Functional MRI Assessment of Task-Induced Deactivation of the Default Mode Network in Alzheimer’s Disease and At-Risk Older Individuals by Maija Pihlajamäki, Reisa A. Sperling

“…Alzheimer’s disease (AD) is the most common form of dementia in old age, and is characterized by prominent impairment of episodic memory. …”
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Identification of Potential Herbal Inhibitor of Acetylcholinesterase Associated Alzheimer’s Disorders Using Molecular Docking and Molecular Dynamics Simulation by Chandrabhan Seniya, Ghulam Jilani Khan, Kuldeep Uchadia

“…Additionally, acetylcholinesterase (AChE) is the target for many Alzheimer’s dementia drugs which block the function of AChE but have some side effects. …”
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Influence of immune cells and inflammatory factors on Alzheimer’s disease axis: evidence from mediation Mendelian randomization study by Linzhu, Jianxin Zhang, Wenhui Fan, Chen Su, Zhi Jin

“…Abstract Background Alzheimer’s disease (AD) is one of the most common forms of dementia in the elderly, characterized by progressive neurodegeneration. …”
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Interplay between oxidative stress, neuroinflammatory cytokines and melatonin in Alzheimer's disease: Insights from cerebrospinal fluid analysis by Francisco Artime-Naveda, David Hevia, Rebeca Alonso-Arias, Carmen Martínez, Isabel Quirós-González, Rafael Cernuda-Cernuda, Alejando Alvarez-Artime, Iván Menéndez-Valle, Rosa M. Sainz, Juan C. Mayo

“…Abstract: Background: Among neurodegenerative disorders Alzheimer's disease (AD) displays the highest prevalence and the projected increase in its incidence will require new advances in early diagnosis and treatment, particularly for distinguishing AD from other dementias. …”
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Kidney Function and Incident Stroke and Dementia Using an Updated Estimated Glomerular Filtration Rate Equation Without Race: The Multi-Ethnic Study of Atherosclerosis by Samuel R. Moen, Jeffrey R. Misialek, Timothy M. Hughes, Craig W. Johnson, Mark J. Sarnak, Sarah N. Forrester, W.T. Longstreth, Jr., Mercedes R. Carnethon, James S. Pankow, Sanaz Sedaghat

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A Middle-Aged Woman with Logopenic Progressive Aphasia as a Precursor of Alzheimer's Disease: Case Report and Review of the Literature by Stephanie M. Awad, Amer M. Awad

“…The logopenic variant is the least common one and is closely related to Alzheimer's disease in comparison to the other two variants that are closely related to frontotemporal dementia. …”
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Reduction of orexin-expressing neurons and a unique sleep phenotype in the Tg-SwDI mouse model of Alzheimer’s disease by Yan Wu, Narayan R. Bhat, Meng Liu

“…Sleep disturbances are common in Alzheimer’s disease (AD) and AD-related dementia (ADRD). …”
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Assessment of the Impact of Different Types and Intensities of Physical Exercise on the Quality of Life of Patients with Alzheimer’s Disease: A Literature Review by Katarzyna Barabasz, Paulina Więcławek, Piotr Juda, Patrycja Kłaptocz, Katarzyna Łukoś-Karcz, Dominik Bańkowski, Gabriela Pabian, Karol Musiał, Kamil Bielak

“… Objective Alzheimer’s Disease (AD) is the most common form of dementia, representing a global health challenge. …”
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Biomarker Investigation Using Multiple Brain Measures from MRI Through Explainable Artificial Intelligence in Alzheimer’s Disease Classification by Davide Coluzzi, Valentina Bordin, Massimo W. Rivolta, Igor Fortel, Liang Zhan, Alex Leow, Giuseppe Baselli

“…As the leading cause of dementia worldwide, Alzheimer’s Disease (AD) has prompted significant interest in developing Deep Learning (DL) approaches for its classification. …”
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Relationship between Urinary Alzheimer-Associated Neuronal Thread Protein and Apolipoprotein Epsilon 4 Allele in the Cognitively Normal Population by Yuxia Li, Meimei Kang, Can Sheng, Guanqun Chen, Taoran Li, Jun Wang, Yanning Cai, Rong Wang, Ying Han

“…Urinary AD7c-NTP levels were not related to years of education, nature of work, family history of dementia, a history of hypertension, stroke, anemia, or thyroid dysfunction. …”
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Exome sequencing reveals a rare damaging variant in GRIN2C in familial late-onset Alzheimer's disease by Elisa Rubino, Maria Italia, Elisa Giorgio, Silvia Boschi, Paola Dimartino, Tommaso Pippucci, Fausto Roveta, Clara Maria Cambria, Gabriella Elia, Andrea Marcinnò, Salvatore Gallone, Ekaterina Rogaeva, Flavia Antonucci, Alfredo Brusco, Fabrizio Gardoni, Innocenzo Rainero

