Inflammasomes in neurodegenerative diseases by Qianchen Wang, Songwei Yang, Xuan Zhang, Shanshan Zhang, Liping Chen, Wanxue Wang, Naihong Chen, Jiaqing Yan

“…In neurodegenerative diseases and neuroinflammation, the accumulation of misfolded proteins, such as beta-amyloid and alpha-synuclein, can lead to inflammasome activation, resulting in the release of interleukin (IL)-1β and IL-18. …”
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Network pharmacology and experimental verification to investigate the mechanism of isoliquiritigenin for the treatment of Alzheimer’s disease by Waimao Gao, Guang Yang, Xinjuan Liu, Kaifan Hu, Jie Pan, Xingyu Wang, Yan Zhao, Ying Xu

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Insights into COVID-19 Delta variant (B.1.617.2) by Angel Yun-Kuan Thye, Ke-Yan Loo, Kyle Bond Chene Tan, Jenny May-Sim Lau, Vengadesh Letchumanan

“…It caught worldwide attention due to its greater transmissibility than the progenitor strain and the first variant of concern (VOC)- Alpha variant (B.1.1.7). …”
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Gravitational wave luminosity distance for Starobinsky gravity in viscous cosmological models by Jia-nan Chi, Ya-Bo Wu, Yu Sang, Xue Zhang, Yi-liang Hu, Wen-zhong Liu, Bo-hai Chen

“…Evidently, both of them are affected by $$\alpha $$ α and $$\eta $$ η . It worth stressing that the results given by us can reduce to ones in documents [13, 22, 30]. …”
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Distinctive Gut Microbiota Alteration Is Associated with Poststroke Functional Recovery: Results from a Prospective Cohort Study by Yini Dang, Xintong Zhang, Yu Zheng, Binbin Yu, Dijia Pan, Xiaomin Jiang, Chengjie Yan, Qiuyu Yu, Xiao Lu

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Ethyl Acetate Extract of <i>Cichorium glandulosum</i> Activates the P21/Nrf2/HO-1 Pathway to Alleviate Oxidative Stress in a Mouse Model of Alcoholic Liver Disease by Shuwen Qi, Chunzi Zhang, Junlin Yan, Xiaoyan Ma, Yewei Zhong, Wenhui Hou, Juan Zhang, Tuxia Pang, Xiaoli Ma

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Dietary protein requirement of Chinese hook snout carp (Opsariichthys bidens) and transcriptomic analysis of the liver in response to different protein diets by Yijiang Bei, Linqiang He, Jin Jing, Xiaoming Chen, Fan Yuan, Gaohua Yao, XueYan Ding, Lei Wang, Fan Zhou

“…Compared with those in the P41 group, some genes related to the digestive system (e.g., carboxypeptidases, elastase 2, trypsin-2, and bile salt-activated lipase) and immune response (e.g., NF-kappa B inhibitor alpha, tumor necrosis factor alpha-induced protein 3, complement C3, and C7) were significantly upregulated in the P47 group. …”
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Pirfenidone Inhibits Hypoxic Pulmonary Hypertension through the NADPH/ROS/p38 Pathway in Adventitial Fibroblasts in the Pulmonary Artery by Song Zhang, ZongXiu Yin, WeiDong Qin, XiaoLi Ma, Yao Zhang, EnXiu Liu, YanBiao Chu

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Translation and cultural adaption of MacLeod Clark professional identity scale among Chinese therapy students. by Xiaoyi Shu, Chun Feng, Chak-Lam Ip, Xin Zhang, Nan Yang, Shibo Li, Jia Han, Weibing Wu, Alec Knight

“…Model fit was evaluated through confirmatory factor analysis (CFA) using the Comparative Fit Index (CFI), Tucker-Lewis Index (TLI), Standardized Root Mean Square Residual (SRMR) and Root Mean Square of Error of Approximation (RMSEA). …”
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A Transcriptomic Analysis Reveals Diverse Regulatory Networks That Respond to Cold Stress in Strawberry (Fragaria×ananassa) by Yong Zhang, Yunting Zhang, Yuanxiu Lin, Ya Luo, Xiaorong Wang, Qing Chen, Bo Sun, Yan Wang, Mengyao Li, Haoru Tang

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Betaine Inhibits NLRP3 Inflammasome Hyperactivation and Regulates Microglial M1/M2 Phenotypic Differentiation, Thereby Attenuating Lipopolysaccharide-Induced Depression-Like Behavi... by Man Zhang, Xiao-Long Wang, Hui Shi, Lan-Qing Meng, Hong-Feng Quan, Lin Yan, Hui-Fang Yang, Xiao-Dong Peng

