Exploring the impact and mechanisms of behavioral activation on sleep disorders in colorectal cancer: a randomized controlled trial by Anlong Li, Runze Huang, Han Ge, Dajie Liu, Shaochun Liu, Yingxue Jia, Jiaying Chai, Xinyi Zheng, Lijun Liu, Chen Gan, Jian Xu, Ling Cheng, Mingjun Zhang, Huaidong Cheng

“…Behavioral activation (BA), derived from cognitive behavioral therapy (CBT), offers a flexible, simple, and cost-effective alternative. BA highlights the importance of activation, a strategy that encourages active participation in positive, meaningful activities to boost positive experiences and reduce negative emotions, which may have potential benefits for individuals with sleep disorders. …”
Get full text

Revealing the heterogeneity of treatment resistance in less‐defined subtype diffuse large B cell lymphoma patients by integrating programmed cell death patterns and liquid biopsy by Wei Hua, Jie Liu, Yue Li, Hua Yin, Hao‐Rui Shen, Jia‐Zhu Wu, Yi‐Lin Kong, Bi‐Hui Pan, Jun‐Heng Liang, Li Wang, Jian‐Yong Li, Rui Gao, Jin‐Hua Liang, Wei Xu

“…Furthermore, our research indicated that patients with elevated PCDI scores could potentially show resistance to conventional chemotherapy treatments, yet they might derive an advantage from alternative inhibitors targeting specific signalling pathways. …”
Get full text

Prevalence, risk factors and associated ocular diseases of cerebral stroke: the population-based Beijing Eye Study by Jost B Jonas, Ya Xing Wang, Liang Xu, Wen Bin Wei

“…In multivariable regression analysis, a higher prevalence of previous stroke was correlated (Nagelkerke R2=0.20) with the systemic parameters of older age (p<0.001; OR 1.06; 95% CI 1.04 to 1.08), male gender (p<0.001; OR 0.54; 95% CI 0.40 to 0.74), lower quality of life score (p<0.001; OR 1.39; 95% CI 1.25 to 1.55), higher prevalence of arterial hypertension (p<0.001; OR 2.86; 95% CI 2.05 to 3.98), and cardiovascular disease (p<0.001; OR 1.8554; 95% CI 1.34 to 2.56), and with the ocular parameter of higher prevalence of diabetic retinopathy (p<0.001; OR 4.41; 95% CI 2.38 to 8.18) or alternatively, with higher stage of diabetic retinopathy (p<0.001; OR 1.64; 95% CI 1.26 to 2.14).Conclusions In this North Chinese population aged 50+ years, the prevalence of a previous stroke was 7.33% (95% CI 6.43% to 8.24%). …”
Get full text

Combining genotyping approaches improves resolution for association mapping: a case study in tropical maize under water stress conditions by Fernanda Carla Ferreira de Pontes, Ingrid Pinheiro Machado, Maria Valnice de Souza Silveira, Antônio Lucas Aguiar Lobo, Felipe Sabadin, Roberto Fritsche-Neto, Júlio César DoVale

“…These approaches may bias tropical maize analyses due to reliance on the temperate line B73 as the reference genome. An alternative is a simulated genome called “Mock,” adapted to the population using bioinformatics. …”
Get full text

Comparison of 1D and 3D volume measurement techniques in NF2-associated vestibular schwannoma monitoring by Isabel Gugel, Nuran Aboutaha, Bianca Pfluegler, Ulrike Ernemann, Martin Ulrich Schuhmann, Marcos Tatagiba, Florian Grimm

“…Compared to the SVA, the MLD3 and especially the OA are a time-saving alternative for monitoring the tumor volume of NF2-associated VS. …”
Get full text

Urinary human papillomavirus DNA as an indicator of gynaecological infection in young women in Schistosoma and HIV endemic South Africa by P. Pillay, H. N. Galappaththi-Arachchige, M. Taylor, B. Roald, B. Roald, E. F. Kjetland, E. F. Kjetland

“…There was no statistical association between urinary schistosomiasis and HPV or with any atypia.ConclusionUrine has the potential of being optimized as an alternative and possibly more acceptable sample for HPV detection among young adolescent populations at risk in comparison to CVL samples. …”
Get full text

Risk Values of Weight and Body Mass Index for Chest Wall Thickness in Patients Requiring Needle Thoracostomy Decompression by Chia-Hung Hsu, Tzu-Yin Lin, Ju-Chi Ou, Jiann Ruey Ong, Hon-Ping Ma

“…A catheter of suitable length may not be available immediately or the muscle structure of the chest wall may be modified in pneumothorax. Furthermore, alternative sites for needle thoracostomy and reference values of chest wall thickness (CWT) should be explored and warranted. …”
Get full text

Merck Open Global Health Library in vitro screening against Schistosoma mansoni identified two new substances with antischistosomal activities for further development by Monique Evelyn Ueberall, Martina Berchthold, Cécile Häberli, Sven Lindemann, Thomas Spangenberg, Jennifer Keiser, Christoph G. Grevelding

“…Methods To identify potential alternative drugs for repurposing, the Open Global Health Library (OGHL) was screened in vitro, using two different screening workflows at two institutions, against adult S. mansoni couples and newly transformed schistosomula. …”
Get full text

