Managing xylazine-involved overdoses in a community harm reduction setting: lessons from Tijuana, Mexico by Lilia Pacheco Bufanda, Alejando González Montoya, Brenda Torres Carrillo, Mariana Alejandra Gonzalez Tejeda, Luis A. Segovia, Alhelí Calderón-Villarreal, Joseph R. Friedman

“…The third patient is a 36-year-old male who was found down, saturating at 20%, who received 0.4 mg intramuscular naloxone, was placed in recovery position, and remained unconscious for 12 min before making a complete recovery. …”
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Chemical Composition of Mexicali Propolis and Its Effect on Gastric Repair in an Indomethacin-Induced Gastric Injury Murine Model by Pilar Dominguez-Verano, Nadia Jacobo-Herrera, Andrés Castell-Rodríguez, Octavio Canales-Alvarez, Maria Margarita Canales-Martinez, Marco Aurelio Rodriguez-Monroy

“…Gastric injury was induced in male C57BL/6 mice by intragastric administration of indomethacin (10 mg/kg). …”
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Traditional pediatric massage enhanced the skeletal muscle mass in OVA-exposed adolescent rats via regulating SCFAs-FFAR2-IGF-1/AKT pathway by Lin Lin, Siyuan Li, Que Liu, Xingxing Zhang, Ying Xiong, Shaoyun Zhao, Liyue Cao, Jiaxuan Gong, Yaping Liu, Rong Wu

“…ObjectiveThis study aimed to investigate the potential relation between the retarded growth of skeletal muscle (SM) and dysbiosis of gut microbiota (GM) in children with asthma, and to explore the potential action mechanisms of traditional pediatric massage (TPM) from the perspective of regulating GM and short-chain fatty acids (SCFAs) production by using an adolescent rat model of asthma.MethodsMale Sprague-Dawley rats aged 3weeks were divided randomly into the 5 groups (n=6~7) of control, ovalbumin (OVA), OVA + TPM, OVA + methylprednisolone sodium succinate (MP) and OVA + SCFAs. …”
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Developing a youth-friendly internet-enabled HIV risk calculator: A collaborative approach with young key populations, living in Soweto, South Africa. by Mamakiri Mulaudzi, Gugulethu Tshabalala, Stefanie Hornschuh, Kofi Ebenezer Okyere-Dede, Minjue Wu, Oluwatobi Ifeloluwa Ariyo, Janan J Dietrich

“…Of the 40 enrolled participants, 58% were male, the median age was 20 (interquartile range 19-22.75), and 86% had access to the internet. …”
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Trends in incidence and mortality of prostate cancer in Ningbo City from 2011 to 2023 by ZHANG Qun，WANG Yong，CHEN Jieping，BAO Kaifang，FENG Yueyi，Wang Xiaoli

“…Special attention should be paid to urban residents, and prostate cancer screening should be strengthened among males aged 50 years and older.…”
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Global regional and national burden of intracerebral hemorrhage between 1990 and 2021 by Zhao-wei Wang, Mei-ping Wan, Jia-hui Tai, Yong Wang, Min-yi Yin

“…Gender analysis identified distinct age-specific patterns, with males above 35 showing higher risk, particularly in Eastern Europe, while South Asia demonstrated minimal gender differences. …”
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Intelligent measurement of adolescent idiopathic scoliosis x-ray coronal imaging parameters based on VB-Net neural network: a retrospective analysis of 2092 cases by Jinlong Liu, Haoran Zhang, Pei Dong, Danyang Su, Zhen Bai, Yuanbo Ma, Qiuju Miao, Shenyu Yang, Shuaikun Wang, Xiaopeng Yang

