Prognostic value of multi-PLD ASL radiomics in acute ischemic stroke by Zhenyu Wang, Yuan Shen, Xianxian Zhang, Qingqing Li, Congsong Dong, Shu Wang, Haihua Sun, Mingzhu Chen, Xiaolu Xu, Pinglei Pan, Pinglei Pan, Zhenyu Dai, Fei Chen, Fei Chen

Subjects: “…acute ischemic stroke…”
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Targeting enolase 1 reverses bortezomib resistance in multiple myeloma through YWHAZ/Parkin axis by Xuejie Gao, Qilin Feng, Qikai Zhang, Yifei Zhang, Chaolu Hu, Li Zhang, Hui Zhang, Guanli Wang, Ke Hu, Mengmeng Ma, Zhuning Wang, Yujie Liu, Dong An, Hongfei Yi, Yu Peng, Xiaosong Wu, Gege Chen, Xinyan Jia, Haiyan Cai, Jumei Shi

“…Furthermore, combination treatment with bortezomib and pharmaceutical agents targeting ENO1 has synergistic anti-MM effects both in vivo and in vitro. …”
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A network comparison on efficacy and safety profiling of PD-1/PD-L1 inhibitors in first-line treatment of advanced non-small cell lung cancer by Jie Fu, Jie Fu, Yi-Dan Yan, Xu Wan, Xiao-Fan Sun, Xiao-Fan Sun, Xiu-Mei Ma, Ying-Jie Su

“…ObjectivePD-1/PD-L1 inhibitors are novel immunotherapeutic agents that have been approved for first-line treatment in advanced non-small cell lung cancer (NSCLC). …”
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Influence of Dentin Priming with Tannin-Rich Plant Extracts on the Longevity of Bonded Composite Restorations by Mackeler Ramos Polassi, Thales de Sá Oliveira, Ana Calheiros de Carvalho, Lívia Soman de Medeiros Medeiros, Thiago André Moura Veiga, Carlos Frederico de Oliveira Graeff, Alejandra Hortencia Miranda González, Maria Cristina Marcucci, Simone dos Santos Grecco, Paulo Henrique Perlatti D’Alpino

“…This in vitro study evaluated the influence of bioactive plant extracts as dentin biomodifying agents to improve the longevity of bonded restorations. …”
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HERITAGE LANGUAGE EDUCATION IN ITALY: FIRST SURVEY AS PART OF A EUROPEAN PROJECT by Giuseppe Sergio

“…L’educazione alle lingue ereditarie in Italia: prima indagine nell’ambito di un progetto europeo L’articolo presenta il report di un progetto pilota europeo intitolato Heritage language education in Europe: Legislative and educational challenges, promosso nel 2022 nell’ambito dell’Alleanza 4EU+. L’articolo propone alcune prime investigazioni sulla situazione italiana, considerata sia dal punto di vista legislativo sia da quello delle pratiche attuate. …”
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PDL1 inhibitors may be associated with a lower risk of allograft rejection than PD1 and CTLA4 inhibitors: analysis of the WHO pharmacovigilance database by Alexandre O. Gérard, Alexandre O. Gérard, Alexandre O. Gérard, Diane Merino, Diane Merino, Jonathan Benzaquen, Alexandre Destere, Delphine Borchiellini, Clément Gosset, Clément Gosset, Fanny Rocher, Marine Andreani, Charles-Hugo Marquette, Henri Montaudié, Henri Montaudié, Milou-Daniel Drici, Antoine Sicard, Antoine Sicard

“…Immune checkpoint inhibitors (ICI) have improved survival rates, but data on the use of these agents in transplant recipients is scarce. ICI may trigger allograft rejection, but the absolute risk of AR between the different ICI classes remains to be defined.MethodsVigiBase® (WHO’s pharmacovigilance database) was queried for reports of AR involving CTLA4, PD1, or PDL1 inhibitors. …”
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Effects of Glucagon-Like Peptide-1 Receptor Agonists on Weight Loss in Patients with Type 2 Diabetes: A Systematic Review and Network Meta-Analysis by Feng Sun, Sanbao Chai, Lishi Li, Kai Yu, Zhirong Yang, Shanshan Wu, Yuan Zhang, Linong Ji, Siyan Zhan

