padang periode 2009-2012 by Pratiwi Dian Pramana, Mayetti Mayetti, Husnil Kadri

“…The result of this study showed that the highest incidence of Nephrotic Syndrome in the age group &gt;6 years old especially in male with the ratio 1,43:1. Most of patients have levels of semiquantitative urinary protein +3 with average levels of quantitative urinary protein 3.121 ± 2.157 gr/24 hours. …”
Get full text