How to survive the mutational meltdown: lessons from plant RNA viruses by Lafforgue, Guillaume, Lefebvre, Marie, Michon, Thierry, Elena, Santiago F.

“…We observed three distinct evolutionary outcomes for tobacco etch virus under three different demographic conditions: (i) a decline in fitness following periodic severe bottlenecks in Chenopodium quinoa, (ii) a consistent fitness level with moderate bottlenecks in C. quinoa, and (iii) a net increase in fitness when severe bottlenecks in C. quinoa were alternated with large population expansions in Nicotiana tabacum. …”
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Professional experiences on use of the mental health act in ethnically diverse populations: a photovoice study by Roisin Mooney, Paul McCrone, Rose McCabe, Kamaldeep Bhui, Brian Brown, Colin King, Andrew Molodynski, Nusrat Husain, Jacqueline Sin, Karen Newbigging, Michael Larkin, Neil Caton, Raghu Raghavan, Doreen Joseph, Anthony Zigmond, Michelle Yeung, Julie Carr, Phuong Hua, Frank Keating, Tara Morey, Claire Dempsey, Rahul Battacharya, Nuwan Dissanyake, Rochelle Ramkisson, Laura Dixon, Kopal Tandon, Gary Roberts, Paul Illingworth, Jo White, Karen Persaud, Sayeeda Basharat, Tripti Kandia, Sandra Griffiths, Michael Molete

“…Legislative compliance in a crisis conflicted with supportive and recovery-orientated care.Conclusion Clear standards are needed, including specific protocols for MHA assessment, police interactions, alternatives to admission, early intervention and continuity of care.…”
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VSIG4+ tumor-associated macrophages mediate neutrophil infiltration and impair antigen-specific immunity in aggressive cancers through epigenetic regulation of SPP1 by Zongfu Pan, Jinming Chen, Tong Xu, Anqi Cai, Bing Han, Ying Li, Ziwen Fang, Dingyi Yu, Shanshan Wang, Junyu Zhou, Yingying Gong, Yulu Che, Xiaozhou Zou, Lei Cheng, Zhuo Tan, Minghua Ge, Ping Huang

“…Overall, our studies demonstrate the epigenetic regulation function of VSIG4 confers on TAMs an alternative pattern, beyond the checkpoint role of VSIG4, to shape the immunosuppressive tumor microenvironment and impair antigen-specific immunity against aggressive cancers. …”
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Phytoreduced gold nanoparticles from vitalmelon promote white adipocyte browning in murine cells by targeting phospholipase D2 by Sun Young Park, He mi Kang, Kangmin Park, Lu Guo, Jin-Woo Oh, Geuntae Park, Nam Jun Kang, Young-Whan Choi

“…Recent advancements in green nanotechnology have enabled the synthesis of nanoparticles using natural resources, thereby offering ecofriendly alternatives for various biomedical applications. In this study, we report the biosynthesis of gold nanoparticles (GNPs) using vitalmelon (VW) extract (VW-GNPs) without the need for stabilizers or surfactants. …”
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A Feasibility Analysis of Wind Energy Potential and Seasonal Forecasting Trends in Thatta District: A Project to Combat the Energy Crisis in Pakistan by Jahangeer Khan Bhutto, Zhijun Tong, Tayyab Raza Fraz, Mazhar Baloch, Haider Ali, Jiquan Zhang, Xingpeng Liu, Yousef A. Al-Masnay

“…Wind energy has emerged as a viable alternative to fossil fuels due to its clean and cost-effective nature. …”
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The effect of resizing on the natural appearance of scintigraphic images: an image similarity analysis by Siraj Ghassel, Amir Jabbarpour, Jochen Lang, Eric Moulton, Eric Moulton, Ran Klein, Ran Klein, Ran Klein, Ran Klein

