Neurological history both twinned and queried by generative artificial intelligence by Jung-Hyun Lee, Jung-Hyun Lee, Jung-Hyun Lee, Eunhee Choi, Sergio L. Angulo, Sergio L. Angulo, Robert A. McDougal, Robert A. McDougal, Robert A. McDougal, Robert A. McDougal, William W. Lytton, William W. Lytton, William W. Lytton

“…A large language model (LLM) could be utilized as a digital twin which could enhance queryable electronic medical record (EMR) systems and provide healthcare conversational agents (HCAs) to replace waiting-room questionnaires.MethodsIn this observational pilot study, we presented verbatim history of present illness (HPI) narratives from published case reports of headache, stroke, and neurodegenerative diseases. …”
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Enhancing feature selection for multi-pose facial expression recognition using a hybrid of quantum inspired firefly algorithm and artificial bee colony algorithm by Mu Panliang, Sanjay Madaan, Siddiq Ahmed Babikir Ali, Gowrishankar J., Ali Khatibi, Anas Ratib Alsoud, Vikas Mittal, Lalit Kumar, A. Johnson Santhosh

“…The proposed algorithm uses the attributes of both the QIFA and ABC algorithms to enhance search space exploration, thereby improving the robustness of features in FER. The firefly agents initially move toward the brightest firefly until identified, then search transition to the ABC algorithm, targeting positions with the highest nectar quality. …”
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Antimycobacterial Activity, Synergism, and Mechanism of Action Evaluation of Novel Polycyclic Amines against Mycobacterium tuberculosis by Erika Kapp, Jacques Joubert, Samantha L. Sampson, Digby F. Warner, Ronnett Seldon, Audrey Jordaan, Margaretha de Vos, Rajan Sharma, Sarel F. Malan

“…Mycobacterium tuberculosis has developed extensive resistance to numerous antimycobacterial agents used in the treatment of tuberculosis. Insufficient intracellular accumulation of active moieties allows for selective survival of mycobacteria with drug resistance mutations and accordingly promotes the development of microbial drug resistance. …”
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Phytomedicinal armamentarium: A review of inula racemosa-derived alantolactones and isoalantolactones in anticancer therapy by Joshi Gaurav Santoshrao, Smriti Jamwal, Rakesh Kumar, Ekta Bisht, Bisen Harsh Krishnakumar, Shreya Katoch, R.K. Asrani

“…Conclusion: Alantolactone and isoalantolactone from Inula racemosa show promising potential as anti-cancer agents. Their diverse mechanisms of action and minimal side effects position them as candidates for further research and development. …”
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Control in vitro e in vivo de Thielaviopsis paradoxa y Colletotrichum musae con biofungicidas en frutos de banano orgánico by René Aguilar-Anccota, Silverio Apaza-Apaza, Edgar Maldonado D., Yuri H. Calle-Cheje, Robert Rafael-Rutte, Kenny R. Montalvo M., Mercedes M. More-Yarleque, Ricardo Chávez C., Pierina L. Chuquicusma C., Arturo Morales-Pizarro

“…Los productos usados fueron: extracto de orégano, ácido cítrico; ácido ascórbico, bioflavonoides; biofertilizante y aceite del árbol de té. In vitro se utilizó el método del “medio envenenado”. …”
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Bursera graveolens en matorral desértico con fines de desarrollo forestal sostenible: Volumetría, peso, inventario forestal y regeneración natural by Miguel Antonio Puescas Chully, Eber Leopoldo Herrera Palacios, José Antonio Moscol Ortiz, Hidalgo Sandoval Eder E., William Huaman Huaman

“…Con el propósito de mejorar la calidad de vida a las poblaciones locales, entre ellas la Asociación de agricultores y ganaderos de la localidad La Pampa-Quebrada Seca, Casitas, Tumbes, mediante el aprovechamiento sostenible de madera seca de palo santo para la extracción de aceite esencial y sus subproductos. El objetivo fue determinar el peso de madera seca de palo santo en 1 m3 por hectárea in situ en el bosque matorral desértico comprendido en el plan operativo anual (1 POA) de 100 ha del plan general de manejo forestal (PGMF) de 500 ha. …”
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Ionized and total magnesium levels and health outcomes in patients with type 2 diabetes mellitus by Juhaina Salim Al-Maqbali, Salwa Al Harasi, Qasim Al Mamary, Henrik Falhammar, Ibrahim Al-Zakwani, Mohammed Al Za’abi, Abdullah M. Al Alawi

