Antimicrobial photodynamic inactivation of Pseudomonas aeruginosa persister cells and biofilms by Mona Mahmoud, Peter Richter, Philipp Arnold, Michael Lebert, Andreas Burkovski

“…Pseudomonas aeruginosa is a hard-to-treat human pathogen for which new antimicrobial agents are urgently needed. P. aeruginosa is known for forming biofilms, a complex aggregate of bacteria embedded in a self-generated protective matrix that enhance its resistance to antibiotics and the immune system. …”
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Conocimiento de la Rehabilitación Basada en la Comunidad por parte de fonoaudiólogos de la región de Valparaíso, Chile by Manuel del Campos Rivas, Angélica Pilar Silva Ríos, Rodrigo Pérez Pérez

“…Un 75% de los consultados refiere el ser agente de salud como eje central de su labor y  un 25% comunica que sus responsabilidades han de centrarse en la ejecución de talleres comunitarios. …”
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Infusion of Autologous Retrodifferentiated Stem Cells into Patients with Beta-Thalassemia by Ilham Saleh Abuljadayel, Tasnim Ahsan, Huma Quereshi, Shakil Rizvi, Tamseela Ahmed, Sabiha Mirza Khan, Jawaid Akhtar, Ghazi Dhoot

“…Fetal hemoglobin switching agents have been proposed to treat genetic blood disorders, such as sickle cell anemia and beta-thalassemia, in an effort to compensate for the dysfunctional form of the beta-globin chain in adult hemoglobin. …”
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Book spreaders in the towns of Samogitian principality in the XVIII century by Elmantas Meilus

“…They were delivered by agents throughout the whole principality. There was permission to sell not only books not banned by the Catholic Church but also holy pictures and other items necessary for religious rites. …”
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The Effects of Trenbolone Supplementation on The Extremity Bones in Running Rats by Ali Sarı, Sefa Lök

“…The use of ergogenic agents is increasing among athletes for doping in order to increase physical performance and change external image. …”
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BIOMARCADORES ASEQUIBLES DE DEMENCIA FRONTOTEMPORAL: UN ESTUDIO DE CLASIFICACIÓN BASADO EN LA CONECTIVIDAD DE REDES CEREBRALES by Martín Dottori, Lucas Sedeño, Miguel Martorell Caro, Florencia Alifano, Eugenia Hesse, Ezequiel Mikulan, Adolfo M. García, Marcela Contreras-Torregrosa, Edinson Muñoz, Amparo Ruiz-Tagle, Patricia Lillo, Andrea Slachevsky, Cecilia Serrano, Daniel Fraiman, Agustín Ibáñez

“…Por otra parte, mientras que las pruebas neuropsicológicas llevaron a una discriminación aceptable entre los pacientes con vcDFT y los del grupo control, la adición de los resultados de conectividad aumentó el poder de clasificación. …”
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La autoayuda en tiempos de la COVID-19 by Idania María Otero-Ramos, Evelyn Fernández-Castillo, Diana Rosa Rodríguez-González, Annia Esther Vizcaíno-Escobar

“… Introducción: Ante la presencia del SARS-CoV-2, nuevo coronavirus y agente causal de la COVID-19, se ha desencadenado a nivel mundial una pandemia traducida en millones de enfermos y altas tasas de letalidad. …”
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Effect of phycocyanin and phycoerythrin on antioxidant and antimicrobial activity of refrigerated low-fat yogurt and cream cheese by Azadeh Ahmadi, Seyed Amir Ali Anvar, Bahareh Nowruzi, Leila Golestan

“…This study marks the initial effort to employ PE and PC derived from Nostoc sp. and Spirulina sp. as antioxidant and antimicrobial agents in the food industry.…”
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LA COMPLEJIDAD DE LOS ECOSISTEMAS DEL NORTE DE LA PROVINCIA DE MENDOZA by Moria Alessandro, María Codes, Natalia Pucciarelli, Gabriela Sari, Fernanda Soler, Matias Rodriguez, Jésica Cabanillas, Jorge Fernández

“…Las hipótesis planteadas afirman que, en las escalas de ecosistemas, el clima es el denominador común que organiza la distribución de los mismos; y que existen agentes degradadores en todos los niveles de análisis. …”
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Usefulness of Measuring Thiopurine Metabolites in Children with Inflammatory Bowel Disease and Autoimmunological Hepatitis, Treated with Azathioprine by Katarzyna Bąk-Drabik, Piotr Adamczyk, Justyna Duda-Wrońska, Dominika Dąbrowska-Piechota, Anna Jarzumbek, Jarosław Kwiecień

“…Thiopurines, such as azathioprine (AZA) and 6-mercaptopurine (6-MP), are immunomodulatory agents, used for the maintenance of remission in children with inflammatory bowel disease (IBD)—Crohn’s disease (CD) and ulcerative colitis (UC), as well as with autoimmunological hepatitis (AIH). …”
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Identification of prognostic biomarker of non-small cell lung cancer based on mitochondrial permeability transition-driven necrosis-related genes and determination of anti-tumor ef... by Zhifei Ma, Wen Chen, Aiping Zhang, Xiaokang Shen, Lin Zheng

