How does individualised physiotherapy work for people with low back pain? A Bayesian Network analysis using randomised controlled trial data. by Bernard X W Liew, Jon J Ford, Marco Scutari, Andrew J Hahne

“…<h4>Methods</h4>300 randomised controlled trial participants (153 male, 147 female, mean age 44.1) with low back pain (of duration 6-26 weeks) received either individualised physiotherapy or advice. …”
Get full text

Tofogliflozin attenuates renal lipid deposition and inflammation via PPARα upregulation mediated by miR-21a impairment in diet-induced steatohepatitic mice by Sae Nishihara, Masahiro Koseki, Katsunao Tanaka, Takashi Omatsu, Ayami Saga, Hiroshi Sawabe, Hiroyasu Inui, Takeshi Okada, Tohru Ohama, Daisuke Okuzaki, Yoshihiro Kamada, Masafumi Ono, Makoto Nishida, Mikio Watanabe, Yasushi Sakata

“…Therefore, we used this model to evaluate the effects of tofogliflozin on renal lipid metabolism and inflammation. Male 8–10-week-old C57Bl/6 mice were fed a high-fat/high-cholesterol/high-sucrose/bile acid (HF/HC/HS/BA) diet with 0.015% tofogliflozin (Tofo group) or an HF/HC/HS/BA diet alone (SLD group). …”
Get full text

Analysis of factors influencing HPV vaccination intention among Chinese college students: structural equation modeling based on health belief theory by Shi-Yuan Song, Ying Guo, Yi-Hua Li, Zheng Wang, Wei Gao

“…In terms of health attitudes, the positive intention rate was 50.4%, with females having more positive attitudes than males (OR = 2.242, 95% CI = 1.777–2.829). In terms of health behaviors, the rate of positive behaviors was low (40.0%), and the probability of positive behaviors was significantly lower for students with nonmedical-related majors than for those with medical majors (OR = 0.579, 95% CI = 0.442–0.759). …”
Get full text

Burnout Syndrome among Emergency Physicians and Nurses in Abha and Khamis Mushait Cities, Aseer Region, Southwestern Saudi Arabia by Abdulghani M. Alqahtani, Nabil J. Awadalla, Safar A. Alsaleem, Awad S. Alsamghan, Mohammed Abadi Alsaleem

“…Multivariate logistic regression analysis revealed that male healthcare professionals were at almost higher three-folded risk for developing burnout compared to females (aOR=2.76; 95% confidence interval (CI): 1.21-6.28, p=0.017)). …”
Get full text

Tear glucose is associated with the presence and severity of diabetic retinopathy by Ningyao Cao, Lili Feng, Wei Xu, Fanglin He, Caiwen Xiao, Yan Liu, Weirong Xu, Jingjing Cui, Yuqian Guo, Lianqing Yao, Wenwen Xia, Fei Chen, Yong Li, Chuandi Zhou, Xiaofang Xu

“…Results In this study, 160 patients were included, with a median age of 64.0 years, and 88 (55.0%) patients were males. A total of 91 (56.9%) patients had positive TG, and 69 (43.1%) patients had negative TG. …”
Get full text

Acute haemodynamic impact of transcatheter aortic valve implantation in patients with severe aortic stenosis by Francesca Graziani, Pio Cialdella, Rosa Lillo, Gabriella Locorotondo, Lorenzo Genuardi, Gessica Ingrasciotta, Stefano Cangemi, Marialisa Nesta, Piergiorgio Bruno, Cristina Aurigemma, Enrico Romagnoli, Michele Calabrese, Nicole Giambusso, Antonella Lombardo, Francesco Burzotta, Carlo Trani

“…Methods and results A total of 245 consecutive AS patients (43% male, mean age 80.3 ± 7.3 years) undergoing TAVI were enrolled. …”
Get full text

Efficacy, safety, and biomarker analysis of TACE combined with lenvatinib plus sintilimab in unresectable hepatocellular carcinoma: a real-world study by Lingzhan Meng, Hu Li, Yingjie Ji, Peng Yu, Zizheng Wang, Li Cao, Bin Shi, Yanling Shao, Jin Yan, Yinjie Gao, Zhenyu Zhu