“…Network meta-analysis found that EX10BID, LIR1.8QD, and EX2QW obtained a higher proportion of patients with weight loss than other traditional hypoglycemic agents. Our results suggest GLP-1 RAs are promising candidates for weight control in comparison with traditional hypoglycemic drugs, and EX10BID, LIR1.8QD, and EX2QW rank the top three drugs.…”
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Flavonoids and anthocyanins in seagrasses: implications for climate change adaptation and resilience by Jana Botes, Jana Botes, Xiao Ma, Xiao Ma, Jiyang Chang, Jiyang Chang, Yves Van de Peer, Yves Van de Peer, Yves Van de Peer, Yves Van de Peer, Dave Kenneth Berger, Dave Kenneth Berger

“…Flavonoids will likely prove to be effective and versatile agents in combating the new host of stress conditions introduced to marine environments by anthropogenic climate change, which affects marine environments differently from terrestrial ones. …”
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Canadian Rhinology Working Group consensus statement: biologic therapies for chronic rhinosinusitis by Andrew Thamboo, S. Kilty, I. Witterick, Y. Chan, C. J. Chin, A. Janjua, A. Javer, J. Lee, E. Monterio, B. Rotenberg, J. Scott, K. Smith, D. D. Sommer, L. Sowerby, M. Tewfik, E. Wright, M. Desrosiers

“…Therefore, biologics, monoclonal antibody agents, could be beneficial therapeutic treatments for these patients. …”
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Evaluación ecotoxicológica de los residuos de Lippia alba Mill. sobre Eisenia andrei (lombriz de tierra) by Ana Cristina Noa Rodríguez, Yordanka Domínguez Linares, Yamilet Irene Gutiérrez Gaitén, Odette Beiro Castro, Maydelín Díaz González, Ramón Scull Lizama, Jorge Carlos Castillo Miranda, Alejandro Felipe González

“…Introducción: Lippia alba es una planta distribuida por todo el mundo. Sus aceites esenciales y extractos se usan en diversas formulaciones farmacéuticas y cosméticas, entre ellas, fricciones antiinflamatorias. …”
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Donafenib combined with sintilimab for advanced hepatocellular carcinoma: a single arm phase II trial by Xiaoyang Hong, Yongjian Guo, Wenbo Shi, Kangshun Zhu, Licong Liang, Liteng Lin, Ye Chen, Jingwen Zhou, Jingjun Huang, Jiabai Huang, Yaozhu Wu, Wensou Huang, Mingyue Cai

“…Abstract Background Previous studies evaluating antiangiogenic agents plus immune checkpoint inhibitors for unresectable hepatocellular carcinoma (HCC) have shown encouraging results. …”
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TYRO3 blockade enhances anti-PD-1 therapy response by modulating expression of CCN1 in tumor microenvironment by Miso Park, Da-Sol Kuen, Keon Wook Kang, Yeonseok Chung, Jaewoo Park, Munkyung Choi, Yeonji Kim, Eun Chae Roh, Yong June Choi, Yoon Gyoon Kim, Sung Yun Cho

“…Background Immunological contexture differs across malignancies, and understanding it in the tumor microenvironment (TME) is essential for development of new anticancer agents in order to achieve synergistic effects with anti-programmed cell death protein-1 (PD-1) therapy. …”
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Safety and efficacy of dual versus triple antithrombotic therapy (DAT vs TAT) in patients with atrial fibrillation following a PCI: a systematic review and network meta-analysis by Abdulaali R Almutairi, Renad M Altoukhi, Reema A Alshouimi, Shahad M Al Rammah, Mohammed Y Alzahrani, Abdulmajeed M Alshehri, Osamah M Alfayez, Majed S Al Yami, Omar A Almohammed

