Intramedullary Fixation for Metacarpal Fractures: A Multi-Institutional Prospective Outcomes Study by Michael B. Gehring, MD, Brandon Wolfe, BA, Riley Kahan, BS, Stephanie D. Malliaris, MD, Kia M. Washington, MD, Matthew D. Folchert, MD, Kyros Ipaktchi, MD, Mark A. Greyson, MD, Alexander Lauder, MD, Matthew L. Iorio, MD

“…Results: One-hundred-one fractures were treated in 82 patients with an average age of 33 years and mean follow-up of 69 days. Most patients were male (70%), nonlaborers (72%), and nonsmokers (74%). …”
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Aroma Analysis of Table Grape Berries Based on Electronic Nose Detection by Shengyang Niu, Xuewei Liu, Meiling Lin, Xiucai Fan, Ying Zhang, Lei Sun, Chonghuai Liu, Jianfu Jiang

“…This study not only provides a scientific basis for the variety selection for the table grape processing industry, but it can also be used for male or female grape hybridization, which provides valuable data resources for table grape breeding.…”
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Blockade of Erythropoietin-Producing Human Hepatocellular Carcinoma Receptor B1 in Spinal Dorsal Horn Alleviates Visceral Pain in Rats by Chen-Li Sun, Cheng-Wen Li, Nong He, Yuan-Zhang Tang, Xiu-Liang Li, Fu-Shan Xue, Jia-Xiang Ni

“…This experiment was designed to determine whether erythropoietin-producing human hepatocellular carcinoma (Eph) receptors were involved in the development of visceral pain. Methods. Adult male Sprague-Dawley rats were randomly divided into three groups receiving different treatments (n = 16 per group): intracolonic vehicle (control group), intracolonic 2, 4, 6-trinitrobenzene sulfonic acid (TNBS) (TNBS group), and intracolonic TNBS and intrathecal EphB1 receptor blocking reagent (TNBS + EphB2-Fc group). …”
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Age‐related longitudinal change in cardiac structure and function in adults at increased cardiovascular risk by Fei Fei Gong, Jennifer M. Coller, Michele McGrady, Umberto Boffa, Louise Shiel, Danny Liew, Simon Stewart, Alice J. Owen, Henry Krum, Christopher M. Reid, David L. Prior, Duncan J. Campbell

“…Median age was 71 (IQR 67, 76) years and 55% of participants were male. Age was associated with longitudinal increase in left ventricular (LV) mass index (LVMI); decrease in LV volumes; increase in LV ejection fraction; decrease in mitral annular systolic velocity; decrease in diastolic function (decreased mitral early diastolic annular velocity (e′); and increase in left atrial volume index, mitral peak early diastolic flow velocity (E)/e′ ratio, and tricuspid regurgitant velocity (TRVmax) in men and women, except for TRVmax in men). …”
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Comparative Study of Chikungunya Only and Chikungunya-Scrub Typhus Coinfection in Children: Findings from a Hospital-Based Observational Study from Central Nepal by Santosh Pathak, Nagendra Chaudhary, Prativa Dhakal, Sanjay Ray Yadav, Binod Kumar Gupta, Om Prakash Kurmi

“…Out of the 382 admitted cases with fever, 11% (n=42) were diagnosed with chikungunya, and the majority (n=30, 71.4%) were male. Among the 42 chikungunya cases, 17 (40.5%) tested positive for scrub typhus and one positive for falciparum malaria. …”
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The Impact of Thyme and Rosemary on Prevention of Osteoporosis in Rats by Amr S. Elbahnasawy, E. R. Valeeva, Eman M. El-Sayed, I. I. Rakhimov

“…The experiment was carried out on growing male Sprague–Dawley rats; the experimental animals were divided into 5 groups: 1, control negative was fed standard balanced diet; 2, control positive was fed balanced diet with low calcium level (L Ca) (Ca 0.1% w/w); 3, (L Ca) + thyme powder (5% w/w); 4, (L Ca) + rosemary powder (5% w/w); 5, (L Ca) + orally administration with CaCO3 (27 mg/kg body weight). …”
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Demographic disparities in unimproved drinking water and sanitation in Ghana: a nationally representative cross-sectional study by Felix Boakye Oppong, Divine Darlington Logo, Dennis Boateng, Ephraim Kumi Senkyire