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Machine Learning-Based Alzheimer’s Disease Stage Diagnosis Utilizing Blood Gene Expression and Clinical Data: A Comparative Investigation by Manash Sarma, Subarna Chatterjee

“…A deep learning (DL) classifier was used to identify the stages—cognitive normal (CN), mild cognitive impairment (MCI), and Alzheimer’s disease (AD)/dementia. DL, support vector machine (SVM), gradient boosting (GB), and random forest (RF) classifiers were used for the AD stage detection from gene expression profile data. …”
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Ecopsychosocial strategies for the self-exploration of professional family caregivers to manage the behavioural and psychological symptoms of Alzheimer patients in Iran: a qualitat... by Kambiz Bahaadinbeigy, Parastoo Amiri, Zahra Niazkhani, Habibollah Pirnejad

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A Novel Association of Polymorphism in the ITGA4 Gene Encoding the VLA-4 α4 Subunit with Increased Risk of Alzheimer’s Disease by Vladimira Durmanova, Zuzana Parnicka, Juraj Javor, Gabriel Minarik, Lubomir Vrazda, Barbora Vaseckova, Karin Gmitterova, Maria Kralova, Jan Pecenak, Peter Filipcik, Ivana Shawkatova

“…Alzheimer’s disease (AD) is the most prevalent cause of dementia in elderly people worldwide. …”
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Advancing Alzheimer’s disease risk prediction: development and validation of a machine learning-based preclinical screening model in a cross-sectional study by Yanfei Chen, Bing Wang, Yankai Shi, Wenhao Qi, Shihua Cao, Bingsheng Wang, Ruihan Xie, Jiani Yao, Xiajing Lou, Chaoqun Dong, Xiaohong Zhu, Danni He

“…Objectives Alzheimer’s disease (AD) poses a significant challenge for individuals aged 65 and older, being the most prevalent form of dementia. …”
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Elevation of ganglioside degradation pathway drives GM2 and GM3 within amyloid plaques in a transgenic mouse model of Alzheimer's disease by Wenxuan Wang, Sarah J. Myers, Nikita Ollen-Bittle, Shawn N. Whitehead

“…Alzheimer's disease (AD) is a progressive neurodegenerative disease that accounts for two-thirds of all dementia cases, and age is the strongest risk factor. …”
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Modern Imaging Methods in the Diagnosis of Neurodegenerative Diseases by Paulina Dorota Pietrukaniec, Bartosz Omasta, Katarzyna Kamińska-Omasta, Olga Krupa, Daria Rybak, Kuba Borys Romańczuk, Magdalena Agata Czerska, Szymon Przemysław Stolarczyk, Zofia Martyna Wójcik, Kinga Furtak

“… Neurodegenerative diseases, such as Alzheimer's, Parkinson's and other forms of dementia, represent a major global health challenge. …”
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Comparative the efficacy and safety of Gosuranemab, Semorinemab, Tilavonemab, and Zagotenemab in patients with Alzheimer’s disease: a systematic review and network meta-analysis of... by Wenting Cai, Wenting Cai, Hui Zhang, Hui Zhang, Yan Wu, Yan Wu, Yao Yao, Jinping Zhang

“…The efficacy indicators were change in the Mini Mental State Examination (MMSE), Clinical Dementia Rating Scale Sum of Boxes (CDR-SB), Alzheimer’s Disease Assessment Scale-Cognitive (ADAS-Cog), Alzheimer’s Disease Cooperative Study-Activities of Daily Living Scale (ADCS-ADL) from baseline until the time of efficacy observation. …”
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Isolation of Pleurotus florida derived acetylcholinesterase inhibitor for the treatment of cognitive dysfunction in mice by Kudrat Randhawa, Varinder Singh, Sanimardeep Kaur, Ravinder Kaur, Suresh Kumar, Richa Shri

“…It improved STZ induced dementia and neurodegeneration in mice by reducing brain acetylcholinesterase action and oxidative stress. …”
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Cognitive enhancing effect of an extract of Swertia chirata against memory impairment induced by aluminum chloride by Reena Deshmukh, Manisha Jaiswal, Anshita Shukla, Umesh Patil, Mukesh Sharma

“…Its anti-inflammatory and antioxidant properties may contribute to its potential in treating cognitive disorders, including dementia and Alzheimer's disease.…”
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