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19721
Correlation analysis of DLG5 and PD-L1 expression in triple-negative breast cancer
Published 2025-01-01“…In the absence of drug-targetable receptors, chemotherapy remains the sole systemic treatment alternative. Recent advancements in immunotherapy, particularly immune checkpoint inhibitors (ICIs) that target programmed death 1/programmed death ligand 1 (PD-1/PD-L1) and cytotoxic T lymphocyte associated antigen 4 (CTLA-4), have provided renewed optimism for the treatment of patients with TNBC. …”
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19722
Artemia sp. as a DNA vaccine vector for common carp Cyprinus carpio larvae
Published 2014-01-01“…Oral vaccine delivery through Artemia sp. is of one alternative way to overcome this problem. This experiment was carried out by analysis DNA vaccine expression encoding of glycoprotein gene (GP-11) on C. carpio. …”
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19723
Hybrid precoding and power allocation for mmWave NOMA systems based on time delay line arrays
Published 2022-06-01“…Specifically,the Dinkelbach method is applied in the outer layer to transform the fractional structure of the objective function in EE optimization into a subtractive structure, and the non-convex objective function is transformed into a convex function by using mathematical tools in the inner layer, and then an iterative algorithm based on alternating optimization (AO) is proposed for power allocation, and finally the solution of the initial problem is obtained by circular iteration in both inner and outer layers. …”
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19724
L’apport de la géomatique à la connaissance de la partie terminale de l’aqueduc du Gier à Lyon
Published 2023-12-01“…It is thus possible to suggest alternative routes based on road or plot boundaries. …”
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19725
Pemanfaatan Fuzzy Logic dan Hill Climbing untuk Optimasi Pengelolaan Tempat Pengolahan Sampah Reduce-Reuse-Recycle (TPS 3R) pada Dinas Lingkungan Hidup (DLH) DKI Jakarta
Published 2021-11-01“…The fuzzy logic is a method of weighting the criteria and Hill Cimbing is optimization method to determine the best of alternatives. The result contributes to DLH, which is to determine which TPS 3R is entitled to receive funding quickly and precisely. …”
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19726
Development of a real-time duplex PCR assay for simultaneously diagnosis of KHV and CEV in common carp and koi
Published 2023-07-01“…This real-time duplex PCR assay is a rapid, sensitive, and specific test for detecting KHV and CEV in carp fish, thus it can be considered a valid alternative assay in aquaculture clinical laboratories. …”
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19727
Pemilihan Susu Formula Anak Menggunakan Metode Analytic Hierarchy Process dan Simple Additive Weighting
Published 2023-04-01“…In this research, alternatives of milk brands can be added, changed and deleted so it’s dynamic. …”
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19728
Genetic diversity of Plasmodium falciparum reticulocyte binding protein homologue-5, which is a potential malaria vaccine candidate: baseline data from areas of varying malaria end...
