Intensity of Oestrus Signalling Is the Most Relevant Indicator for Animal Well-Being in High-Producing Dairy Cows by Emanuel Garcia, Jan Hultgren, Pontus Fällman, Johanna Geust, Bo Algers, George Stilwell, Stefan Gunnarsson, Heriberto Rodriguez-Martinez

“…Full signalling of oestrous behaviour is vital for proper timing of AI and good reproductive performance, currently jeopardized by shorter observations of oestrus behaviour. Alternative indicators including progesterone (P4) recordings on-farm are tested. …”
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Fructosamine and Hemoglobin A1c Correlations in HIV-Infected Adults in Routine Clinical Care: Impact of Anemia and Albumin Levels by Luisa Duran, Carla Rodriguez, Dan Drozd, Robin M. Nance, J. A. Chris Delaney, Greer Burkholder, Michael J. Mugavero, James H. Willig, Amy H. Warriner, Paul K. Crane, Ben E. Atkinson, Robert D. Harrington, Shireesha Dhanireddy, Michael S. Saag, Mari M. Kitahata, Heidi M. Crane

“…Fructosamine is an alternative method to hemoglobin A1c (HbA1c) for determining average glycemia. …”
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Sustainable leachate treatment by integrating electrolysis with palm-shell activated carbon contactor for environmental protection by Amimul Ahsan, Muhamad Jasarudin Bin Mat Ali, Md. Redowan Rashid, Mozaher Ul Kabir, Md. Shafiquzzaman, Monzur Imteaz, Syazwani Idrus, Mohammad Aljaradin, Mohammad T. Alresheedi

“…Future study should focus on implementing rigorous laboratory protocols, ensuring accurate dilution factors, refraining from reusing activated carbon, maintaining continuous monitoring throughout treatment operations, and investigating alternative treatment approaches. This study makes a valuable contribution to the ongoing endeavors aimed at tackling the environmental issues related to the treatment of landfill leachate.…”
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Evaluation of the Capability of Horizontal ATR-FTMIR and UV-Visible Spectroscopy in the Discrimination of Virgin Olive Oils from the Moroccan Region of Beni Mellal-Khenifra by Aimen El Orche, Mustapha Bouatia, Siham Yanisse, Houda Labjar, Mouad Mouhsin, Mohamed Bouha, Mustapha Oubenali, Mohamed Mbarki

“…Such developed methods can be proposed as alternative and complementary methods to authenticate the geographical origin of virgin olive oil.…”
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Working experiences of remote interpreters in health care settings—insights from Austria and Germany by Sophie Klomfar, Sophie Klomfar, Anna Teufel, Gernot Gerger, Maria Kletečka-Pulker, Maria Kletečka-Pulker, Klara Doppler, Klara Doppler, Magdalena Eitenberger, Magdalena Eitenberger, Sabine Völkl-Kernstock, Sabine Völkl-Kernstock

“…VRI is an efficient alternative to in-person interpreting, with challenges that can be mitigated. …”
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Design and Characteristics of a Single-Story Building Model Incorporating Waste by Mohamed Darwish, Mohamed Elnakeb, Marina Moawad, Marwan Mohamed Shawki, Ehab Abdelhamid, Donia Eldwib, Mohamed Nagib Abouzeid, Maram Saudy, Safwan Khedr, Khaled Nassar

“…Analysis of both the short-term and long-term costs and carbon emissions was performed by acquiring the carbon emissions per unit of material from literature and multiplying it by the quantities of the materials used within the different building alternatives. That study showed that the roofs made of Structural Insulated Panels (SIPs) using Wood-Plastic Composite (WPC) facings when used with hollow-block cement block walls have shown enduring cost efficiency and improved thermal insulation, leading to diminished energy usage, life-cycle expenses, and carbon emissions. …”
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Rational engineering of Escherichia coli strain for stable and enhanced biosynthesis of pinene by Muhammad Hammad Hussain, Lu Han, Yanlong Wei, Muhammad Javid, Kamran Ashraf, Maria Martuscelli, Waleed Aldahmash, Meijin Guo, Ali Mohsin, Zhanxia Li