“…Results The study included 70 patients with unresectable HCC, predominantly male and infected with Hepatitis B. The median follow-up duration for the whole cohort was 13.8 months (95% CI 11.08–16.7). …”
Get full text

Abnormal Liver Tests during Hospitalization Predict Mortality in Patients with COVID-19: A Multicenter Study from South America by Domingo Balderramo, Angelo Z. Mattos, Victoria Mulqui, Talita Chiesa, Zuly Plácido-Damián, Jaysoom Abarca, Andrea Bolomo, Yanina Carlino, Isadora Z. Bombassaro, Denusa Wiltgen, Laura Tenorio Castillo, Karina Díaz, Johana Acuña, Estela Manero, Jhon Prieto, Enrique Carrera, Javier Díaz-Ferrer, Jose D. Debes

“…Of the total of 298 patients, 60% were male, with a mean age of 60 years, and 74% of patients had at least one comorbidity. …”
Get full text

Causal association of sex hormone-related traits with Alzheimer’s disease: a multivariable and network Mendelian randomization analysis by Yan Zhang, Zhen-dong Sun, Yu-shen Yang, Wei-dong Fu

“…There is no evidence of a causal association of SHBG [ORs (95% CI), 1.002 (0.999–1.005)), p = 0.237] and testosterone [ORs (95% CI), 1.000 (0.997–1.004), p = 0.810] with AD in males. Multivariate MR analysis revealed a possible direct causal connection between SHBG and testosterone in relation to females AD (SHBG-OR (95%CI), 1.005 (1.001–1.009, p = 0.023); testosterone-OR (95%CI), 0.995 (0.989–1.000, p = 0.049). …”
Get full text

Task-Driven Neurophysiological qEEG Baseline Performance Capabilities in Healthy, Uninjured Division-I College Athletes. by Robert E. Mangine, Thomas G. Palmer, James A. Tersak, Michael Mark, Joseph F Clark, Marsha Eifert-Mangine, Audrey Hill-Lindsay, Brian M Grawe

“… # Methods Twenty-eight healthy uninjured females (n=11) and males (n=17) NCAA Division-I athletes participated in real-time neurophysiological assessment using a Bluetooth, wireless 21-channel dry EEG headset while performing functional activities…”
Get full text

Validity and Reliability of Upper Limb Functional Assessment Using the Microsoft Kinect V2 Sensor by Laisi Cai, Ye Ma, Shuping Xiong, Yanxin Zhang

“…Approach. Ten healthy males performed a series of upper limb movements, which were measured concurrently with Kinect V2 and the Vicon motion capture system (gold standard). …”
Get full text

Prevalence of unexpected red blood cell antibodies in pregnant women and follow-up of pregnancy outcome in pregnant women treated with intra-uterine transfusion by Sunil Golia, Aseem Kumar Tiwari, Geet Aggarwal, Anil Khetrapal, Sandeep Kumar Tyagi, Chetna Jain, Shubham Gupta, Samruddhi Pawar

“…In both these cases, healthy male child was delivered. At 3-month follow-up both children were alive and healthy. …”
Get full text

Quadriceps and Hamstrings Activation Peaks Earlier as Athletes Repeatedly Hop, but There are Differences Depending on ACL Reconstruction Technique. by Einar Einarsson, Olivia Barbosa, Magnus Kjartan Gislason, Kristin Briem, Argyro Kotsifaki, Rodney Whiteley

“… # Methods Surface electromyography (SEMG) was recorded from vastus medialis and lateralis and medial and lateral hamstrings bilaterally during 30 seconds' repeated hopping in male athletes on average eight months after ACLR surgery (5-12 months). …”
Get full text

Prognostic factors for head and neck cancer of unknown primary including the impact of human papilloma virus infection by Lars Axelsson, Jan Nyman, Hedda Haugen-Cange, Mogens Bove, Leif Johansson, Shahin De Lara, Anikó Kovács, Eva Hammerlid

“…The mean age was 59 years. The majority were males, and had N2 tumors. Sixty-nine percent of the tumors were HPV positive using p16 staining. …”
Get full text

