Whole-genome sequencing-based characterization of Salmonella enterica Serovar Enteritidis and Kentucky isolated from laying hens in northwest of Iran, 2022–2023 by Shirin Vakili, Mehri Haeili, Adel Feizi, Kiarash Moghaddasi, Maryam Omrani, Arash Ghodousi, Daniela Maria Cirillo

“…The aminoglycoside resistance gene aac(6′)-Iaa was the most frequently detected gene being present in all serovars, but it did not confer phenotypic resistance to corresponding agents (tobramycin and amikacin). All S. Enteritidis isolates carried a single GyrA D87N/Y substitution. …”
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Chronic Myeloid Leukemia: Part I—Real-World Treatment Patterns, Healthcare Resource Utilization, and Associated Costs in Later Lines of Therapy in the United States by Ehab L. Atallah, Rodrigo Maegawa, Dominick Latremouille-Viau, Carmine Rossi, Annie Guérin, Eric Q. Wu, Pallavi Patwardhan

“…**Background:** Despite advances in tyrosine kinase inhibitor (TKI) therapy for chronic myeloid leukemia in chronic phase (CML-CP), a sizeable proportion of patients with CML-CP remains refractory or intolerant to these agents. **Objectives:** Treatment patterns, healthcare resource utilization (HRU), and costs were evaluated among patients with CML who received third or later lines of therapy (3L+), a clinical population that has not been previously well-studied, with unmet treatment needs as TKI therapy has repeatedly failed. …”
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Carboplatin-resistance-related DNA damage repair prognostic gene signature and its association with immune infiltration in breast cancer by Shuwen Dong, Anqi Li, Ruixin Pan, Jin Hong, Zheng Wang, Kunwei Shen

“…Compared to the control group, TONSL-knockdown cell lines exhibited a diminished response to DNA-damaging agents, marked by a notable increase in DNA damage levels and enhanced drug sensitivity. …”
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Bioinformatics-Based Exploration of the Ability of Ginkgetin to Alleviate the Senescence of Cardiomyocytes After Myocardial Infarction and Its Cardioprotective Effects by Li H, Wei D, Cao H, Han Y, Li L, Liu Y, Qi J, Wu X, Zhang Z

“…There is a need to identify more effective therapeutic agents to minimize cardiomyocyte damage and enhance cardioprotection. …”
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Treatment of neovascular age-related macular degeneration: one year real-life results with intravitreal Brolucizumab by Settimio Rossi, Carlo Gesualdo, Ernesto Marano, Raffaele Perrotta, Maria Consiglia Trotta, Antonio Del Giudice, Francesca Simonelli

“…Intravitreal anti-vascular endothelial growth factor (anti-VEGF) agents have transformed nAMD treatment, with Brolucizumab emerging as a promising therapy. …”
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Reduction of liver abscesses in feedlot cattle by the addition of tannins on diet by C. CABRAL, E.A. REDONDO, Fernando DELGADO

“…La presencia de lesiones microscópicas en bovinos del TG sugirió que el tratamiento controla la progresión del cuadro, pero no la colonización del agente causal. Los mecanismos implicados permanecen desconocidos y deberán analizarse en futuros estudios.…”
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Cytotoxic and cytostatic activity of five new imidazotetrazine derivatives on breast cancer cell cultures MDAMB231, BT474, and MCF-7 by Ahmed Hamid Al-Humairi, Svetlana E. Sitnikova, Valery V Novochadov

“…Introduction: The work presents the results of the study of new imidazotetrazine derivatives to establish the possibility of using them as anticancer agents, including for chemotherapy of metastatic breast cancer. …”
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Comparative efficacy of different drugs in acute heart failure with renal dysfunction: a systematic review and network meta-analysis by Qianyu Lv, Qian Wu, Yingtian Yang, Lanlan Li, Xuejiao Ye, Shihan Wang, Yanfei Lv, Manshi Wang, Yushan Li

Subjects: “…acute heart failure…”
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Efectividad de la larva Hermetia illucens como organismo bioconversor de excretas humanas en condiciones de laboratorio by Verónika Vera Marmanillo, Daniel Enrique Rado Arenas, Renzo Rodrigo Quiñones Loaiza, Adriana Jiménez Morveli

“…Se evaluó la disminución de agentes microbiológicos por SEM, sin quistes de protozoarios descritos por análisis microbiológico (Blastocystis hominis) y disminución del volumen de las excretas.…”
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Determination of antioxidant and phytochemical properties of premix extract of brown macroalgae Padinaaustralis, Sargassum licifolium and Stoechospermum marginatum from Chabahar co... by Paria Akbary

“…Most importantly, they contain a wide range of bioactive agents such as phenols, sterols and flavonoids, many of which are not commonly found in land plants. …”
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Selective and persistent toxicity of seven insecticides to five egg parasitoids of Spodoptera frugiperda by Hao-Ran Li, Cheng-Yang Li, Peng Dai, Lian-Sheng Zang, Nicolas Desneux, Wei Xu

