<i>Sambucus nigra</i>-Lyophilized Fruit Extract Attenuated Acute Redox–Homeostatic Imbalance via Mutagenic and Oxidative Stress Modulation in Mice Model on Gentamicin-Induced Nephr... by Kamelia Petkova-Parlapanska, Ivaylo Stefanov, Julian Ananiev, Tsvetelin Georgiev, Petya Hadzhibozheva, Veselina Petrova-Tacheva, Nikolay Kaloyanov, Ekaterina Georgieva, Galina Nikolova, Yanka Karamalakova

“…<b>Conclusions:</b> Histological evaluation confirmed that <i>S. nigra</i> (120 mg kg⁻¹) attenuated renal dysfunction and structural damage by modulating oxidative stress and acute inflammation and could be used as an anti-fibrotic alternative in GM nephrotoxicity.…”
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Parallel randomised trial testing community fibrosis assessment for suspected non-alcoholic fatty liver disease: outcomes from LOCATE-NAFLD by Sanjeewa Kularatna, James O'Beirne, Adrian Barnett, Patricia C Valery, Elizabeth Powell, Ingrid J Hickman, Ruth Tulleners, David Brain, Katherine Stuart, Carolyn McIvor, Elen Witness, Melanie Aikebuse

“…The LOCal Assessment and Triage Evaluation of Non-Alcoholic Fatty Liver Disease (LOCATE-NAFLD) trialled a community-based fibrosis assessment service using FibroScan to reduce the time to diagnosis of high-risk NAFLD and improve patient outcomes.Methods We conducted a 1:1 parallel randomised trial to compare two alternative models of care for NAFLD diagnosis and assessment. …”
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A blended learning approach for capacity strengthening to improve the quality of integrated HIV, TB, and malaria services during antenatal and postnatal care in LMICs: a feasibilit... by Alice Norah Ladur, Uzochukwu Egere, Marion Ravit, Florence Mgawadere, Christopher Murray, Sarah Ann White, Mohammed Hauwa, Rael Mutai, Lucy Nyaga, Shikuku Duncan, Issak Bashir, Olubunmi Olufunmilola Ayinde, Rukia Bakar, Leonard Katalambula, Carlo Federici, Aleksandra Torbica, Nicholas Furtado, Elizabeth Adjoa Kumah, Charles Ameh

“…The Covid-19 pandemic increased the urgency to identify alternatives to traditional face-to-face (f2f) education approach. …”
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Cyclophilin–CD147 interaction enables SARS-CoV-2 infection of human monocytes and their activation via Toll-like receptors 7 and 8 by Gabor Tajti, Laura Gebetsberger, Gregor Pamlitschka, Katharina Aigner-Radakovics, Judith Leitner, Peter Steinberger, Hannes Stockinger, Anna Ohradanova-Repic

“…Firstly, SARS-CoV-2 infects monocytes in a process independent of the S protein and the prime SARS-CoV-2 receptor angiotensin-converting enzyme 2. Instead, the alternative SARS-CoV-2 receptor CD147, which is highly expressed on monocytes, recognizes its well-known interaction partners cyclophilins A and B that are incorporated into SARS-CoV-2 virions. …”
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O multiculturalismo e as divergências teóricas no debate multicultural by Willian Martini

“…At last, we will present Peter McLaren’s critical multiculturalism as a viable theoretical alternative to overcome the problem. My intention is to explain the link between the type of multiculturalism defended by one position and the problems or issues to which it is linked.…”
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Effectiveness of an online food shopping intervention to reduce salt purchases among individuals with hypertension – findings of the SaltSwitch Online Grocery Shopping (OGS) random... by Jason HY Wu, Damian Maganja, Liping Huang, Kathy Trieu, Fraser Taylor, Eden M. Barrett, Clare Arnott, Xiaoqi Feng, Aletta E. Schutte, Gian Luca Di Tanna, Cliona Ni Mhurchu, Adrian J. Cameron, Mark D. Huffman, Bruce Neal

“…The SaltSwitch extension modified a retailer’s online shopping interface to suggest similar but lower sodium alternative products to those initially selected. The primary outcome was the difference in mean sodium density (mg sodium per 1000 kcal of energy) of packaged food purchases between the intervention and control groups. …”
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Mechanisms of L-citrulline on phosphodiesterase 5 in erectile dysfunction intervention by Abdulhakeem Olarewaju Sulyman, Olawale Moshood Aliyu, Emmanuel Oladipo Ajani, Yusuf Folohunsho Abdulkareem, Isaac Ade Afe, Fathia Oluwakemi Abdulyakeen, Halimat Yusuf Lukman, Saheed Sabiu, Karishma Singh, Kuben Naidoo

“…Plant-derived products, though less explored, offer potential alternatives. This study evaluated the inhibitory effect of citrulline from Citrullus lanatus on PDE5 activity using experimental and computational methods to explore its therapeutic potential. …”
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Development and evaluation of a CRISPR/Cas12a-based diagnostic test for rapid detection and genotyping of HR-HPV in clinical specimens by Lijuan Yin, Ziqian Zhao, Chunhua Wang, Caihong Zhou, Xiuzhen Wu, Baoxue Gao, Liangyuan Wang, Shuli Man, Xinkuan Cheng, Qiankun Wu, Siqi Hu, Hongxia Fan, Long Ma, Hui Xing, Liang Shen

