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41381
El derecho a la paz con enfoque territorial y la convivencia escolar en Colombia: Estudio de caso comparado en la Ciudad de medellín
Published 2023-12-01“…Presenta a Medellín como una ciudad que requiere procesos de construcción y garantías del Derecho a paz territorial que no sean solo responsabilidad de los agentes del Estado sino también de las escuelas. Se plantea como objetivo principal comprender la relación entre el derecho a la paz con enfoque territorial y la convivencia escolar a partir de un estudio de caso comparado en la ciudad de Medellín, Colombia. …”
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41382
hERG activators exhibit antitumor effects in breast cancer through calcineurin and β-catenin-mediated signaling pathways
Published 2025-01-01“…Notably, combining SDUY429 or SDUY436 with the AKT inhibitor MK-2206 produced synergistic anti-proliferative effects.ConclusionThese findings suggest that hERG activators hold promise as new potential therapeutic agents for the treatment of breast cancer, paving the way for future investigations into their clinical applications.…”
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41383
Chronic Stress Mediates Inflammatory Cytokines Alterations and Its Role in Tumorigenesis
Published 2025-01-01“…This ongoing inflammation further enhances the activity of these transcription factors, which serve multiple roles: they act as pro-inflammatory agents in inflammatory cells, maintaining chronic inflammation; as oncogenic transcription factors in premalignant cells, promoting cancer initiation; and as pro-differentiation transcription factors in tumor-infiltrating immune cells, facilitating cancer progression. …”
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41384
HMOX1 as a potential drug target for upper and lower airway diseases: insights from multi-omics analysis
Published 2025-01-01“…Molecular docking was used to identify potential therapeutic agents. Results HMOX1 expression was significantly elevated in CRSwNP. …”
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41385
Isolation and Evaluation of Clinically Important Acinetobacter Baumannii From Intensive Care Unit Samples
Published 2021-09-01“…However, two antimicrobial agents which were Colistin and Tigecycline produced 0 and 2.4 % resistance to A. baumannii respectively, which were considered the most used choices to treat A. baumannii infections. …”
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41386
Efficacy of Inhaled Steroid Over Systemic Steroid in Stabilizing Acute Asthma in Emergency Room
Published 2025-02-01“…Background: Acute exacerbation of asthma is one of the most common illnesses presenting to Emergency Department. …”
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41387
LA EDUCABILIDAD UN PROCESO CONSTANTE EN CONSTRUCCIÓN PARA EL DESARROLLO HUMANO
Published 2024-04-01“… El presente artículo de reflexión en su objetivo central, aborda un recorrido sobre las distintas problemáticas que aquejan a la acción educativa, el cómo el educador ha dejado de ser un agente difusor de la cultura, el encargado de reconocer y respetar la diversidad de las regiones, del entorno y/o su contexto, el protagonista para establecer un debate en el aula y convertirse así en un interlocutor que motive a la duda y la pregunta, para en muchos casos ser un transmisor o divulgador de conocimientos. …”
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41388
Contribution of vitamin B 6 deficiency to anemia in children on regular hemodialysis
Published 2025-01-01“…In addition, erythropoiesis-stimulating agents (ESA) and iron supplementation are considered the cornerstones in the management of anemia. …”
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41389
Caracterización de las respuestas relativas de híbridos de girasol en ensayos oficiales del centro y norte de la Argentina
Published 2005-01-01“…Se estimaron los componentes de varianza, se compararon estrategias de selección en función de la heredabilidad en sentido amplio y se aplicaron análisis de patrones sobre matrices de genotipos × ambientes. Para rendimiento de aceite, la interacción G×E explicó 3.46 veces más variabilidad que el efecto genotípico. …”
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41390
Occurrence of Florfenicol and Linezolid Resistance and Emergence of optrA Gene in Campylobacter coli Isolates from Tunisian Avian Farms
Published 2024-01-01“…Isolates were tested for their susceptibility to antimicrobial agents using the Kirby–Bauer disk diffusion assay. …”
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41391
Magnetoelectric Extracellular Vesicle Latency-Targeting (MELT) Nanotherapeutic for the Block-Lock-and-Kill HIV Eradication Strategy