Published 2025-01-01“…Abstract Background The limited efficacy of the two recently approved malaria vaccines, RTS,S/AS01 and R21/Matrix- M™, highlights the need for alternative vaccine candidate genes. Plasmodium falciparum Reticulocyte Binding Protein Homologue 5 (Pfrh5) is a promising malaria vaccine candidate, given its limited polymorphism, its essential role in parasite survival, a lack of immune selection pressure and higher efficacy against multiple parasites strains. …”
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19729
Productivity and quality of Moina sp. cultivated with various culture medium
Published 2021-10-01“… Cultivation of Moina sp is still constrained by its quality, productivity, and sustainability. The alternative solution is the use of cultivation media materials that have high nutritional content and easily available in large quantities to support the quality and productivity of Moina sp. and meet the needs of live feed. …”
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19730
Assainissement des eaux usées et risques socio – sanitaires et environnementaux en zones d’habitat planifié de Yaoundé (Cameroun)
Published 2003-05-01“…Parmi les propositions évoquées, les stations d'épuration par lagunage font partir des alternatives adaptées au traitement des eaux usées dans les quartiers à habitat structuré de Yaoundé : ce sont des systèmes souples et peu coûteux dans leur conception, leur réalisation et leur gestion. …”
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19731
Effects of autolytical fish protein hydrolysate on growth performance, survival rate, and hematological indices in farmed juvenile beluga, Huso huso
Published 2024-03-01“…Introduction: Aquaculture's rapid expansion has led to a high demand for fishmeal, a key protein source in aquafeed. To address this, alternatives like fish protein hydrolysates (FPHs) are being investigated. …”
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19732
Pro-inflammatory effects of inhaled Great Salt Lake dust particles
Published 2025-01-01“…Dust from the Salton Sea playa (SSD qPM2.5) also stimulated IL6 and IL8 mRNA expression and activated TRPV1 in vitro, but inhibition by TRPV1 and V3 antagonists was dose dependent. Alternatively, responses of THP-1 cells to the Great Salt Lake and Salton Sea dusts were partially mediated by TLR4 as opposed to TRPV1. …”
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19733
Effectiveness and safety of PD-1/L1 inhibitors as first-line therapy for patients with advanced or metastatic urothelial carcinoma who are ineligible for platinum-based chemotherap...
Published 2025-02-01“…Specifically, the combination of Enfortumab vedotin (EV) and pembrolizumab (Pembro) showed more effectiveness in treating patients compared to trials using the current standard treatment, suggesting that it could be a promising alternative treatment option.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42024510152.…”
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19734
Community benefits of mass distribution of three types of dual-active-ingredient long-lasting insecticidal nets against malaria prevalence in Tanzania: evidence from a 3-year clust...
Published 2025-01-01“…Dual active ingredient LLINs (dual-AI LLINs) have been rolled out as an alternative to pyrethroid (PY)-only LLINs to counteract this. …”
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19735
Potential impacts of marine fuel regulations on an Arctic stratocumulus case and its radiative response
Published 2025-01-01“…International regulations aiming to reduce SO<span class="inline-formula"><sub><i>x</i></sub></span> and particulate matter (PM) emissions mandate ships to burn fuels with reduced sulfur content or, alternatively, use wet scrubbing as an exhaust aftertreatment when using fuels with sulfur contents exceeding regulatory limits. …”
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19736
Comparison of Field and Virtual Vegetation Surveys Conducted Using Uncrewed Aircraft System (UAS) Imagery at Two Coastal Marsh Restoration Projects
Published 2025-01-01“…., 1–30 m) satellite imagery, manned airborne data, and traditional field surveys, yet it has not been thoroughly evaluated in a virtual capacity as an alternative to traditional field vegetation plot surveys. …”
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19737
Is intense exercise bad for your mind? Subjective, behavioral and physiological responses to a cognitive effort to failure
Published 2025-01-01“…Sequential Bayesian analysis for the main hypothesis (intense physical exercise reduces cognitive task performance) until it reached strong evidence in favor of the alternative hypothesis (BF10 > 6), or the null hypothesis (BF10 < 1/6) were conducted. …”
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19738
Hubungan Kadar LDL dan HDL Serum Ibu Hamil Aterm dengan Berat Lahir Bayi
Published 2014-09-01“…Uptake and usage of LDL by placenta to the fetus is an alternative mechanism to obtain fatty acids and essential amino acids. …”
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19739
Temperatura de superficie en el Valle del Río Neuquén Utilizando Imágenes LANDSAT
Published 2011-12-01“…Abstract Studies of surface and air temperature from LANDSAT need a great density of meteorological stations following the altitudinal variation and complexity of terrain. Alternative methods for the study of the spatial distribution are useful. …”
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19740
Percentage of primiparous water buffalo cows becoming pregnant in the first 90 days postpartum
Published 2023-11-01“…Therefore, this treatment could be an economical alternative to improve the reproductive efficiency of primiparous buffaloes calving in the short photoperiod season, managed with natural service, and having a good body condition score. …”
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