Accidental findings of maxillary sinuses in dental patients on CBCT images. A retrospective study by Fedil Andraws Yalda

“…Result: Out of 255 patients, 148 (58%) were males and 107 (42%) were females with a mean age of 50.23 (SD=19.08). …”
Get full text

Outcomes of oncologic arthroplasty in children and adolescents with malignant limb tumors: a systematic review by Vyacheslav I. Zorin, Sergei V. Vissarionov, Alexandr Y. Makarov, Timofey S. Rybinskikh, Kristina N. Rodionova

“…The review included the data from 30 articles on a total of 792 patients aged 2 to 18 years, with 422 males and 370 females. The average age was 11.4 years, and the average follow-up period was 6.5 years. …”
Get full text

Effects of Teriparatide on Bone Mineral Density and Prevention of Fragility Fractures in Saudi Arabian Subjects with Osteoporosis: A Two-Year Clinical Study from a Single Center by Mir Sadat-Ali, Abdallah Al-Omran, Khalid AlTabash, Dakheel A. AlDakheel, Salma Elansassy, Tarek Hegazi, Mona Al Muhaish

“…Three hundred and sixty-five patients (87.9%) were females, and the rest were males. The average age was 68.21 ± 17.6 years. Two hundred and forty-eight patients (59.8%) were treatment naïve, and 167 (40.2%) were on treatment for osteoporosis. …”
Get full text

Preconception Care Uptake and Immediate Outcomes among Discordant Couples Accessing Routine HIV Care in Kenya by Nyawira Gitahi, Sheila Juliet Eshiwani, Kenneth Mutai, Jared Ongechi Mecha, James Njogu Kiarie

“…Results. Among couples, with male HIV-positive partners, there was a twofold likelihood of accepting preconception services (OR = 2.3, CI 95% (1, 1, 5.0)). …”
Get full text

Association of Sociodemographic Factors With Overtriage, Undertriage, and Value of Care After Major Surgery by Tyler J. Loftus, MD, Matthew M. Ruppert, MS, Benjamin Shickel, PhD, Tezcan Ozrazgat-Baslanti, PhD, Jeremy A. Balch, MD, Kenneth L. Abbott, MD, Die Hu, MS, Adnan Javed, MD, Firas Madbak, MD, Faheem Guirgis, MD, David Skarupa, MD, Philip A. Efron, MD, Patrick J. Tighe, MD, William R. Hogan, MD, Parisa Rashidi, PhD, Gilbert R. Upchurch, Jr, MD, Azra Bihorac, MD

“…Compared with controls, overtriaged admissions had a predominance of male patients (56.2% vs 43.1%, P < 0.001) and commercial insurance (6.4% vs 2.5%, P < 0.001); undertriaged admissions had a predominance of Black patients (28.4% vs 24.4%, P < 0.001) and greater socioeconomic deprivation. …”
Get full text

PrEP15-19 Choices: an implementation study protocol of HIV prevention with oral and long-acting injectable cabotegravir PrEP in real-world settings among sexual and gender minority... by Inês Dourado, Eliana Miura Zucchi, Laio Magno, Alexandre D Grangeiro, Márcia Thereza Couto, Mateus Westin, Eduardo Oliveira, Maria Mercedes Escuder, Dirceu Greco, Thais Regis Aranha Rossi, Fabiane Soares, Lorenza Dezanet, Paula Massa, Priscilla Caires, Ricardo de Paula Vasconcelos, Unaí Tupinambas, Beo Leite, Joilson Nascimento Paim, Guilherme Barreto Campos, Lucas Miranda Marques, Nathalia Suzart, Suilan Pedreira, DulceAurélia deSouza Ferraz, Dyemison Pinheiro, Eliane Sala, Raphaella Goulart, Ana Paula Silva, Erica Dumont Pena, Gabriella Jomara daSilva, Marília Greco, Matheus dePaula Alves

“…The study will include a sample of 550 HIV-negative adolescent men who have sex with men, non-binary individuals assigned male at birth, transgender men and women, aged 15–19 years, in three Brazilian capital cities. …”
Get full text