Predicting Cognitive Decline in Parkinson’s Disease with Mild Cognitive Impairment: A One-Year Observational Study by Pei-Hao Chen, Fang-Yu Cheng, Shih-Jung Cheng, Jin-Siang Shaw

“…Patients with PD-MCI had more physical disabilities, including scores of instrumental activities of daily living (IADL), Tinetti balance, and gait scores, and some Timed Up and Go components. Initial Clinical Dementia Rating—Sum of Boxes score was a better predictor of future cognitive decline than MMSE in PD-MCI. …”
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Comorbidities among Patients with Epilepsy Attending Imam Al-Sadiq General Hospital in Babylon Governorate, Iraq by Bilal Hadi Jawad, Khadija Shaban Hassan, Wahab Razzaq Ebdan

“…Among psychiatric comorbidities, 67.1% of them were suffered from anxiety and 61.9% with depression. 7.6% of patient were suffering from Dementia/ Alzheimer’s disease as cognitive comorbidities. …”
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Therapeutic potential of phytocompounds of Bacopa monnieri (L.) Wettst (literature review) by O.O. Nikitina, D.S. Tsyba

“…Numerous clinical trials show the effectiveness of the use of extracts in the treatment of anhedonia, depression, Alzheimer's disease, Parkinson's disease, dementia and hyperactivity. …”
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Brain-derived tau oligomer polymorphs: distinct aggregations, stability profiles, and biological activities by Filippa Lo Cascio, Suhyeorn Park, Urmi Sengupta, Nicha Puangmalai, Nemil Bhatt, Nikita Shchankin, Cynthia Jerez, Naomi Moreno, Alice Bittar, Rhea Xavier, Yingxin Zhao, Cankun Wang, Hongjun Fu, Qin Ma, Mauro Montalbano, Rakez Kayed

“…Abstract Aggregation of microtubule-associated tau protein is a distinct hallmark of several neurodegenerative disorders such as Alzheimer’s disease (AD), dementia with Lewy bodies (DLB), and progressive supranuclear palsy (PSP). …”
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Exploring the Effectiveness of Machine Learning and Deep Learning Techniques for EEG Signal Classification in Neurological Disorders by Souhaila Khalfallah, William Puech, Mehdi Tlija, Kais Bouallegue

“…Hence, our findings show impressive accuracy, with the random forest model achieving 99.85% accuracy in classifying autism vs. healthy subjects and 100% accuracy in distinguishing healthy individuals from those with dementia using Support Vector Machines (SVM). Moreover, deep learning models, including Convolutional Neural Networks (CNN) and ChronoNet, demonstrated accuracy rates ranging from 92.5% to 100%. …”
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Chlamydophila pneumoniae Infection and Its Role in Neurological Disorders by Carlo Contini, Silva Seraceni, Rosario Cultrera, Massimiliano Castellazzi, Enrico Granieri, Enrico Fainardi

“…The demonstration of C. pneumoniae by histopathological, molecular and culture techniques in the late-onset AD dementia has suggested a relationship between CNS infection with C. pneumoniae and the AD neuropathogenesis. …”
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The collaborative cross mouse for studying the effect of host genetic background on memory impairments due to obesity and diabetes by Avia Paz, Kareem Midlej, Osayd Zohud, Iqbal M. Lone, Fuad A. Iraqi

“…Previous studies have shown correlations between obesity, T2D, and neurodegenerative diseases, including dementia. It is imperative to further understand the relationship between obesity, T2D, and cognitive deficits. …”
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Electroacupuncture Mitigates Hippocampal Cognitive Impairments by Reducing BACE1 Deposition and Activating PKA in APP/PS1 Double Transgenic Mice by Yinshan Tang, Shujun Shao, Yu Guo, You Zhou, Jin Cao, Anping Xu, Jihong Wu, Zhigang Li, Dulian Xiang

“…Increased amyloid-β (Aβ) plaque deposition is thought to be the main cause of Alzheimer’s disease (AD). β-Site amyloid precursor protein cleaving enzyme 1 (BACE1) is the key protein involved in Aβ peptide generation. …”
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Wii-Fit for Improving Gait and Balance in an Assisted Living Facility: A Pilot Study by Kalpana P. Padala, Prasad R. Padala, Timothy R. Malloy, Jenenne A. Geske, Patricia M. Dubbert, Richard A. Dennis, Kimberly K. Garner, Melinda M. Bopp, William J. Burke, Dennis H. Sullivan

“…To determine the effects on balance and gait of a Wii-Fit program compared to a walking program in subjects with mild Alzheimer’s dementia (AD). Methods. A prospective randomized (1 : 1) pilot study with two intervention arms was conducted in an assisted living facility with twenty-two mild AD subjects. …”
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Improvement of Blood Plasmalogens and Clinical Symptoms in Parkinson’s Disease by Oral Administration of Ether Phospholipids: A Preliminary Report by Shiro Mawatari, Shinji Ohara, Yoshihide Taniwaki, Yoshio Tsuboi, Toru Maruyama, Takehiko Fujino