“…Correlations between these biomarkers and immune cell infiltration, immune checkpoints, and chemotherapeutic agents were observed. Expression levels of MPTDN-related biomarkers were detected using RT-qPCR in NSCLC tissues and cells. …”
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Possibility of Using NO Modulators for Pharmacocorrection of Endothelial Dysfunction After Prenatal Hypoxia by Igor Belenichev, Olena Popazova, Oleh Yadlovskyi, Nina Bukhtiyarova, Victor Ryzhenko, Sergii Pavlov, Valentyn Oksenych, Oleksandr Kamyshnyi

“…This emphasizes the potential of therapeutic agents with NO modulator properties, such as Thiotriazoline, Angiolin, Mildronate, and L-arginine, in the treatment of PH. …”
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Interaction between Nuclear Receptor and Alpha-Adrenergic Agonist Subtypes in Metabolism and Systemic Hemodynamics of Spontaneously Hypertensive Rats by Sheryar Afzal, Munavvar Abdul Sattar, Ibrahim Albokhadaim, Ali Attiq, Mahmoud Kandeel, Aimi Syamima Abdul Manap, Sameer M. Alhojaily

“…Partial and full PPAR-γ agonists have shown promising effects and antihypertensive and antidiabetic agents through increased plasma adiponectin concentration. …”
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Educación jurídica e innovación tecnológica: un ensayo crítico by Daniel Bonilla Maldonado

“…Las primeras dos respuestas están relacionadas directamente con agentes del mercado que demandan educación jurídica: los estudiantes de derecho y las firmas de abogados. …”
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Clinical perspective on antihypertensive drug treatment in adults with grade 1 hypertension and low to moderate cardiovascular risk: an international expert consultation by Alberto Morales Salinas

“…Una pregunta en debate es si la hipertensión arterial grado 1 (140-159/90-99 mm Hg) con riesgo cardiovascular (RCV) total bajo (mortalidad cardiovascular <1% a los 10 años) a moderado (mortalidad cardiovascular >1% and <5% a los 10 años) debe ser tratada con agentes antihipertensivos. Un proceso de consulta virtual internacional fue realizado para resumir las opiniones de los expertos seleccionados. …”
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Metagenomics: a new frontier for routine pathology testing of gastrointestinal pathogens by Nicola Z. Angel, Mitchell J. Sullivan, Areej Alsheikh-Hussain, Liang Fang, Samantha MacDonald, Alena Pribyl, Blake Wills, Gene W. Tyson, Philip Hugenholtz, Donovan H. Parks, Paul Griffin, David L. A. Wood

“…However, thorough testing for a wider range of causal agents is time consuming and remains limited to a subset of pathogenic organisms. …”
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Intoxicaciones agudas por medicamentos consumidos con fines de abuso by Jurek Guirola Fuentes, Liudmila Pérez Barly, Yamilet García González, Alina Díaz Machado, Odalys Gobín Puerto

“…La serie incluyó 578 pacientes con intoxicaciones agudas con fines de abuso, donde el agente causal fueron los medicamentos. Se recopilaron los datos sociales y biológicos, formas de consumo, grupos farmacológicos, manifestaciones clínicas, aspectos de la toxicocinética y la toxicodinamia. …”
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Activity of ceftolozane/tazobactam and comparators against gram-negative bacilli: Results from the Study for Monitoring Antimicrobial Resistance Trends (SMART – Brazil), 2018‒2021... by Amanda Azevedo Bittencourt, Vinicius Lima Faustino, Paula de Mendonça Batista, Lays Paulino Leonel, Marina Della Negra de Paula, Thales José Polis

“…Colistin and ceftolozane/tazobactam were the most active β-lactam agents tested against P. aeruginosa in 2018‒2019 (99.3 % and 88.8 %) and 2020‒2021 (100 % and 92.8 %), including ceftazidime and meropenem resistant isolates. β-lactamase encoding gene characterization was carried out and both carbapenemases and Extended-Spectrum β-Lactamase (ESBL) producers were found in E. coli, K. pneumoniae and P. aeruginosa isolates. …”
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Marcadores infecciosos asociados a factores demográficos en donantes de sangre peruanos by Cleofe del Pilar Yovera-Ancajima, William Cruz-Gonzales, Gloria Cruz-Gonzales, Jeel Moya-Salazar

“…La población la conformaron los 11 936 donantes que fueron tamizados para 7 agentes infecciosos según el Programa Nacional de Hemoterapia y Banco de Sangre. …”
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Single-cell transcriptomics analysis reveals dynamic changes and prognostic signature in tumor microenvironment of PDAC by Yongsheng Li, Zhilong Ding, Tingxin Cheng, Yihuai Hu, Fei Zhong, Shiying Ren, Shiyan Wang

“…Furthermore, our analysis revealed significant interactions between cells at different stages of PDAC and identified three promising therapeutic agents (XR-11576, Ixabepilone, and AMONAFIDE) based on correlated genes. …”
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