“…Based on these findings, our CRISPR/Cas-based HR-HPV detection platform holds promise as a novel clinical detection tool, offering a visually intuitive and expedited alternative to existing HPV infection diagnostics and providing fresh perspectives for clinical cervical cancer screening.IMPORTANCEThis study developed a novel high-risk human papillomavirus (HR-HPV) detection platform based on CRISPR/Cas12a technology. …”
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Parameter influences of FTO/ZnO/Cu₂O photodetectors fabricated by electrodeposition and spray pyrolysis techniques by Muthiah N. Najah, Frida A. Rahmania, Integralita Cahyanti, Maulida Hesnaty, Siti Hajar Alias, Djoko Hartanto, Wahyu Prasetyo Utomo, Retno Sari, Hadi Nur

“…This study investigates fabrication of transparent conductive glass using fluorine-doped tin oxide (FTO) as a more affordable alternative to indium tin oxide (ITO) in photovoltaic applications. …”
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Comparable outcomes after busulfan- or treosulfan-based conditioning for allo-HSCT in children with ALL: results of FORUM by Krzysztof Kalwak, Laura M. Moser, Ulrike Pötschger, Peter Bader, Katharina Kleinschmidt, Roland Meisel, Jean-Hugues Dalle, Akif Yesilipek, Adriana Balduzzi, Gergely Krivan, Evgenios Goussetis, Raquel Staciuk, Petr Sedlacek, Herbert Pichler, Peter Svec, Melissa Gabriel, Tayfun Güngör, Ernest Bilic, Jochen Buechner, Marleen Renard, Kim Vettenranta, Marianne Ifversen, Cristina Diaz-de-Heredia, Jerry Stein, Jacek Toporski, Marc Bierings, Christina Peters, Marc Ansari, Franco Locatelli

“…In conclusion, BU/THIO/FLU or TREO/THIO/FLU regimens can be an alternative to TBI for patients with ALL aged >4 years with contraindications or lack of access to TBI. …”
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An aquaria set‐up for long‐term, multiple‐stressor research in marine organisms by Cristina Gutiérrez‐Zárate, Alfredo Veiga, Andrea Gori, Fabián Gerpe, Leo Domínguez, Alberto Rodríguez, Noelia Arias, Marta Álvarez, Rubén Acerbi, Lucía Vázquez, Juancho Movilla, Marta M. Varela, Rodrigo Alba‐Salgueiro, Joaquín Valencia‐Vila, Covadonga Orejas

“…The set‐up performed well over extensive periods while providing a customisable controller as a cost‐effective alternative. The versatility of the system, allowing to work with different species, environments and scenarios makes it valuable for aquaria experiments where interactions of multiple environmental factors need to be tested.…”
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Prediction of embryo euploidy and pregnancy outcome by blastocyst morphology and development speed for women receiving single embryo transfer by Kexin Dong, Chunyan Wu, Xuerong Hou, Yanhong Zeng, Lu Luo

“…Transfer of euploid blastocysts with high-grade morphology resulted in a greater ongoing pregnancy rate than transfer of non-high-grade euploid blastocysts (60.7% vs. 43.2%, P = 0.049). Alternatively, D6 development speed was an independent risk factor for early pregnancy loss after euploid blastocyst transfer. …”
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Prognostic Value of Postpercutaneous Coronary Intervention Murray-Law-Based Quantitative Flow Ratio by Daixin Ding, PhD, Jinlong Zhang, MD, PhD, Peng Wu, PhD, Zhiqing Wang, MD, PhD, Huiping Shi, MSc, Wei Yu, PhD, Xinyang Hu, MD, PhD, Jeehoon Kang, MD, Joo-Yong Hahn, MD, Chang-Wook Nam, MD, Joon-Hyung Doh, MD, Bong-Ki Lee, MD, Weon Kim, MD, Jinyu Huang, MD, Fan Jiang, MD, Hao Zhou, MD, Peng Chen, MD, Lijiang Tang, MD, Wenbing Jiang, MD, Xiaomin Chen, MD, Wenming He, MD, Sung Gyun Ahn, MD, Myeong-Ho Yoon, MD, Ung Kim, MD, You-Jeong Ki, MD, Eun-Seok Shin, MD, Seung-Jea Tahk, MD, Jun Pu, MD, William Wijns, MD, PhD, Jian’an Wang, MD, PhD, Bon-Kwon Koo, MD, PhD, Shengxian Tu, PhD