“…As part of an integrated pest management system, biological control agents can be used against S. frugiperda, especially egg parasitoids. …”
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TORMENTA DE POLVO: REFLEXIONES DE UN DÍA DE CAMPO EN LA PATAGONIA by Javier Grosso

“…El agua que ocupaba la zona, ahora desierta, impidió el crecimiento de vegetales que actúan como sostén del suelo, actuando ella misma como agente retensivo al otorgar peso a las partículas. …”
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Immunometabolic alterations in type 2 diabetes mellitus revealed by single-cell RNA sequencing: insights into subtypes and therapeutic targets by Huahua Li, Lingling Zou, Zhaowei Long, Junkun Zhan, Junkun Zhan

“…Drug enrichment analysis highlighted potential therapeutic agents targeting these TFs and related pathways, including Suloctidil, Chlorpropamide, and other compounds modulating inflammatory and metabolic pathways.ConclusionThis study underscores significant immunometabolic dysfunction in T2DM, characterized by alterations in immune cell composition, metabolic pathways, and intercellular communication. …”
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Dye-based fluorescent organic nanoparticles made from polar and polarizable chromophores for bioimaging purposes: a bottom-up approach by Daniel, Jonathan, Dal Pra, Ophélie, Kurek, Eleonore, Grazon, Chloé, Blanchard-Desce, Mireille

“…Such dFONs can be used as ultrasensitive contrast agents for in vivo two-photon angiography in small animals, while hyper-bright NIR-emitting FONs, that show remarkable photostability and excellent biocompatibility, can be successfully imaged and tracked at the single particle level in water. …”
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New acorane-sesequiterpenes and anti-retinoblastoma constituents from the marine algicolous fungus Trichoderma harzianum NTU2180 guided by molecular networking strategy by Andrea Gu, Fan-Li Lin, Chung-Kuang Lu, Tz-Wei Yeh, Yih-Fung Chen, Ho-Cheng Wu, Tzong-Huei Lee

“…Abstract Background Trichoderma species, known as biocontrol agents against plant diseases, contain diverse compounds, especially terpenoids, with various bioactivities. …”
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Explorando a realidade socioeconômica e alimentar em comunidades desfavorecidas: relato de experiência by Víctor Câmara Gusmão Cardoso, João Gabriel Alves Leite, Rafael Cabral de Carli, Sarah Carolyne Lima Farias, Maria das Neves Dantas da Silveira Barros

“…Aplicou-se formulários para coleta de queixas ligadas a alguma doença, conteúdo da alimentação e condições de moradia, além da realização de exame físico e de um eletrocardiograma. …”
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Ictus en pacientes geriátricos ingresados en una sala de cuidados intermedios de medicina by Rafael Venegas Rodríguez, Wilfredo Hernández Pedroso, Daily Chacón Montano, Ricardo González Mesana, Raúl Santana Sánchez, Efraín Chibás Ponce

“…Esto exige un trabajo de rehabilitación importante para alcanzar una calidad de vida aceptable. …”
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Efficacy and safety of FOLFIRI/aflibercept in second‐line treatment of metastatic colorectal cancer in a real‐world population: Prognostic and predictive markers by Ana Fernández Montes, Nieves Martínez Lago, Marta Covela Rúa, Juan de la Cámara Gómez, Paula González Villaroel, José Carlos Méndez Méndez, Mónica Jorge Fernández, Mercedes Salgado Fernández, Margarita Reboredo López, Guillermo Quintero Aldana, María Luz Pellón Augusto, Begoña Graña Suárez, Jesús García Gómez

“…Results Patients had good general status (PS 0‐1 96.2%), tumours were mostly RAS‐mutant (75.6%), synchronous (71.8%), and left‐sided (71.8%). Prior therapy included bevacizumab (47.4%) and anti‐EGFR agents (12.8%). …”
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Synthesis, Antibacterial, Antioxidant, and Molecular Modeling Studies of Novel [2,3′-Biquinoline]-4-Carboxylic Acid and Quinoline-3-Carbaldehyde Analogs by Zeleke Digafie, Yadessa Melaku, Zerihun Belay, Rajalakshmanan Eswaramoorthy

“…To tackle this problem, developing new effective chemotropic agents is urgently needed. Hence, this project aims to design, synthesize, and evaluate their antibacterial and antioxidant activities of new series of [2,3′-biquinoline]-4-carboxylic acid and quinoline-3-carbaldehyde analogs. …”
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Identification of SETD4 as an Onco‐Immunological Biomarker Encompassing the Tumor Microenvironment, Prognoses, and Therapeutic Responses in Various Human Cancers by Yuyun Zhong, Ruiqi Wang, Zijie Huang, Zhaoting Hu, Bin Peng, Bin Chen, Liyue Sun

“…Notably, we identified several potential agents targeting SETD4. Conclusions This study demonstrates that SETD4 is an immune‐oncogenic molecule in multiple cancers, with the potential to be a diagnosis, prognosis, and targeted therapy marker.…”
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