Establishment and Validation of a New Predictive Model for Insulin Resistance based on 2 Chinese Cohorts: A Cross-Sectional Study by Shi Zhang, Xin-Cheng Wang, Jing Li, Xiao-He Wang, Yi Wang, Yan-Ju Zhang, Mei-Yang Du, Min-Ying Zhang, Jing-Na Lin, Chun-Jun Li

“…Visceral adiposity plays a key role in the development of insulin resistance (IR), so surrogate index that can indicate visceral obesity may have higher predictive value for IR. …”
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Hepatoprotective effects of propolis ethanol extract on D-galactose-induced aging mice: A metabolomics and transcriptomics analysis focusing on insulin resistance pathways by Jinjia Liu, Songhao Tian, Jixiang Wang, Qing Sang, Wenting Su, Jinqiang Wu, Fenglei Zai

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Ultrathin Anode Buffer Layer for Enhancing Performance of Polymer Solar Cells by Dun Wang, Jian Wang, Ling-liang Li, Qiao-shi An, Hui Huang, Chao-qun Jiao, Yang Liu, Fu-jun Zhang

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Verbascoside exerts an anti-atherosclerotic effect by regulating liver glycerophospholipid metabolism by Peng Lei, Jialin Lü, Tie Yao, Peng Zhang, Xin Chai, Yuefei Wang, Miaomiao Jiang

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Nonalcoholic Fatty Liver Disease as a Potential Risk Factor for Cardiovascular Disease in Patients with Type 2 Diabetes: A Prospective Cohort Study by Mohammad Dehghani Firouzabadi, Amirhossein Poopak, Ali Sheikhy, Fatemeh Dehghani Firouzabadi, Fatemeh Moosaie, Soghra Rabizadeh, Sara Momtazmanesh, Manouchehr Nakhjavani, Alireza Esteghamati

“…Although the etiology of NAFLD is unknown, insulin resistance is a key mechanism of lipid deposition in hepatocytes leading to steatosis and potentially steatohepatitis in patients with diabetes. …”
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Effects of Curcumin on Iron Overload in Rats by Gülüzar Özbolat, Arash Alizadeh Yegani

“… Background: Iron overload, common in patients with hematological disorders, is a key target in drug development. This study investigated the effects of curcumin on iron overload in rats. …”
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Thiacloprid exposure disrupts the gut-liver axis and induces liver dysfunction in the Reeves' turtles (Mauremys reevesii) by Shuqin Lin, Yunjuan Xiao, Siyu Li, Liyan Tang, Haitao Shi, Meiling Hong, Li Ding

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A New Strain of Preponderant Amphitriploid Carassius Clone Juvenile With Integrated Genomes Partly From White Crucian Carp (C. auratus cuvieri) Requires Low Dietary Protein by Xing Wang, Dong Han, Junyan Jin, Xiaoming Zhu, Haokun Liu, Zhimin Zhang, Yunxia Yang, Shouqi Xie

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Bisphenol S Induces Lipid Metabolism Disorders in HepG2 and SK-Hep-1 Cells via Oxidative Stress by Kai-Xing Lin, Zi-Yao Wu, Mei-Lin Qin, Huai-Cai Zeng

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Ningxiang pig-derived Lactobacillus reuteri improves the gut health of weaned piglets by regulating intestinal barrier function and cytokine profiles by Qian Xie, Mei Yang, Qing Duanmu, Meng Kang, Jing Wang, Bi E Tan

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The effect of thymus vulgaris extract and probiotic on growth performance, blood parameters, intestinal morphology, and litter quality of broiler chickens fed low-protein diets by Ali Golshahi, Mahmoud Shams Shargh, Behrouz Dastar, Enayat Rahmatnejad

“…ALP and ALT levels dropped with low-CP × TVE and normal diet × probiotic, respectively (P < 0.05). …”
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Hepatitis due to Coxsackie A virus in an adult: a case report by Likith Surendra, Varun Sharma, Milan Sivakumar, Tara Lanzendorf, Thomas C. Varkey, Kaivan Salehpour

“…The day after presentation, AST increased to 694 U/L, and ALT increased to 594 U/L. Physical examination, abdominal imaging, and laboratory testing for classic viral causes of hepatitis were unremarkable. …”
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Efficacy of Tenofovir-Based Combination Therapy versus Tenofovir Monotherapy in Chronic Hepatitis B Patients Presenting with Suboptimal Responses to Pretreatment: A Meta-Analysis by Ling Chen, Xiwei Wang, Qiongfang Zhang, Jiaojiao Gong, Shasha Shen, Wenwei Yin, Huaidong Hu