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Efficacy, safety, and biomarker analysis of TACE combined with lenvatinib plus sintilimab in unresectable hepatocellular carcinoma: a real-world study by Lingzhan Meng, Hu Li, Yingjie Ji, Peng Yu, Zizheng Wang, Li Cao, Bin Shi, Yanling Shao, Jin Yan, Yinjie Gao, Zhenyu Zhu

“…The median PFS was 13.2 months (95% CI 11.0-NA), with a corresponding 1-year PFS rate of 50.3% (95% CI 39.7%-65.5%). …”
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Exposure to triphenyl phosphate during pregnancy: The role of gut-bile acids-liver axis on lipid metabolism in male offspring by Juntong Lin, Fuhui Yan, Longhui Liu, Ganzhong Liao, Yilei Xu, Qian Liu, Miaoliang Wu, Honghui Guo, Bai Zhi, Lianxian Guo, Xiaoshan Liu

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Cross-Cultural Adaptation and Validation of the Hong Kong Version of the Knee Injury and Osteoarthritis Outcome Score (HK-KOOS) for Patients with Knee Osteoarthritis by Andy S. K. Cheng, Ka-chun Chan, Sum-yuet Chan, Miu-kwan Fan, Man-kwan Fung, Oi-yan Lee, Cindy T. T. Kwok, Jackson K. K. Wong

“…Test-retest reliability and internal consistency were assessed by the Intraclass Correlation Coefficient (ICC) and Cronbach’s alpha. Dimensionality was assessed by performing exploratory factor analysis (EFA). …”
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Changes of Regulatory T Cells and of Proinflammatory and Immunosuppressive Cytokines in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis by Yong-chao Qiao, Jian Shen, Lan He, Xue-zhi Hong, Fang Tian, Yan-hong Pan, Ling Liang, Xiao-xi Zhang, Hai-lu Zhao

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Mechanism of dexmedetomidine protection against cisplatin induced acute kidney injury in rats by Zeng-lu Zheng, Jun-wei Ma, Yi Luo, Gui-jin Liang, Shi-jie Lei, Ke-jin Yan, Hai-bing Meng, Xiu-juan Liu

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Integrative bioinformatic approach reveals novel melatonin-related biomarkers for Alzheimer’s disease by Hua-xiong Zhang, Dilmurat Hamit, Qing Li, Xiao Hu, San-feng Li, Fu Xu, Ming-yuan Wang, Guo-qing Bao, Hong-yan Li

“…Abstract Background: Melatonin (MLT) can improve mitophagy, thereby ameliorating cognitive deficits in Alzheimer’s disease (AD) patients. …”
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Emodin Ameliorates Intestinal Dysfunction by Maintaining Intestinal Barrier Integrity and Modulating the Microbiota in Septic Mice by Mina Zhang, Bo Lian, Rui Zhang, Yuhong Guo, Jingxia Zhao, Shasha He, Yunjing Bai, Ning Wang, Yan Lin, Xuerui Wang, Qingquan Liu, Xiaolong Xu

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Colorectal cancer in Lynch syndrome families: consequences of gene germline mutations and the gut microbiota by Xuexin Wang, Zhijun Zheng, Dongliang Yu, Xiaojue Qiu, Ting Yang, Ruoran Li, Jing Liu, Xin Wang, Peng Jin, Jianqiu Sheng, Nan Qin, Na Li, Junfeng Xu

“…We enrolled 72 individuals from 9 LS families across six provinces in China and employed 16S rRNA gene amplicon sequencing to analyze the fecal microbiota components among LS-related CRC patients (AS group), their spouses (BS group), mutation carriers without CRC (CS group), and non-mutation carriers (DS group) using alpha and beta diversity indices. …”
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Fluoride exposure, personal susceptibility and osteoarticular degeneration: Evidence from farmers in the Yellow River Basin of Henan Province by Zichen Feng, Long Sun, Shu Niu, Bin Liu, Ruijie Ba, Guoqing Wang, Qing Sun, Chunxiang Li, Yan Wang, Fangfang Yu, Guoyu Zhou, Yue Ba

“…Osteoarticular degeneration (OAD) is an important issue. Excessive fluoride can damage osteoarticular health. Besides, personal susceptibility (including genetic factors, physiological characteristics, and lifestyle) also contributes to osteoarticular development significantly. …”
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