“…Naïve upsampling and downsampling with linear interpolation were compared against alternative methods based on the preservation of Poisson count statistics and principles of nuclear scintigraphic imaging; namely, linear interpolation with a Poisson resampling correction (upsampling) and a sliding window summation method (downsampling). …”
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Green synthesis and characterization of CuO/ZnO nanocomposite using Musa acuminata leaf extract for cytotoxic studies on colorectal cancer cells (HCC2998) by Wong Yee Jin, Subramaniam Hemaroopini, Shing Wong Ling, Dhanapal Anto Cordelia Tanislaus Antony, Chan Yu Bin, Aminuzzaman Mohammod, Tey Lai-Hock, Janakiraman Ashok Kumar, Kayarohanam Saminathan, Djearamane Sinouvassane

“…Green synthesis has become an alternative to replace chemical synthesis in nanotechnology because of its low cost and toxicity. …”
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Toward Integrating ChatGPT Into Satellite Image Annotation Workflows: A Comparison of Label Quality and Costs of Human and Automated Annotators by Jacob Beck, Lukas Malte Kemeter, Konrad Durrbeck, Mohamed Hesham Ibrahim Abdalla, Frauke Kreuter

“…We evaluate the feasibility and economic competitiveness of using the ChatGPT4-V model for a complex land usage annotation task and compare it with alternative human annotators. A set of satellite images is annotated by a domain expert and 15 additional human and automated annotators, differing in expertise and costs. …”
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Preparation of recombinant myoglobin and investigation of the liquid antigen stability for quality control materials by Yu-Hui Wang, Xi-Feng Sun, Chun-Xin Xu, Feng-Qiang Sun, Rong-Rong Wang, Xiao-Kun Bian, Zhan-Zhao Wang, Qiang Wu

“…It was a promising alternative as the quality control material for Mb detection.…”
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Excitation and Propagation of Longitudinal L (0, 2) Mode Ultrasonic Guided Waves for the Detection of Damages in Hexagonal Pipes: Numerical and Experimental Studies by Xiang Wan, Meiru Liu, Xuhui Zhang, Hongwei Fan, Qinghua Mao, Ming Dong, Xing Wang, Hongwei Ma

“…Our study results have demonstrated that the use of longitudinal L (0, 2) mode ultrasonic guided wave provides a promising and effective alternative for the detection of defects in hexagonal pipe structures.…”
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Pseudomonas azotoformans and Pseudomonas putida: Novel kiwifruit-native biological control agents against Pseudomonas syringae pv. actinidiae by Cristiana Correia, Antonio Cellini, Irene Donati, Panagiotis Voulgaris, Adebayo Ebenezer Obafemi, Elia Soriato, Elodie Vandelle, Conceição Santos, Francesco Spinelli

“…Though environment-friendly disease control methods based on biological control agents (BCAs) represent a promising alternative to xenobiotic pesticides, their efficacy in field conditions has often resulted erratic. …”
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Treatment Effects of Upper Limb Action Observation Therapy and Mirror Therapy on Rehabilitation Outcomes after Subacute Stroke: A Pilot Study by Yu-Wei Hsieh, Yu-Hsuan Lin, Jun-Ding Zhu, Ching-Yi Wu, Yun-Ping Lin, Chih-Chi Chen

“…The preliminary results found that the patients in the action observation therapy and active control intervention groups had comparable benefits, suggesting that the 2 treatments might be used as an alternative to each other. A further large-scale study with at least 20 patients in each group to validate the study findings is needed. …”
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The Potential Effect of Bualuang (White <i>Nelumbo nucifera</i> Gaertn.) Extract on Sperm Quality and Metabolomic Profiles in Mancozeb-Induced Oxidative Stress in Male Rats by Jiraporn Laoung-on, Pimchanok Nuchniyom, Ketsarin Intui, Churdsak Jaikang, Kanokporn Saenphet, Kongsak Boonyapranai, Giatgong Konguthaithip, Nopparuj Outaitaveep, Sasitorn Phankhieo, Paiwan Sudwan