Published 2025-01-01“…GFP expression in HC69 at rest is low (GFP<sup>Lo</sup>), and upon exposure to LTR, transcription-activating agents (i.e., TNF-α) are induced to be high expressing (GFP<sup>Hi</sup>). …”
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41392
Phenotypic and Genotypic Identification of Antimicrobial Resistance amongst the Campylobacter jejuni and Campylobacter coli Strains Isolated from Raw Milk of Animal Species
Published 2024-01-01“…The prevalence of simultaneous resistance toward more than 4 antimicrobial agents amongst the C. jejuni and C. coli isolates was 46% and 16.66%, respectively. …”
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41393
The Immunosuppressant Fingolimod (FTY720) for the Treatment of Mechanical Force-Induced Abnormal Scars
Published 2020-01-01“…Therefore, its local immunosuppressive mechanisms differ from those of conventional immunosuppressive agents. Topical FTY720 can be a novel therapeutic option for abnormal scars that are difficult to control with corticosteroids. …”
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41394
Contrast Medium Use in Computed Tomography for Patients Presenting with Headache: 4-year Retrospective Two-Center Study in Central and Western Regions of Ghana
Published 2022-01-01“…Further studies to improve the knowledge of agents, mechanism of action, and safety of contrast media used among practitioners in Ghana is recommended.…”
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41395
Cytotoxic mechanisms of pemetrexed and HDAC inhibition in non-small cell lung cancer cells involving ribonucleotides in DNA
Published 2025-01-01“…HDAC inhibition apparently exacerbates cytotoxicity of these agents by inhibiting error-free repair of misincorporated ribonucleotides in DNA. …”
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41396
Structural and free energy landscape analysis for the discovery of antiviral compounds targeting the cap-binding domain of influenza polymerase PB2
Published 2024-10-01“…These findings suggest that compound 4, along with compounds 1 and 3, holds the potential for further development into effective antiviral agents against influenza. Future studies should focus on experimental validation of these compounds and exploration of resistance mechanisms to enhance their therapeutic utility.…”
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41397
Evaluación del programa de la disciplina Morfofisiología Humana en la formación del tecnólogo en Electromedicina
Published 2014-04-01“…<strong>Fundamento</strong>: En la disciplina Morfofisiología Humana surgen una serie de interrogantes en relación con el programa de estudio, los cuales se manifiestan en los diferentes espacios docentes y metodológicos, tanto a través del análisis del trabajo metodológico materializado en la disciplina como de los agentes implicados en el proceso de enseñanza-aprendizaje.…”
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41398
Double diffusive MHD stagnation point flow of second grade fluid in non-Darcy porous media under radiation effects
Published 2025-01-01“…They are vital in the development of drag-reducing agents, damping and braking systems, food manufacturing, personal protective equipment, and the printing industry. …”
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41399
Fondo regional en América Latina y el Caribe para el desarrollo económico local y los gobiernos locales: Estrategia para la reducción de la pobreza y de la desigualdad social
Published 2006-01-01“…Los proyectos que serán implementados a través del Fondo Regional deben contribuir a la afirmación de una identidad, de elementos distintos, de una reputación propia, de características singulares que diferencien lo local dentro del universo de la globalización y que encuentran las ventajas comparativas de lo local frente a la competitividad territorial a nivel global. La formación de agentes multiplicadores en las diferentes municipalidades debe tener como eje central, la descubierta, el reconocimiento y la valorización de los activos locales, esto significa, de las potencialidades, vocaciones, oportunidades, ventajas comparativas y competitivas de cada territorio para el desarrollo económico local. …”
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41400
Oralidad y enseñanza-aprendizaje del francés a hispanohablantes
Published 2005-01-01“…En efecto, frente a la lógica de la física, se inscribe en la lógica de lo viviente: las variables y parámetros que adopta permiten determinar el sistema de errores (efectivos o latentes) sin exigir ni presuponer conductas fonatorias predeterminadas; antes bien inducen a que el aprendiente consiga resultados aceptables utilizando sus propias aptitudes y facultades personales (que, por lo demás, no pueden ser conocidas a priori). …”
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