“…Murray law-based quantitative flow ratio (μQFR) may represent a promising alternative, as it can quickly compute FFR from a single angiographic view. …”
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Sustainability index analysis of the black soldier fly (Hermetia illucens) cultivation from food waste substrate by A.D. Santoso, T. Handayani, R.A. Nugroho, A.I. Yanuar, N. Nadirah, E.S. Rohaeni, E. Widjaja, M.A.M. Oktaufik, U. Ayuningtyas, Y.P. Erlambang, R. Herdioso, M.N. Rofiq, R. Hutapea, A.L. Sihombing, B. Rustianto, I.M.A.D Susila, D. Irawan, D. Iskandar, S. Indrijarso, G.D. Widiarta

“…Sustainability status and leverage attributes were analyzed by Monte Carlo analysis, and alternating least-squares algorithm.FINDINGS: Sustainability index for larvae of black soldier fly production was 89.69 percent. …”
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Challenges and Strategies Adopted for Remote Teaching of Biochemistry During the COVID-19 Pandemic: Protocol for a Scoping Review by Tatiane Iembo, Helena Landim Gonçalves Cristóvão, Emerson Roberto dos Santos, André Bavaresco Gonçalves Cristóvão, Nathália Bavaresco Gonçalves Cristóvão, Cíntia Canato Martins, Natália Almeida de Arnaldo Silva Rodrigues Castro, Fernando Nestor Facio Júnior, Antônio Hélio Oliani, Alba Regina de Abreu Lima, Vânia Maria Sabadoto Brienze, Doroteia Rossi Silva Souza, Júlio César André

“…It encompasses a variety of pedagogical approaches, including online teaching tools, interactive methods, and alternatives to practical laboratory classes. The search spans databases such as MEDLINE, the Cochrane Database of Systematic Reviews, and Joanna Briggs Institute (JBI) Evidence Synthesis, with a focus on identifying systematic or scoping reviews; however, none were identified in the preliminary search. …”
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Chemical Characterization and Antimicrobial Activity of Essential Oils and Nanoemulsions of <i>Eugenia uniflora</i> and <i>Psidium guajava</i> by Rebeca Dias dos Santos, Breno Noronha Matos, Daniel Oliveira Freire, Franklyn Santos da Silva, Bruno Alcântara do Prado, Karolina Oliveira Gomes, Marta Oliveira de Araújo, Carla Azevedo Bilac, Letícia Fernandes Silva Rodrigues, Izabel Cristina Rodrigues da Silva, Lívia Cristina Lira de Sá Barreto, Claudio Augusto Gomes da Camara, Marcilio Martins de Moraes, Guilherme Martins Gelfuso, Daniela Castilho Orsi

“…The time–growth inhibition assay also suggests the effectiveness of the NE against the tested pathogens <i>S. aureus</i> and <i>E. coli</i>, highlighting its potential as a novel alternative therapeutic agent.…”
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Sewage sludge-based organomineral fertilizer: A pathway to enhanced soil fertility and chickpea production by Athos Rodrigues Soares Viana, Rodinei Facco Pegoraro, Regynaldo Arruda Sampaio, Luiz Arnaldo Fernandes, Leidivan Almeida Frazão, Cândido Alves da Costa, Verônica Aparecida Santos Ferreira Soares

“… • Stabilized sludge in powder or granulated form can serve as an alternative fertilizer source. • Organomineral and mineral NPK fertilizers are equivalent in chickpea production. …”
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A new distal radius fracture classification depending on the specific fragments through machine learning clustering method by Yuling Gao, Yanrui Zhao, Yang Liu, Shan Lei, Hanzhou Wang, Yuerong Lizhu, Tianchao Lu, Zhexian Cheng, Dong Wang, Binzhi Zhao, Ziyi Li, Junlin Zhou

“…The volar plate fixation is an effective treatment for the intra-articular distal radius fractures, while combined plate fixation can be considered as an alternative treatment for dorsal side comminuted fractures. …”
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Echo- and B-Type Natriuretic Peptide-Guided Follow-Up versus Symptom-Guided Follow-Up: Comparison of the Outcome in Ambulatory Heart Failure Patients by Gani Bajraktari, Nicola Riccardo Pugliese, Andreina D’Agostino, Gian Marco Rosa, Pranvera Ibrahimi, Luan Perçuku, Mario Miccoli, Gian Giacomo Galeotti, Iacopo Fabiani, Roberto Pedrinelli, Michael Henein, Frank L. Dini

“…Combination of echo- and B-type natriuretic peptide (BNP) may be an alternative approach in guiding ambulatory HF management. …”
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Evaluation of Two Different Solvents for Azolla pinnata Extracts on Chemical Compositions and Larvicidal Activity against Aedes albopictus (Diptera: Culicidae) by Rajiv Ravi, Nor Shaida Husna Zulkrnin, Nurul Nadiah Rozhan, Nik Raihan Nik Yusoff, Mohd Sukhairi Mat Rasat, Muhammad Iqbal Ahmad, Zulhazman Hamzah, Intan H. Ishak, Mohamad Faiz Mohd Amin

“…Limited success for Aedes control program has impelled the necessities for new insecticide search. Hence, alternative plant compounds may be competent to overcome the pesticide resistance problem and to lead a chemical-free environment. …”
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