“…Monoterpene α-pinene exhibits significant potential as an alternative fuel, widely recognized for its affordability and eco-friendly nature. …”
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Human blood cell transcriptomics unveils dynamic systemic immune modulation along colorectal cancer progression by Pedro J Romero, Mauro Delorenzi, Amaia Martínez-Usatorre, Laura Ciarloni, Noushin Hadadi, Eric Durandau, Sylvain Monnier-Benoit, Paolo Angelino, Victoria Wosika, Alessandra Jordano Conforte, Sara S Fonseca Costa, Hector Fabio Satizabal, Jérémie Despraz, Andres Perez-Uribe, Stephan Morgenthaler, Brian Hashemi, Sahar Hosseinian-Ehrensberger

“…Here we propose the host immune response to the onset of cancer as an alternative approach for early detection of CRC.Methods We perform whole transcriptome analysis of peripheral blood mononuclear cells (PBMCs) isolated from individuals with CRC, precancerous lesions or negative colonoscopy in two independent cohorts using next-generation sequencing.Results We discover and validate novel early CRC RNA biomarkers. …”
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Modification of hempseed protein isolate using a novel two-stage method applying high-pressure homogenization coupled with high-intensity ultrasound by Ruyu Zhang, Wangang Zhang, Xuan Dong, Meng Wai Woo, Siew Young Quek

“…Hempseed protein isolate (HPI), a novel plant protein, possesses advantages as an alternative food protein from a nutritional and sustainable perspective. …”
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Exploring the Photocatalytic Efficiency of Gold Nanoparticles Deposited on Ni-Al-Zr-Layered Double Hydroxides for Selective Glucose Oxidation by Nihel Dib, Frédéric Sauvage, Lucie Quéhon, Khadidja Khaldi, Sumeya Bedrane, José Juan Calvino, Redouane Bachir, Ginesa Blanco, Gwladys Pourceau

“…Among the most promising alternatives, sugars derived from biomass are emerging as a cornerstone in advancing an environmentally sustainable economy. …”
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Achilles Tendon Rupture In Recreational Athletes - Hobby-Ending Incident or Easily Treatable Injury? Current Insight Into Risk Factors, Treatment Options and Recovery Strategies by Jakub Kędzia, Joanna Duda, Kinga Racisz, Paweł Racisz, Alicja Obcowska, Aleksandra Walendzik, Łukasz Sencerek

“…The recovery period typically lasts around six months, with rehabilitation being a key component. Other alternative methods and their benefits are being explored. …”
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Clinical efficacy and safety of proton radiotherapy for ocular conjunctival malignancies: a systematic review and meta-analysis by Tingwei Zheng, Tingwei Zheng, Dandan Wang, Yuxin Miao, Yuxin Miao, Meng Dong, Qin Liu, Qin Liu, Qiuning Zhang, Huiling Bai, Huiling Bai, Hongtao Luo, Meixuan Li

“…The GRADE assessment yielded a low certainty of evidence.ConclusionsProton therapy offers a viable alternative treatment for patients with conjunctival malignancies, with acceptable treatment-related toxicity rates.…”
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Liquid-based cytological diagnosis of pancreatic neuroendocrine tumors using hyperspectral imaging and deep learning by Taojing Ran, Wei Huang, Xianzheng Qin, Xingran Xie, Yingjiao Deng, Yundi Pan, Yao Zhang, Ling Zhang, Lili Gao, Minmin Zhang, Dong Wang, Yan Wang, Qingli Li, Chunhua Zhou, Duowu Zou

“…With further validation, this innovative technique can be utilized as an alternative to traditional cytological diagnosis for higher efficiency, thus reducing the workload of daily clinical practice.…”
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Advancements in Nanotechnology for Enhanced Food Safety and Hygiene: Pathogen Detection, Smart Packaging, and Preservation Applications by Farhang Hameed Awlqadr, Ammar B. Altemimi, Qausar Hamed AlKaisy, Syamand Ahmed Qadir, Aryan Mahmood Faraj, Tablo Azad H.Slih, Rawaa H. Tlay, Tarek Gamal Mohamed Abd El-Maksoud, Franscesco Cacciola