“…However, ranking probabilities for the best option in the selected outcomes can be used to guide the selection among these agents based on different patients’ conditions.…”
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Acciones independientes dirigidas al cuidado y promoción de la Diabetes Mellitus en la Atención primaria de salud, apoyada en la teoría de Hildegart Elizabeth Peplau. by Taimi Nereida Rodríguez Abrahantes, Taimy Alfonso Moré, Taimy Alfonso Moré, Arahy Rodríguez Abrahantes, Arahy Rodríguez Abrahantes, Geidy Caridad Cabrera Suris, Geidy Caridad Cabrera Suris, Tamara Lanza Llerena, Tamara Lanza Llerena, Yoan Cepero Santana, Yoan Cepero Santana

“…Los hábitos nutricionales inadecuados (85,71%), el sedentarismo (84,52%) el hábito de fumar (55,38%) fueron los factores de riesgo modificables que más incidieron, más del 60% de la muestra poseían un nivel de información inadecuado sobre la enfermedad y autocuidados; predominaron las relaciones interpersonales evaluadas de aceptables (52,38%). Conclusiones: Se propusieron un conjunto de acciones independientes de enfermería dirigidas al cuidado y promoción de pacientes diabéticos tipo 2 sobre la base de la teoría de las relaciones interpersonales de Hildegart Elizabeth Peplau.…”
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Candidiasis mucocutánea crónica, infecciones micobacterianas y rosácea en un adulto mexicano con aumento de la función en STAT1 by Valeria Valerio-Gómez, Uriel Pérez-Blanco, Guillermo Velázquez-Sámano, Andrea Aída Velasco-Medina, Antonio Albarrán, Itzel Yoselín Sánchez, Laura Berrón-Ruiz, Sara Espinosa-Padilla, Lizbeth Blancas-Galicia

“…La vía de señalización JAK/STAT, mediada por el interferón, participa en la eliminación de agentes patógenos intracelulares y virus. Las variantes patógenas de STAT1 pueden producir una función deficiente o incrementada. …”
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Nina Façon despre Giordano Bruno by Smaranda Bratu Elian

“…Si tratta dei due saggi di esegesi filosofica, pubblicati sotto due diversi pseudonimi nel 1942: L’attivismo nel pensiero del Rinascimento italiano (divenuto in un volume ulteriore La concezione dell’uomo attivo) e lo studio introduttivo alla propria traduzione del dialogo bruniano De la causa, principio et uno; e di un terzo studio, Su alcune parolechiave in Giordano Bruno, pubblicato nel 1969 sulla Rivista Scientifica dell’Università Humboldt di Berlino, che è di carattere storico-linguistico. …”
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Cytoreductive Nephrectomy and Nephrectomy/Complete Metastasectomy for Metastatic Renal Cancer by Paul Russo, Mark Synder, Andrew Vickers, Varuni Kondagunta, Robert Motzer

“…This surgical experience provides a contemporary foundation as new targeted therapeutic agents are integrated into the neoadjuvant or adjuvant treatment of locally advanced and metastatic renal cancer.…”
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Bacterial profiling of mask waste from terrestrial and marine environment by A. Rakhmawati, B. Octavia, S. Marwati, D. Kristanti

“…The ability to produce biofilms, withstand antibiotics, and endure heavy metal ions provides a protective environment for bacteria, enhancing their resilience against environmental stresses, and antimicrobial agents. Analysis of bacterial profiles reveals the intricate connections between microorganisms and their surroundings. …”
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Terlipressin at esophageal varicose bleeding at liver cirrhosis with portal hypertension syndrome by B. N. Kotiv, I. I. Dzidzava, D. P. Kashkin, A. V. Smorodsky, A. V. Slobodyanik, S. A. Soldatov, M. V. Koldin

“…In both groups injection of studied agents was accompanied by change of parameters of central hemodynamics. …”
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Integrating WHO thinking healthy programme for maternal mental health into routine antenatal care in China: a randomized-controlled pilot trial by Anum Nisar, Juan Yin, Jingjun Zhang, Wenli Qi, Jie Yu, Jiaying Li, Xiaomei Li, Atif Rahman

“…Our primary findings indicated that this nurse-delivered intervention was feasible to integrate into routine antenatal care and was well-received by both the women and the delivery agents. Although the study was not designed to detect differences between the intervention and control groups, we observed positive trends towards reductions in anxiety and depressive symptoms favoring the intervention arm. …”
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