“…Nonmotor symptoms in PD include sleep problems, depression, and dementia, which are not adequately controlled with dopaminergic therapy. …”
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Water quality and neurodegenerative disease risk in the middle-aged and elderly population by Yujia Bao, Yongxuan Li, Yanqiu Zhou, Jingqi Zhou, Wei Mu, Xiaobei Deng, Chen Shen, Lefei Han, Jinjun Ran

“…We found water hardness in 0–120 mg/L elevated the incidence risks of Alzheimer’s disease and vascular dementia compared to that in 120–300 mg/L, with hazard ratios of 1.13 (1.01, 1.27) and 1.24 (1.05, 1.46), respectively. …”
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Long-Term Impact of Using Mobile Phones and Playing Computer Games on the Brain Structure and the Risk of Neurodegenerative Diseases: Large Population-Based Study by Yi Xiao, Sirui Zhang, Yuanzheng Ma, Shichan Wang, Chunyu Li, Yan Liang, Huifang Shang

“…MethodsWe used data from the UK Biobank, a longitudinal population-based cohort study, to analyze the impact of mobile phone use duration, weekly usage time, and playing computer games on the future brain structure and the future risk of various neurodegenerative diseases, including all-cause dementia (ACD), Alzheimer disease (AD), vascular dementia (VD), all-cause parkinsonism (ACP), and Parkinson disease (PD). …”
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Glymphatic system: a self-purification circulation in brain by Siying Chen, Siying Chen, Huijing Wang, Lini Zhang, Yingying Xi, Yiying Lu, Kailin Yu, Yujie Zhu, Izmailova Regina, Yong Bi, Fang Tong, Fang Tong

“…Damage to the glymphatic system will give rise to the development and progression of many brain diseases, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), chronic traumatic encephalopathy (CTE), and vascular dementia (VaD). …”
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Nonfluent/Agrammatic PPA with In-Vivo Cortical Amyloidosis and Pick’s Disease Pathology by Francesca Caso, Benno Gesierich, Maya Henry, Manu Sidhu, Amanda LaMarre, Miranda Babiak, Bruce L. Miller, Gil D. Rabinovici, Eric J. Huang, Giuseppe Magnani, Massimo Filippi, Giancarlo Comi, William W. Seeley, Maria Luisa Gorno-Tempini

“…The role of biomarkers in predicting pathological findings in the frontotemporal dementia (FTD) clinical spectrum disorders is still being explored. …”
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Molecular Mechanisms of Neurodegeneration Related to C9orf72 Hexanucleotide Repeat Expansion by Mirjana Babić Leko, Vera Župunski, Jason Kirincich, Dinko Smilović, Tibor Hortobágyi, Patrick R. Hof, Goran Šimić

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Research hotspots and trends in the antioxidant effects of acupuncture: A bibliometric analysis from 2003 to 2024 by Zhilin Huang, Song Li, YiHao Zhou, Anhong Dai, Yi Zhang, Meifang Liu, Mengqi Le, Jing Shi

“…Neurological disorders such as Parkinson's disease, vascular dementia, and stroke are major research areas in this field. …”
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Chitinase-3-like-1: a multifaceted player in neuroinflammation and degenerative pathologies with therapeutic implications by Pharaoh Fellow Mwale, Cheng-Ta Hsieh, Ting-Lin Yen, Jing-Shiun Jan, Rajeev Taliyan, Chih-Hao Yang, Wen-Bin Yang

“…Elevated CHI3L1 levels have been observed in neurological conditions such as traumatic brain injury (TBI), Alzheimer’s disease (AD), Parkinson’s disease (PD), Amyotrophic lateral sclerosis (ALS), Creutzfeldt-Jakob disease (CJD), multiple sclerosis (MS), Neuromyelitis optica (NMO), HIV-associated dementia (HAD), Cerebral ischemic stroke (CIS), and brain tumors. …”
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Targeting natural antioxidant polyphenols to protect neuroinflammation and neurodegenerative diseases: a comprehensive review by Maroua Jalouli, Md Ataur Rahman, Partha Biswas, Hasanur Rahman, Abdel Halim Harrath, In-Seon Lee, In-Seon Lee, Sojin Kang, Jinwon Choi, Moon Nyeo Park, Bonglee Kim, Bonglee Kim

“…These compounds possess diverse neuroprotective capabilities, including antioxidant, anti-inflammatory, and anti-amyloid properties, which contribute to mitigating the progression of neurodegenerative conditions such as Alzheimer’s Disease (AD), Parkinson’s Disease (PD), Dementia, Multiple Sclerosis (MS), Stroke, and Huntington’s Disease (HD). …”
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Clock-Drawing in Neurological Disorders by Gerald Dal Pan, Yaakov Stern, Mary Sano, Richard Mayeux

“…Patients with probable Alzheimer's disease and other dementias have gross impairments in clock-drawing. …”
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Clinical evidence of acupuncture for amnestic mild cognitive impairment: A systematic review and meta-analysis of randomized controlled trials by Guangyao Lin, Stella Lim Jin Yie, Shanshan Guo, Xuanling Li, Lianwei Xu

“…Background: People with amnestic mild cognitive impairment (aMCI) carry a substantial risk of developing dementia compared to non-amnestic MCI (naMCI). Several previous studies proved the remarkable effectiveness of acupuncture for MCI, but they didn't distinguish between aMCI and naMCI. …”
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