“…The emergence of biodegradable nanocomposites and edible films offers eco-friendly packaging alternatives, addressing environmental concerns while maintaining food integrity. …”
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Evaluation of 2,3-butanediol derived from whey fermentation as an effective bio-based monomer for waterborne polyurethane dispersions by Lorena Germán-Ayuso, Rubén Cobos, Leire Lorenzo, Francisca Río, Soraya Prieto-Fernández, Tomás Roncal, José M. Cuevas

“…The combination of 100% bio-based polyether polyols with partially renewable L-lysine ethyl ester diisocyanate and whey-derived 2,3-BDO as a chain extender generated totally stable, low-particle-size water dispersions of amorphous polymers characterised by similar structure and molecular weight compared to those of alternative petroleum-based PUDs. These results open up the possibility of incorporating fermentation-derived 2,3-BDO as a totally renewable component in bio-based PUDs as potential sustainable resinous systems for further formulation of water-based coatings or adhesives.…”
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Impact of stream-groundwater interaction on stream water source composition: A case study of the Dosit River by Lanfang DING, Zhiyuan ZHANG, Xiaowei JIANG, Xusheng WANG, Li WAN

“…The alternation of gaining and losing reaches is a common manifestation of stream-groundwater exchange, and studies on the stream water source composition where source means the location of gaining reaches have become one of the frontiers in stream water quality research. …”
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Efficacy and safety of avacopan in antineutrophil cytoplasmic autoantibody-associated vasculitis: a retrospective cohort study in Japan by Genri Tagami, Makoto Yamaguchi, Hirokazu Sugiyama, Hiroshi Kinashi, Kentaro Imai, Keisuke Kamiya, Takayuki Katsuno, Takahiro Imaizumi, Shogo Banno, Yasuhiko Ito, Takuji Ishimoto

“…Abstract Background Avacopan, an oral C5a receptor antagonist, demonstrated efficacy as an alternative to glucocorticoid therapy in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in the phase 3 ADVOCATE trial. …”
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Pivotal role of Helicobacter pylori virulence genes in pathogenicity and vaccine development by Ayman Elbehiry, Eman Marzouk, Adil Abalkhail, Wael Sindi, Yasir Alzahrani, Salem Alhifani, Turki Alshehri, Nuha Abdulaziz Anajirih, Turki ALMutairi, Ahmad Alsaedi, Feras Alzaben, Abdullah Alqrni, Abdelmaged Draz, Abdulaziz M. Almuzaini, Sahar N. Aljarallah, Abdulrahman Almujaidel, Akram Abu-Okail

“…Consequently, the development of vaccines targeting virulence factors may present a viable alternative for the treatment and prevention of H. pylori infections. …”
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Evaluation of the efficacy of a novel lumbar exoskeleton with multiple interventions for patients with lumbar disc herniation: a multicenter randomized controlled trial of non-infe... by Xiaonan Huang, Xiaonan Huang, Lele Huang, Lele Huang, Lei Shi, Lifan Xu, Lifan Xu, Chengbing Cao, Heng Wu, Min Cao, Can Lv, Ping Shi, Guohui Zhang, Fanfu Fang

“…However, there was no significant difference in the overall efficacy rate between the two groups (P = 0.748).ConclusionThe novel lumbar exoskeleton device demonstrates comparable efficacy and safety to traditional traction therapy combined with rehabilitation, offering a promising alternative for the conservative treatment of LDH.…”
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Combination gemcitabine and PD-L1xCD3 bispecific T cell engager (BiTE) enhances T lymphocyte cytotoxicity against cholangiocarcinoma cells by Methi Wathikthinnakon, Piriya Luangwattananun, Nunghathai Sawasdee, Chutipa Chiawpanit, Vannajan Sanghiran Lee, Piyarat Nimmanpipug, Yingmanee Tragoolpua, Siriphorn Rotarayanont, Thanich Sangsuwannukul, Nattaporn Phanthaphol, Yupanun Wutti-in, Chalermchai Somboonpatarakun, Thaweesak Chieochansin, Mutita Junking, Jatuporn Sujjitjoon, Pa-thai Yenchitsomanus, Aussara Panya

“…Our findings suggest combination gemcitabine and PD-L1xCD3 BiTE as a potential alternative therapy for CCA.…”
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