“…Results The differences in CA, CBD, CV, RSH, TI tilt, PT, LLD and SS were statistically significant between male and female genders (p < 0.05); Differences in CA, CBD, T1 Tilt, PT, SS, AVT and TS were statistically significant in patients with AIS of different severity (p < 0.001), and T1 Tilt, AVT, TS were risk factors; Differences in CA, CBD, CV, RSH, T1 Tilt, PT, LLD, SS, AVT and TS were statistically significant (p < 0.05) in patients with AIS of different curve types, and TS was a risk factor; Analyzing the correlation between parameters revealed a highly linear correlation between CV and RSH (r = 0.826, p < 0.001), and a significant linear correlation between CBD and TS, and PT and SS (r = 0.561, p < 0.001; r = 0.637, p < 0.001). …”
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Dentoskeletal effects of aesthetic and conventional twin block appliances in the treatment of skeletal class II malocclusion: a randomized controlled trial by Mohamed Najati Alsilq, Mohamed Youssef

“…Fifty-two patients (33 females and 19 males) aged 12.23 ± 0.77 years with skeletal class II division 1 malocclusion caused by mandibular retrognathism were included. …”
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Assessing the development of health technology assessment in Iran: a policy analysis using Kingdon’s Multiple streams framework: a qualitative study by Meysam Behzadifar, Saeed Shahabi, Ahad Bakhtiari, Samad Azari, Seyed Jafar Ehsanzadeh, Mohammad Yarahmadi, Masoud Behzadifar

“…Participants, consisting of 12 males and 4 females with an average age of 41.56 years and an average work experience of 14.37 years, provided insights into the current state of HTA. …”
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Accuracy of Rhythm Diagnostic Systems’ MultiSense^® in Detection of Arterial Oxygen Saturation and Respiratory Rate During Hypoxia in Humans: Effects of Skin Color and De... by Charles Evrard, Amina El Attaoui, Cristina Pistea, Irina Enache, Mark Marriott, Louis Mayaud, Anne Charloux, Bernard Geny

“…In a population of sixteen healthy male subjects (mean age: 31.5 ± 7.0 years, BMI: 24.9 ± 3.6 kg/m², and 35% with darker skin tones), simultaneous SpO₂ and RR measurements were collected over 12.4 h, during which FiO₂ was progressively reduced from 21% to 10.5%. …”
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Understanding Individual Differences in Happiness Sources and Implications for Health Technology Design: Exploratory Analysis of an Open Dataset by Edel Ennis, Raymond Bond, Maurice Mulvenna, Colm Sweeney

“…ResultsSex and age interacted to influence what was selected as sources of happiness, with patterns being less consistent among female individuals in comparison with male individuals. For marital status, differences in sources of happiness were predominantly between married individuals and those who are divorced or separated, but these were the same for both sexes. …”
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Signs of Nervous System Sensitization in Female Runners with Chronic Patellofemoral Pain by Brian J. Eckenrode, David M. Kietrys, Allison Brown, J. Scott Parrott, Brian Noehren

“…# Background Patellofemoral pain (PFP) is a common overuse injury among runners, affecting females at a higher rate than males. PFP can often become chronic, with evidence suggesting it may be linked to both peripheral and central sensitization of the nervous system. …”
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Assessing awareness and treatment knowledge of preventable blindness in rural and urban South African communities by Z Kiva, J E Wolvaardt

“…Both groups had a similar composition of males and females. Most participants had completed high school. …”
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A prospective multi-site study to evaluate the performance and usability of an oral fluid-based HIV self-test in Canada by Richard A. Galli, Darshanand Maraj, Kristin McBain, Jason M. Lo Hog Tian, Abbey McFarland, Wangari Tharao, Nontobeko P. Nkala, Arlene Chan, Mark da Silva, Rejean Thomas, Anne-Fanny Vassal, Martin Lepage, Laurie Ireland, Mike Payne, Jared Starr, Chris Fraser, Marion Selfridge, Mona Loutfy, Roberta Halpenny, Nirubini Jeyarajah, Vanessa Tran, Tony Mazzulli, Sean B. Rourke