“…The study included adult patients with T2DM treated with oral hypoglycemic agents (OHA), insulin, glucagon-like-peptide 1 (GLP-1) injections or their combinations. …”
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Anticonvulsant Effects of Synthetic <i>N</i>-(3-Methoxybenzyl)oleamide and <i>N</i>-(3-Methoxybenzyl)linoleamide Macamides: An In Silico and In Vivo Study by Karin Jannet Vera-López, Jorge Alberto Aguilar-Pineda, Rodrigo Martín Moscoso-Palacios, Gonzalo Davila-Del-Carpio, José Luis Manrique-Murillo, Badhin Gómez, Minerva González-Melchor, Rita Nieto-Montesinos

“…In this context, the use of macamides as therapeutic agents in neurological diseases has increased in recent years. …”
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Differential Regulation of Methylation-Regulating Enzymes by Senescent Stromal Cells Drives Colorectal Cancer Cell Response to DNA-Demethylating Epi-Drugs by Khushboo Agrawal, Viswanath Das, Natálie Táborská, Ján Gurský, Petr Džubák, Marián Hajdúch

“…While the effects of these epi-drugs alone or in combination with other anticancer therapies are well described, the influence of stromal cells and their secretome on cancer cell response to these agents remain elusive. In this study, we determined the effect of normal and senescent colon-unassociated fibroblasts and their conditioned medium on colorectal cancer (CRC) cell response to AZA and DAC using a cell-based DNA demethylation reporter system. …”
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Influencia de cepas bacterianas y condiciones de incubación en la viabilidad y calidad de ensilados biológicos para su uso en la producción animal by Yicson Javier Arevalo Aguirre, Javier Querevalú Ortiz, Gloria María Ochoa Mogollón, Héctor Sánchez Suárez

“…La estabilidad a partir del día 10 con temperatura del EB de 32 °C, la cantidad de microorganismos BAL y los no deseables, estuvieron dentro del límite aceptable para alimento fermentados, el valor de la proteína de 33,8% a 36,7% en D. conceptione y 33% a 33,16% en C. obscurus. …”
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Dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) in patients with chronic coronary artery disease (CAD) - current state of knowledge and perspective... by Hubert Bochenek, Anna Bielicka, Michał Bzoma, Julia Gugulska, Irmina Czerepak, Marcin Kapij, Karolina Niewczas, Adrianna Brzozowska

“…Alternatives include shortening DAPT to 1–3 months for patients with high bleeding risk or intensifying it with stronger antiplatelet agents like ticagrelor or prasugrel for those at high ischemic risk. …”
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Involvement of HLADQA1*05 in Patients with Inflammatory Bowel Disease Treated with Anti-TNF Drugs by Anna Pau, Ilaria Galliano, Elisa Barnini, Maddalena Dini, Antonio Pizzol, Alice Ponte, Stefano Gambarino, Pier Luigi Calvo, Massimiliano Bergallo

“…<i>Conclusions</i>: Our study suggests that the HLA-DQA1*05 allele does not increase the risk of secondary loss of response to anti-TNF therapy, likely because most patients were on a combination of anti-TNF agents and immunomodulators, which can lower anti-drug antibody production. …”
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A new peptide inhibitor of C1QBP exhibits potent anti‐tumour activity against triple negative breast cancer by impairing mitochondrial function and suppressing homologous recombina... by Xingxing Li, Yue Wu, Min Zhang, Fengliang Wang, Hong Yin, Yanrong Zhang, Shuli Zhao, Jiehua Ma, Mingming Lv, Cheng Lu