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Sodium butyrate attenuates oxidative stress, apoptosis, and excessive mitophagy in sodium fluoride-induced hepatotoxicity in rats by Jing Xia, Xiaolin Zhang, Leiyu Xu, Nan Yan, Zhenxiang Sun, Xiaoxu Duan, Lu Meng, Rong Qi, Fu Ren, Zhengdong Wang

“…Methods: Rats were randomly divided into four groups of 12 male rats each: control, NaF (100 mg/mL), NaB (1000 mg/kg), and NaF (100 mg/mL)+NaB (1000 mg/kg) group. Key findings: Changes in the levels of liver enzymes (alanine aminotransferase [ALT] and aspartate aminotransferase [AST]) and antioxidant enzymes (superoxide dismutase [SOD], catalase [CAT], and malondialdehyde [MDA]) confirmed NaF-induced liver injury. …”
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Comprehensive Assessment of Rapeseed Meal as a Fish Meal Substitute in Hybrid Sturgeon (Acipenser schrenckii ♀ × Acipenser baerii ♂) Diets: Impacts on Growth Performance, Body Comp... by Wenpeng Zhang, Siyuan Liu, Shidi Wang, Huamin Wang, Kaibo Ge, Yuhong Yang, Shaoxia Lu, Shicheng Han, Haibo Jiang, Chang’an Wang, Hongbai Liu

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Dietary γ-Aminobutyric Acid Promotes Growth and Immune System Performance and Improves Erythropoiesis and Angiogenesis in Gibel Carp (<i>Carassius auratus gibelio</i>) by Xinlan Bai, Lu Zhang, Hualiang Liang, Dongyu Huang, Mingchun Ren, Haifeng Mi

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Changes induced in mouse lipid metabolism by simultaneous impact of antisense oligonucleotide derivatives to <i>apoB</i>, <i>PCSK9</i>, and <i>apoCIII</i> mRNAs by S. I. Oshevski, Y. I. Ragino, E. V. Kashtanova, Y. V. Polonskaya, E. M. Stakhneva, V. P. Nikolin, N. A. Popova, N. A. Kolchanov, M. I. Voevoda

“…The goal of the work was to assess the changes in the lipid metabolism caused by variants of joint impact of the ASOs targeted to the mRNAs of its key genes: apoB, PCSK9, and apoCIII. Female C57BL/6J mice; nuclease-protected 13- and 20-nucleotide ASOs, and standard protocols for quantification of lipoproteins (HDL CHL, non-HDL CHL, and total CHL) and ALT in the blood serum were used in the work. …”
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Hepatoprotective Potential of Sargassum muticum against STZ-Induced Diabetic Liver Damage in Wistar Rats by Inhibiting Cytokines and the Apoptosis Pathway by Mohammed M. Safhi, Mohammad Firoz Alam, Sivagurunathan Moni Sivakumar, Tarique Anwer

“…Thus, the MESM plays a key role in rejuvenating the liver and can modulate diabetes’s pathogenic effect by reducing the glucose level.…”
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Phase I study of pembrolizumab in combination with ibrutinib for the treatment of unresectable or metastatic melanoma by Yuan Yao, Yiyi Yan, Vera J. Suman, Allan B. Dietz, Courtney L. Erskine, Anastasios Dimou, Svetomir N. Markovic, Svetomir N. Markovic, Robert R. McWilliams, Heather N. Montane, Matthew S. Block, Matthew S. Block

“…The adverse events leading to discontinuation included: grade 4 ALT and AST increase (1 pt, DL0); grade 4 ALT increase with grade 3 AST increase (1 pt, DL1); and grade 3 hyponatremia, hypoxia, and maculo-papular rash (1 pt, DL1). …”
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Delving into biomarkers and predictive modeling for CVD mortality: a 20-year cohort study by Zhen Wu, Abdullahi Mohamud Hilowle, Ying Zhou, Changlin Zhao, Shuo Yang

“…Cox regression analysis further identified key predictors of CVD mortality, including elevated AST/ALT, TyG, BUN, and systolic blood pressure, with protective factors such as higher chloride and iron levels. …”
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