“…With respect to sociodemographics: 84% of participants were between 18–45 years of age, 73% had at least a college education, 48% were Cis-male, 45% were employed; and 26% identified as White, 23% as African, Caribbean or Black, 5% as Indigenous [First Nations, Métis or Inuit], 33% as Asian, and 6% as LatinX. …”
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A Retrospective Study on Correlation of Facial Fractures and Type of Trauma in Patients Admitted in Department of Maxillofacial Surgery of Stomatology National and Specialized Hosp... by Sharif AK, Ehsan H, Mirzad SW, Ibrahimkhil MA

“…Statistical analysis was performed to identify patterns and correlations.Results: The study included 463 patients (378 males and 85 females), aged between 3 and 88 years, with a mean age of 26.34 years. …”
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Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3 by Han Chu, Qi-Fei Deng, Yuan Fang

“…Research indicates that vitamin D enhances sperm quality in adult males. This study aimed to explore whether vitamin D inhibits NLRP3 activation, thus helping to mitigate heat stress damage to testicular spermatogenic and Sertoli cells.Materials and methodsFive cases of normal testicular tissue adjacent to a tumor (testis removed due to tumorous growth) and five cases of atrophied cryptorchid testicular tissue (testis removed) were analyzed for immunohistochemistry to determine NLRP3 expression in cryptorchid tissue. …”
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Low handgrip strength with asymmetry is associated with elevated all-cause mortality risk in older Chinese adults with abdominal obesity. by Ling Wei, Binyou Wang, Yilin Wang

“…<h4>Results</h4>A total of 5186 subjects aged 60 years or older were enrolled, 50.6% of whom were male. The proportions of participants with only AO, only low HGS, only HGS asymmetry, low HGS with asymmetry, both AO and low HGS, both AO and asymmetric HGS, and AO with both low HGS and asymmetry were 20.0%, 6.1%, 16.6%, 8.3%, 3.2%, 13.4%, and 3.9%, respectively. …”
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Interventional effects of different track and field sports on human cardiovascular function indicators and physiological energy metabolism by Ruibin Jing, Zhengwei Wang, Choi Mee-Seong

“…Method The research subjects were ordinary male students majoring in physical education at a certain university, aged between 18 and 25 years old. …”
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The associations of physical activity patterns and the triglyceride-glucose index in US adults: a secondary data analysis of NHANES (2007–2018) by JinYe Zhang, YiLin Yang, HaoNan Zheng, BoWen Bai, QianKun Yang, Li Zhang, YuTong Zhao, Jing Luo, Bin Yu

“…Stratified analyses and interact tests revealed that the PA-TyG index association in RA group was more pronounced in individuals being male, with higher education levels, and without diabetes. …”
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Correlation between Apelin and Some Angiogenic Factors in the Pathogenesis of Preeclampsia: Apelin-13 as Novel Drug for Treating Preeclampsia and Its Physiological Effects on Place... by Reham Z. Hamza, Abdel Aziz A. Diab, Mansour H. Zahra, Ali K. Asalah, Suzan M. M. Moursi, Najah M. Al-Baqami, Fawziah A. Al-Salmi, Mai S. Attia

“…This study was formulated to assess the serum apelin level in PE, investigate its correlation with some inflammatory, oxidative stress, and angiogenic proteins in a nitric oxide synthase inhibitor; the N (gamma)-nitro-L-arginine methyl ester (L-NAME)-induced rat model of PE and determine whether apelin administration could protect against development of PE. 40 healthy adult female albino rats and 10 adult male albino rats were used in this study. The pregnant female rats were randomly divided into three groups: group 1 (normal pregnant group), group 2 (PE-induced group), injected subcutaneously with 75 mg L-NAME/kg bodyweight/day starting from day 9 to 20 of gestation, and group 3 (PE-induced group supplemented with apelin (PE + apelin)); PE induced as before and simultaneously subcutaneously injected with apelin-13 (6 × 10−8 mol/kg bodyweight/twice daily) beginning from day 6 to 20 of gestation. …”
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