“…In the multivariate analysis, rural households (p<0.001), households with more than five members (p<0.001), households with heads less than 25 years (p=0.018), male-headed households (p<0.001) and household heads with no/low level of education (p<0.001) were significantly associated with drinking unimproved water. …”
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The Efficacy and Safety of the Chinese Herbal Formula, JTTZ, for the Treatment of Type 2 Diabetes with Obesity and Hyperlipidemia: A Multicenter Randomized, Positive-Controlled, Op... by Xiaotong Yu, Lipeng Xu, Qiang Zhou, Shengping Wu, Jiaxing Tian, Chunli Piao, Hailong Guo, Jun Zhang, Liping Li, Shentao Wu, Meizhen Guo, Yuzhi Hong, Weirong Pu, Xiyan Zhao, Yang Liu, Bing Pang, Zhiping Peng, Song Wang, Fengmei Lian, Xiaolin Tong

“…A total of 450 participants with T2D (HbA1c ≥ 7.0%; waist circumference ≥ 90 cm and 80 cm in males and females, resp.; and triglycerides (TG) ≥ 1.7 mmol/L) were randomly assigned, in equal proportions, to two groups in this multicenter randomized, positive-controlled, open-label trial. …”
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Association between Comorbidities and Progression of Transvalvular Pressure Gradients in Patients with Moderate and Severe Aortic Valve Stenosis by Tim Salinger, Kai Hu, Dan Liu, Scharoch Taleh, Sebastian Herrmann, Daniel Oder, Daniel Gensler, Jonas Müntze, Georg Ertl, Kristina Lorenz, Stefan Frantz, Frank Weidemann, Peter Nordbeck

“…A total of 402 patients (mean age 78 ± 9.4 years, 58% males) were included in the study. Mean follow-up duration was 3.4 ± 1.9 years. …”
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The Effect of Lipotoxicity on Renal Dysfunction in a Nonobese Rat Model of Metabolic Syndrome: A Urinary Proteomic Approach by Irena Markova, Denisa Miklankova, Martina Hüttl, Petr Kacer, Jelena Skibova, Jan Kucera, Radislav Sedlacek, Tereza Kacerova, Ludmila Kazdova, Hana Malinska

“…In this study, we investigated the manifestation of renal lipid accumulation and its effect on renal dysfunction in a model of metabolic syndrome—the hereditary hypertriglyceridemic rat (HHTg)—by assessing microalbuminuria and targeted urinary proteomics. Male Wistar control rats and HHTg rats were fed a standard diet and observed over the course of ageing at 3, 12, and 20 months of age. …”
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Supplementation with Standardized Green/Black or White Tea Extracts Attenuates Hypertension and Ischemia-Reperfusion-Induced Myocardial Damage in Mice Infused with Angiotensin II by Mario de la Fuente-Muñoz, Marta Román-Carmena, Sara Amor, María C. Iglesias-de la Cruz, Patricia Martorell, Sonia Guilera-Bermell, Reme García Bou, Antonio M. Inarejos-García, Ángel L. García-Villalón, Miriam Granado

“…For this purpose, four groups of C57BL/6J male mice were used: (1) mice fed on a standard diet for 8 weeks and infused with saline for the last 4 weeks (controls); (2) mice fed on a standard diet for 8 weeks and infused with AngII for the last 4 weeks (AngII); (3) mice fed on a standard diet supplemented with 1.6% WTE and infused with AngII for the last 4 weeks (AngII + WTE); (4) mice fed on a standard diet supplemented with 1.6% TC and infused with AngII for the last 4 weeks (AngII + CTE). …”
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Scopoletin as a cardioprotective agent against cisplatin-induced oxidative stress and inflammation by Esam Qnais, Omar Gammoh, Yousra Bsieso, Mohammad Alqudah, Mohammad Wedyan, Sara Altaber, Alaa A.A. Aljabali, Abdelrahim Alqudah, Taher Hatahet

“…Study Design: A controlled experimental design was employed to evaluate scopoletin's efficacy in alleviating CP-induced cardiotoxicity, with dosing variations to assess dose dependency. Methods: Male mice were allocated into five groups: a control group, a cisplatin-only group, two groups treated with low (50 mg/kg/day) and high doses (150 mg/kg/day) of scopoletin in conjunction with cisplatin, and a scopoletin-only group. …”
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Evaluation of Radiological and Anatomical Features of Cervical Vertebrae in Adult Persian Cat by Peghah Derakhshi, Siamak Alizadeh, Mohammadreza Hosseinchi