Pembangunan Aplikasi Virtual Reality Tur Perumahan Pada Balimbingan Permai Regency (PT. Karya Propertindo Utama) by Komang Candra Brata, Reinhard Jonathan Silalahi, Adam Hendra Brata

“…The main feature of the proposed app is to manage and display all types and details of the house unit catalog in Virtual Reality so that it can be used as an alternative solution for prospective buyers who cannot conduct direct site surveys due to limited time and distance issue. …”
Get full text

Perioperative outcomes of video-assisted versus right anterior thoracotomy mitral valve replacement: an observational study by Gehad Awad, Fetoh Alaaeldin Fetoh, Noureldin Noaman Gwely, Usama Hamza, Sameh Amer, Yomna Mohammed Yehya, Amr Abdellateef

“…Abstract Background Minimally invasive mitral valve surgery has been introduced as a safe alternative to full sternotomy through smaller chest wall incisions to reduce the potential sternal complications in addition to the favorable aesthetic effect. …”
Get full text

Acceptance, Safety, and Effect Sizes in Online Dialectical Behavior Therapy for Borderline Personality Disorder: Interventional Pilot Study by Ruben Vonderlin, Tali Boritz, Carola Claus, Büsra Senyüz, Saskia Mahalingam, Rachel Tennenhouse, Stefanie Lis, Christian Schmahl, Jürgen Margraf, Tobias Teismann, Nikolaus Kleindienst, Shelley McMain, Martin Bohus

“…Overall, telehealth DBT might offer a potentially effective alternative treatment option, enhancing treatment accessibility. …”
Get full text

Iron(III)–Quercetin Complex: In Vivo Acute Toxicity and Biodistribution of Novel MRI Agent by Innuan P, Kongkarnka S, Thongtharb A, Kantapan J, Dechsupa N

“…It has demonstrated therapeutic benefits in reducing inflammation in an intracerebral hemorrhage (ICH) mouse model and offers a safer alternative to gadolinium-based agents by avoiding cytotoxicity and genotoxicity. …”
Get full text

Dynamique forestière et pression urbaine dans le Parc national du Banco (Abidjan, Côte d’Ivoire) by Nakouma Sako, Gérard Beltrando, Koffi Lazare Atta, Hyppolite Dibi N’da, Télesphore Brou

“…The development of the park through ecotourism, the development of alternative activities toward poachers and illegal loggers are among the many strategies implemented to save this threatened ecosystem. …”
Get full text

Conditional diffusion-generated super-resolution for myocardial perfusion MRI by Changyu Sun, Changyu Sun, Neha Goyal, Yu Wang, Darla L. Tharp, Senthil Kumar, Talissa A. Altes

“…This approach has shown the potentials to accelerate myocardial perfusion MRI while enhancing slice coverage and temporal resolution, offering a promising alternative to existing methods.…”
Get full text

Comparison of the Fixation Effects of Six Composite Fixatives on Retinal Tissue of Golden Hamsters by WU Haifeng, ZHOU Xiaojiang, LI Chenjiang, LI Huaiyin, GAO Ming

“…Therefore, Davidson's fixative is recommended as the optimal fixative for golden hamster retinal tissue, with 4% paraformaldehyde, Bouin's and Carnoy fixatives as alternative options.…”
Get full text

Brain connectivity for constructing new face representations in typical adults versus a prosopagnosic patient by Ela I. Olivares, Jorge F. Bosch-Bayard, Ana S. Urraca, Alba Jiménez-Bascuñán, Rolando J. Biscay, Jaime Iglesias

“…Nevertheless, in case of face agnosia after right posterior damage, relying preferentially on internal features and left hemisphere specialized subroutines might be an alternative for cognitive training.…”
Get full text

Efficacy and safety of transanal endoscopic microsurgery for early rectal cancer: a meta-analysis by Chunqiang Wang, Tianye Huang, Xuebing Wang

“…BackgroundThe gold standard for the treatment of rectal cancer is radical surgery with total mesorectal excision (TME). As one of the alternatives to radical surgery, local resection has been proposed for the treatment of early rectal cancer. …”
Get full text

Human Factors Studies to Assess the Usability of the Faricimab Prefilled Syringe by Barakat MR, Kwong Jr HM, Marcon G, O'Leary OE, Paris LP, Schneider P, Tang Y, Graff JM

“…The faricimab 6 mg PFS may therefore offer a more convenient, safe-handling alternative to vial administration.Keywords: intravitreal injection, medical device, retina specialist, human factors validation study, anti-vascular endothelial growth factor therapy…”
Get full text

Low-cost phone-based LiDAR scanning technology provides sub-centimeter accuracy when measuring the main dimensions of motor-manual tree felling cuts by Stelian Alexandru Borz, Andrea Rosario Proto

“…Motor-manual tree felling in one of the most important technical alternatives in timber harvesting. Commonly, it requires a sequence of cuts and may cause higher volume losses compared to mechanized tree felling. …”
Get full text

Genetic variants associated with sepsis-associated acute kidney injury. by Nicholas J Douville, Lisa Bastarache, Emily Bertucci-Richter, Snehal Patil, Elizabeth S Jewell, Robert E Freundlich, Miklos D Kertai, Milo C Engoren

“…We failed to replicate associations from multiple prior studies which may result from differences in how the phenotype was defined or, alternatively, limited genetic contribution and low heritability.…”
Get full text