“…Nevertheless, to date, no pharmacological agents capable of directly targeting and inducing the degradation of C1QBP have been identified. …”
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Nutrient Formulation—A Sustainable Approach to Combat PRSV and Enhance Productivity in Papaya by Kavitha Chinnasamy, Naveen Kumar Krishnan, Moganapathi Balasubramaniam, Reena Balamurugan, Pugalendhi Lakshmanan, Kalarani M. Karuppasami, Manoranjitham S. Karuppannan, Elaiyabharathi Thiyagarajan, Senthil Alagarswamy, Saraladevi Muthusamy

“…To combat PRSV and enhance productivity, a nutrient formulation was developed by combining organic, inorganic nutrient sources with biocontrol agents to improve the health and vigor of the plants. …”
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Novel Perspectives for Sensory Analysis Applied to Piperaceae and Aromatic Herbs: A Pilot Study by Isabella Taglieri, Alessandro Tonacci, Guido Flamini, Pierina Díaz-Guerrero, Roberta Ascrizzi, Lorenzo Bachi, Giorgia Procissi, Lucia Billeci, Francesca Venturi

“…Indeed, spices as well as aromatic herbs are to be considered not only for their important values of antimicrobial agents or flavor enhancers everybody knows, but also, thanks to their olfactory and gustatory spectrum, as drivers to stimulate the consumers’ memories and, in a stronger way, emotions. …”
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Molecular Identification and Antimicrobial Potential of Streptomyces Species from Nepalese Soil by Karan Khadayat, Dawa Dindu Sherpa, Krishna Prakash Malla, Sunil Shrestha, Nabin Rana, Bishnu P. Marasini, Santosh Khanal, Binod Rayamajhee, Bibek Raj Bhattarai, Niranjan Parajuli

“…The necessity of alternative antimicrobial agents against multidrug-resistant pathogens is indispensable. …”
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Selective Serotonin Reuptake Inhibitors: Antimicrobial Activity Against ESKAPEE Bacteria and Mechanisms of Action by Thiago Hideo Endo, Mariana Homem de Mello Santos, Sara Scandorieiro, Bruna Carolina Gonçalves, Eliana Carolina Vespero, Márcia Regina Eches Perugini, Wander Rogério Pavanelli, Gerson Nakazato, Renata Katsuko Takayama Kobayashi

“…<b>Conclusions:</b> These findings indicate that sertraline and paroxetine could serve as alternative treatments against multidrug-resistant bacteria, as well as efflux pump inhibitors (EPIs), and they support further development of antimicrobial agents based on these compounds.…”
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Risk factors for Clostridioides difficile infection among patients diagnosed with inflammatory intestinal and rheumatological diseases in the biologic era by Helena Martínez-Lozano, Paula Saralegui-Gonzalez, Elena Reigadas, Pablo Ramón Fueyo-Peláez, Aurea García-García, José Miranda-Bautista, Luis Alcalá, Juan Carlos Nieto, María Elena Lobato-Matilla, Ignacio Marín-Jiménez, Patricia Muñoz, Luis Menchén

“…Although the subgroup of IBD patients receiving biologics showed a higher incidence of CDI compared to unexposed IBD patients, biologic therapy was not an independent risk factor for CDI in the logistic regression model; nevertheless, patients who received 3 or more biologic agents had a significantly higher risk for CDI (OR: 3.09, CI 95% 1.13–8.47, p = 0.028). …”
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Antifungal Activity of Genistein Against Phytopathogenic Fungi <i>Valsa mali</i> Through ROS-Mediated Lipid Peroxidation by Fangjie Li, Chen Yang, Maoye Li, Su Liu, Kuo Xu, Xianjun Fu

“…This finding has the potential to contribute to the development of novel biological control agents for industrial crops.…”
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Psoriasis increases the risk of Sjögren’s syndrome: evidence from a propensity score-matched cohort study and transcriptomic analysis by Zijian Kang, Yu Du, Ran Cui, Qian Wang, Miao Chen, Yu-Hsun Wang, James Cheng‐Chung Wei, Sheng-Ming Dai

“…Patients with psoriatic arthritis (PsA) and those treated with biological agents had an even higher risk of developing SS. Transcriptomic analysis revealed potential shared pathogenesis of psoriasis and SS involving cellular proliferation, immune cell recruitment, cytokine secretion, and the interferon response to viral infections. …”
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