“…Methods The present descriptive‐cross‐sectional study included 10 adult Persian cats, including 5 males and 5 females. All cats underwent radiography in the dorsoventral, ventrodorsal, left lateral and right lateral recumbency. …”
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Tuberculosis and Sudden Death in Lithuania by Gintarė Zarembaitė, Gabrielė Žiūkaitė, Sigitas Chmieliauskas, Diana Vasiljevaitė, Sigitas Laima, Jurgita Stasiūnienė

“…Results: The study revealed that out of 100 pulmonary tuberculosis cases, 90% were male with the mean age of 53.48 ± 11.12 years old. …”
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Effects of celastrol on the heart and liver galaninergic system expression in a mouse model of Western-type diet-induced obesity and metabolic dysfunction-associated steatotic live... by Nikolina Canová, Jana Šípková, Mahak Arora, Zuzana Pavlíková, Zuzana Pavlíková, Tomáš Kučera, Ondřej Šeda, Tijana Šopin, Tomáš Vacík, Ondřej Slanař

“…Therefore, this study aimed to investigate the effects of celastrol on the galaninergic system expression in the heart and liver of mice suffering from diet-induced obesity and metabolic dysfunction-associated steatotic liver disease and steatohepatitis (MASLD/MASH).MethodsThe male mice C57BL/6J were fed a Western-type high-fat diet for 16 and 20 weeks to induce obesity and MASLD/MASH. …”
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The Effects of TMR® Fab 6 on Hamstring Flexibility in Healthy Subjects; An Exploratory Observational Investigation by Richard D. Patterson, Alexander Zettlemoyer, Mary Plackowski, Russell Baker, Scott W. Cheatham, Alan Nasypany

“… # Study Design Observational Cohort study # Methods A convenience sample of 20 healthy participants (10 males, 10 females) were recruited from three institutions. …”
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Clinical and Hematological Manifestation of Dengue Patients in 2022 Outbreak: A Tertiary Care Hospital‐Based Cross‐Sectional Study by Md. Jubayer Hossain, Manisha Das, Muhibullah Shahjahan, Md. Wahidul Islam, Syeda Tasneem Towhid

“…Results Predominantly male patients (76%) aged 21−40 (63%) and middle‐class patients from Dhaka (57%) formed the majority. …”
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Reliability of the EasyAngle® for Assessing Hip Range of Motion in Healthy Children by Elana Duffy, Maria Wells, Alan Miller, Megan Tondra, Antonette Doty

“… # Results Twenty healthy children were measured (age 5-10, mean = 7.40 years old, SD = 1.37, 9 males, 11 females). Mean hip ROM was reported by age. …”
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Prevalence and correlates of burn-out among Nigerian medical doctors during the COVID-19 pandemic: a cross-sectional study by Ruth Eshikotse Pius, Janet Ngozi Ajuluchukwu, Alero Ann Roberts

“…Personal, work-related and patient-related burn-out were evaluated with the use of the Copenhagen Burnout Inventory.Results The number of doctors enrolled in this study was 251 with a median age of 34; 51.4% were males. The percentage of doctors who had personal, work-related and patient-related burn-out were 62.2%, 52.2 % and 27.5%, respectively. …”
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Effects of Anthocyanin and Flavanol Compounds on Lipid Metabolism and Adipose Tissue Associated Systemic Inflammation in Diet-Induced Obesity by Roel A. van der Heijden, Martine C. Morrison, Fareeba Sheedfar, Petra Mulder, Marijke Schreurs, Pascal P. H. Hommelberg, Marten H. Hofker, Casper Schalkwijk, Robert Kleemann, Uwe J. F. Tietge, Debby P. Y. Koonen, Peter Heeringa

“…We hypothesized that their effects on attenuating obesity-induced dyslipidemia as well as the associated inflammatory sequelae especially have health-promoting potential. Methods. Male C57BL/6J mice (n=52) received a control low-fat diet (LFD; 10 kcal% fat) for 6 weeks followed by 24 weeks of either LFD (n=13) or high-fat diet (HFD; 45 kcal% fat; n=13) or HFD supplemented with 0.1% w/w of the flavanol compound epicatechin (HFD+E; n=13) or an anthocyanin-rich bilberry extract (HFD+B; n=13). …”
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