“…WNPE should be considered as an alternative dietary supplement that can protect against MZ toxicity and enhance sperm quality in the male rat reproductive system.…”
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Evaluation of external and radiological landmark methods for optimizing ultrasound-guided right internal jugular venous catheterization depth in cardiac surgery by Artid Samerchua, Panuwat Lapisatepun, Pattaranee Srichairatanakool, Tanyong Pipanmekaporn, Wariya Sukhupragarn, Settapong Boonsri, Nutchanart Bunchungmongkol, Lalita Huntrakul

“…External landmark-based and radiological landmark-based methods have been proposed as alternatives to estimate the insertion depth. This study aimed to evaluate these methods using transesophageal echocardiography (TEE)-guided insertion depth as the reference. …”
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Regeneration of Rabbit Auricular Cartilage After the Intravenous Stem Cell Injection by Pavlo Virych, Nadiia Shuvalova, Anton Karas, Galina Karas, Svitlana Chaika, Tetiana Kucherenko, Ganna Minina, Marina Timchenko, Oleg Melnykov, Yurii Minin

“…The low regenerative capacity of cartilage requires alternative approaches such as cell and tissue engineering. …”
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Conjugated Linoleic Acid Treatment Attenuates Cancerous features in Hepatocellular Carcinoma Cells by Zohre Miri-Lavasani, Shukoofeh Torabi, Roya Solhi, Bahareh Shokouhian, Parvaneh Afsharian, Zahra Heydari, Abbas Piryaei, Zahra Farzaneh, Nikoo Hossein-khannazer, Hamidreza Aboulkheyr Es, Ensieh Zahmatkesh, Andreas Nussler, Moustapha Hassan, Mustapha Najimi, Massoud Vosough

“…A growing number of hepatocellular carcinoma (HCC), and recurrence frequency recently have drawn researchers’ attention to alternative approaches. The concept of differentiation therapies (DT) relies on inducing differentiation in HCC cells in order to inhibit recurrence and metastasis. …”
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Effectiveness of dupilumab treatment against refractory eosinophilic chronic rhinosinusitis by Daiki Nakashima, MD, Tsuguhisa Nakayama, MD, PhD, Shunsuke Minagawa, MD, PhD, Tetsuya Adachi, MD, PhD, Chieko Mitsuyama, MD, Yoko Shida, MD, Tsuneya Nakajima, MD, PhD, Shin-ichi Haruna, MD, PhD, Yoshinori Matsuwaki, MD, PhD

“…Conclusions: Dupilumab shows effectiveness in treating ECRS and could serve as an alternative therapeutic option to systemic corticosteroids. …”
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Improving prognostic evaluations in patients with stage IIIb light chain cardiac amyloidosis: role of haemodynamic parameters by Jingyi Li, Yang Lu, Xiqi Xu, Zhuang Tian, Jian Li, Shuyang Zhang

“…Our findings suggest that echocardiography-derived PASP could alternatively reflect the PAWP/CI ratio.…”
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Taenia crassiceps-Excreted/Secreted Products Induce a Defined MicroRNA Profile that Modulates Inflammatory Properties of Macrophages by Diana Martínez-Saucedo, Juan de Dios Ruíz-Rosado, César Terrazas, Blanca E. Callejas, Abhay R. Satoskar, Santiago Partida-Sánchez, Luis I. Terrazas

“…Our previous studies indicate that Taenia crassiceps-excreted/secreted antigens (TcES) downregulate inflammatory responses in rodent models of autoimmune diseases, by promoting the generation of alternatively activated-like macrophages (M2) in vivo. …”
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Mesenchymal Stem Cell-Derived Extracellular Vesicles for Regenerative Applications and Radiotherapy by Ning Wang, Feifei Ma, Huijuan Song, Ningning He, Huanteng Zhang, Jianguo Li, Qiang Liu, Chang Xu

“…In tissue damage, EVs can be used as an alternative to stem cell therapy, thereby avoiding related complications such as immunological rejection. …”
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